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      • KCI등재

        일반논문 : 낙오자와 영원인 -서정주의 신라 기획과 전율의 시학-

        정영진 ( Young Jin Jeong ) 반교어문학회 2015 泮橋語文硏究 Vol.0 No.41

        서정주는 당대의 허무주의를 현대 서구문명의 병폐로 이해했으며 신라정신을 통해 이 문제를 극복하고자 했다. 이 글에서는 우선 서정주의 신라정신이 그가 상상한 신라 사회에서 어떤 방식으로 기능하고 있었는지 살펴봄으로써, 서정주의 신라 기획이 사회문화적 가치체계로서 제안된 것이었음을 보여주고자 한다. 서정주가 상상한 신라 사회는 현실규범과 현실논리에서 낙오한 이들이 영원성의 세계 속에서 재생할 수 있도록 허용하는 사회였다. 이 ‘낙오자’들은 비록 현실로 복귀할 수 없지만 영원성의 세계에 거주하면서, 신라인들에게 영원성의 세계를 현시한다. 즉, 그의 신라 기획은 사회통합적 성격을 내포하는 것이었다. 그러나 서정주의 시에는 이러한 신라사회의 모습이 전혀 드러나지 않는다. 뿐만 아니라 서정주는 서구정신과 신라정신의 대립이나, 현실세계와 영원성의 세계의 관계 역시 시에서 다루지 않는다. 그의 시에서 신라의 ‘영원인’들은 현실사회에서의 낙오자의 성격이 삭제된 채, 사랑의 주체로 나타난다. 이들은 다만 새로운 앎과 감동을 소유하고 절대적 세계를 현시한다. 즉, 신라 기획의 일부만이 시에 바쳐졌다고 할 수 있는데 이는 서정주의 시인식에 따른 결과이다. 서정주는 현대시가 ‘전격적 쇼크’ 혹은 ‘전율’로 체험되어야 한다고 생각했기 때문에, 신라 기획의 사상적 성격을 모두 제거하고, 불사(不死)의 이미지로 전형화 된 영원성의 세계만을 시화(詩化)했다. 불사의 이미지들은 현실 전부를 점유해버리는 현실초과의 성격을 띠는데 이로 인해 그것은 영원성으로 감각된다. 다시 말하면 현실에서의 절대성이 영원성으로 치환되고 있는 것이다. 서정주 시(중기시)의 개성(스타일)의 확립은 신라정신이라는 보편적 사상 기획에 근거한 것이기는 했지만, 동시에 순수시에 대한 신념과 현대사회에서의 시의 효과에 대한 그의 시인식에 따라 신라 기획의 일부만을 미학화 한 결과였다. Seo Jeong-ju understood nihilism at the time as a social ill of modern western civilization, and sought to overcome this problem through the Silla spirit. This article seeks to show that the Silla planning of Seo Jeong-ju was suggested as a sociocultural value system by examining how Seo Jeong-ju`s Silla spirit was functioning in the Silla society he imagined. The Silla that Seo Jeong-ju imagined was a society allowing those who failed in terms of the norms of reality and logic of reality to be born again within the world of eternity. Although these losers may not return to reality, they could show the world of eternity to the people of Silla, while residing in the world of eternity. Seo Jeong-ju`s Silla planning implied a character of social integration. However, Seo Jeong-ju`s poetry do not reveal such features of the Silla society at all. Not only that, Seo Jeong-ju does not deal with the conflict between the western spirit and Silla spirit and the relationship between the world of reality and world of eternity in his poetry. The ‘people of eternity’ of Silla appear as the main agents of love in his poetry, and these agents display an absolute world and possession of new knowledge and impression. Thus, in other words, only a part of the Silla planning has been dedicated to his poetry, which is a result of Seo Jeong-ju`s cognition on poetry. Because Seo Jeong-ju believed that modern poetry must be experienced through ‘lightning shock’ or ‘thrill’, he removed all ideological characters of Silla planning, and only treated the world of eternity, which was embodied through the image of immortality, in poetry. The establishment of personal characteristics (style) of Seo Jeong-ju`s poetry (middle-period poetry) was based on the planning of a universal idea called Silla spirit, however, was also a result of treating only a part of the Silla planning aesthetically based on his cognition on poetry, concerning the effect of poetry in modern society and his principle on pure poetry.

