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(±)-Camphor가 ICR 마우스 수컷의 간 cytochrome P450 효소 활성에 미치는 영향
오은경,박형건,배기현,최옥진,최은경,최창근,한진희,정태천 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4
Effects of (±)-camphor on liver cytochrome P450 enzymes were investigated in male ICR mice. Mice were treated intraperitoneally with 0, 200, 400 and 800 mg/kg of (±) -camphor in corn oil for 3 consecutive days. Twenty four hr after the final treatment, the animals were subjected to necropsy. The activities of serum aspartate aminotransferase and serum alanine aminotransferase were slightly changed by the treatment with (±)-camphor at the doses used. Administration o(±)-camphor to mice significantly induced the hepatic activities of pentoxyresorufin O-depentylase and benzyloxyresorufin O-debenzylase and weakly induced ethoxyresorufin O-deethylase in dose-dependent manners. The present results suggested that (±)-camphor might act as a relatively specific inducer of hepatic cytochrome P450 213 in male ICR mice.
Yang Jae‐jin,Kim Hey Sung,Choi Seong Eun,Ryu Lanhee,Choi Young Jun 한국사회복지학회 2020 Asian Social Work and Policy Review Vol.14 No.1
Outsourcing has been a key policy tool for delivering a range of social services, and regarded as more effective than insourcing or direct government provision. At the same time, it has also caused many delivery issues such as principal‐agent problems, a lack of policy coordination, and poor‐quality welfare services. While the pendulum continues to swing between insourcing and outsourcing, we aim to propose a new public–private partnership model called the “hybrid insourcing model” and examine which factors influence the performance of the model. In South Korea, around 2010, the local government in Namyangju City was the first to implement the “Hope Care Center model,” a kind of hybrid insourcing model, which has been praised for its innovation and widely emulated by central and local governments. Our analysis utilizes data collected between December 2017 and January 2018 from public sector employees and civilian staff in Namyangju and a comparable city, A. From this, we draw a number of implications, both for theory and for policy. We argue that, for public–private partnerships, active cooperation and equality are the biggest factors in contributing to positive performance. These work alongside leaders with a clear vision and with employees' positive attitude
정재현,이은지,이은주,황진원,송영진,최병진,김일환,김종윤,허민영,김동욱 인제대학교 2009 仁濟醫學 Vol.30 No.-
Neonatal lupus is a rare syndrome occurring In neonates with tranplacentally acquired maternal autoantibodies, In particular anti-SSA/Ro-SSB/Ra antibodies. Manifestations include congenital heart block, cutaneous lesions, thrombocytopenia, neutropenia, pulmonary or neurological disease and hepatitis. The non-cardiac manifestations resolve by 6 months of age, congenital heart block is irreversible. We experienced a case of neonatal lupus with congenital complete heart block in a newborn of asyptomatic mother with anti-SSA/Ro-SSB/Ra antibodies.
이종호,이세영,김명진,이은진,안강민,김성민,최원재,명훈,황순정,서병무,최진영,정필훈 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2
The surgery of oral and maxillofacial area poses the risk of cranial nerve damage such as trigeminal nerve or facial nerve. Inferior alveolar nerve is prone to damage in the third molar extraction, implant installation, orthognathic surgery, open reduction and rigid fixation, and tumor ablation surgery. On the other hands,facial nerve is likely to be damaged or sacrificed with trauma or parotidectomy. In case of inferior alveolar nerve injury, the incidence is reported to be about 1.3%. The nerve function will almost recover in minimal damage, but it won't recover at last in total damage of a part of nerve unit. In latter cases, nerve regeneration in intended by allograft as nerve substitute or various route of merve condit. But the recovery with autograft is believed to be most relialbe mrthod in the rapair of long-span(longer than 15㎜)nerve defect. We have performed autologous sural nerve graft in the repair of nerve defect, which is caused by resection of benign or malignant tumor. Hereby we report the method of nerve harvesting, recovery of defected peripheral nerve and the complications of donor site with the discussion of sural nerve anatomy.
상악 정중이개 치료시 rubber band의 부적절한 사용 : A CASE REPORT
최원혁,김은정,김현정,김영진,남순현 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.3
정중이개란 상악 중절치 사이의 치간이개를 말한다. 이는 혼합 치열기에서 ugly ducking stage에 흔히 관찰할 수 있으며 일반적으로 견치가 맹출하면서 자연적으로 소실되므로 꼭 치료가 필요한 것은 아니다. 그러나 견치 맹출 후에도 정중이개가 2mm이하로 계속 존재하거나 견치 맹출 전이라도 3mm이상의 정중이개가 존재하는 경우에서는 치료의 적응증이 될 수 있다. 특히 후자의 경우 심미적인 면에서 뿐만 아니라, 이로 인해 측절치와 견치의 맹출공간이 부족해지는 문제가 발생하므로 교정치료가 권장된다. 정중이개 치료시 사용되는 장치물은 finger spring 등을 이용한 가철성 장치물과, 교정용 band, tube, bracket 등을 부착시켜 rubber elastics이나 coil spring 등을 사용하는 고정성 장치물로 나뉘어진다. 그러나 정중이개의 치료를 위해 rubber band를 band, tube, bracket 등과 같은 적절한 부가장치 없이 사용하면 rubber band가 치근은 따라 치은 하방으로 이동하게 되고 치주 인대를 파괴하며 치근단 부위에 이르러 치아동요, 치아정출 및 탈락 등 치아에 치명적인 손상을 입힐 수 있다. 본 증례는 정중이개의 치료를 위해 부적절하게 rubber band를 사용하여 외상을 받은 치아를 관찰하여 다소의 지견을 얻었기에 이를 보고하는 바이다. Maxillary median diastema is the term used when there is spacing between maxillary central incisors. The space between maxillary central incisors are often observed during ugly duckling stage. In most of the cases, as maxillary permanent canines erupt, it gradually disappears. Maxillary median diastema needs to be treated when there is up to 2mm of space between the incisors even after eruption of permanent canines or when there is 3mm of space, at least, before the eruption of the canines. Particulary, for the latter case, orthodontic treatment is recommended because not only the esthetic point of view but also to regain the eruption space for maxillary lateral incisors and canines. The appliance used for orthodontic treatment are removable appliances, using finger spring and etc, and fixed appliances, using rubber elastics and coil spring. If rubber band alone was used to treat median diastema without any other appliance such as band, tube or bracket, it will gradually move downward along the root surface. Then it will destroy the peridontal ligament and causes tooth mobility, extrusion, and avulsion. This report presents cases of damaged tooth due to improper use of rubber band when treating maxillary median diastema.