서울의 PPNG 발생 빈도(1990)

김재홍,김한중,노영석,김영태,김중환,황규홍,이정덕,백승철,김건우,조상현,김준영,김석민,김영호,김상순,이승한,김방순,전덕규,하상근 대한화학요법학회 1992 대한화학요법학회지 Vol.10 No.2

The prevalence of PPNG among pretreated gonorrhoeae cases isolates at the VD clinic of Choong-ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1990, 162 strains of N.gonorrhoeae were isolated, among which 80 were PPNG. The prevalence of PPNG in Seoul showed increased tendency till 1987, thereafter, it has been stationary.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

편측안면경련 환자에서의 임상적 중증도를 평가하기 위한 전기생리학적 연구

전성만,김종국,정재익,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

Ta 상·하부 전극을 가진 Ta₂O_(5) 박막 커패시터의 전기적 특성

김현주,송재성,김인성,박문흠,김상수 昌原大學校 基礎科學硏究所 2003 基礎科學硏究所論文集 Vol.15 No.-

The electrical characteristics of Tazodtantdum pentoxide) films sputtered on Ta/Ti/SiO₂/p-Si substrate were investigated. Ta(tantalum1 was used for the bottom and top electrode for the purpose of simplifying the manufacturing process in IPD's(integrated passive devices). Dielectric materials deposited on Ta/Ti/SiO₂/p-Si were annealed at 700 ℃ for 60 sec in vacuum. The XRD results showed that as-deposited Ta had a highly preferred orientation, but Ta₂O_(5) film possessed amorphous structure, which was transformed to crystalline by rapid thermal annealing. We compared the C-F, C-V, and 1nJ-E of both as-deposited and annealed dielectric thin films deposited on Ta bottom electrode. From this results, we concluded that the leakage current could be reduced by heat treatment and dielectric constant was high than Ta₂O_(5) deposited on Pt, Au, etc.. Therefore, Ta as electrode material is thought that is suitable as material to replace the precious metal electrodes and to simplity the fabrication process of the Ta₂O_(5) MIM capacitor.

개질아스팔트 콘크리트의 변형강도와 소성변형특성 연구

김광우,최선주,이문섭,홍상기,안경애,이순제 강원대학교 부설 석재복합신소재 제품연구센터 2003 석재연 논문집 Vol.8 No.-

본 연구는 정하중하에서 최대하중과 변형을 이용하여 구한 변형강도(K_(D))로부터 아스팔트 콘크리트의 소성변형 계수의 추정 가능성을 보여준다. 이 논문은 새로운 강도특성치인 K_(D)를 개발하는 김테스트 연구의 일부로 최근 2, 3단계의 연구결과이다. 19mm 편마암과 화강암 2가지 골재와 3가지 폴리머로 제조한 7가지 바인더로 같은 입도에서 소성변형 저항성이 다른 14가지 혼합물을 만들었다. 3단계에선 슬래브 공시체(30cm x 30cm x 6cm)를 제조후 반으로 나누어 한쪽 공시체에선 두 개의 김테스트 공시체 코어를 뜨고 다른 한쪽으로는 60℃ 반복주행(WT)시험을 수행하였다. 한편 2단계에선 슬래브 공시체의 가운데에서 WT 시험을 수행하고 그 양옆에서 김테스트 공시체 코어를 채취하였다. 4가지 하중봉을 사용하여 60℃에서 김 테스트를 수행하였다. 침하깊이-반복회수 곡선으로부터 최종 침하 깊이와 동적안정도 두 가지 소성변형 계수를 각 혼합물별로 구했다. 각 하중봉과 골재 별로 K_(D)와 소성변형 계수간의 통계적 상관관계 분석을 수행한 결과 K_(D)와 소성변형 계수와의 결정계수가 매우 높게(R² > 0.9) 나타났다. 그러므로 K_(D)는 소성변형 계수를 추정하는데 있어 매우 적합한 특성치이며 4cm 직경에 1cm 반경으로 원형절삭한 하중봉이 R² 가장 높게 나타나는 하중봉임을 알 수 있었다. 따라서 김테스트는 향후 소성변형을 추정하기 위한 표준화된 특성치로 사용할 수 있도록 더 연구 개발을 할 수 있을 것으로 판단되었다. This study shows predictability of rut parameters of asphalt concrete based on the deformation strength (K_(D)) which is obtained from the maximum load, deformation and size variables of loading head under simple static loading. This paper is the result of latest studies, phases 2 and 3, which are parts of Kim Test study for developing a new strength property, K_(D), for asphalt concrete. Two aggregates, gneiss and granite, with maximum size of 19mm and seven binders using three polymers(LDPE, SBS, SBR) were used to produce 14 different natures of rut resistance mixtures using the same gradation. A slab(30m x 30cm x 6m) was cut into two pieces and 2 cores for Kim test were taken from a half piece and the other piece was used for wheel tracking (WT) test at 60℃ in phase 3. In phase 2, WT test had been carried out in the middle of a whole slab and cores were taken from both sides of the wheel path along the center line. Kim test was performed using four loading heads at 60℃. Two rut parameters, depth of rut and dynamic stability, from the rut depth-cycle curve from a WT test were obtained for each mixture. Statistical analysis were performed for each loading head and aggregate to find out correlation between K_(D) values and each rut parameter. The analysis result showed that K_(D) had very high coefficient of determination (R² > 0.9) on the average with rut parameters. It was found that K_(D) is a good property that has excellent predictability for rut parameter of asphalt concretes, and the 4cm diameter loading head with 1cm curvature radius gave the best result in R². Therefore, Kim test can be further developed as a standard property for use in rut performance estimation of asphalt concretes.

