서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

공극 매질체에서 이온강도의 변화에 따른 박테리아의 부ㆍ탈착

이창구 ( Lee Chang-gu ),박성직 ( Park Seong-jik ),김현정 ( Kim Hyon-chong ),한용운 ( Han Yong-un ),김성배 ( Kim Song-bae ) 한국농공학회 2008 한국농공학회 학술대회초록집 Vol.2008 No.-

Column experiments were performed to investigate the influence of ionic strength on the attachment and detachment of Staphylococcus aureus to quartz sand and iron-coated sand. Experimental results showed that the mass recovery in quartz sand decreased with increasing ionic strength and bacteria detachment was occurred when ionic strength was changed. In the coated sand, however, the mass recovery remained constant even though ionic strength was changed. Also, no detachment occurred with ionic strength change.

A neurometabolite study of chronic daily headache in patients with systemic lupus erythematosus using magnetic resonance spectroscopy: comparison with fibromyalgia patients and healthy controls

( Chang-nam Son ),( Sang-hyon Kim ),( Hyuk Won Chang ),( Ji-min Kim ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.6

Background/Aims: Neuropsychiatric systemic lupus erythematosus (SLE) includes a broad spectrum of neurologic and psychiatric manifestations. One of the most commonly observed neuropsychiatric symptoms is headache. However, the lack of specific clinical distinctions for headache in SLE has made it diffi cult to elucidate its pathophysiology. The aim of this study is to evaluate the neurometabolic changes using Proton Magnetic Resonance Spectroscopy (1H-MRS) in patients with SLE who suffer from chronic daily headache (CDH). Methods: SLE and fibromyalgia patients with CDH and healthy controls were recruited (n = 9, n = 5, and n = 6, respectively). 1H-MRS metabolite ratios were evaluated in bilateral basal ganglia (BG) and bilateral peritrigonal white matter (PWM). Results: 1H-MRS showed a significantly decreased N-acetylaspartate (NAA)/creatine (Cr) ratio in right BG in SLE patients with CDH compared to fibromyalgia patients with CDH and normal controls (p = 0.029 and p = 0.020, respectively). Left PWM NAA/Cr and choline/Cr ratios in SLE patients with CDH were lower than those in fibromyalgia patients with CDH (p = 0.019 and p = 0.029, respectively). Conclusions: This study suggests the possibility that CDH in patients with SLE might be associated with neuronal dysfunction and neurometabolic changes.

Kluyveromyces fragilis와 유산균의 혼합 Starter를 이용하여 제조한 알콜 발효유에 관한 연구

조좌형,김창한,한석현 건국대학교 동물자원연구센터 1993 動物資源硏究誌 Vol.18 No.-

본 연구는 10% 환원 탈지유에 효모 K.fragilis와 유산균 Str. lactis 및 L. bulgaricus의 혼합 starter를 접종시켜 30℃에서 7일간 발효시켜면서 산 생성량, 당 함량 변화, Amino태 질소함량 변화, CO₂생성량, 알콜 생성량, 유산균 및 효모수, 각 조성분의 변화를 검토하였는바 얻어진 결과는 다음과 같다. 1) K.fragilis와 L.bulgaricus의 혼합 starter를 접종하여 알콜 발효유를 제조하였을 경우가 K.fragilis와 Str.lactis의 혼합 starter를 접종하였을 때보다 산 생성량이 현저하게 높았으며, starter의 첨가량에 따른 산 생성량에 있어서 발효 초기에 약간의 차이를 보였으나 그 이후에는 거의 변화가 없었다. 2) 유산균과 효모의 starter 첨가량에 따른 당함량 변화는 각 시험구 모두 발효 36시간까지 급속히 감소하였다. 3) Amino태 질소량은 발효 7일까지 서서히 증가되었으나 그 이후는 감소하였다. 4) CO₂생성량은 K.fragilis와 Str.lactis의 혼합 starter를 이용하였을 경우가 K.fragilis와 L.bularicus은 혼합 starger를 이용하였을 때보다 현저하게 많았다. 5) 알콜 생성량에 있어서 5%와 2%의 K.fragilis starter를 접종하였을 경우 발효 36∼48시간까지는 상당한 차이를 나타내었으며, 발효 72시간째에는 알콜 생성이 거의 완료되었다. 6) 알콜 발효유의 유산균수는 Str. lactis starter를 접종하였을 때가 L. bulagricus starter를 접종하였을 때보다 약간 많았으나 발효 6일째는 모두 유산균수가 10³/ml 정도였다. 7) 알콜 발효유의 효모수는 발효 48시간까지 증가한 후 점차 감소하였고, 혼합 starter의 접종량간의 차이는 거의 없었다. 8) 조성분중 조단백질 함량은 발효중기(발효 72시간)에 약간 감소하였으나 발효가 종료된 7일째는 발효 시작때와 거의 같았고, 조지방 함량은 K.fragilis와 L.bulgaricus의 혼합 starter를 접종하였을 경우가 현저하게 증가하였고, 총고형분은 발효가 진행되면서 점차 감소하였으며, 조회분은 발효기간중 거의 변화가 없었다. Changes of acidity, sugar content, amino nitrogen content, CO₂gas, ethanol content, lactic acid bacteria, yeast cell count and chemical composition were investigated to elucidate on the characteristics of alcohol fermentd milk with mixed starter of Kluyveromyces fragilis and lactic acid bacteria incubated at 30˚C for 7 days. The titratable acidity were significantly hihger on the mixed starter with K.fragilis and L. bulgaricus than on the mixed started K. fragilis and Str. lactis. And it showed a little deference at the begining of fermentation according to the quantities of lactic acid bacteria and yeast which were added, but after that showed no more deference. Changes of sugar content by the quantities of lactic acid bacteria and yeast were quickly made up fermentation within 36 hours. The amino-nitrogen content were gradually increased untill 7th day in alcohol fermented milk, but it gradually decreased after that. The CO₂gas of K.fragilis which had sugar as an increasing source of fermentation was noticeably higher in the mixed starter of K. fragilis and Str. lactis than that of K.fragilis and L. bularicus. The ethanol content in alcohol fermented milk was significantly untill 36∼48 hours of fermentation by adding 2% and 5% of yeast. The lactic acid bacteria counted on the BCP agar in addition of Str.lactis has a little more lactic acid bacteria than L. bulgaricus, but they ceased to exist at the 6th day of fermentation. The number of yeast cells were counted in YM agar, that was increased within 48 hours of fermentation, and decreased gradually after that, and it showes little deference even by the adding quantities. The protein was decreased a little during the fermentation. At the last 7th day of fermentation, the amount of protein was the same as initial one. The fat was significantly increased in the mixed started of K.fragilis and L.bulgaricus. The total solid matter was gradually decreased during the fermentation, and the ash showed little change during the fermentation.

