간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

대망에 발생한 방선균증 1례

송상훈,심찬섭,이문성,김진오,조주영,김영석,문종호,이진우 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

Actinomycosis is an uncommon chronic suppurative disease characterized by multiple abscess, draining sinuses, abundant granulation, and dense fibrous tissue, caused by the actinomyces organisms. It occurs in three major sites: cervicofacial, abdominal, and thoracic. The abdomen is the second most common involved site in previous studies, and there are three ways this organism can affect the gastrointestinal tract: through a blood-borne infection, by swallowing, or by proliferation at a more distal intestinal area. Abdominal actinomycosis is an unusual disease but remains an important differential diagnosis in patients with abdominal mass. Obtaining the diagnosis is difficult and rarely made preoperatively, but provide the key to its management. Medical therapy is effetive in eradicating the disease; however, because of the large amount of reactive fibrosis formed by the infection, it requires long-term therapy. Surgical treatment may be essential in many cases, primarily when malignancy cannot be excluded or if extensive necrotic tissue exists. There are a few description for actinomycosis involving omentum. We report a case of patient with omental actinomycosis, suspected to have a malignancy requiring an exploratory laparotomy with resection.

晋州地方의 諸 氣象要素에 關한 分析的 硏究 : 第5報 雲量의 變化에 關하여 (1931~'60) 5. On the Changes of Cloud amount(1931~'60)

宋珍燮,崔文錫,金仁湖 慶尙大學校 1974 論文集 Vol.13 No.-

1931年 1月부터 1960年 12月까지 晉州地方의 雲量에 관하여 調査 分析되어진 바를 要約하면; (1) 年中 雲量의 平年値(Normals)는 4.7로 나타나고 있으며, (2) 年別 年中의 變化는 1958年의 4.0으로 最低이고 1946年과 1952年의 5.1이 最高를 보이고 있다. (3) 觀測全年의 季節別 雲量의 最低値는 冬季의 3.6이고 夏季의 6.2가 最高値를 나타내고 있다. (4) 年中의 月別 雲量가운데 12月과 1月의 3.5가 最低이고 7月의 6.8이 最高値를 보여 주고 있다. (5) 全年의 흐림, 개임 및 맑음의 日數의 百分率은 各各 42.5%, 20.3% 및 37.2%를 나타내고 있다. In the district of Jinju, the statistical reserch on the cloud amount has been carried out from the matterials which is observed at The Office of Rural Development, Gyeongnam Province from Jan. 1931 to Dec. 1960. To analyze the data numerically, the mean value has been calcuted daily, dekad and monthly during the years. The normal values are listed on the Table (1), (2), (3) and (4). The changes of dekad, monthly and yearly are plotted on Fig (1) and (2). From the tables and figures, the results are summarized as follows: 1) The annual value of the cloud amount is 4.7. 2) In the yearly changes, the lowest mean value is 4.0 in 1958 and the highest is 5.1 in 1952. 3) In the seasonal changes, the lowest mean value is 3.6 in winter and the highest is 6.2 in summer. 4) In the monthly changes, the lowest mean value is 3.5 in Dec. and the highest is 6.8 in July. 5) In the dekad changes, the lowest mean value is 3.1 inthe 3rd ekad in Fed. and the highestis 7.7 in the lst in July. 6) In the daily changes, the lowest mean value is 8.1 i Jan. 27the and the highest is 8.3 in June 29th and July 10th. 7) The percentage of annual Cloudy, Fair and Clear days are 42.5%, 20.3% adn 37.2%.

농어촌 지역의 한방의료 이용 실태에 관한 조사 : 전남 신안군 장산면을 중심으로

宋峰根,黃忠演,文錫哉 圓光大學校 韓醫學硏究所 1992 원광한의학 Vol.2 No.1

The prevalence of disease is affected by cultural factors. Changing cultural and social pattern may modify patterns of disease. Today majority of labor force in rural community is elderly population with a concomitant increase in woman. We investigated prevalence of problems in rural population utilizing oriental medical clinic in Changsan-myon, Shinan-gun, Chunnam. The majority of patients in this area were female and in the 40 to 60s. Muscoskeletal problems had the highest incidence. Low back pain was leading complaints in the muscoskeletal problems and knee pain was the most common complaints in the digestive problems, headache in the neurologic problems. cough in the respiratory problems, hypertension in the circulatory problems, ear problems in the sense organ problems, pruritys in the dermatologic problems, leukorrhea and postmenopausal syndrome in the gynecologic problems, and dysuria and enuresis in the urinary problems. These results suggest that oriental medical physicians have attention to health care and management of the expanding population of elderly and female patients with high incidence of muscoskeietal problems in the rural community.

