http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
하상근,문은정,이민재,박혜민,유은숙,오명숙,김선여 한국약용작물학회 2009 한국약용작물학회지 Vol.17 No.4
This study was carried out to investigate the effect of Cinnamomum camphora on melanogenesis. The MeOH extract of Cinnamomum camphora inhibited mushroom tyrosinase activity in dose-dependent manner. Moreover, it significantly suppressed the melanin production in melan-a cells at the concentration of 100μ/ml. The MeOH extract was partitioned with ethyl acetate, n-butanol and water. Among them, the BuOH soluble fraction exhibited significant inhibitory effect on mushroom tyrosinase. In addition, the BuOH soluble fraction reduced the melanin production in melan-a cells. But, the BuOH soluble fraction had less inhibition effects on melan-a cell originated tyrosinase. So, it was performed western blotting for melanogenic proteins (tyrosinase, tyrosinase-related protein (TRP-2)) using melan-a cells. The BuOH soluble fraction inhibited the protein expression of tyrosinase at the concentration of 100μ/ml. The results suggested that the BuOH soluble fraction of C. camphora might be a potent inhibitor of melanin biosynthesis in melan-a cells.
자외선으로 유도한 Arthrospira platensis (Spirulina) 변이주의 UV-B로 유도된인간 피부 섬유아세포 손상에 대한 보호 효능
하상근,이재화,이상훈 한국키틴키토산학회 2019 한국키틴키토산학회지 Vol.24 No.4
In this study, we investigated the protective effect of UV-induced Arthrospira platensis (Spirulina) mutant and its possible mechanisms on UV-B irradiated human dermal fibroblasts (HDFs) injury. Ultraviolet rays were irradiated in order to induce the mutation of A. platensis and 5 strains were selected with respect to better growth. Among the 5 extracts of A. platensis mutants, UV1-2 mutant extract showed significant increase of type I procollagen synthesis and inhibition of MMP-1 expression. Transcription factors NF-κB and AP-1 were downregulated by UV1-2 in a dose-dependent manner. Moreover, UV1-2 mutant extract blocked MAPKs pathway, which is upstream signalling of NF-κB activation. This study suggests that UV1-2 mutant extract can be used as a therapeutic agent to prevent UV-B induced skin photoaging.
Agricultural Status and Soils in Korea
하상근,정덕영 한국토양비료학회 2012 한국토양비료학회지 Vol.45 No.1
Korea’s agriculture had many inherent problems. Korea is a mountainous country with only 22 percent farmland and less rainfall than most other neighboring rice-growing countries. A major land reform in the late 1940s and early 1950s spread ownership of land to the rural peasantry. Individual holdings, however, were too small or too spread out to provide families with much chance to produce a significant quantity of food. The enormous growth of urban areas led to a rapid decrease of available farmland, while at the same time population increases and bigger incomes meant that the demand for food greatly outstripped supply. The result of these developments was that by the late 1980s roughly half of Korea’s needs, mainly wheat and animal feed corn, was imported. Korea’s agriculture is facing a new round of difficulties from the inevitable process of market opening. Therefore, we have reviewed the agricultural status and soils in Korea how we can meet the coming issues with respect to production and prospect based on the government documents and articles published on the journals.
사회적 자본이 시민참여에 미치는 영향에 관한 종단연구 -광화문 촛불 참여 전ㆍ후를 중심으로-
하상근 참여연대 2020 시민과세계 Vol.- No.36
This study is a time-series study through Trend-Data to see how Korean society's civic participation and social capital have changed before and after the candlelight vigils in Gwanghwamun. In particular, the impact factors before and after the candlelight vigils in Gwanghwamun were compared and analyzed, assuming that social capital would affect civic participation (political participation). The study found that the level of civic engagement (political participation) after the candlelight vigils in Gwanghwamun increased almost twice and was statistically significant. A common variable with significant power of determining the political participation of citizens was identified as a social bond variable in the investigation before and after the candlelight vigils in Gwanghwamun. This shows that regardless of the participation of the candlelight vigils in Gwanghwamun, the community's ties continue to affect citizens' political participation. 이 연구는 광화문 촛불 참여 전ㆍ후를 중심으로 시민참여에 대한 사회적 자본의 영향에 관한 종단적 비교연구이다. 이 연구를 통해 사회적 자본과 시민참여 간에 어떠한 인과관계가 있는지, 특히 광화문 촛불 참여를 전ㆍ후로 어떤 차이가 있는지를 추세 자료(Trend-Data)를 통해 비교⋅분석하고자 하였다. 분석결과, 광화문 촛불 참여 이후의 시민참여(비제도적 정치참여)는 그 이전에 비해 거의 두 배 수준으로 증가하였고, 통계적으로 유의미한 차이가 있었다. 그리고 시민참여(종속변수)에 대한 사회적 자본(독립변수)의 전기조사와 후기조사에서 판별력 있는 공통변수로는 사회(지역)유대 변수(단체 활동의 적극성, 지역 행사 참여, 지역사회 기관방문 및 의견제시 등)로 확인되었다. 이는 지역사회의 유대관계가 광화문 촛불 참여와 관계없이 시민참여에 지속적으로 영향을 미친다는 사실을 확인할 수 있었다. 아울러 특기 사항으로는 광화문 촛불 참여 이후 시민들이 제도적 규범(선거참여, 조세순응)에 대해 더 적극적인 점이다. 이는 한국사회에서 정치적인 변화를 희망하는 시민들이 제도규범에 대한 자발적인 노력으로 시민참여에 더 긍정적인 영향을 미치고 있음을 나타내는 것이다.