지역사회의 동물복지문화 증진을 위한 도그파크 계획 모형

임수희,이관규,양병이,박종화,신남식,Lim Soo-Hee,Lee Gwan-Gyu,Yang Byoung-E,Park Jong-Hwa,Sin Nam-Sik 한국조경학회 2005 韓國造景學會誌 Vol.33 No.4

Korea's pet-related society has been fast growing without the base and preparations of socio-cultural animal welfare. For the most part, Korea's current public parks, in particular, have a space structure in which a lot of friction between the general public who are not fond of dogs and dog owners in public places has been happening unavoidably. A lot of countries that are taking a lead role in animal welfare have built dog parte that the general public and dogs can enjoy together. This research starts with the realization that the concept of 'dog park' needs to be introduced in Korea as more and more Koreans own dogs and other pets. This research aims to provide guidance for dog park planning by drawing a dog park planning model and to promote basics for co-existence of dogs and people in a park and set in place animal welfare early and raise the level of awareness. Total 7 types of dog put 56 planning items including dog zone, dog playground, and agility, and a selective matrix by which it is possible to select essential recommendatory optional items by each type of dog park were drawn in this research. Overall there were the highest needs in separated area for dogs in park. A dog park planning model is designed as follows. 1) To select a dog park type that was introduced. 2) To set up facilities applicable in common and planning items desired in advance by each type. 3) To zone dog park areas by the priority order of planning items that were introduced and to position necessary facilities. 4) To plan program that should be were introduced. A dog park was expected to take some positive roles such as providing opportunities to socialize dogs, activating social communities, more effective park management by participating local community members and so on.

젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun‐,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

<P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

RAW264.7 세포에서 interferon-r 및 LPS에 의해 유도되는 NO생성에 미치는 TALT-35의 영향

박종일,박경석,김종석,박지훈,윤은진,송경섭,서강식,김훈,윤완희,박승길,임규,황병두 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

TALP-35 purified from human term placenta is known to increase microtubule polymerization and stabilize the polymerized microtubule. To examine the effect of TALP-35 on immune system this study was performed. MTT assay was performed to investigate the effect of TALP-35 on the proliferation of RAW264.7 cells. TALP-35 dose dependently suppress the proliferation of RAW264.7 cells at high concentration (above 1 μM) in unstimulated cells, in case of 10 μM TALP-35 treated cells the suppression was 25% but in stimulated cells it was only 15%. Cosedimentation assay was carried out to investigate whether TALP-35 can bind to tubulin of RAW264.7, monocyte/macrophage lineage of mouse, and polymerize it. TALP-35 polymerize the tubulin of RAW264.7 cells and sedimented in dose-dependent manner. To investigate the effect of TALP-35 on the expression of iNOS protein western blotting was performed. The expression level of iNOS was decreased dose dependently in high concentration of TALP-35 treatment. To examine the activity of iNOS, secreted NO was determined by method based on Griess reaction. Interferon-γ and LPS-stimulated production of NO from RAW264.7 cells was decreased dose dependently above 0.1 μM concentration of TALP-35 and 50% is decreased at 10μM of it. This study shows TALP-35 can control cytokine induced-iNOS expression therefore it might control inflammatory diseases.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

온라인시장과 오프라인시장의 통합을 위한 전자화폐 도입 방안에 관한 연구

朴映泰,鄭種植 한국유통정보학회 2001 유통정보학회지 Vol.4 No.1

The purpose of this paper is to study the Introduction of e-money for integration on-line market and off-line market in Korea. E-money refers to the new ways of storing and transferring value arising out of the advances in microprocessor technology(e.g., wireless devices, hand held computers, robust processors) and the emergence of the Internet. Examples include digital cash, smart card, biometrics, e-checks, and internet credit cards. Fundamentally, e-money represents a shift in payments system toward distributed computing power and open networks. The Introductions are establishment of standard of e-money, expulsion of commerce network for promoting usage of e-money, enactment of the laws and articles for preventing and solving the crimes and quarrels, curtailment of arrangement of re-fund.