성균관대학교 멀티미디어 원격교육 시스템(배움 한마당) 개발에 관한 연구

김석수,권해문,이상권,김상진,전진호,황대준 成均館大學校 科學技術硏究所 1997 論文集 Vol.48 No.1

We propose SKKU Multimedia Distance Education System for distance education between nature science campus(Suwon) and social science campus(Seoul) in Sung Kyun Kwan University on DooRae (Distributed Object Oriented Multimedia Application Crafting Environment for Collaboration) framework (or platform). We support ONE : N study mode for a group lecture and discussion between two campus, and also we support mediation for floor mode of a group lecture and brain storming for floor mode of discussion. The communication portocol of this system is composed of TCP/IP and UDP, and the network type is composed of WAN(El line)for between the Suwon campus and Seoul campus, ATM LAN for each campus(local site). And, this system supports the application development of the collaborative multimedia environment connected with the various network in the CBM (Computer based Multimedia) based. Also, it does not restrict on space between a teacher(s) and a student(s) into cyberspace which made by network. This system has an interaction, late comer, a question and an answer, multi-session, application sharing and whiteboard which resembles chalkboard. Also, various supplementary functions such as video conference and voice conference for this system are what makes face-to-face education effective. Also it supports real or non-real type. The operation system developed on windows 95.

심상성 루프스에서 Nested-Primer Gene Amplification Assay에 의한 결핵균 DNA의 검출

신문석,전효진,김병천,이규석,김재룡,권호준,송준영 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Lupus vulgaris, which is a progressive form of postprimary tuberculosis in patients with a moderate to high degree of immunity and tuberculin sensitivity, is the most common, most serious, and most variable type of cutaneous and mucous membrane tuberculosis. Domonstration of M.tuberculosis directly or in culture in some of these eruptions can be difficult. It is essential to demonstrate the presence of M.tuberculosis in a clinical sample for a definitive diagnosis of tuberculosis. With the discovery of the polymerase chain reaction (PCR), the DNA diagnostic approach for infection has developed in a short period. With the dual purpose of definitive and rapid diagnosis of tuberculosis, this study examined the usefulness of a nested PCR for detection of M. turberculosis. Compared with a single-step PCR, the two-step PCR was able to enhance sensitivity approximately 1,000-fold on the basis of bacterial counts and DNA quantity. We concluded that two-step nested PCR appeared to be the most useful PCR protocol for early and sensitive diagnostic method detecting M.tuberculosis in acid-fast stain negative specimens.

두부 외상 환자의 고혈당과 예후와의 상관관계

현석천,이종안,박준석,박상문,김갑득,장인성,김승열,송화식 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Severe head injury is associated with a stress response that includes hyperglycemia, which has been shown to worse outcome during cerebral ischemia. To better define the relationship between head injury and hyperglycemia, admission glucose level were analyzed in 150 head injured patients from January 1995 to December 1995. Our retrospective study demonstrated a higher glucose level in patients with low Glasgow Coma Scale(GCS) score, especially at 3-5 GCS score, compared to those with high GCS scores. Also a higher glucose level was noted in patients with vegetative state and dead than in those with good recovery and moderate disability. Hyperglycemia(serum glucose level≥200mg%) was associated with decreased level of consciousness and a poor outcome. We conclude that admission hyperglycemia is a significant indicator of severity of injury(p<0.001), but not significant predictor outcome from head injury. After controlling for the influence of the GCS score, glucose levels do not have an independent effect on outcome.

