Film Session Q&A 2 : 05 ; How to remove a huge ovarian tumor in single port laparoscopic surgery using XXXL endopouch

( Jin Hwa Lee ),( Ga Won Yim ),( Eun Ji Nam ),( Sung Hoon Kim ),( Young Tae Kim ),( Sang Wun Kim ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: Demonstrate a new instrument, technique or procedure 방법: In this video, we showed how to remove huge ovarian tumors in sinlgel port laparoscopic surgery by SW KIM`s method. SW KIM`s method is the technique to put a huge ovarian tumor into a specially designed extremely large endopouch (XXXL: 30x30㎠sized) using two conventional laparoscopic needle holders and one laparoscopic grasper and gravity by changing the patient`s position. After identifying the infundibulopelvic and uteroovarian ligaments salpingooophorectomy including huge ovarian tumor was performed by LigaSure. And then ovarian tumor was located in the pelvic cavity by changing the patient`s position into reverse-trendelenberg position and a XXXL endopouch was inserted and un-rolled inside the abdominal cavity. To insert a huge tumor into the XXXL endopouch, the endopouch was opened in triangular shape. Bilateral apex of baseline of trianglular opening of the endopouch was hold by two needle holders and then the upper apex was hold by a grasper. After holding three point of endopouch opeing, the patient`s position was changed into deep trendelenberg postion, then the tumor came into the endopouch by gravity. While changing the patient`s position, 2 needle holders and a graspers were moved into the pelvic cavity from the abdominal cavity. Aftere identifying the tumor inside the endopouch, tumors could be removed through the single port opening site or transvaginally in laparoscopic hysterectomy case without spillage of ovarian tumor. 결과: The advantage of SW KIM`s method is to remove ovarian tumor without spillage in a single port laparoscopic surgery by putting it into the large endoscopic bag despite narrow space. 결론: Using a specially designed 30×30 cm sized XXXL Endopouch and SW Kim`s technique, huge ovarian tumors could be removed without spillage in single port laparoscopic surgery.

백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.

여성노인의 저항운동 시 세트구성 방법의 차이가 Myokine에 미치는 영향

김명수 ( Kim¸ Myung-soo ),이승환 ( Lee¸ Sung-hwan ),민병남 ( Min¸ Byung-nam ),김재훈 ( Kim¸ Jae-hoon1 ),방현석 ( Bang¸ Hyun-seok ),김성희 ( Kim¸ Sung-hee ) 한국융합과학회(구 한국시큐리티융합경영학회) 2020 한국융합과학회지 Vol.9 No.4

연구목적: 본 연구는 여성노인을 대상으로 저항운동 시 사용되는 set구성 방법에 중 ascending set, descending set, drop set를 각각 적용시켜 Myokine의 변화를 알아보고자 하였다. 연구방법: 연구대상은 노인복지시설을 이용하고 있는 만 65-72세 사이의 여성노인 32명을 대상으로 ascending set, 8명, descending set 8명, drop set 8명, control group 8명으로 구분하였다. 자료처리는 반복측정에 의한 이원변량분석(two-way ANOVA with repeated measure)을 사용하였으며, 유의도는 .05로 하였다. 결론: 운동프로그램은 12주간 주 3회 실시하였으며, 신체구성과 IL-15, BDNF, VEGF, Irisin의 변화를 관찰하였다. 연구결과 신체구성의 체중, 체지방률, 제지방량 모두 유의한 차이가 없었다. IL-15와 BDNF는 운동 전·후의 비교결과 Descending set와 Drop set에서 운동 후 유의하게 증가하였고, 집단 간의 차이에서 Descending set와 Drop set 집단이 대조집단에 비하여 높게 나타났다. VEGF는 운동 전·후의 비교결과 Descending set와 Drop set 집단이 유의하게 증가하였으며, 집단 간의 차이에서 Descending set와 Drop set가 Ascending set와 control group 보다 높게 나타났다. Irisin은 집단 간 차이는 없었지만 Ascending, Descending, Drop set집단에서 운동 전에 비하여 운동 후 유의한 차이로 증가하였다.. Purpose: The purpose of this study is to identify the change of Myokine by applying ascending set, descending set, and drop set which are set composition used during elderly women’s resistance training. Method: 32 participants aged 65 to 72 who were users of welfare facilities for the aged were divided into 4 groups. They were ascending set group of 8, descending set group of 8, drop set group of 8, and control group of 8. The training program was conducted 3 times a week for 12 weeks and the change of body composition, IL-15(interleukin-15), BDNF(brain derived neurotrophic factor), VEGF(Vascular endothelial growth factor) and Irisin was observed. Two-way ANOVA with repeated measure was used for data processing. Result: The result of this study is as follows. Weight, %fat, and LBM(lean body mass) without fat showed no significant change. IL-15 and BDNF increased significantly after training in Descending set group(p<.05; p<.01)and Drop set group(p<.01; p<.05). VEGF significantly increased in descending set group(p<.01) and drop set group(p<.05). Among groups, VEGF was higher in descending set and drop set groups than ascending set and control groups. Irisin showed no difference between groups, but it showed significant increase after training in ascending(p<.05), descending(p<.05), and drop set groups(p<.05).