[논문] 칸트와 붓다, 나가르주나(龍樹)의 논리와 세계관 연구

박종식 부산대학교 인문학연구소 2011 코기토 Vol.- No.69

In this paper I will compare the Kantian philosophy with Buddha’s, Nagarjuna’s philosophy on the ground of critique in order to draw the similarities and heterogeneities of them. In Critique of Pure Reason, Kant has criticized the philosophy of realistic point of view in those days through the Copernican revolution and has justified the representative(Vorstellung) point of his own philosophy. Because of the limits of human cognition, we can’t understand the external things and internal things as things themselves. According to this view, we never understand the things themselves which exist as such. All the things we can always grasp are the things which are already interpreted through the paradigm(Kategorie). In this point of view, all the objects we can see are not the sustances which have the essences in themselves. In addition, Kant has said that we can’t know the self, freedom, the limit of the world and the absolute being because of the limits of the human ability to recognize. In this respect, Kant has wanted to resolve the important problems of epistemology criticizing the realism at those days through the new paradigm out of the Copernican revolution. Nagarjuna has also criticized the school of the realistic point of the view(說一切 有部) and justified the emptiness(空)and corelation(緣起) proving the theories, that is, ‘All the things are changing’(諸行無常), ‘Anywhere there are no selves’(諸法無我), ‘All the things are empty’(一切皆空). Nagarjuna has especially criticized the 75 unchanged substances they have insisted. In this sense, I think, Kant and Nagarjuna have commen consciousness on ciritique of the realism. But the logic and the point of view they have used in resolving the problems with which they have faced, have the same in one side and the different in other side. In this paper, I will compare Kant’s position with Nagarjuna’s position dealing with the logic, substance and ego in turn. I will have the opportunity to reflect the problems of between recognition and transcendence through the comparison of these Kant’s and Nagrjuna’s issues. 이 논문에서 필자는 칸트 철학과 붓다, 나가르주나의 철학을 비판적으로 독해해서 공통점과 차이점을 비교하고자 한다. 칸트의 『순수이성비판』은 당시의 실재론적 경향을 비판하면서 코페르니쿠스적 전회를 통해 새로운 표상론적, 관념론적 사유를 정당화하고 있다. 칸트는 외부 대상과 자아를 있는 그대로 파악할 수 없다고 주장하는데, 대상을 파악할 때 이미 인간종이 지닌 특정한 패러다임에 의존해서 파악하기 때문이다. 따라서 인간은 있는 그대로 존재하는 물자체에 결코 접근할 수 없게 된다. 모든 존재는 이미 우리가 지닌 패러다임에 의해서 해석된 존재들이기 때문이다. 우리가 인식하는 대상은 실체적, 자성적 존재가 아니라, 우리의 패러다임을 통해 해석된 2차적 존재에 불과하게 된다. 뿐만 아니라 칸트는 자아, 자유, 세계의 한계, 절대적 존재 등에 관해서는 인간 인식 능력의 한계 때문에 결코 밝힐 수 없다고 주장한다. 그러한 논제에 관한 정립이나 반정립은 둘 다 오류에 빠지게 된다. 이런 측면에서 칸트는 당시의 실재론을 비판하면서 새로운 방식으로 종래의 문제를 새롭게 해결, 해소하고자 한다. 나가르주나 역시 당시의 說一切有部의 실재론을 비판하고 諸行無常, 諸法無我, 一切皆空을 주장하면서 空과 緣起를 정당화하고 있다. 특히 고정불변하는 실체로서 75법을 주장하는 설일체유부의 自性論을 『중론』에서 八不中道說에 입각해서 비판하고 있다. 이런 측면에서 칸트와 나가르주나의 문제의식은 당시의 실재론적 경향을 비판하면서 새로운 논리를 통해서 종래의 문제를 새롭게 해결, 해소하고자 한다는 점에서 공통점을 지니고 있다. 그러나 실재론을 비판하면서 제시한 논리와 관점은 공통점과 차이점을 동시에 보이고 있다. 이 논문에서는 칸트의 입장, 나가르주나의 입장, 칸트와 나가르주나를 비교하면서 그들의 논리, 실체, 자아 문제 차례로 살펴보고자 한다. 이러한 비판적 비교 작업을 통해서 인식과 초월의 문제, 인식과 행위의 문제, 반성과 해탈의 문제 등을 반성해 볼 수 있는 계기가 될 수 있을 것이다.

현역 군인 발생을 중심으로 본 2000년도 국내 삼일열 말라리아 발생 현황

박재원,김영아,염준섭,유정식,양병국,채종일 대한감염학회 2001 감염 Vol.33 No.4

Background : Since 1997, the annual case occurrence of vivax malaria in the Republic of Korea have exceeded 1,000 cases since 1997. The military is thought to be an important source of the current outbreak. We collected various informations about malaria cases (soldiers, veterans and civilians) which occurred in 2000, and analyzed the characteristics of the current outbreak. Methods : Informations about malaria cases of soldiers, veterans and civilians, including name, age, sex, day of onset, region, etc., were collected through the National Institute of Health. Results : Out of total 4,141 cases, 1,288 (31.1%) occurred in the military, 1,273 (30.7%) occurred among the veterans, and 1,580 (38.2%) occurred among civilians. The monthly case occurrence reached its peak in early August. Areas such as Cheolwon, Yeoncheon and Paju showed the highest prevalence. Conclusion : It is considered that the current malaria outbreak has escaped from the exponential growth phase, however, more attention should be paid to prevent further spreading of malaria infection. (Korean J Infect Dis 33:280∼284, 2001)