서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

대학교 신입생의 특성에 관한 실태조사(Ⅱ) : 1995학년도 조선대학교 신입생을 대상으로 1995 chosun University Entrants

조용래,박상학,김상훈,표경식,김학렬,김양옥,김기순,박종 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

멧돼지 생식후 발생한 선모충증의 가족 내 집단발생사례

김에스더,편래현,박지한,김강호,최일,박홍훈,이용희,용태순,홍성관 대한감염학회 2003 감염과 화학요법 Vol.35 No.3

선모충증은 전 세계적으로 발생하는 기생충 인수공통감염의 한로 선모충의 유충에 감염된 육류를 덜 익혀 섭식시 발생하며 감염 초기에 설사, 복통의 증상이 나타나며 후기에 유충의 체내 이행으로 발열, 근염, 안검 부종 등이 동반된다. 확진은 근육 생검을 하여 피포 유충을 확인하는 것이고 최근에는 특이 항체를 측정하거나 유전자 검사와 같은 다양한 검사가 시도되고 있다. 저자 등은 4명의 한 가족이 야생 멧돼지를 생식한 후 선모충증의 전형적인 임상 증상 및 검사 소견을 보인 가족 내 집단발생사례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Trichinosis is a worldwide parasitic infection caused by ingesting an uncooked raw meat containing viable larvae of nematode Trichinella. Although most cases have been reported in Western countries, the incidence has decreased due to strict control of meat handlings and improved hygiene in these countries. In Korea, the first case of Trichinella spiralis was reported in a patient who ingested an uncooked badger. We have also experienced four cases of Trichinella spiralis infestation among family members who showed typical clinical manifestations and laboratory findings after ingesting raw wild swine meat, and herein report the finding.

방사선조사가 구루병 백서의 발치창 치유에 미치는 영향

김미경,황의환,이상래 大韓口腔顎顔面 放射線學會 2002 Imaging Science in Dentistry Vol.32 No.1

Purpose : To observe the histopathological changes following irradiation on the wound healing after tooth extraction in the rachitic rats. Materials and Methods : In order to carry out this study, the rats were divided into four groups: Group 1 (normal diet/non-irradiation group), Group 2 (normal diet/irradiation group), Group 3 (rachitogenic diet/non-irradiation group), and Group 4 (rachitogenic diet/irradiation group). Rachitic changes were induced with rachitogenic diet No. 2 (high calcium, low phosphorus, and Vitamin D deficient diet) for 5 weeks. After the extraction of both maxillary first molars of the rats in Group 2 and 4, the head and neck of the rats were irradiated with single absorbed dose of 10 Gy. The rats were sacrificed at the 1st, 5th, 10th, and 15th day after tooth extraction. The specimens including the extraction wound were sectioned, stained with the hematoxylin-eosin and Masson's trichrome method and examined under the light microscope. Results : In the Group 2, the amount of newly formed bone trabeculae on the periphery of extraction socket and osteoblastic activity were reduced. In the Group 3, epithelial fusion was not revealed on the 5th day after toothe extraction and growth rate of osteoid formation was reduced. In the Group 4, necrotized tissue at the outer surface of extraction socket and destructive changes on the alveolar bones were noted on the 10th day. Epithelial fusion was not revealed and large amounts of osteoclast were noted on alveolar bone on the 15th day. Conclusion : The healing process of wound after tooth extraction was retarded by irradiation and especially in the rachitic rats. (Korean J Oral Maxillofac Radiol 2002; 32 : 1-10)

육성-비육돈에 있어서 항균제의 첨가효과

金大鎭,李尙勳,趙弘來 東亞大學校 大學院 1986 大學院論文集 Vol.11 No.-

This experiment was conducted to examine the effect of copper sulfate, nitrovin and virginiamycin in grower-finisher ration on the pig performance of body weight gain and feed conversion. These antimicrobial agent of copper sulfate, nitrovin and virginiamycin in grower and finisher diets were added 175ppm, 20ppm and 20ppm, respectively. Pigs fed rations containing nitrovin(837gram) of average daily body weight gain were more efficient than those of copper sulfate(815gram) and virginiamycin(804gram), but rations added nitrovin(2.90) was not improved than those of copper sulfate (2.77) and virginiamycin(2.79) in feed conversion(P<0.05).