흰쥐 뇌에서 Tyrosine Hydroxylase분비세포의 출현시기 및 분포에 관한 면역조직화학적 연구

정윤영,선희매,김영택,김남훈,안계훈,장인엽,김종중,문정석,강양수 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

The immunohistochemical (ABC method) studies on the ontogeny and localization of the catecholamine-synthesizing enzyme tyrosine hydroxylase (TH) were examined in rat brain from the 12th fetal day until the 9th postnatal day. The results obtained were as follows : 1. Tyrosine hydroxylase was first detected immunohistochemically at embryonic day 13(E13). At this stage, the TH-containing neurons were still migrating and cytologically immature. 2. The changes occuring from the early to the late prenatal stages of development appeared to be the result of an increase in the number and size of the TH-containing cells and in the length of nerve fibers. 3. The distribution of the TH-containing neurons at embryonic day 19(E19) more closely resembled catecholaminergic neurons in the adult rat brain : 1) a rhombencephalic group became the A1-7 ; 2) a ventral mesencephalic group became A8-10 ; 3) a ventral prosencephalic group and a few neurons ventral to the striatum became A11-14 ; and 4) the cells of the olfactory bulb corresponded to the A15. 4. The cytodifferentiation of the TH-immunoreactive neurons was accompanied by continued migration to form the collective catecholaminergic groups during ontogenesis. In addition, the morphology of the TH-immunoreactive neurons in the late prenatal stage resembled in the adult rat brain.

자가 면역성 간염에서 자가항체의 발현 양상과 스테로이드 치료의 효과

박기오,채경훈,허원석,강윤세,정재훈,김연수,문희석,이엄석,김선문,이병석,김남재,이헌영 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

목적 : 최근 8년간 본원에서 경험한 자기면역성 간염의 혈액학적 특징과 스테로이드의 치료효과를 알아보고자 본 연구를 시행하였다. 방법 : 1996년 이후부터 2002년까지 충남대학교 병원에서 1999년 International Autoimmune Hepatitis Group(LAHG)에서 제시한 수정 진단 기준안에 의거하여 총 진단점수가 probable 이상에 해당하는 환자들을 대상으로 임상적 특징, 검사실 및 조직 소견과 스테로이드와 azathioprine의 치료 효과를 후향적으로 조사하였다. 결과 : 9예의 환자들은 여성이 78%, 40대가 많았고, 급성 발병이 33.3%, 피로감, 식욕부진 및 황달 등이 나타났으며, 항핵항체가 55.6%에서 그리고 항평활근 항체가 77.8%에서 양성이었고, 동반 질환은 류마치스 관절염이 2예, 특발성 혈소판 감소증 1예, Henoch-Sch nlein 자반증 및 그레브스병이 각각 1예 씩이었다. 7예에 대해서 스테로이드와 azathioprine으로 치료하여 생화학적 임상적 완해가 이루어져서 유효한 치료 결과를 얻었다. 결론 : 자가면역성 간염은 우리 나라에서 원인을 찾을 수 없는 만성 간질환의 경우, 특히 중년여성에서 다른 자가면역성 질환이 동반되었을 때 자가면역성 간염을 의심하여 자가항체 선별검사를 시행해 보아야 할 것으로 생각된다. 향후 다기관 연구를 통하여 좀 더 많은 증례를 모으고 전향적인 연구를 시행하여야 할 필요가 있다. Although autoimmune hepatitis(AIH) is common in western contries, some studties have been reported in Korea. The aim of the study was to analyze the clinical and histological features and expression pattern of the autoantibody and to examine clinical course of AIH in Korea. For 9 patients diagnosed as having AIH in our hospital since 1996, we reviewed medical records and analyzed clinical and laboratory findings retrospectively. They had a probable or definite AIH according to the revised criteria of International AIH group. The mean age was 42.7(21∼68)years and 7(77.8%) were female. Three of them(33.3%) showed acute hepatitis and five of them showed cirrhosis. Fatigue and anorexia were the most frequently complained symptoms(55.6%). Four patients(44.4%) were accompanied with other autoimmune diseases. Antinuclear antibody was detected in 5(55.6%) and anti-smooth muscle antibody was detected in 7(77.8%). Three patients showed focal picemeal necrosis and four showed periportal fibrosis. Among 7 patients who received immunosuppressive therapy, six patients(85.7%) showed initial response. and biochemical and serologic remission were achived in 5(71.4%) and 3(42.8%) patients, AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. AIH should be suspected in female patients with unknown chronic liver disease of unknown etiolgy, especially accompanied with other autoimmune disease. The clinical characteristics of AIH may not be quite different from those of Western countries.

