서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

Mesh형 내부전극을 사용한 2중 원통형 오존발생기의 온도 의존특성

전병준,이상근,송현직,박원주,이광식 영남대학교 공업기술연구소 1999 工業技術硏究所論文集 Vol.27 No.1

Nowadays, environment pollution caused by development of industrial society becomes a serious social problem. So, ozonized gas is suggested as a counter plan against the problem. In this paper, a double cylindrical type ozonizer has been designed and manufactured to improve ozone yield by cooling external electrode. The ozonizer equipped with three electrodes(central, internal and external electrodes) and two gaps. Discharge and ozone characteristics are described in this paper by varying flow rate( Q ) of oxygen suppling gas, temperature of cooling gas and supplied voltage.

성형조건에 따른 무연탄계 활성탄의 세공특성

이송우,나영수,김도한,류동춘,최동훈,류병순,송승구 한국화학공학회 2002 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.40 No.1

본 연구는 무연탄으로 활성탄을 제조할 경우 성형이 세공특성에 미치는 효과를 고찰한 것이다. 3가지 다른 방법으로 활성탄(파쇄형 활성탄, 압축성형 활성탄, 압축성형 활성탄)을 제조하여 특성을 비교했다. 이중에서 25%의 콜타르와 7%의 물을 혼합하여 압출 성형한 활성탄이 비표면적, 세공부피, 그리고 경도에서 가장 좋은 물성을 나타내었다. 압축 및 압출 성형체의 표면은 무연탄 원탄과는 달리 무연탄 분말이 바인더와 혼합되어 있으므로 매우 거친 상태를 나타내었고, 활성화시 거칠게 형성되어 있는 입자사이로 활성화제인 수증기가 쉽게 침투하여 많은 세공을 형성시킴을 알 수 있었다. 이렇게 형성된 세공을 통해 수증기 활성화반응이 잘 일어나 직경 3,000-50,000Å 범위의 거대세공이 발달하였다. 파쇄형 활성탄에 비해 약 2배의 거대세공(macropore)부피를 가지고 있었으며 경도도 30%에서 95% 이상으로 상승되었다. This study was to investigate the effect of granulation process on pore characteristics in manufacturing anthracitebased activated carbons. The activated carbons were made by three different methods to compare characteristics: the crushed activated carbon, the compressed activated carbon, and the extruded activated carbon. Among these activated carbons, the extruded activated carbon using a binder that consists of 25% coal tar and 7% water showed the best characteristics in specific surface area, pore volume, and hardness. Since the compressed and the extruded substances had coarser surfaces than a raw material, steam could penetrate easily through particles and produce macropores especially in the diameter ranges of 3,000-50,000Å during activation process. The extruded activated carbon showed about twice more macropore volumes than the crushed activated carbon and the hardness was increased from 30% up to 95%.

용지 호수공원의 수질관리 방안에 관한 연구

이춘수,서규태,문병현,이택순 7개 국립대학교 환경연구 논문집 공동발행 위원회 2003 공업기술연구 Vol.3 No.-

This study was performed for water quality management of Yonggi Lake Park in Changwon City. The results are as follows; The water quality of the lake was deteriorated during summer season because of algal blooming. It was estimated that existing treatment capacity of the lake water was not sufficient to meet the target lake water quality. And so the lake water circulation period, 40 days should be shorten to below 30 days by increasing the treatment capacity. Fountain and air supply facilities for 02 supply and mixing caused rather resuspension of solid settled at the bottom of the lake. It was also evident that the extended detention of water in the lake resulted in water quality deterioration. Consequently it is important to supply high quality water from other sources. Especially lower temperature water had better effect on improvement of the water quality.

사람唾液 Superoxide Dismutase의 精製 및 性狀

이봉재,이병래,전현우,양종대,이근배 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1

The purification and some properties of superoxide dismutase(O_(2-)-O_(2-) oxidoreductase, ECI. 15.1.1) of human saliva have been studied. Human saliva was collected from medical students, male and female together with smoking male students. The activity of superoxide dismutase was measured by the method of McCord and Fridovich. The superoxide dismutase was purified by ammonium sulfate precifitation, DEAE-cellulose and sephadex C-100 column chromatography. The results are summerized as follows : 1. Human saliva contain measurable amounts of superoxide dismutase. 2. The activities of superoxide dismutase. were 0.72U/㎖ in male and 0.73U/㎖ in female saliva. The activity of this enzyme was 0.81U/㎖ in smoker. Accodingly, there was no recognizabIe differences in the enzyme activity between smoker and non-smoker. 4. The human salivary superoxide dismutase was purified approximately 90 folds, and the molecular weight of the purified enzyme was estimated to be approximately 32,000 by gel filtretion. 4. Purified salivary superoxide dismutase has contained 1.83 atoms of copper and 2.00 atoms of zinc per molecule and was strikingly similar to the superoxide dismutase previonsly isolated from other cukaryotes by other investigatury. 5. The ultraviolet absorption spectrum of purified salivan- superoxide dismutase was 268㎚ which was similar to the value previously seen with the cytosolic enzyme of eukaryotes.