      • KCI등재

        민성휘(閔聖徽) 가문의 장서 연구 -7대손 민경속(閔景涑)과 유만주(兪晩柱)의 서적 왕래를 겸하여-

        김영진 ( Kim Young-jin ),안정은 ( Ahn Jeong-eun ) 한국한문학회 2020 韓國漢文學硏究 Vol.0 No.80

        본고는 조선시대 서책문화, 그 가운데 ‘私家藏書’에 대한 사례 연구를 여흥민씨 閔聖徽(1582~1648) 가문을 대상으로 한 것이다. 연구의 주안점은 두 가지인데 첫째는 민성휘 개인이 본격적으로 형성한 ‘사가장서’의 실체와 특징이고, 둘째는 민성휘의 7대손 閔景涑(1751~1794)의 장서다. 후자의 경우엔 벗 兪晩柱(1755~1788)와의 사이에 이루어진 書冊 相互 借覽과 문학, 학술 담론을 중심에 두었다. 민성휘의 1628년 明 使行에서의 서책 구입과 민경속과 유만주의 교유는 기존 연구성과가 있다. 본고는 기존 성과 위에 민성휘 윗대 아랫대의 저술 및 장서 현황, 소론 당파보인 『簪譜』 및 민경속의 인척 鄭堉이 편찬한 印譜 『圖書譜』, 任天常의 『試筆』 등의 신자료를 추가하여 이 가문의 장서 형성 과정과 그 학술 문화사적 특성을 보다 구체화하였다. 우선 민성휘의 『肅敏書目』을 재검토하고 현존하는 민성휘 장서인이 압인된 책들을 조사하여 관련 방증을 하였다. 또한 민성휘가 수집한 장서와 서책에 대한 관심이 가까이는 민성휘의 『松京訪碑錄』, 閔晉亮의 『唐詩類選』, 閔周冕의 『(新纂)東京誌』로 이어졌고, 멀리는 7세손 민경속의 『知先錄』과 『迂叟謾錄』 및 『輸廫故人錄』, 8세손 閔魯行의 『名數咫聞』과 『咫聞別集』 등으로 이어졌음을 논하였다. 민경속과 유만주 사이에 1785년부터 1787년까지 3년간 지속된 서책 교류를 총정리하였다. 이 둘의 진지하고 진솔한 학술교류는 방문 외에 양가 장서 및 서화의 상호 대차와 감상을 기본으로 하였는 바 두 가문의 당파와 교유권의 차이로 인해 수장 자료의 성격차이 역시 컸다. 이 점이 상대방의 호기심을 일으키고, 부족한 면을 충족시켜 주면서 서로의 성장에 밑거름이 되었다. 민경속의 인척으로 특히 주목되는 것이 ‘江華學’으로 널리 알려진 전주이씨 덕천군파와 연일정씨 鄭夏彦 후손가다. 연일정씨는 또 자하 신위와 연결되어 이후 민노행이 추사 김정희와 교류를 갖게되는 계기가 되었다. 민성휘가의 『서책목록』이 발견되지 않았고, 이 가문의 장서도 다 흩어졌다는 제약과 한계 속에서도 여러 자료의 편린들을 찾아내어 민씨가의 학술문화사적 의의를 추출하여 보았다. 이 과정에서 兪晩柱의 『欽英』이 갖는 서적문화사에서의 높은 의의를 재삼 확인할 수 있었다. 여흥민씨가의 장서와 그것의 학술문화사적 효용은 ‘조선시대 사가장서’의 한 실상과 의미 부여를 하였다는 데에 의의가 있다 하겠다. This thesis focused on the book culture in the Choseon Dinasty period, particularly with the emphasis laid on the family of the Yeoheung Mins by way of the case study on the collection of books at the private family of Seong-Hui Min(1582~1648) of the Yeoheung Mins. The main emphasis is two and the first is the substance and characteristics of ‘the collection of books at private family’ purposefully formulated by the individual Seong-Hui Min and the other is the collection of books of the 7<sup>th</sup> descendant Gyeong-Sok Min(1751~1794). In the latter case, the focus was laid on the mutual borrowing and reading of the books and academic discourse with his friend Man-Ju Yoo(1755~1788). The purchase of books by Seong- Hui Min in his envoy trip to Ming in 1627 and the exchange between Gyeong-Sok Min and Man-Ju Yoo were greatly facilitated by Ha-Ra Kim. On top of the achievements of Ha-Ra Kim, this thesis carried out a more realistic review of the background of the formulation of the collection of books at this family and the academic and cultural historical characteristics with reference to the significant new data such as the writings and the status of book collections, the newsletter of Soron Party 『Jambo』, the book of impressions of seals 『Doseobo』 published by Yook Jeong who was a member of Yeonil Jeongs which was