韓國 영유아의 蛋白칼로리 營養失調에 關한 硏究

姜英豪,金仁達 서울大學校 保健大學院 1968 公衆保健雜誌 Vol.5 No.2

A study was conducted by the author in September 1968 towards the infants and young children in some underprivileged rural villages of Korea by employing such methods as clinical assessment, nutritional biometry, and biochemical tests, in an attempt to evaluate their nutritional status with possible reference to protein calorie malnutrition (PCM). The infants and young children examined totaled 232 of whom 111 were boys and 121 were girls. The results are as follows: Ⅰ. Clinical Assessment The prevalence rates of the signs suggestive of PCM turned out to be as below : 1) Cases with dyspigmented hair were observed with 4.5% of the 45 infants examined. and 18.8% of the 187 young children examined. Cases with thin and sparse hair were seen with 22.8% of the infants, 14.0% of the young children, and l5.2% of both the infants and young children. 2) Prevalence of the pale conjunctiva rated 28.6% of the infants. 32.3% of the young children, and 30.4% of both the infants and young children. 3) Keratomalacia cases were found in 0.5% of the young children only and they corresponded, in turn, to 0.4% of the whole examined. 4) Cases with angulostomatitis rated 14.0% of the young children only, who constituted 10.0% of the total examined. 5) Those with moon-face were observed only with 2.3% of the infants, rating 0.4% of the total. 6) Cases with flaky-paint dermatosis were observed with 2.3% of the infants, 0.5% of the young children, and 0.9% of both the infants and young children. 7) Those who were found to have such skin lesions as fissure of the ear lobe, tender sores, or moist groin rash rated 15.9% of the infants, 20.4% of the young children, and 19.6% of both the infants and children. 8) Rate of those with muscles wasted was 11.4% of the infants, 25.8% of the young children, and 23.0% of both the infants and young children. 9) Those with edema were observed only with 0.5% of the young children. rating 0.4% of the total. 10) Psychomotor changes (apathetic, miserable, inert, withdrawn, or anorexic) rated 7.0% of the young children only, and 5.7% of the whole examined. 11) Prevalence rate of diarrhea precipitating dehydration and such other conditioning infections as thrush was found to be 20.5% of the infants, 7.5% of the young children, and 10.0% of both the infants and young children. 12) The results of clinical assessment led the author to the following findings: (1) Those corresponding to 29.1% of the whole examined had one or two combined signs suggestive of PCM. (2) Those with three or more signs combined rated 1.3% of the total children examined. (3) No clinically obvious kwashiorkor was found, but each of the component signs which, in constant combination, characterize it (edema, muscle-wasting, and psychomotor changes) was separately observed mainly with the young children as presented in table 2. (4) Those who impressed the author with clinically obvious nutritional marasmus were 6.7% of the infants, 3.2% of the young children, and 3.9% of both the infants and young children. Ⅱ. Nutritional Biometry 1) The mean heights. weights, chest circumference, and head circumference obtained were as shown in table 3. 2) The mean triceps skin-fold thickness, upper mid-arm-circumference. and upper-mid-arm-muscle circumference were as presented in table 4. 3) Distribution of the heights by four levels of 10% intervals indicated underweights in the light of Korean general standard, as shown in table 10. 4) Distribution of the weights contrasted likewise with the Korean general standard were as shown in table 11. 5) The underweights demonstrated by cases of mild-moderate PCM computed at four levels of 10% intervals as against the Korean general standard, rated 42.2% of the infants, 42.8% of the young children, and 42.7% of both the infants and young children. by the criteria Dr. Jelliffe suggested ??. The severe PCM cases were comprised 31.1% of the infants, 7.5% of the young children. and 12.1% of both groups of them. In the light of the above rates, more than a half of the children examined were found to be affected with PCM ascribable to deficiency of both the protein and calorie. 6) The cases with "Chest circumference/Head circumference Ratio being below 1 after the first 6 months of life" suggestive of the wasting of pectoral muscles which is attributable to PCM corresponded to 57.1% of the infants, 25.1% of the young children, and 29.3% of both the infants and young children as shown in table 13. Ⅲ. Biochemical Tests 1) Hemoglobin levels were found to be anemic (level less than 10.8gm%) with 13.8% of the 80 children examined as presented in table 5. 2) Serum total protein and serum albumin levels were as shown in tables 6 and 7, respectively. The serum albumin levels turned out to be normal with 75.9%, and "low"(2.80gm%∼3.51gm%) with 24.1% of the examined. No deficiency level (less than 2.80gm%) was found among the 29 children. 3) Serum iron content and total serum iron-bindin capacity (TIBC) were as shown in table 8. The deficiency levels of serum iron content less than 50 microgram % comprised 33.3% of the 21 children examined. Those corresponding to 25% and 75% of the 16 children examined had values of TIBC within normal range (300 microgram %∼400 microgram %) and values below the normal range (less than 300 microgram %), respectively, and no case exceeded over the range of normality inspite of the low serum iron content, suggesting the possible ascription to chronic protein deficiency ??. 4) "Urinary Urea-nitrogen / Creatinie-nitrogen excretion Ratios" regarded as an approximte index of dietary adequacy related to muscle storage of protein were obtained as presented in table 9. The cases with the ratios "30 or less" (an indication of malnutrition related to dietary adequacy of protein) rated 58.8% of the 34 children examined.