黃酸銅溶液의 電氣傳導度에 關한 硏究

崔文錫,金仁湖,宋珍燮 慶尙大學校 1975 論文集 Vol.14 No.-

To study the electric conductivity of CuSO₄·5H₂O solution using the U. C. current, the measurements of U. C. current have been made with the changes of concentration, length of solution column and Temperature of solution. The changes of resistance, specific resistance and equivalent conductance have been researched on each condition. The follows are summarized as the results of research. (1) In the U. C. current, the equation R-R₁=ρ' l/A may he proposed to calculate the specific resistance of solution. (2) The changes of the equivalent conductance have been increased with decreasing in concentration of solution. (3) The equivalent conductance values of CuSO₄·5H₂O solution mixed with H₂SO₄ solution are larger than that of pure CuSO₄·5H₂O solution. (4) The changes of drift velocity of ions have been decreased with increasing in concentration. (5) The changes of equivalent conductance have been il]creased with increasing in temperature.

수부의 외상성 중수지 관절 탈구의 치료

이승구,송석환,이주엽,문창윤,오재찬 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목적 : 수부의 중수지 관절 탈구의 관혈적 정복이 필요했던 예에서는 정복을 방해하는 구조물에 대해 분석하고 도수 정복이 가능했던 예에서는 성별 및 탈구 형태에 따른 특성에 대해 알아보고자 하였다. 대상 및 방법 : 총 27예의 수부 중수지 관절 탁구 환자 (무지 11예, 이지 14예, 소지 2예)를 대상으로 연구하였다. 탈구된 중수지 관절의 정복을 방해하는 해부학적 구조는 수술시에 확인을 하였으며, 도수 정복이 가능하였던 예들에서도 연령과 손상된 구조물, 그리고 최종적인 임상 결과를 평균 7개월간 추시 관찰하였다. 결과 : 무지 중수지 관절의 탈구 11예 중 파열된 전방 관절낭, 수장판과 단무지 굴건의 파열을 동반한 복합 탈구가 8예 있어 관혈 정복을 시행하였으며, 2예에서만 도수 정복이 가능하였다. 관절염이 있던 1예는 관절 유합술을 시행하였다. 다른 수지의 중수지 관절의 탈구는 Kaplan의 개념에 따라 탈구를 수술 정복하였고 파열된 수장판을 복원하였으며, 1예에서 수술시 표재 중수 횡인대만의 절개와 이완으로 정복할 수 있었다. 소지 중수지 관절 탈구의 2예에서 파열된 요측 측부인대가 수술시 관찰되었고 이를 복원하여 수지의 불안정성을 예방하였다. 이들의 최종 결과는 특별한 운동 제한이나 불안정성 없이 좋은 결과를 보였다. 결론 : 적절한 국소 마취하에 도수 정복을 1~2회 시행할 수 있지만 단순 정복이 가능한 탈구가 부적절한 견인으로 정복이 불가능한 복합 탈구로 진행할 수 있다. 그리고 복합 탈구는 대부분 관혈적 정복이 필요하기 때문에, 정복 방해 구조물에 대한 충분한 이해와 적절한 조치가 필요하다. Purpose : To analyse the obstacles to prevent the reduction for dislocation of the metacarpophalangeal (MP) joints of the hand and evaluate the relationship between the sex and dislocation type in closed reduction case. Materials and Methods : Total 27 cases of MP joint dislocation of the hand (11 cases of thumb, and 14 index and 2 little finger) were reviewed retrospectively. The anatomical structures to prevent the reduction were confirmed at operation and the cases which were reduced immediately were also analysed for their ages and differences of damaged structures, and finally their complications or outcome were reviewed for average 7 months after reduction. Results : In 11 cases of thumb MP joint dislocations, the complex dorsal dislocations in which the protruded metacarpal neck was caught by buttonhole of torn anterior joint capsule, volar plate and FPB were reduced by open method in 8 cases, and closed reduction was done in 2 cases but one old case required arthrodesis. In other finger MP joint dislocations, the Kaplan's concept to prevent the reduction was confirmed. But reduction of torn volar plate and incision of transverse metacarpal ligament were sufficient to reduce the dislocation with gentle longitudinal traction during the operation. In two cases of little finger MP joint dislocation, the ruptured radial collateral ligaments were noted after open reduction and it must the repaired to prevent the finger instability later. Their overall end results were good without any significant restriction of MP joints motions and finger instabilities. Conclusion : One or two times of closed reduction with proper local anesthesia could be tried, but simple reducible dislocation can be converted to complex irreducible ones by the inappropriate traction method, and so proper reduction technique by closed or even in open way is important with the knowledge of anatomical obstacles to prevent the reduction of the metacarpophalangeal joints.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.