a relative family of Gyeong-Sok Min and others. First, this thesis aimed to establish the circumstantial evidence by conducting a review of 『Sukminseomok』 written by Seong-Hui Min and investigating the books belonging to the extant collection of books of Seong-Hui Min. It was verified that most of the pressing books from the extant collection of Seong-Hui Min are wood-block print books from Ming and discussed that the books were scattered from early stages. In addition, it was discussed that the attention to the collections and books established by Seong-Hui Min extended closely to 『Songgyeongbangbirok』 by Seong- Hui Min, 『Dangsiyuseon』 by Jin-Yang Min and 『(New Publication) Donggyeongji』 and remotely to 『Jiseonrok』, 『Osumyeonrok』 and 『Suyogoinrok』 by the 7<sup>th</sup> descendant Grong-Sok Min and 『Myeongsuchimun』 and 『Jimoonbyeoljib』 by the 8th descendant No-Haeng Min. The thesis made an aggregate summary of the exchange of books between Gyeong-Sok Min and Man-Ju Yoo which lasted for 3 years from 1785 to 1787. The earnest and sincere academic exchange between them revealed the differences in the books and paintings stored due to the differences in faction, relatives and others apart from the collection of books in each family and these differences made great contribution to their mutual growth by invoking the intellectual curiosity and supplementing the deficient parts of each. The books of Gyeong-Sok Min can be divided between those inherited and those collected by oneself and in regard of the latter it was confirmed that the relative share of the books from Choseon Dynasty was much increased and that the relative families the Jeonju Lees (Deokcheongun family branch - Ganghwahak) and the Yeonil Jeongs inflicted a great influence on the procurement of books. By way of the connection with Jaha Wui Shin, the Yeonil Jeongs offered the opportunity for No-Haeng Min to have exchanges with Chusa Jeong-Hee Kim. Even under the limitation and restriction that 『List of Books』 of the family of Seong-Hui Min was not discovered and the collection of books of the family was all scattered around, the academic and cultural historical implications of the books of the Mins was extracted by discovering the partial fractions of a diversity of data. In this process, the high cultural historical value of the literatures retained by 『Heumyeong』 by Man-Ju Yoo could be ascertained anew. This thesis has the meaning that it highlighted the fact that the collection of books at the Yeoheung Mins and their academic and cultural historical utility reveal a realistic aspect of the ‘collection of books at private families in Choseon Dynasty Period’ and also that it gave such a meaning.

