만성 부비동염에서 섬모운동과 전산화 단층촬영에서의 상악동 점막비후의 상관관계

민양기,전상준,이재서,이철회,이강수,윤자복,이원진,박광석 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

서울시내 고등학교 위탁급식의 급식비와 투자비의 실태 및 위탁업체의 기대수준 비교 분석

양일선,배환미,김현아,신서영,조미나,박수연,차진아,이보숙 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

The purposes of this study were to a) find out the operational characteristics of the contract-managed highschool foodservice in Seoul, b) investigate the expected level of meal-price and facilities investment cost perceived by contract-managed highschool foodservice managers c) compare the present level and expected level of meal-price and facilities investment cost. From October 12 to November 13 in 2001, the questionnaires were mailed to 249 high schools which was managed by contract foodservice company with respondent rate 40.2%. Data were analyzed using SPSS Win(10.0) for descriptive analysis and one group paired t-test. The results of this study were as follows ; 1. The student enrollment of highschools run by contract-managed foodservice was 1,243 with 72.6% participation rate of school lunch program. The average meal-price was 2,138 won. The average annual period of school foodservice operation was 156.78 days per year. The average contracting period was about 3 years. 2. The average cost concerned in the facilities investment amounts 169,578,180 won at the initial investment and 25,204,092 won at the repairs and maintenance cost in the course of operation. 3. The present level of meal-price and facilities investment cost were respectively 2,136won/meal and 171,157,336.72 won. And expected level.of meal-price and amount of facilities investment cost were 2,418.75 won and 121,353,215.19 won. Comparing the present level with expected level of the meal-price and facilities investment cost, expected level of meal-price was significantly higher than the present level of meal-price(p<.001) and expected level of facilities investment cost was significantly lower than present level of facilities investment cost(p<.001).

인체에서 방사되는 생물광자(生物光子)에 대한 소고

이승호,김진수,박하준,양준모,소광섭,임사비나 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : The purpose of this study is to review research papers published by Korean research groups on biophoton of human beings based on experiment subject and methodology. Methods : In order to review human biophoton research executed in Korea, all the papers published in Korean and international journals by Korean research groups were selected. Several key foreign papers were also reviewed for clarification of this study. Based on experiment subjects, experiment methodology, and interpretation of experiment results were analyzed. On each experiment, its original interpretation was directly quoted. Issues on the experiment methodology and interpretation were expressed at the end of each subject. Results and Conclusions : We found that experiments on human biophoton were compelling. However it seemed that mom experiments, especially on their sample sizes, ate needed to demonstrate its clinical application. Interpretations based on Korean traditional medicine also need to be elaborated more. In order to do accomplish clinical application of biophoton, interdisciplinary works are required. Some suggestions on biophoton experiments were made.

당뇨병 백서의 간세포에서 Glucokinase 활성도 및 유전자 발현에 대한 인슐린의 영향

강성이,팽정령,서광식,안규정,우정택,김성운,양인명,김진우,김영설,김광원,최영길 경희대학교 유전공학연구소 1993 遺傳工學論文集 Vol.5 No.-