幼兒文學敎育 實態에 관한 基礎硏究 : 慶南地域 幼兒敎育機關을 中心으로

姜仁彦,金英淑 진주여자전문대학 1988 論文集 Vol.10 No.-

The purpose of this study is to examine the actual condition of the literature education of young children in Gyeong Sang Nam Do, The specific problems of this study are as follows : 1. What is the goal of young childrens's literature education? 2. What is the criteria for the selection of young children's literature books? 3. What is trends of use and interest for media of young children's literature? 1) What is trends of use and interest for fairy tales and creative tales? 2) What is trends of use and interest for picture-tales? 3) What is trends of use and interest for kinds of puppets? 4) Have you ever taken a chance of a puppet-show? 5) Have you ever taken a chance of children's drama? 6) Have you ever used the children's verse in a classroom? 4. How many books of young children's literature do they stock in kindergarten and what is the teacher s viewpoint for these? 5. How is YES or NO of the teacher s experience for a creative activity of young children's literature? 6. For fairy tales : 1) What is the title of fairy tale most used in kindergarten? 2) What is the title of fairy tale which kindergarten-boys are most interested in? 3) What is the title of fairy tale which kindergarten-girls are most interested in? 4) What is the title of fairy tale which kindergarten-teachers are most interested in? 7. What do you want in the class allocated for young children's literature in college? 8. What is the problem in young cildren's literature education? For this study 27 nursery schools, 20 kindergarten attached to elementary schools and 78 private kindergarten in Kyeong Sang Nam Do were randomly sampled. The total subject of the study were 125 teachers. The instrument used for this study was a questionnaire. It was distributed to the teachers and filled out by them. Chi-square was used to analyze by the data obtained from the questionnaire. The results of this study are as follows : 1. For the goal of young children's literature education : 'to be helped creative and expressive activities to literature in various ways' was regarded to be the most important in general. 2. For the criteria for selection of young children's literature books ; 'the contents related a unit was regarded to be the most important in general. 3. For the trends of use interest fot the media of young children s literature ; 'picture-tale' and 'picture-books' are the descending order responded. 4. For books of young children's literature and teacher s viewpoint for those ; '100 books and below them' and 101-200 books' are the descending order responded and answered 'proper' for these. 5. For the YES or No of the teacher's experience for a creative activity of youg children's literature ; 'NO' was regarded to be the most in general. 6. For fairy tales and the title of fairy tale most used in kindergartens ; 'Heungbu-Jean', 'Hokburi-younggam' and 'Hae wa Dali Deun O-nui' are the descending order responded by boys. 'Kongzui and patzui' and 'Baek-seol Princess' are the descending order responded by girls. And 'Hae wa dali Deun O-nui' and 'Hokburi-younggam' are by teachers. 7. For the request to the class allocated for young children's literature in college ; 'the manufacture technique for media of young children's literature and communiate method 'and' the guidance of the creative education to the genre of young children's literature' are the descending order responded by teachers. 8. For the problem in young children's literature education ; 'the problem of manufacture technique for media', 'The difficulty of selection for a literary work and the poor of a subject matter' and 'the poor of teaching materials' are the descending order responded by teachers.