      • 혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

        임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

      • SCOPUSKCI등재

        Dimethylnitrosamine 유발 급성 간 손상 흰쥐에서 ^(99m)Tc-Lactosylated Serum Albumin을 이용한 간 기능의 평가

        정신영,이재태,서명랑,유정아,배진호,안병철,황재석,정재민,하정희,이규보 대한핵의학회 2003 핵의학 분자영상 Vol.37 No.6

        목적: ^(99m)Tc-lactosylated serum albumin (^(99m)Tc-LSA)은 간세포에 특이적으로 결합하는 간수용체 영상용 방사성의약품으로 새로이 합성되었다. 간섬유화를 유발하는 dimethylnitrosamine (DMN)을 투여한 간 손상 휜쥐 모델에서 ^(99m)Tc-LSa의 역동학적인 간섭취를 조사하고 간효소치의 변화와 조직학적 소견을 비교하여, LSA의 간섭취가 간기능의 변화를 반영하는지를 연구하였다. 대상 및 방법: SD계 흰쥐에 DMN를 27 mg/kg으로 복강 내 주사하여 급성 간손상을 유도하고 대조군과 비교하였다. DMN을 주사한 흰쥐를 3일(DMN-3), 8일(DMN-8), 21일(DMN-21)에 ^(99m)Tc=LSA (1,665 mg/kg) 29 MBq를 정맥 주사하여, 30분 동안 동적 영상을 획득하고 간과 신장부위에 관심영역을 설정하여 간과 심장부위의 시간방사능 곡선을 얻었다. 간기능 평가를 위해 시간방사능 곡선을 이용하여 간섭취지수와 혈중제거지수를 구하였고 곡선 최적화를 시행하였다. DMN 투여군과 대조군의 간효소치의 변화와 간조직의 광학현미경 소견을 비교하였다. 결과: 대조군에서는 ^(99m)Tc-LSA가 빠르게 간에 섭취되고 혈중에서 제거되었으나 DMN을 처리한 군에서는 간섭취가 낮았다. 간섭취지수의 비교에서 대조군에 비해 DMN 처리군에서 유의하게 간섭취지수가 낮았다(DMN-3: 0.842, DMN-8: 0.898, DMN-21: 0.91, 대조군: 0.96, p<0.05). 혈중제거지수의 비교에서도 대조군에 비해 DMN 처리군에서 혈중제거지수가 유의하게 높았다(DMN-3: 0.731, DMN-8: 0.654, DMN-21: 0.604, 대조군: 0.473, p<0.05). 비선형 회귀분석에서 R_(2) 값은 0.9이상으로 좋은 일치를 보였고, 대조군에ㅓ K값이 DMN처리군에 비해 크고(DMN-3: 0.28, DMN-8: 0.41, DMN-21: 0.46, 대조군: 0.97, p<0.05), T_(1/2)값은 작았다(DMN-3: 2.5, DMN-8: 1.7, DMN-21: 1.5, 대조군: 0.7, p<0.05). 간효소치의 변화는 DMN-3군에서는 대조군에 비해 상승하였으나 DMN-8, DMN-21군에서는 간효소치의 상승이 관찰되지 않았다. 간조직 소견의 경우 DMN-3군에서 중심정맥 주위에 괴사가 관찰되었으나 DMN-8군, DMN-21군에서는 미약한 정도의 염증세포 침윤만이 관찰되었다. 결론: ^(99m)Tc-LSA 간신티그래피의 간섭취 정도는 간손상과 반비례하였으며 간섭취의 변화는 조직학적 손상이 심한 정도와 간손상후 회복되는 과정을 반영하여 주었다. ^(99m)Tc-LSA 간신티그래피가 간손상을 평가하고 간손상후 회복되는 과정을 추적하는 간수용체 영상용 방사성 의약품으로 사용될 수 있을 것으로 생각된다. Objects: ^(99m)Tc-lactosylated human serum albumin(LSA) is a newly synthesized radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically presented on the hepatocyte membrane. Hepatic uptake and blood clearance of LSA were evaluated in rat with acute hepatic injury induced by dimethylnitrosamine(DMN) and results were compared with corresponding findings of liver enzyme profile and these of histologic changes. Materials and Methods: DMN (27 mg/kg) was injected intraperitoneally in Sprague-Dawley rat to induce acute hepatic injury. At 3(DMN-3), 8(DMN-8), and 21(DMN-21) days after injection of DMN, LSA injected intravenously, and dynamic images of the liver and heart were recorded for 30 minutes. Time-activity curves of the heart and liver were generated from regions of interest drawn over liver and heart area. Degree of hepatic uptake and blood clearance of LSA were evaluated with visual interpretation and semiquantitative analysis using parameters (receptor index : LHL3 and index of blood clearance : HH3), analysis of time-activity curve was also performed with curve fitting using Prism program. Results: Visual assessment of LSA images revealed decreased hepatic uptake in DMN treated rat, compared to control group. In semiquantitative analysis, LHL3 was significantly lower in DMN treated rat group than control rat group (DMN-3:0.842, DMN-8: 0.898, DMN-21: 0.91, Control: 0.96, p<0.05), whereas HH3 was significantly higher than control rat group (DMN-3: 0.731, DMN-8: 0.654, DMN-21: 0.604, Control: 0.473, p<0.05). AST and ALT were significantly higher in DMN-3 group than those of control group. Centrilobular necrosis and infiltration of inflammatory cells were most prominent in DMN-3 group, and were decreased over time. Conclusion: The degree of hepatic uptake of LSA was inversely correlated with liver transaminase and degree of histologic liver injury in rat with acute hepatic injury.