목적 당대사의 조절 상태에 따른 생체 변화를 분자 수준에서 이해하고자 식이 조건을 달리한 정상 백서와 화학적으로 유도된 당뇨병 백서의 간조직에서 혈당수준과 인슐린치료 정도에 따라 나타나는 글루코키나제 활성도 및 유전자 발현을 분석하였다. 방법 스트렙토조토신 정맥투여 후 당뇨병의 유발을 확인하고, 인슐린을 1일 3회 3일간 복강내로 투여하여 상태를 안정시킨 후, 인슐린 투여군은 인슐린 투여 6시간이내에 그리고 인슐린 비투여군은 24시간 후 단두하여 채혈하고 복강을 열어 간조직을 채취하였다. 채취한 간조직에서 글루코키나제 활성도는 인산화된 포도당에서 NADH의 형성을 형광분광계로 측정하였으며, 글루코키나제 유전자 mRNA발현은 Northern 분석법을 이용하였다. 성적 정상 백서에서 공복상태와 식이를 섭취한 경우에 간조직의 글루코키나제 효소의 활성은 차이가 없었으나, 글루코키나제 유전자 mRNA 발현은 증가되었다. 당뇨병이 유발된 백서의 간조직에서 글루코키나제 효소의 활성 및 글루코키나제 유전자의 mRNA 발현은 정상 백서에 비하여 낮았다. 인슐린 투쳐 후 글루코키나제 효소의 활성 및 글루코키나제 유전자의 mRNA 발현이 증가되었고, 특히 혈당이 정상화된 경우에서 글루코키나제 유전자의 mRNA 발현이 증가도었다. 결론 인슐린에 의한 간조직에서 글루코키나제 효소의 활성 및 글루코키나제 유전자의 mRNA을 증가를 볼수 있었다. 당뇨병 백서에서 인슐린 투여 후에 혈당조절이 안된 경우 간조직의 글루코키나제 유전자의 mRNA 발현이 증가가 없는 것으로 보아 글루코키나제 mRNA의 발현에는 인슐린 이외의 다른 요소가 관여할 것으로 생각된다. The liver-specific hexokinase isoenzyme, referred to as glucokinase, is thought to play a key reglulatory role in hepatic glucose metabolism. The glucokinase gene is, therefore, of interest both because of its tissue-specific expression and because of the several regulatory processes that can be analyzed. The level of hepatic glucokinase activity appears to be determined essentially by regulation of the rate of enzyme synthesis, with insulin playing a leading role as an inducer. We investigated the role of insulin for the induction of glucokinase in the liver of diabetic rats. Experimental diabetes was induced by injection of streptozotocin 7 days before the experiment. Regular insulin was given by three days intraperitoneal injection at 8-h interval. The glucokinase mRNA in the liver was estimated by Nothern blot assay, as well as by fluorometric enzyme activity assay. Glucokinase activity was not reduced in the liver of normal fasting rats as compared to normal fed rats. And glucokinase activity was reduced in the liver of diabetic rats as compared to normal rats. In diabetic rats treated with insulin, glucokinase enzyme activity were increased. But glucokinase mRNA expression was only increased in normoglycemic diabetic rat with treated with insulin as compared to hyperglycemic rat. These data indicate that insulin stimulates hepatic glucokinase enzyme activity and mRNA expression. But other hormonal or metabolic factors may be contribute to regulation of glucokinase mRNA expression.

위탁급식업체 선정에 영향을 미치는 요인에 대한 개발영업사원의 인식도 조사

김현아,양일선,이보숙,박진영 대한영양사협회 2004 대한영양사협회 학술지 Vol.10 No.2

The purpose of this study was to investigate the importance level on factors affecting the foodservice management contract perceived by the salespersons in the foodservice company. To get the data on the perceived importance level on the affecting the foodservice management contract, the questionnaires were developed by the delphi technique and modified by the pilot test. The questionnaires consisted of 4 categories and 19 items on the factors affecting the foodservice management contract and the importance level on the factors were measured by 5-likert scale. From March 12 to April 13 in 2003, the self-administrative questionnaires were mailed to the 60 salespersons. The questionnaires were responded from the 48 salespersons(respondent rate : 77%). As a result, the salesperson' perceived importance level of 「the sales ability」 was higher than those of the other categories in the private contract and the salesperson' perceived importance level of 「the evaluation of the foodservice company」 was higher than those of the other categories in the competitive bid. The importance of the 「the evaluation of the foodservice company」 between the private contract and the competitive bid was significantly different(p<.05), and the importance of 「the sales ability」 of the competitive bid was significantly higher than that of the private contract(p<.001).