2-Deoxy-D-Glucose에 의한 대사성 쇼크가 무우스의 면역 반응에 미치는 영향

김양숙,장선일,박래길,조성경,정헌택 최신의학사 1991 最新醫學 Vol.34 No.2

계약직공무원제도의 운영 실태에 대한 분석

김상묵,강제상,김종래 한국정책학회 2003 韓國政策學會報 Vol.12 No.2

우리 나라의 경우 계약직공무원제도는 공직사회의 전문성을 제고하고 공직 개방화에 따른 정부인적자원의 효율적 관리차원에서 1998년 도입되었다. 그 후 책임운영기관제도와 개방형 직위제도가 새로이 도입되었고, 행정서비스수요에 탄력적으로 대응하기 위하여 시간제공무원제도와 외국의 우수전문인력을 공직에 충원하기 위한 외국인공무원채용제도 등을 도입하는 등 계약직 공무원제도는 그 분야와 영역이 점차 확대되고 있는 실정이다. 이 연구의 목적은, 계약직공무원제도의 운영실태를 조사·분석하고, 이를 바탕으로 도입취지의 당위성을 확인하고 향후 인사관리정책의 방향성을 탐색하고, 계약직공무원제도의 개선을 위한 실현 가능한 정책대안을 모색하고자 한다. 특히 계약직공무원의 임용과 성과관리 방안 등 인력활용시스템의 개선에 대하여 중점적으로 고찰해보고자 한다. 먼저 면담조사를 통해 계약직공무원제도 운영실태를 파악한 후 이를 토대로 설문조사를 실시하였다. 전체 계약직 공무원 전원과, 비교집단으로 각 계약직 공무원과 유사한 위치에서 비슷한 업무를 수행하는 동일한 수의 일반직 등 비계약직 공무원을 선정하여 설문조사를 실시하였다. 이를 통해 계약직공무원제도의 운영실태를 파악한 후, 그 결과를 바탕으로 제도적·운영상 개선방안을 모색하였다. Given that the contingent employee is likely to be a familiar presence in the public service workplace of the future in Korea, this study explores the realities of contingent civil service system and discusses its institutional development. It reviews the characteristics and present situations of the contingent civil service system, analyzes its problems, and suggests the alternatives for improvement. Drawing upon survey evidence from two groups, 383 non-contingent public employees and 408 contingent public employees in the central government of Korea, our study shows that there is no difference between contingent and non-contingent public employees in the main reasons why they have entered to the government and in the factors which they have considered as more important, and that the major problems of current contingent civil service system are inappropriate performance evaluation and insufficient linkage between performance and reward, while most contingent and non-contingent public employees are agreed with the purposes of contingent civil service system. Such findings are discussed for the improvement of contingent civil service system in Korea.

정상 월경주기에 따른 혈액 응고 기능의 변화 : 혈전탄성묘사도를 이용한 평가

김동찬,이진,고성훈,이준례,송희선 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: As the menstruation has been thought to be associated with abnormal hemostasis and increased fibrinolytic activities, some surgeons and even anesthesiologists tend to postpone elective surgery. Many investigators have studied individual coagulation profiles and fibrinolytic activity during the menstruation, but conventional coagulation screens are frequently inadequate for the purpose of monitoring coagulation dynamically. This study was designed to evaluate the whole dynamic hemostatic process globally during the normal menstrual cycle by the thromboelastography (TEG). Methods: Thirty six-healthy, normally menstruating female volunteers wrote a menstruation diary about their menstruation cycle. Blood samples were obtained for TEG analysis 3 days before menstruation, the 1st day of menstruation, the 2nd day of menstruation, the last day of menstruation and 5days after menstruation. TEG coagulation indices (R value, K value, α angle, WBCL160 during menstruation compared with pre- or post-menstruation period, but there was a significant decrease in the MA value on the 1st day of the menstruation. Conclusions: The result of our study showed the possibility of abnormal hemostatic function on the 1st day of menstruation. However, the more study is needed to confirm the possibility of bleeding tendency during surgery on the 1st day of menstruation. (Korean J Anesthesiol 2002; 43: 413~417)

방사선조사와 저칼슘식이가 치아형성시 Interleukin-1의 분포에 미치는 영향에 관한 연구

김일중,황의환,이상래 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : To elucidate the effects of the irradiation and calcium-deficient diet on expression of interleukin (IL)-1 during tooth formation of rat molar Materials and Methods : The pregnant three-week-old Spague-Dawley rats were used for the study. The control group was non-irradiation/normal diet group, and the experimental groups were irradiation/normal diet group and irradiation/calcium-deficient diet group . The abdomen of the rats on the 9th day of pregnancy were irradiated with single dose of 350 cGy. The rat pups were sacrificed on the 14th day after delivery and the maxillae tooth germs were taken. The specimen were prepared to make sections for light microscopy, and some of tissue sections were stained immunohistochemically with anti-IL-1 antibody. Results : In the irradiation/normal diet group, dental follicle showed fewer blood vessels, mononuclear cells, and fusions of mononuclear cells than in non-irradiation/normal diet group. Alveolar bone showed a few osteoblasts and osteoclasts. Periodontal ligament showed collagen fibers and fibroblasts with irregularity. Weak immunoreactivity for IL-1 was shown in dental follicle, alveolar bone, and periodontal ligament, In the irradiation/calcium-deficient diet group, dental follicle showed sparse cellularity. Alveolar bone showed diminished number of osteoblasts. Periodontal ligament showed irregular collagen fibers and atrophy of cementoblasts and fibroblasts. No immunore-activity for IL-1 was shown in dental follicle, alveolar bone, and periodontal ligament. Conclusion : Irradiation and calcium-deficient diet seems to cause disturbance of the expression of interleukin-1 during tooth formation of rat molar. (Korean J Oral Maxillofac Radiol 2000; 30: 159-168)