1-Chloro-1-phenyl-2-carboethoxy-2-cyanoethene 유도체에 대한 thioglycolic acid 치환제의 합성

이영행,이채호,이갑상,이만구 圓光大學校 1984 論文集 Vol.18 No.2

The substitution products of thioglycolic acid to the derivatives of 1-chloro-1-phenyl-2-carboethoxy-e-cyano ethene synthesized 1-Chloro-1-phenyl-2-carboethoxy-2-cyanoethene [Ⅴ], 1-chloro-10(4-chlorophenyl)-2-carboethoxy-2-cyanoethene[Ⅳ] and 1-chloro-1-(4-methoxyphenyl)-2-carboethoxy-2-cyanoethene[Ⅶ] undergo substitution reactions with thioglycolic acid to form s-[(1-phenyl-2-carboethoxy-2-cyano) ethenyl]-thioglycolic acid s-[(1-(4-chlorophenyl)-2-carboethoxy-e-cyano] ethenyl]-thioglycolic acid and s-[1-(4-methoxyphenyl)-2-carboethoxy-2-cyano] ethenyl]-thioglycolic acid, respectively. The structure of products were identified by elemental analysis, potentiometric titration, infrared and nmr spectra.

Duplication 9p Syndrome 1례

이미경,노영래,김영훈,백청순,신미경,이진,장필상,김진택,이권행,황경태 대한소아과학회 2002 小兒科 Vol.45 No.9

체육수업 설계에 대한 고등학생의 기대요구 분석

이정흔,오병돈,조민행,유영설,이명선,조병준 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.2

Purpose: The purpose of this study was to analyze students' expectance demand towards high school physical education teaching. Methords : 392 participants randomly selected from one girls' middle school and one girl's high school in each of five tracts and then selected two classes from each of the schools. They were asked to respond to a simple Questionnaire about their views on the present physical education teaching. Results : Results showed that about one third of the participants would not choose physical education if the program were offered as an optional subject. Both male and female students ranked psychomotor domain as the top priority among the various learning objectives. Male students favored soccer and basketball while their counterparts liked badminton and volleyball. Over three-fourths of the participants suggested that students' opinions should be considered when teachers plan their program. Conclusion : The results of this study recommended that physical education teaching should be designed with considerations for professional values, societal changes as well as students' expectance on the design of physical education.

Trimethoprim 중간체의 합성에 관한 연구(II) : Diethyl 3,4,5-trimethoxybenzylmalonate의 합성 The Synthesis of Diethyl 3,4,5-trimethexybenzylmalonate

李寀浩,李英行 圓光大學校 1982 論文集 Vol.16 No.2

Trimethoprim은 그람음성균과 변형균에 대하여 광범위한 항균력을 가진다. Trimethoprim은 흔히 3,4,5-trimethoxybenzaldelyde를 출발물질로 사용하여 합성되며 그 합성자체가 복잡하고 어려운 점이 많다. 이러한 어려운 점을 피하기 위하여 3,4,5-trimethoxybenzoic acid를 출발물질로 사용하였으며 그의 acid chloride와 ethyl cyanoacetate나 diethyl malonate를 축합시켜서 Trimethoprim의 중간체인 diethyl 3,4,5-trimethoxybenzolymalonate와 diethyl 3,4,5-trimethoxybenzylmalonate를 합성하였다. Trimethoprim has a moderately broad antibacterial spectrum which includes many of the gram-negative species. This compound has always been synthesized starting from 3,4,5-trimethoxy benzaldebyde, but the synthesis of the starting material itself were very complicated and tedious. To avoid these difficulties, we used 3,4,5-trimethoxybenzoic acid as starting material and attempted to condense ethyl cyanoacetate and diethyl malonate with 3,4,5-trimethoxybenzoyl chloride. As a result, the intermediates for the synthesis of trimethoprim, diethyl 3,4,5-trimethoxybenzoylmalonate and diethyl 3,4,5-trimethoxybenzylmalonate were synthesized.

Ethyl 4-Carbetoxy-1, 1-dioxo-5, 6-2H-1, 2, 6-thiadiazin-5-ylacetate로 부터 N-Alky1-3-carbetoxy-2-pyridinones의 합성