Effect of Developmental Lead Exposure on the Expression of Hippocampal NMDA Receptor Subunit mRNA

Kim, Tae-Wan,Chung, In-Sung,Bae, Jae-Hoon,Shin, Dong-Hoon,Lee, Mi-Young,Kim, Joon-Sik 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

목적: in vivo 및 vitro에서 해마 신경세포의 발생단계별 NMDA 수용체 아단위 mRNA 발현에 대한 연 폭로 영향을 알아보고자 하였다. 방법: 흰쥐 해마 신경세포의 발생단계별 NMDA 수용체 NR2A, NR2B 아단위 mRNA 발현에 대한 연의 영향은 정상군과 연 폭로군의 출생 후 7일, 14일, 22일 흰쥐의 해마에서 in situ hybridization으로 mRNA 발현 정도를 densitometer로 측정하여 비교하였고, 연과 NMDA 의 세포독성은 해마 신경세포 일차배양 후 도립현미경을 이용한 형태학적인 관찰과 LDH 활성도를 이용하여 측정하였다. 결과: 연 과 NMDA 에 의한 세포독성에 대한 in vitro 실험에서 형태학적 소견과 LDH 활성도에서 해마 미성숙 신경세포와 성숙 신경세포사이의 차이가 있었으므로, 연과 NMDA 독성효과는 해마 신경세포의 발달 단계에 따라 차이가 있다. 정상군의 해마에서의 NR2A mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나, NR2B mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나 NR2B mRNA 발현은 연령의 증가에 따른 변화가 없었다. 연 폭로에 희한 NR2A mRNA 발현은 유의하게 감소하였으나(p<0.05), NR2B mRNA 발현은 변화가 나타나지 않았다. 만성적 연 폭로는 NR2A를 포함하는 NMDA 수용체를 감소시킬 수 있음을 알 수 있다. 결론: 연은 해마신경세포의 발생단계에서 NMDA 수용체 아단위 특히 NR2A mRNA 발현의 변화를 야기하여 시냅스 신호 전달에 영향을 나타냄을 알 수 있었다. Hippocampus

필리핀 여행 후 발생한 쯔쯔가무시병 1예

김계형,김낙현,김문석,김충종,전재현,박완범,장원종,박상원,김익상,오명돈,최강원 대한감염학회 2008 감염과 화학요법 Vol.40 No.6

Infectious diseases imported from other countries have increased as more and more Koreans are going abroad for various purposes. Tsutsugamushi disease from other endemic area such as Southeast Asia is important, because it can occur in any season and eschar may be absent. We report a case of imported tsutsugamushi disease acquired in the Philippines. A patient presented with fever, headache, and maculopapular skin rash. However, eschar was absent. Polymerase chain reaction (PCR) for 56-kDa gene of Orientia tsutsugamushi using buffy coat was positive. Serum indirect immunofluorescent antibody assay was initially negative but became positive with a titer of 1:320 at follow-up, Sequencing analysis revealed the strain to be 100% identical to the TW73R strain identified in Taiwan. After the patient received doxycycline, body temperature normalized in 12 hours. Tsutsugamushi disease is one of the differential diagnoses that should be included for patients with fever who have recently returned from Southeast Asian countries. PCR for O. tsutsugamushi using patient's buffy coat was useful for early diagnosis.

子宮內膜搔爬術 21例의 鍼麻醉效果에 대한 臨床的 硏究

金在圭,金相佑,李宜暻,金建植,金相佑,南相永 경희대학교 1997 慶熙醫學 Vol.13 No.1

여중생들의 신체조성과 심폐기능 및 심박수 회복율에 관한 비교 연구 : 비만 여중생과 정상 여중생을 중심으로

김태운,신군수,김종인,이광무,김성헌,안병철,고기준,한재웅,이재규 釜山大學校 附設 體育科學硏究所 1996 體育科學硏究所 論文集 Vol.12 No.-

The purpose of this study was to compare and analyze the relation between body composition, cardiorespiratory functions and percent heart rate recovery in obese and normal middle school female students. We used total of 12 middle school female students(3rd grade) as subject and devided them into two groups : The measurement items of cardiorespiratory functions were HR, VE, RQ, VO₂, VCO₂, VO₂/kg, O₂pulse, VE/VO₂, VE/VCO₂, before and after treadmill exercise load. The statistical analysis were M±SD and t-test for groups(α=.05) using ?? statistical package. The conclusion of this study was as follows ; 1. In 5 items(FM, LBM, %Fat, TBW, BMI) all of body composition, obese group has been significantly higher than normal group(P<0.01). 2. In heart rate and VO₂ of resting(before exercise loads) cardiorespiratory functions, normal group has been significantly higher than obese group(P<0.05). 3. In VEmax of cardiorespiratory functions after exercise loads, obese group has been significantly higher than normal group(P<0.05), and in VO₂max, obese group has been significantly higher than normal group(P<0.01). 4. In 1, 3, 5 minute percent recovery all of percent heart rate recovery after exercise loads, normal group has been higher than obese group but there was no statistical significant difference.