      • KCI등재

        Soft, adhesive and conductive composite for electroencephalogram signal quality improvement

        Jeong E Jin,Seohyeon Kim,Hyeji Yu,Keyong Nam Lee,Young Rag Do,Seung Min Lee 대한의용생체공학회 2023 Biomedical Engineering Letters (BMEL) Vol.13 No.3

        Since electroencephalogram (EEG) is a very small electrical signal from the brain, it is very vulnerable to external noise ormotion artifact, making it difficult to measure. Therefore, despite the excellent convenience of dry electrodes, wet electrodeshave been used. To solve this problem, self-adhesive and conductive composites using carbon nanotubes (CNTs) in adhesivepolydimethylsiloxane (aPDMS), which can have the advantages of both dry and wet electrodes, have been developed bymixing them uniformly with methyl group-terminated PDMS. The CNT/aPDMS composite has a low Young's modulus,penetrates the skin well, has a high contact area, and excellent adhesion and conductivity, so the signal quality is enhanced. As a result of the EEG measurement test, although it was a dry electrode, results comparable to those of a wet electrode wereobtained in terms of impedance and motion noise. It also shows excellent biocompatibility in a human fibroblast cell test anda week-long skin reaction test, so it can measure EEG with high signal quality for a long period of time.

      • 모체 Thyroxine 투여가 태아알코올효과를 가진 흰쥐 대뇌겉질 및 해마에서 NPY함유 신경세포의 생후 발달에 미치는 영향

        김복,박상기,박영란,김종중,문정석,김주수,문영민,현영식,천관영,정윤영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

        Background and Objectives: Maternal alcohol abuse is considered to be one of the most prominent cause of neurobiological malformations in the postnatal and adult life of the offspring. In this study, we investigated the effects of maternal alcohol drinking on the postnatal development of NPY-containing neuron, and, the influence of thyroxine treatment on the cerebral cortex and hippocampus of pups of alcohol abused mother. Materials and Method: Time-pregnant rats were divided into three groups. Alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day 6; control pair-fed group B was fed a liquid diet in dextrin replaced alcohol isocalorically: alcohol + T4 group C received 35 calories liquid alcohol diet and exogenous thyroxine subcutaneously. Results: Group C showed prominent NPY immunoreactivity in the cerebral cortex compared to group A and B at P7. In group C, NPY-containing neurons were widely distributed in the all layers of cerebral cortex after P14. Besides, numerical decrease of NPY-containing neuron as age increases was not found in group C. However, the decrease of NPY-containing neuron was clearly observed in group A compared to group C after P14. In hippocampus, group Band C were appeared similar patterns after P7. Additionally, in group C, NPY immunoreactivity was prominently appeared in CA2 and CA3 at P14 as compared to group B. Conclusions: The present results showed the increase of intensity and number of NPY-containing neurons in cerebral cortex and hippocampus of pups of exogenous T₄ supplemented alcohol-exposed dams as compared to control pair-fed and alcohol-exposed pups at P7. It presumably suggest that NPY-containing neurons might be regulated by the early postnatal growth stimulatory effect of the exogenously supplemented T₄. Therefore, the increase of NPY synthesis caused by maternal administration of exogenous thyroxine may ameliorate fetal alcohol effect, one of the ill effects as a result of the dysthyroid state following maternal alcohol abuse.