아윤 아파두라이의 scape 개념을 통한 문화의 세계화와 현대건축의 상관관계 고찰

장근수,김현하,임종엽 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

Today's culture represents its process of fragmentation. Recognizing this feature, this study will examine the conceptional difference between Modernity and cultural globalization based on the concept of Arjun Appadurai's Scapes. Then this study will consider the relationship between cultural globalization and contemporary architecture, by studying on design processes of contemporary architects who attempt to construct cultural flow as an experience element.

갑상선 수질암과 갑상선 유두암의 충돌종양: 5예 증례보고

정호철,김제룡,안병현,이진선,장일성,김진만1,Ho Chul Jeong,Je Ryong Kim,Byong Hyon Ahn,Jin Sun Lee,Eil Sung Chang,Jin Man Kim1 대한갑상선-내분비외과학회 2014 The Koreran journal of Endocrine Surgery Vol.14 No.1

Medullary thyroid carcinoma and papillary thyroid carcinoma are different subtypes of thyroid carcinoma. The concomitant occurrence of medullary thyroid carcinoma and papil-lary thyroid carcinoma as a collision tumor is rare. We describe five cases of medullary and papillary thyroid carcinoma as a collision tumor. Four women and one man underwent thyroidectomy for treatment of thyroid cancer. Collision tumor was then detected by histopathologic finding. Genetic testing, point mutation of the BRAF gene or mutation of the RET gene was performed in three cases. However, only one case had point mutation of the BRAF gene. Exact diagnosis of this uncommon event is important because the strategies for treatment of papillary thyroid carcinoma and medullary thyroid carcinoma are different.

Effect of Stellate Ganglion Block on the Cerebrovascular System: Magnetic Resonance Angiography Study

Kang, Chang-Ki,Oh, Seung-Taek,Chung, Rack Kyung,Lee, Hyon,Park, Chan-A,Kim, Young-Bo,Yoo, Jeong Hyun,Kim, Dong Yeon,Cho, Zang-Hee American Society of Anesthesiologists, Inc. 2010 Anesthesiology Vol.113 No.4

BACKGROUND:: Several studies have shown that stellate ganglion block (SGB) is an effective treatment for certain cerebrovascular related diseases; however, the direct effect of SGB on the cerebral vasculature is still unknown. The present study investigated the effect of SGB on the cerebral vascular system using magnetic resonance angiography. METHODS:: Time-of-flight magnetic resonance angiography images of 19 healthy female volunteers (mean ages of 46.4 ± 8.9 yr) were obtained before and after SGB with 1.5-T magnetic resonance imaging. The authors determined successful interruption of sympathetic innervation to the head with the appearance of Horner syndrome and conjunctival injection. We measured changes in the average signal intensity and diameter of the major intracranial and extracranial arteries and their branches, which were presented with mean (±SE). RESULTS:: The signal intensity changes were observed mainly in the ipsilateral extracranial vessels; the external carotid artery (11.2%, P < 0.001) and its downstream branches, such as the occipital artery (9.5%, P < 0.001) and superficial temporal artery (14.1%, P < 0.001). In contrast, the intensities of the intracranial arteries did not change with the exception of the ipsilateral ophthalmic artery, which increased significantly (10.0%, P = 0.008). After SGB, only the diameter of the ipsilateral external carotid artery was significantly increased (26.5%, P < 0.001). CONCLUSIONS:: We were able to observe significant changes in the extracranial vessels, whereas the intracranial vessels were relatively unaffected (except for the ophthalmic artery), demonstrating that both perivascular nerve control and sympathetic nerve control mechanisms may contribute to the control of intracranial and extracranial blood vessels, respectively, after SGB.