관상동맥 스텐트 시술 후의 재협착에 관한 연구

김윤철,이정우,김보영,강정아,임대승,이민수,김정희,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

Coronary stent implacement is known as an effective treatment in the intimal dissection after percutaneous transluminal coronary angioplasty and the prevention of restenosis. However, In-stent restenosis still remains a major concern in clinical stenting. The stents were placed in 103 patients from July 1996 to March 1999 and performed follow-up coronary angiograms in 59(57.3%) patients. To identify the clinical, angiographic and procedurerelated variables 'which predict late restenosis within the stented artery, 59 patients(58.3±9.9, M:F= 41:18) were studied. The clinical characteristics of the patients were stable angina in 23(39.0%), unstable angina in 14(23.7%), acute myocardial infarction in 21(35.6%) and old myocardial infarction in 1(1.7%). Coronary stenting was performed in 1 patient(1.7%) for primary lesion, 50 patients(84.7%) for suboptimal results after PTCA, 6 patients(10.2%) for bail-out procedure, and 2 patients(3.4%) for restenotic lesions. All patients were treated with aspirin and ticlopidinc. The follow-up angiograms were obtained at 7±4 months. The overall in-stent restenosis rate was 27.1%. The coronary angiographic findings were 32 single vessel(54.2%), 19 two vessel(32.2%) and 8 three vessel disease(13.6%). The angiographic morphological characteristics were type A in 33(55.9%), type B in 14(23.7%), type C in 12(20. 3%) cases. Variables of 16 patients with restenosis were compared with those of 43 patients without restenosis. Previously known predictors for in-stent restenosis were multiple stenting, stenting for restenotic lesions, residual stenosis after stenting, stenting for total occlusion lesions, reference diameter, balloon to vessel ratio, acute gain and minimal luminal diameter after procedure, design and characteristics of stents, ostial lesion of aorta, high pressure method for stenting, lesion length, diabetes mellitus, size of artheroma, saphenous vein grafts, ulcerlating lesions and calcified lesions. In this study, Reference diameter before stenting(2.43±0.54mm vs. 2.88±0.65mm, p=0.016) and balloon-to-artery ratio(1.28±0.26 vs. 1.11±0.18, p=0.006) were predictors for in-stent restenosis. 1) The overall in-stent restenosis rate was 27.1%. 2) In the analysis of predictors for in-stent restenosis, there was no significant differences in clinical, angiographic factors between group with restenosis and without restenosis. But, Only reference diameter before stenting and balloon-toartery ratio were predictors of late in-stent restenosis. In conclusion, stenting is effective revascularisation method for selected patients with ischemic heart disease, and to minimize in-stent restenosis rate, stent implanting is achieved in a large vessel on the basis of an artery-to-stnet ration of 1:1, if possible.

Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction

( Joon Young Kim ),( Myung Ho Jeong ),( Yong Woo Choi ),( Yong Keun Ahn ),( Shung Chull Chae ),( Seung Ho Hur ),( Taek Jong Hong ),( Young Jo Kim ),( In Whan Seong ),( In Ho Chae ),( Myeong Chan Cho ) 대한내과학회 2015 The Korean Journal of Internal Medicine Vol.30 No.6

Background/Aims: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to evaluate the temporal trends and in-hospital outcomes of primary PCI in nonagenarian STEMI patients. Methods: We retrospectively reviewed data from the Korea Acute Myocardial Infarction Registry (KAMIR) from November 2005 to January 2008, and from the Korea Working Group on Myocardial Infarction (KorMI) from February 2008 to May 2010. Results: During this period, the proportion of nonagenarians among STEMI patients more than doubled (0.59% in KAMIR vs. 1.35% in KorMI), and the rate of use of primary PCI also increased (from 62.5% in KAMIR to 81.0% in KorMI). We identified 84 eligible study patients for which the overall in-hospital mortality rate was 21.4% (25.0% in KAMIR vs. 20.3% in KorMI, p = 0.919). Multivariate analysis identified two independent predictors of in-hospital mortality, namely a final Thrombolysis in Myocardial Infarction (TIMI) flow < 3 (odds ratio [OR], 13.7; 95% confidence interval [CI], 3.2 to 59.0; p < 0.001) and cardiogenic shock during hospitalization (OR, 6.7; 95% CI, 1.5 to 30.3; p = 0.013). Conclusions: The number of nonagenarian STEMI patients who have undergone primary PCI has increased. Although a final TIMI flow < 3 and cardiogenic shock are independent predictors of in-hospital mortality, primary PCI can be performed with a high success rate and an acceptable in-hospital mortality rate.