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

임플란트 식립을 위한 상악동 점막 거상술의 결과

천상득,정보연,이승은,윤홍식,진병로 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.2

Background: Although dental implantation has become widespread and acceptable treatment for dental prosthodontics, maxillary posterior jaw region is often complicated by the pneumatization of the maxillary sinus and physiological resorption of the alveolar bone. When this occurs, the residual bone between the floor of the sinus and the crestal ridge is inadequate for the placement of implants. The sinus elevation procedure provides a way to increase the amount of available bone and to allow the placement of longer implants. Materials & methods: We studied 11 patients requiring the implant placements and the maxillary sinus elevation simultaneously from 1996 to 2003 in our clinic. Nine patients were males and two patients were females, aged from 39 to 72(mean=51.6). Four patients had medical compromised states; angina pectoris, diabetes, hypertension, hepatitis. Patients didn't show any pathologic findings clinically or radiographically. We studied the success and survival rate of implants, factors increasing the osseointegrating capacity of implants. Results: The success rate of osseointegration of implants was 93%. At least 6 months after loading on implants, the survival rate of implants was 78.5%. Autogenous bone graft and adequate residual bone height(>6mm) increased survival rate of implants. Conclusion: Successful implant placement with maxillary sinus elevation mainly depends on sufficient residual bone height, healthy maxillary sinus, autogenous bone graft.

용접공에서 혈중 중금속 농도와 혈장중 Malondialdehyde, α-tocopherol 및 적혈구내 Superoxide Dismutase 활성도에 관한 연구

이원진,장성훈,황천현,천병철,김해준 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

We investigated the association between the oxidative stress and the concentration of heavy metals in blood among welders. The study subjects were male manual CO₂welders(N=127) exposed to several heavy metals. The age distribution was from 20 to 63(GM=33.7) and the geometric mean(GM) of work duration was 4.2 years. We analyze the level of blood lead, cadmium, manganese and chromium which was related with the oxidative stress in the animal studies. Blood selenuim, plasma malondialdehyde(MDA), plasma α-tocopherol and erythrocyte superoxide dismutase(SOD) were analyzed as biological markers of the oxidative stress. The results of univariate analysis showed that the plasma MDA was significantly correlated with α-tocopherol(r=0.327) and blood selenium(r=0.313) concentration. But we could not find out any relationship between the erythrocyte SOD activities and those metal concentrations. Neither smoking nor alcohol consumption was related to the level of heavy metals and the oxidative stress biomarkers. As the results of multiple regression analysis with stepwise selection method, 1) the change of MDA level were dependent with the level of α-tocopherol and blood selenium concentration(R²=19.7), 2) the plasma α-tocopherol level was dependant with MDA and blood chromium concentration(R²=15.6), 3) in case of erythrocyte SOD activity, only the duration of work was significantly selected.

放射線이 생쥐生殖細胞에 미치는 影響에 關한 硏究

千基貞,柳炳善,鄭圭會,鄭海元,李鉦浩 대한방사선 방어학회 1985 방사선방어학회지 Vol.10 No.1

The objectives of present study is to investigate genetic damage of radiation in mammalian male germ cell and to establish available screening method for determining genetic hazard by radiation. Several methods were employed to measure the genetic damage of radiation as follows: Sperm head counts, frequency occurrence of sperm with abnormal head shape, fertility, activity of LDH-X, and the induction of unscheduled DNA synthesis (U.D.S.) in male mouse were performed with the passing of time after irradiation by making use of the sequence of event that occurs during spermatogenesis. Sperm head counts and activity of LDH-X in testes were gradually reduced by increased radiation dose and with the passing of the time after irradiation. Frequency occurrence of sperm with abnormal head shape, sterile period, and the induction of unscheduled DNA synthesis were increased by increased radiation dose. It is suggested that since germ cell is a direct reflection of genetic complement, the use of male germ cell is rapid and convenient method for measuring genetic damage by radiation.

코크스 제조 및 사용 공정에서의 코크스오븐 배출물질 연구

이종천,안규동,조광성,이병국 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.2

This study was performed to evaluate the coke oven emissions (COE) and polynuclear aromatic hydrocarbon levels in coke manu- facturing industry, secondary lead smelting industry and glass bottle manufacturing industry. 1. There were no significant difference between the means of personal samples and area samples by the types of industry(p>0.05). The levels of airborne total particulates of the secondary lead smelting industry was the highest(2.30㎎/㎥), and those of the coke manu- facturing industry and glass bottle manufacturing industry were 1.95 ㎎/㎥ and 1.37 ㎎/㎥. The concentration of COE was the highest in the glass bottle manufacturing industry(0.79 ㎎/㎥), and in order of 0.19㎎/㎥ in the coke manufacturing industry and 0.05 ㎎/㎥ in the secondary lead smelting industry. COE/total particulates(%) was highest in the glass bottle manufacturing industry(58.1%) and in order of 10.3% in the coke manufacturing industry and 3.1% in secondary lead smelting industry. There were significant differences in the total particle concentration and Coe by the types of industry(p<0.05) 2. The levels of airborne total particulates was the highest at the smelting process of secondary lead smelting industry(2.30±0.72 ㎎/㎥), and the lowest at the smelting process of glass bottle manufacturing industry (0.99±1.22㎎/㎥) Concentration of COE was the highest at the casting process of glass bottle manufacturing industry (1.09±1.15㎎/㎥), the lowest at the smelting process of secondary lead smelting industry(0.06±0,03 ㎎/㎥). The COE/total particulates(%) was the highest at the casting process of glass bottle manufacturing industry(65.9±20.5%), and the lowest at the smelting process of secondary lead smelting industry(3.1±2.7%). 3. There were positive correlations between level of The airborne total particulates and concentration of COE in COKE manufacturing industry and glass bottle manufacturing industry(p<0.05), but negative correlation in secondary lead smelting industry. 4. The numbers of case and rates that over the Threshold Limit Values(TLVs) were 24 (77.4%)cases in glass bottle manufacture, 14(23.7%) cases in the coke manufacturing industry and no one case in secondary lead smelting industry. Total numbers of case and rates that over TLVs were 38(35.5%) cases. 5. The limit of detection(LOD) for PAH was 10 ㎍/㎖) in standard sample. All PAH levels of the cokes manufacturing industry and the secondary lead smelting industry and the glass bottle manufacturing industry were trace or not to detect.