The risk factors for herpes zoster in bortezomib treatment in patients with multiple myeloma

Yi, Yang-Seon,Chung, Joo-Seop,Song, Moo-Kon,Shin, Ho-Jin,Seol, Young-Mi,Choi, Young-Jin,Cho, Goon-Jae,Lee, Gyeong-Won,Moon, Joon-Ho,Hwang, In-Hye,Ahn, Kang-Hee,Lee, Hee-Sun,Shin, Kyung-Hwa,Hwang, Jong Korean Society of Hematology; Korean Society of Bl 2010 Blood Research Vol.45 No.3

<P><B>Background</B></P><P>Bortezomib has significant activity in treating multiple myeloma (MM). The risk of herpes zoster (HZ) has been reported to increase significantly with bortezomib treatment, but the predisposing factors for HZ are not clear. This study is a retrospective analysis of the relevant risk factors for HZ in Korean MM patients treated with bortezomib.</P><P><B>Methods</B></P><P>Sixty-six patients with refractory or relapsed MM who underwent chemotherapy with bortezomib were included in the study. Prophylactic antiviral drugs were not used for treatment. The following parameters were reviewed: age, gender, stage and type of MM, extent of previous treatment, history of HZ, duration from the time of diagnosis to the time of bortezomib treatment initiation, and absolute lymphocyte counts (ALC) at the time of bortezomib treatment initiation.</P><P><B>Results</B></P><P>The incidence of HZ was 16.7%. There were no intergroup differences between the HZ-positive and the HZ-negative groups with regard to a history of HZ, number of previous treatments, and exposure to steroids before bortezomib treatment. The median duration from the time of MM diagnosis to the time of bortezomib treatment initiation in the HZ-positive group was significantly shorter than that in the HZ-negative group. The median ALC at the time of bortezomib initiation in the HZ-positive group was significantly lower than that in the HZ-negative group.</P><P><B>Conclusion</B></P><P>Bortezomib itself might act as a risk factor for HZ by inhibiting cell-mediated immunity, and patients with low ALC at the time of bortezomib treatment initiation were at greater risk of HZ during bortezomib treatment.</P>

CAUSE OF TECHNICAL FAILURES OF CONICAL CROWN-RETAINED DENTURE (CCRD): A CLINICAL REPORT

Yi Yang-Jin,Cho Lee-Ra,Park Chan-Jin The Korean Academy of Prosthodonitics 2003 대한치과보철학회지 Vol.41 No.6

Conical crown-retained denture (CCRD) has been used as a very effective treatment method in cases with few remaining teeth with heterogeneous prognosis. However, in spite of many advantages of CCRD, high technical failure rate was a problem to be considered. Incorrect path of insertion and excessive retention were thought to be the main cause of technical failure and to result from laboratory procedure with a coping misfit and/or a coping transfer error. In order to prevent this error, secure anchoring of inner coping and re-examination and milling of convergence angle were recommended on the master model from pick-up impression.

Renal Subcapsular Hematoma after Percutaneous Transfemoral Angiography

Yi, Jin-Seok,Lee, Hyung-Jin,Lee, Hong-Jae,Yang, Ji-Ho The Korean Neurosurgical Society 2014 Journal of Korean neurosurgical society Vol.55 No.2

Vascular complications after percutaneous angiography include hematoma, pseudoaneurysm, arteriovenous fistula, thromboembolism, arterial laceration and infection. Hematomas may occur in the groin, thigh, retroperitoneal, intraperitoneal, or abdominal wall. A 54-year-old female underwent percutaneous transfemoral angiography for the evaluation of cerebral aneurysm. Renal subcapsular hematoma developed 3 hours after the procedure. Renal subcapsular hematoma after percutaneous angiography is very rare. We investigated the possible causes of renal subcapsular hematoma. To avoid this rare complication, we need to perform guide-wire passage carefully from the beginning of the procedure under full visual monitoring.