李采浩,鄭永洙,李英行,蔡圭允,崔昌鎭 圓光大學校 基礎自然科學硏究所 1992 基礎科學硏究誌 Vol.11 No.1

흔적이론과 의미해석

이영헌,조학행,이흥수,허정 조선대학교 외국문화연구소 1980 外國文化硏究 Vol.3 No.1

표준이론(Standard Theory)에 있어서 한 문장의 의미해석은 오직 심층구조에 의해서만 가능하였다. 그러나 어떤 문장에 있어서는 심층구조의 정보만으로는 그 문장이 지니고 있는 모든 의미를 나타내주지 못하는 경우가 있기 때문에 표층구조에서도 의미해석을 하여야 할 경우가 생긴다. 이와 같은 문법기술의 궁극적 목표인 의미해석에 밝은 전망을 주지 못하는 표준이론은 확대표준이론으로 발전되었다. 확대표준이론(Extended Standard Theory)에 의하면 한 문장의 의미해석은 심층구조와 표층구조를 모두 다 들여다 보아야 가능하다. 그러므로 의미해석의 정보를 심층구조에서 뿐만 아니라 표층구조에서도 택하여야 한다면, 어떤 정보는 심층구조에서 얻어야 하고, 또 어떤 정보는 표층구조에서 얻어야 할 것이냐 하는 문제가 생긴다. 다시 말하면 심층조와 표층구조가 제공하는 정보의 구별에 따르는 문제가 생기는 의미해석의 문제도 그만큼 복잡해진다. 뿐만 아니라 두 구조가 제공하는 정보에 의한 의미해석이 복잡해짐에 따라 의미가 동일한 두 문장과 한 문장이 두개 이상의 의미를 지녔을 경우의 의미해석은 더욱 어려운 문제가 된다.

Crystal Violet의 Dimerization에 關한 吸收分光學的 硏究

李弘,李英行 圓光大學校 1981 論文集 Vol.15 No.1

The dimerization constant of crystal violet in aqueous solution has been determined by the absorption spectroscopic method and also the empirical absorption curves of its monomeric and dimeric states were presented. These calculated spectra of pure species were used for the comparison of the experimental results with the theoretical expectation.

전해산성수를 이용한 새로운 내시경 소독 시스템(Cleantop WM-1??)의 소독효율

이준행,이풍렬,송재훈,이남용,임윤정,장재권,김영호,김재준,백승운,이종철,최규완 대한감염학회 2001 감염 Vol.33 No.2

Background : Electrolyzed acid water (EAW) is a new liquid chemical germicide containing a mixture of oxidizing species and prepared by mixing a small amount of salt with tap water in an electrolyzer. We attempted an in-use evaluation of the high-level disinfection capability of Cleantop WM-1□, a new endoscope reprocessing system using EAW. Methods : Forty-seven flexible endoscopes were randomly collected just after upper endoscopic examinations and were disinfected using Cleantop WM-1□. Parts of the endoscopes without contact to EAW were disinfected with 75% ethyl alcohol. Immediately after the disinfection procedure, samples were taken from the biopsy channel (S-1), tip of the insertion tube (S-2), the umbilical cord (S-3), and the angulation knob (S-4). Results : In EAW-disinfected parts of the endoscopes, the culture-positive rates were 4.3% (2/47) in S-1 samples and 12.8% (6/47) in S-2 samples. In ethyl alcohol-disinfected area, the culture-positive rates were 2.1% (1/47) in S-3 samples and 25.5% (12/47) in S-4 samples. The colony counts of culture-positive samples ranged from 1 to 144. Pseudomonas aerugi-nasa was recovered from the angulation knob of an endoscope, but other contaminating organisms were mostly : normal flora or opportunistic pathogens. Conclusion : Although part of the endoscopes disinfected with 75% ethyl alcohol were contaminated with more organisms than EAW-disinfected areas, Cleantop WM-1□ showed a relatively good disinfection efficacy in reprocessing patient-used endoscopes. (Korean J Infect Dis 33:133∼138, 2001)

Moclobemide의 항우울 효과에 대한 평가

이귀행,박민철,노승호,백영석,이상열,김재현 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

Eighteen patients took Moclobemide for 6 weeks, who had been diagnosed as major depression based on DSM-Ⅲ-R and had had more than 16 points on the Hamilton Depression Rating Scale. After medication of Moclobemide, they were evaluated by the Hamilton Depression Rating Scale and in terms of sleep, vigilance, performance, social interactions and drive. The results were as follows ; 1. The average dosage of Moclobemide was 400±89 ㎎. 2. Antidepressant effect were checked on the all items of the Hamilton Depression Rating Scale and prominent on the items of work and activities, insomnia, suicide, somatic symptoms. 3 There were obvious changes of the antidepressive effect by the evaluation of the doctors and patients at 4 weeks after the medication of Moclobemide. 4. In the patients, 61% had positive effects on the sleep. 94% no negative effects on the vigilance. Nobody has negative effects on the social interactions and drive. 5. Side effects or physical disturbances induced by Moclobemide were not found. According to these results, it seemed that Moclobemide had clear antidepressant effects, few negative effects on the life of day time, positive effects on the sleep and somatic symptoms.

Riboflavin Tetrabutyrate의 합성에 관한 연구

李英行,李鍾律,李寀浩 圓光大學校 基礎自然科學硏究所 1983 基礎科學硏究誌 Vol.2 No.1

Riboflavin(Vitamin B_2) is a component of two closely related coenzymes, flavin mononucleotide(FMN) and flavin adenine dinucleotide(FAD). Riboflavin tetrabutyrate is more fat-soluble than riboflavin, which is highly absorbed in vivo. and hydrolysed to give riboflavin. Riboflavin tetrabutyrate has always been synthesized by general method of ester. But the use of DMAP was found be very effective for esterification of riboflavin with butyric acid.