유해화학물질의 계통분석

박성우,박유신,이진훈,유재훈,김유나,오세진,이진숙,김남이,박종신,남금문,노동석 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

유도결합 플라즈마를 이용한 백금 박막의 식각 연구

김남훈,장의구,김창일 중앙대학교 기술과학연구소 1998 기술과학연구소 논문집 Vol.28 No.-

반도체 메모리 소자가 기가 비트급 이상으로 집적화 되어짐에 따라서, DRAM의 정전 용량 확보를 위하여 강유전체막 캐패시터의 연구에 관심이 집중되어졌다. 일반적으로 강유전체 물질들은 하부전극 물질 위에 sol-gel법 등과 같은 고온-산소 분위기의 화학적 방법으로 증착되어진다. 백금은 그 화학적 안정도 때문에 가장 유력한 하부 전극 물질로 대두되고 있다. 하지만, 백금은 어떠한 식각 가스와도 쉽게 휘발성 물질을 생성하지 않는 단점이 있기 때문에 플라즈마 식각의 어려움이 있다. 따라서, 고집적 메모리 소자의 개발을 위해서는 백금 박막의 식각에 관한 연구가 선결되어져야 한다. 본논문에서는 유도 결합 Cl₂/AR, HBr/Cl₂/Ar 플라즈마를 이용한 백금 박막의 식가에 관한 연구를 수행하였다. 또한 O₂ 가스첨각가 백금 박막의 식각에 미치는 영향에 고나하여 연구하였다. 플라즈마 진단은 Langmuir 탐침과 OES 및 QMS를 이용하였고, 식각 후 표면 반응에 관한 조사는 XPS를 이용하였으며 식각 형상은 SEM을 이용해서 관찰하였다. 처음으로, Cl₂/Ar 프라즈마를 이용한 식각 하였을 때 보다도, 10% Cl₂/90% Ar 조성비일 때가 분당 1450A 정도로 더 높았다. 하지만, 식각 형상에서 펜스 현상이 SEM 사진을 통해서 관찰되어졌고, XPS 분석에 의해 그 주용 성분이 Pt-Cl의 화합물 형태임을 확인하였다. 다음으로 HBr 가스의 백금 박막의 식각에 미치는 영향에 대한 연구를 수행하였다. HBr 가스의 분압이 높아질수록 마스트로서의 산화막에 대한 선택비는 다소 향상되는 반면, 백금 박막의 식각 속도는 현저히 감소함을 볼 수 있었다. 마지막으로 O₂ 가스의 첨가가 백금 박막의 식각에 미치는 효과에 대한 연구를 수행하였다. 10% Cl₂/90% Ar 가스 조성비를 유지할 수 O₂ 가스를 5% 첨가하였을 때, 식각 속도의 저하 없이 펜스 현상이 사라짐과 식각 속도의 저하 없이 펜스 현상이 사라짐과 식각 경사도가 60°가량으로 향상되어짐을 관찰할 수 있었다. 또한 산화막과의 선택비는 2.4 이상으로 양호한 결과를 얻을 수 있었다. As highly integrated memory device develops above giga bit, dynamic random access memory (DRAM) requires the capacitor of high dielectric films. Generally, high dielectric materials are prepared on the bottom electrode by chemical methods including sol-gel method with high temperature and oxygen ambient. Pt is the most promising material as bottom electrode owing to its good chemical stability. However, Pt has the drawback of plasma etching because Pt does not easily produce volatile compounds with any etching gas. Therefore, it is the first priority to develop the technology for plasma etching of Pt film in order to achieve the highly integrated memory device. In this study, the etching mechanism of Pt film in inductively coupled plasma etching of Pt film in inductively coupled plasma (ICP) were investigated by using Cl₂/Ar, HBr/Cl₂/Ar plasmas, respectively. And then the additive O₂ gas influence on the etching of Pt film was examined. Surface reaction of Pt etching was investigated by X-ray photoelectron spectroscopy(XPS). Etch profile was observed by scanning electron microscopy (SEM). And plasma characteristics was investigated by Langmuir probe, optical emission spectroscopy (OES) and quadrapole mass spectrometer (QMS). First, the experimental results etched by using Cl /Ar gas chemistry. It is found that the highest etch rate as about 1450 A was obtained at 10% Cl₂/90% Ar gas mixing ratio. However, the fence phenomenon was observed by SEM photograph. The redeposited materials on the pattern sidewall were analyzed into mainly gas in (HB+Cl₂) gas mixing under 90% Ar gas mixing made the fence-free profile and raised the etch slope as about 60° without reducing etch rate of Pt film. And the selectivity increases above 2.4.

