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혈액투석을 받고 있는 만성신부전증 환자에서 동 정맥루(Arteriovenous fistuls) 와 대퇴동맥과의 동맥혈가스
김현숙,손현주,조영주,윤견일,이은령 대한신장학회 1985 Kidney Research and Clinical Practice Vol.4 No.2
The validity of obtaining blood directly from arteriovenous fistulae for blood gas and pH mea- surements in 15 patients undergoing hemodialysis was examined. In such patients, blood samples were taken simultaneously from both the arterial and venous lines of the a-v fistula and from a femoral artery. The results are as follows: 1) The mean value of PCO, of venous line of a-v fistula revealed significant difference compared with femoral artery. (p(0. 01) 2) The mean value of pH, PCO, and PO, of arterial line of a-v fistula didnt show significant difference compared with femoral artery. (p)0. 05) So, we conclude that it is more convenient and safer to obtain a specimen for blood gas analysis directly from the arterial line within arterioven- ous fistula in patients undergoing hemodialysis.
임상병리 진단검사에서의 차세대염기서열분석 기술의 적용 및 발전 방향
김현숙 청주대학교 보건의료과학연구소 2019 보건의료과학연구 Vol.8 No.1
The Sanger Sequencing method, a sequencing technique of DNA that includes genetic information from living organisms, is the most popular sequencing method. However, because this method has consumed high cost and time, Next Generation Sequencing(NGS) technique has been developed to supplement this method. With the development of the NGS technique, various disease-related genes can be simultaneously analyzed from a single sample, and investigation and molecular diagnostics using genome analysis have been started in earnest. For the first time in 2013, Illumina's MiSeqDx platform and in 2014 Thermo's Ion PGM Dx system was approved by the US FDA for diagnosis. After that, researches on cancer gene discovery, cancer development research, various cancer diagnosis research and biomarker development are actively being carried out. Accordingly, major overseas companies are developing NGS platform for diagnosis and NGS has started to be applied in various medical institutions in Korea. NGS technology is expected to be applicable to the diagnostic laboratory medicine, genome research, population genetics, microorganism species identification and metagenomics, forensic DNA profiling, and industrial process. Therefore, in the future, NGS panel of various diseases will be developed and it is predicted that it will play a critial role in the development of precision medicine which is receiving the highest attention am ong medical fields.
국민정체성과 다문화태도의 관계-한·중·일 대학생을 중심으로
김현숙,최송식,김희재 한국외국어대학교 국제지역연구센터 2011 국제지역연구 Vol.15 No.2
The purpose of this study was to investigate the relationship between national identity and attitudes towards immigrants among Korean, Chinese and Japanese univ. students. The subjects were univ. students of Korean(433), Chinese (495) and Japanese(477). Data were analyzed by Factor analysis, ANOVA, Scheffe, Structural Equation Modeling, multi-group analysis. The results are following : First, ethnic and civic identity both was the highest in chinese univ. students. Ethnic identity was the lowest in Korean univ. students, and civic identity was the lowest in Japanese univ. students. Second, attitudes towards immigrants among Korean, Chinese and Japanese Univ. Students differed from items of perceived threat. Third, each sub-factor of national identity influenced mutual relation rather than independent on attitude towards immigrants. The impact of national identity on the attitudes towards immigrants, that of Japanese univ. students has significantly highest, but those of Korean and Chinese univ. students was not affected. 한·중·일 대학생의 국민정체성과 다문화태도의 관계를 탐구하였다. 이를 위해 부산대학교 사회과학연구소가 조사한 “한·중·일 대학생의 다문화태도” 자료를 사용하였으며, 일원배치분산분석(ANOVA), Scheffe 사후검정, 구조방정식 모델링, 다집단분석을 이용하였다. 연구결과, 첫째, 중국 대학생은 혈통적 정체성과 시민적 정체성 모두 비교 국가 대학생보다 높은 것으로 나타났다. 한국 대학생은 혈통적 정체성이, 일본 대학생은 시민적 정체성이 비교 국가 대학생보다 낮은 것으로 나타났다. 둘째, 다문화태도의 경우 한국 대학생들은 일자리, 경제 기여 등에서, 중국 대학생들은 사회문제, 외국 집단 거주 등에서, 일본 대학생들은 혈통훼손, 세금 증가 등에서 비교 국가 대학생보다 인지된 위협 수준이 높았다. 셋째, 국민정체성 각 하위 요인은 다문화태도에 각각 독립적이기보다는 상호 영향관계 속에서 다문화태도에 영향을 미치는 것으로 나타났다.