Adult invasive pneumococcal disease in the Republic of Korea: Risk medical conditions and mortality stratified by age group

Kim, Jong Hun,Baik, Seung Hee,Chun, Byung Chul,Song, Joon Young,Bae, In-Gyu,Kim, Hyo Youl,Kim, Dong-Min,Choi, Young Hwa,Choi, Won Suk,Jo, Yu Mi,Kwon, Hyun Hee,Jeong, Hye Won,Kim, Yeon-Sook,Kim, Jeong Elsevier 2018 INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Vol.74 No.-

<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>This study aimed to characterize the risk factors for mortality in adult patients with invasive pneumococcal disease (IPD) stratified by age groups, after implementation of the national immunization program of 23-valent polysaccharide vaccine (PPSV23) for those aged ≥65 years in the Republic of Korea (ROK).</P> <P><B>Methods</B></P> <P>Clinical data and pneumococcal isolates from adult patients with IPD (≥18 years of age) were collected prospectively from 20 hospitals through the nationwide surveillance program from March 2013 to October 2015.</P> <P><B>Results</B></P> <P>A total of 319 patients with IPD were enrolled. Median age was 69 years. Overall in-hospital mortality was 34.2%: 17.1% in those aged 18–49 years, 23.7% in those aged 50–64 years, 33.0% in those aged 65–74 years, and 51.0% in those aged ≥75 years (<I>p<</I> 0.001). In particular, early death within 7days of hospitalization accounted for 60.6% (66/109). While old age (≥65 years), higher Pitt bacteremia score (≥4), and bacteremic pneumonia were independently associated with IPD mortality in all age groups, an additional mortality risk factor of immunocompromised status was identified for patients aged 50–64 years. PPSV23 serotypes accounted for 64.4% (122/189) of the pneumococcal isolates serotyped.</P> <P><B>Conclusions</B></P> <P>This study suggests that vaccine-type IPD continues to place a substantial burden on older adults in the ROK, necessitating an effective vaccination strategy for those at higher risk.</P> <P><B>Highlights</B></P> <P> <UL> <LI> National immunization of the elderly with the 23-valent polysaccharide vaccine (PPSV23) was implemented in Korea in 2013. </LI> <LI> Overall in-hospital mortality was 34.2% for adult invasive pneumococcal disease (IPD) and 51.0% for patients ≥75 years of age. </LI> <LI> Mortality risks were older age, higher bacteremia score, and immunocompromised status. </LI> <LI> An effective vaccination strategy for those at higher risk of IPD is needed. </LI> </UL> </P>

의료방사선관리의 국제화 연구 : 핵의학분야의 의료방사선관리

김인규,오헌진,김혁주,오현주,박기정,이광용,이병영,정승환,강영규,이현구,김귀야,한상용,김연교,양현규,이명철 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

의료방사선은 인간의 질병진료와 예밤에 활용되어 각종 질병으로부터의 적절한 진단 및 의학발전에 중대한 역할을 담당하고 띤다. 또한 인공방사선원중 가장 큰 비중을 차지하고 있으며, 방사선원을 이웅한 이득과 손실을 생각쌀 때 피폭선량의 최소화 및 곡률적영향의 최소화를 위해 이득을 최대화하는 노력을 하고 있다. 진단뿐만 아니라 치료에도 사응하고 있는 인공방사선원의 적절한 관리를 위한 조사 및 연구는 국내에서는 아픽까진 실시되지 않았으며, 국외에서는 이미 활발한 조사 덴 연구가 이루어 지 고 있다. 일반적으로 의료기관의 핵의학분야에서 환자의 진단 및 치료에 사용되는 방사성의약품으로는 Tc-99in, Ga-67, 1-131, 71-201 등이 있으며 이를 이용한 방사능측정웅장비 및 치료뭉장비에는 Gamma Camera, 감마선재측기, 베타선계측기, Dose CaTibrator, PET(양전자방출전산화단층촬영장치)등이 있다. 이어 식푿의약품안전청f"서는 핵의학분야의 방사선보건학적 연구를 위해 핵의학분야의 진료와 관련된 인력, 시설, 장비, 방사성의약품의 사응, 핵의학적 진료형태 및 핵의학적 진료장치에 대한 성능관리등에 대해 조사·연구하였다. A nationwide survey was conducted in the Korea in 2001 to determine the facilities available and the level of activity at centres where radionuclide and therapy was practised in 2000. A response rate of 75% indicated that 120 centres were providing radionuclide therapy and diagnosis. About the good treatment of radionuclide using in medical, researched so many country, but not yet in. Generally nuclear medical part use Tc-99m, Ga-67, I-131, Tl-201 in diagnosis and therapy, radiation detector and equipment for therapy use Gamma Camera, beta-counter, Dose Calibrator PET(Positron Emission Tomography). 81% rate of centre has Gamma Camera and 97% rate of use Tc-99m, I-131 radionuclide. In-vitro did more than in-vivo test absolutely. So in KFDA researched in unclear medical part in Man-Power, facilities, equipment use of nuclear medicine, part of diagnosis and diagnosis equipment.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