ORIGLNAL PAPER : Effects of vitamin D supplementation and circuit training on indices of obesity and insulin resistance in T2D and vitamin D deficient elderly women

( Hyoung Jun Kim ),( Chang Kyun Kang ),( Hyon Park ),( Man Gyoon Lee ) 한국운동영양학회 2014 Physical Activity and Nutrition (Phys Act Nutr) Vol.18 No.3

Effects of vitamin D supplementation and circuit training on indices of obesity and insulin resistance in T2D and vitamin D deficient elderly women. JENB., Vol. 18, No. 3, pp.249-257,2014 [Purpose]The purpose of this study was to investigate the effects of vitamin D supplementation and circuit training on body composition, abdominal fat, blood lipids, and insulin resistance in T2D and vitamin D deficient elderly women. [Methods]Fifty-two elderly women were randomly assigned to either the vitamin D supplementation with circuit training group (D+T: n= 15), the circuit training group (T: n = 13), the vitamin D supplementation group (D: n = 11), or the control group (CON: n= 13). The subjects in D took vitamin D supplements at 1,200 IU per day for 12 weeks; the subjects in T exercised 3 to 4times per week, 25 to 40 minutes per session for 12 weeks; and the subjects in D+T participated in both treatments. Subjectsin CON were asked to maintain normal daily life pattern for the duration of the study. Body composition, abdominal fat, bloodlipids, and surrogate indices for insulin resistance were measured at pre- and post-test and the data were compared among the four groups and between two tests by utilizing two-way ANOVA with repeated measures. The main results of the present study were as follows: [Results] 1) Body weight, fat mass, percent body fat, and BMI decreased significantly in T, whereas there were no significant changes in the variables in D and CON. Lean body mass showed no significant changes in all groups. 2) TFA and SFA decreased significantly in T, whereas there were no significant changes in the variables in D and CON. The other abdominal fat related variables showed no significant changes in all groups. 3) TC, TG, HDL-C, and LDL-C showed improvements in T, whereas there were no significant changes in the variables in D and CON. 4) Fasting glucose, fasting insulin, and HOMA-IRtended to be lower in D+T. [Conclusion]It was concluded that the 12 weeks of vitamin D supplementation and circuit training would have positive effects on abdominal fat and blood lipid profiles in T2D and vitamin D deficient elderly women. Vitamin D supplementation was especially effective when it was complemented with exercise training. [Key words]Diabetes, Circuit training, Vitamin D, Elderly, Abdominal fat, Insulin resistance.

사람 신경 간세포에서 도파민 신경세포 분화유도에 대한 Nurr 1 유전자의 역할 규명

김한집(Han Jip Kim),이학섭(Haksup Lee),김현창(Hyon Chang Kim),민철기(Churl Ki Min),이명애(Myung Ae Lee),김승업(Seung Up Kim),한진(Jin Han),염재범(Jae Boum Youm),김나리(Nari Kim),박원선(Won Sun Park),김태호(Taeho Kim),김의용(Euiyong Kim 한국생물공학회 2005 KSBB Journal Vol.20 No.5

Insect Diversity of Mt. Oseosan

Hong, Eui-Jeong,Jeon, Yong-Lak,Yoon, Ju-Chang,Kim, Jin-Young,Lee, Min-Ho,Kim, Jae-Won,Park, Seong-Joon,Kim, Ki-Gyoung,Kim, Joong-Hyon,Kim, Byung-Jin National Science Museum of Korea 2012 Journal of Korean nature Vol.5 No.3

This study were performed from April in 2010 to August in 2011, through regular surveys insects to obtain the list, to measure and assess Mt. Oseosan ecosystem's natural or artificial change, to provide data for systematic management and preservation of the contents of insects. Total 446 species of 108 families belonging to 11 orders were identified. Therefore, The species composition of insect from Mt. Oseosan by present study and previous literatures was a total of 566 species of 122 families under 11 orders including 7 endermic species, 13 management of exotic species, 9 species of IUCN Red List and 73 designated species: Lepidoptera (215 species, 38%) which was the highest, Coleoptera (159 species, 28.1%), Hemiptera(89 species, 15.7%) and Hymenoptera (35 species, 6.18%). We observed biological indicator species of climate change [Sympetrum pedemontanum elatum (Selys), Dichorragia nesimachus (Boisduval)] as well as risk species [Agelastica coerulea Baly, Lycorma delicatula (White), Lymantria dispar (Linn$\acute{e}$)].