      • 폐경후 골다공증 환자에서 체질량지수에 따른 Alendronate의 효과

        조영석,나소영,이효진,홍우정,김군순,김도희,구본정,송민호,김영건,노흥규 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

        배경 : 폐경후 골다공증은 심각한 문제로 대두되고 있다. 현재 Alendronate는 폐경후 골다공증의 치료제로서 널리 쓰이고 있다. 저자는 Alendronate의 골밀도에 효과를 알아보고 골다공증의 위험인자에 따른 Alendronate의 반응 정도를 평가하기 위하여 본 연구를 수행하였다. 방법 : Alendronate를 평균 12개월간 복용한 35명의 폐경후 골다공증환자에서 체질량지수와 폐경후 기간에 따른 치료효과를 조사하였다. 결과 : 전체 대상군에서 Alendronate 10㎎을 12개월간 투여한후 골밀도의 평균 변화율은 요추와 대퇴골 경부에서 각각 7.83±7.39%와 2.99±9.22%이었다. 과체중군에서 평균변화율은 요추와 대퇴골 경부에서 각각 7.15±4.5%와 3.05±2.86%였다. 양군간에 통계적 유의성이 있는 차이는 없었다. 폐경후 7년이 경과되지 않은 군에서의 평균변화율은 요추와 대퇴골 경부에서 각각 6.9±5.3%와 5.71±0.08%였다. 양군간에 통계적인 유의성이 있는 차이는 없었다. 결론 : 마른체형이 골다공증의 발병에는 영향이 있으나, Alendronate 치료효과의 차이는 없는 것을 확인할 수 있었다. 더불어 폐경이 있고 7년이 초과된 군과 년이 경과되지 않은 군에서의 Alendronate 치료효과의 차이는 없는 것을 확인할수 있었다. 이는 골흡수가 상당히 진행된 상태에서도 Alendronate가 치료효과를 가지고 있음을 반영한다고 할 수 있겠다. Postmenopausal osteoporosis is a serious health problem. The aminophosphonate Alendronate is widely used for treatment of postmenopausal osteoporosis. We studied the effect of l0㎎ of alendronate given daily for mean 12 months on bone mineral density in 35 women(mean age 61yrs. mean BMI 23.24㎏/m^(2)) with osteoporosis. An over weight group is defined such that BMI was above 23㎏/m^(2). All the women received 1500㎎ calcium carbonate daily. The bone mineral density of L-spine and femoral neck was measured by dual-energy X-ray absorptiometry. Alendronate increased BMD at mean 12 months at the L-spine (7.15±4.5%) and femoral neck(3.05±2.86%) in normal women. Alendronate increased bone mineral density at 12 months at the L-spine(6.00±5.3%) and femoral neck(4.17±4.87%) in overweight women. There was no difference between two groups. In the less than 7 years group of postmenopausal duration. alendronate increased bone mineral density at 12 months at the L-spine(6.9±4.9%) and femoral neck(3.18±7.1%). In the more than 7 years group of postmenopausal duration, alendronate increased hone mineral density at 1% months at the L-spine(6.5±5.3%) and femoral neck(5.71±0.08%). There was no difference between two groups. In postmenopausal women with osteoporosis, therapy with alendronate produced significant increases in BMD of the L-spine and femoral neck in both group. There was no difference between normal and over-weight groups. and between less than 7 years group and more than 7 years group of postmenopausal duration.

      • 급성충수돌기염으로 발현된 방선균증 2예

        조진원,송진영,김창억,민영훈,최창순,우흥정,현인규,김종현,유기철,채승완,손진희 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

        The Actinomyces species are normal flora of oral cavity and upper intestine characterized as gram-positive, non-spore-forming anaerobic or mjcroaerophilic rods. Actinomycosis is a chronic suppurative and granulomatous disease characterized by abscess, sinus, abundant granulation and mass. The appendix is the commonly involved site among abdominal actinomycosis. Abdominal actinomycosis is often difficult to diagnose before operation because of no reliable clinical features and infrequency of the disease. We report two cases of abdominal actinomycosis which were manifested as acute appendicitis. Those were detected Incidentally tv the pathologist after routine appendectomy. Both patients were successfully treated with appendectomy followed by proper antibiotics use.

      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

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