유치 및 초기 영구치아의 치수 신경분포

김영진,남순현,김현정,이재문,이인정 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2

유치 및 초기 영구치의 치수신경분포 및 변화를 평가하기 위하여 교정치료를 위해 발치한 치근흡수가 비교적 적은 유치,정상 탈락기의 유치,맹출중인 교합하지 않은 제 1소구치,맹출이 완료되어 교합하고 있는 1소구치를 대상으로 neurofilament protein(NEP)을 이용한 면역조직화학적 방법으로 관찰하여 다음과 같은 결과를 얻었다. 치근흡수가 비교적 적은 유치에서도 영구치와 유사한 신경총의 존재와 신경분포 형태가 관찰되었으나,영구치에 비해 그 신경분포 밀도가 낮았으며 분지형성 또한 미약하게 나타났고,전상아질로 진입하는 섬유의 수가 적었다. 정상탈락기의 유치에서는 신경의 변성으로 소포(vesicle),단절(fragmentation)등이 관찰되었으며,그 신경분포가 현저히 감소되어 나타났고,총상의 형태도 소실되었다. 교합하지 않은 제 1소구치에서 치수내의 신경은 말단가지의 숫자가 적고,치수 조상아 세포 경계에 도달하였으며,비교적 가는 신경 섬유가 많았다. 교합하고 있는 제 1소구치에서 치수내의 신경은 말단이 조상아층으로 진출하고,어떤 신경섬유는 전상아질층까지 진입하였으며,비교적 굵은신경 섬유의 분포가 많아졌다. The purpose of this study was to investigate the distribution of nerves in the dental pulp of early extracted primary teeth,normal exfoliated teeth,partially-erupted,nonfunctional,premolars,and erupted,functional,premolars.Numbers of sample were 10 teeth in each group. The distribution of nerves in the dental pulp were investigated by means of immunohistochemistry for detection of neurofilament protein(NFP). The results were as follows: The early extracted primary teeth exhibited patterns of innervation similar to those observed for young permanent teeth.The plexiform arrangement of fibers was not evident in the primary teeth.Most nerves appear to terminate about the odontoblasts. As primary teeth began to undergo root resorption,degenerative changes such as vesicles and fragmentation appear in nerves.The quantity of neural tissue also decreased.In teeth in which the roots were almost completely resorbed only a small number of nerves remain. There was a decrease in the number of terminal branches in the pulp of the partiallyerupted,nonfunctional,premolars and those present reached the pulpo-odontoblastic border. The nerve terminals in the pulp of the erupted,functional,premolars were traced to the dentinal tubule and a few nerve fibers formed loops in the predentin.

성인 IgA 신병증의 임상적 고찰

김영학,권용은,허경무,윤채중,김종인,김건영,배학연,정종훈 조선의대 1998 The Medical Journal of Chosun University Vol.23 No.1

干拓地의 農業開發을 위한 綜合硏究 : IV.界火島 干拓地의 土壤微小動物相에 관한 연구 -

金泰興,蘇仁永,郭晙洙,金俊範 전북대학교 농업과학기술연구소 1987 農大論文集 Vol.18 No.-

This study was carried out to investigate the soil arthropods and nematodes fauna, population density, biomass, vertical distribution, seasonal fluctuation , and the relationship between the density of soil inhabiting animals and some edaphic factors such as organic matter , pH, temperature, moisture, and salt concentration at reclaimed paddies Samples were taken on January 25, April 5, July 9, and October 4 in1986 from three sites of Gyehwado reclaimed land and one paddy field of Ch?nmidong ,n Ch?n Buk province, southern part of Korea. The results were as follows : 1. Soil arthropods consisted of Diptera (41 .2% ), Collembola(36%), Acarina(21.1%). and etc .. but the proportion in biomass of Diptera(90.5%) showed the highest of all, Nematodes fauna was composed of free living type(55.7 %), p.edato.5(33.') %), and plant parasites(11 .1 %). 2. Density and biomass of arthropods were highest In Ch?nmldong site(35.4 %), and of nematodes highest in the Gyehwa Ⅲ slte. 3. Arthropods(83.4%) and nematodes(65%) were found the most In the first layer. subsoil, i.e., 0-5in and 0-10 in, respectively but the density of arthropods was higher than that of nematodes 4. The population density of arthropods showed highest in April lowest In July, slightly increasing in October. And of the nematodes showed highest in October, lowest in January. 5. Density of arthropods In the first layer decreased gradually from January to July, and slightly increased in October. Of the nematodes. the highest In July and the lowest in April. 6. The correlations between arthropods and organic matter, pH, and temperature were significant , respectively but those of nematodes were significant In case of temperature only.