IN VITRO EVALUATION OF FRACTURE RESISTANCE OF VARIOUS THICKNESS FIBER- REINFORCED COMPOSITE INLAY FPD

Yi Yang-Jin,Yoon Dong-Jin,Park Chan-Jin,Cho Lee-Ra The Korean Academy of Prosthodonitics 2003 대한치과보철학회지 Vol.41 No.6

Statement of problem. In dentistry, the minimally prepared inlay resin-bonded fixed partial denture (FPD) made of new ceromer / fiber-reinforced composite (FRC) was recently introduced. However, the appropriate dimensions for the long-term success and subsequent failure strength are still unknown. Purpose. The aim of this study was to investigate the most fracture-resistible thickness combination of the ceromer / FRC using a universal testing machine and an AE analyzer. Material and Methods. A metal jig considering the dimensions of premolars and molars was milled and 56-epoxy resin dies, which had a similar elastic modulus to that of dentin, were duplicated. According to manufacturer's instructions, the FRC beams with various thicknesses (2 to 4 mm) were constructed and veneered with the 1 or 2 mm-thick ceromers. The fabricated FPDs were luted with resin cement on the resin dies and stored at room temperature for 72 hours. AE (acoustic emission) sensors were attached to both ends, the specimens were subjected to a compressive load until fracture at a crosshead speed of 0.5 mm/min. The AE and failure loads were recorded and analyzed statistically. Results. The results showed that the failure strength of the ceromer/FRC inlay FPDs was affected by the total thickness of the connectors rather than the ceromer to FRC ratio or the depth of the pulpal wall. Fracture was initiated from the interface and propagated into the ceromer layer regardless of the change in the ceromer / FRC ratio. Conclusion. Within the limitations of this study, the failure loads showed significant differences only in the case of different connector thicknesses, and no significant differences were found between the same connector thickness groups. The application of AE analysis method in a fiber-reinforced inlay FPD can be used to evaluate the fracture behavior and to analyze the precise fracture point.

A CONTROLLED CYCLIC LOADING ON THE SURFACE TREATED AND BONDED CERAMIC: STAIRCASE METHOD

Yi, Yang-Jin The Korean Academy of Prosthodonitics 2008 대한치과보철학회지 Vol.46 No.3

STATEMENT OF PROBLEM: Effect of surface treatment of ceramic under loading does not appear to have been investigated. PURPOSE: The aim of this study was to investigate the effect of surface treatment of esthetic ceramic, which is performed to increase the bonding strength, on the fracture stress under controlled cyclic loading condition. MATERIAL AND METHODS: Sixty 1.0 mm-thick specimens were made from Mark II Vitablocs (Vita Zahnfabrik, Germany) and divided into 3 groups: polished (control), sandblasted, and etched. Specimens of each group were bonded to a dentin analog material base including micro-channels to facilitate the flow of water to the bonding interface. Bonded ceramics were cyclically loaded with a flat-end piston in the water (500,000 cycles, 15Hz). Following completion of cyclic loading, specimens were examined for subsurface crack formation and subsequent stress was determined and loaded to next specimen by the staircase method according to the crack existence. RESULTS: There were significant differences of mean fatigue limit in the sandblasted (222.86 ${\pm}$ 23.42 N) and etched group (222.86 ${\pm}$ 14.16 N) when compared to polished group (251.43 ${\pm}$ 10.6 N) (P<.05; Wald-type pair-wise comparison and post hoc Bonferroni test). Of cracked specimens, surface treated group showed longer crack propagation after 24 hours. All failures originated from the radial cracking without cone crack. Fracture resistance of this study was very low and comparable to failure load in the oral cavity. CONCLUSION: Well controlled cyclic loading could induce clinically relevant cracks and fracture resistance of Mark II ceramic was relatively low applicable only to anterior restorations. Surface treatment of inner surface of feldspathic porcelain in the matsicatory area could influence lifetime of restorations.