공동브랜드 전략으로서 전통식품 패키지디자인 연구

김남훈 한국비쥬얼디자인학회 2001 한국디자인포럼 Vol.6 No.-

If marketing is defined as "producing new added values", its effective methods of producing these added values may include price reduction of products, price regulation, execution of efficient PR price, insurance of new consumer groups, management of abrupt social change and so forth. Recently as a way of increasing added values of products, "communal joint brand development program" is under study by the minor enterprises that are low in product competitiveness. The goal of "communal joint brand development program" is a step-up in sale of various regions by reducing the pre-investing to the minimum scale to minimize the risk of failure in market. Joint brand development is an effective method to maximize the image of brand where different kinds of minor enterprises take part in developing an unified product brand and in joint management of product quality and package design. This is thus the strategy of low cost and high efficiency. The subject of present paper, "study of traditional food package design as a strategy of joint brand", is traditional food, mainly agricultural and fishery products produced in regions that are relatively low in brand power compared to the industrial products of large enterprises. Its goal is to approach the package design to produce new high added values by developing "joint brand" according to regional culture and distinctive quality of products. The subject of the study is traditional food, mainly agricultural and fishery products produced in regions that are relatively low in brand power.Based on the case study of joint brand and product package design of domestic and overseas enterprises, the paper proposes a "development program of joint brand and package design" to increase the added values of domestic provincial products of traditional food. A big change in 21st century market environment is that it is the image of the product that affects the consumers' decision rather than the quality of the product. Image of brand may be the biggest crucial element in increasing the added values of produt. Especially, provincial minor enterprises tha are relatively low in competitiveness are in great need of package design strategy of products that will effectively lead to a rise in brand image. Sunkist, Miki Mouse, Blue Diamond of U.S. and German agricultural brand, Bioland are highly regarded as successful cases of joint brand development.

廣域光陽灣地域의 機能配置에 關한 硏究

金明洙,盧春變,趙南勳 순천대학 새마을연구소 1987 새마을硏究論文集 Vol.3 No.-

The wide area of kwangyang Bay will be, in the 2000s, developed into a met­roploise with the main functions such as those of manufacturing industry, shipp­ing industry and harbor works, tourist and service industry. Such a development of the said area but to the development of national economy through attempting a balanced development of our country and solving the social disadvantages caused by centralization and accumulation. With this development of the area of kwanghang Bay, Sunchon-city not only as a center of culture, education and distribution but also as a comprehensive resea-rch complex of agriculture and industry should carry out a head function in the wide area of kwnagyang Bay. It should also establish Yeochon-city as stronghold of tourism and marine transportation and make the city at the rear of kwangyang Bay carry out the synthesized function as both a port and industrial city. Yeochon city should be developed into a residential area in the back of Yeo-chon Industry Complex : the city in the back of Yulchon should be developed in to the city with the function of a garden city. In addition, with the view of meeting the great increase in tourism demand, recreation facilities should be provided, and a closer connection with the sight-seeing areas of Jiri Mountain and Hanryosudo should be also built up. For the rational distribution and the full use of all functions of the wide area of kwangyang Bay, the expansion of social indirect capital such as the de-velopment of road, harbor, airport should be given the precedence.