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거대 긴장성 낭종으로 내원한 폐 Langerhans 세포 조직주증
양석철,손장원,윤호주,신동호,박성수,함시영,장세진,박용욱 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1
Pulmonary Langerhans cell histiocytosis is a hetergenous group of conditions of unknown etiology characterized by an abnormal proliferation of antigen presenting cell of bone marrow derivation known as Langerhans cells that invade and destroy distal bronchioles. The outcome is highly variable, ranging from rapid spontaneous resolution to irreversible respiratory failure. We describe a patient with biopsy-confirmed pulmonary Langerhans cell histiocytosis who presented with large tension cyst, treated with pneumothorax tube with Heimlich flutter valve.
정맥내 통증자가조절법을 이용한 Nalbuphine-Ketorolac과 Butorphanol-Ketorolac의 술후 진통효과 비교
윤석화,이원형,손수창,신용섭,김윤희,양신영 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1
This study aimed to compare analgegic efficacy, satisfaction score and side effect of nalbuphine-ketorolac and butorphanol-ketorolac by using intravenous patient controlled analgesia(IV-PCA) for postoperative anlgesia following a gastrectomy for stomach cancer. Ninety patients who had undergone gastrectomy for stomach cancer under general anesthesia were randomly divided into two groups. Each group recieived nalbuphine 50mg with ketorolac 150mg(Group 1, n=45) and butorphanol 5mg with ketorolac 150mg(Group 2, n=45) by using IV-PCA during postoperative 48hrs. Assessments for pain with numerical rating scale(NRS), and side effects were evaluated at 2hr, 6hr, 12hr, 24hr, 36hr and 48hr after the operation. There were no significant difference in NRS for pain during rest, but Group 2 requested significantly greater amount of supplementary diclofenac during first 24 hours. Side effects were higher Group 1 in pruritus, nausea and vomiting and Group 2 in sedation, nausea and vomiting. This study suggests that adding ketorolac with intravenous nalbuphine or butrophanol in using an intravenous PCA can decrease analgesics requirement and improve analgesic property without the major morbidity like respiratory depression, but needs for the careful observation and treatment on the side effects like nausea. vomiting, pruritis and sedation...
권오석,윤양진 釜山大學校 附設 體育科學硏究所 2002 體育科學硏究所 論文集 Vol.18 No.1
In this study, 4 gymnasts who were students of B University at the same time was taken and their performance of forward Handspring salto with body stretched was looked at through 3 dimensional of the body, the tract of moving and its kinematic element. It is all to provide basis data for efficient training of gymnasts and the findings are as follows: 1. From the examination of the sequence of duration phase, it appeared that in phase 1, the superior group had longer duration with long strider in home step, in phase 2, they bent their upper body making big shoulder angle and changed the straight-line motion to circular motion. And it appeared to result in efficient circular motion while in flight phase of 4 and 5. 2. It appeared that in the event 2 in which the movement of support with hands took place, the Superior group had bigger shoulder angle so that the Handspring movement was faster in its rotation on the axis of hands supporting. In event 3 of jump in feet, the hips angle was big enough to produce with its weight sufficient pressure on feet to maximize the reaction of the floor. 3. For the speed in each phase, the Superior group spurred rapid speed with the hips angle curved a little bit in event 4 in which the body made vertical angle to the floor while in handspring salto forward piked movement of the body and in event 5, the hips angle extended rapidly producing good rotation speed. In summery of all the elements considered above, big strider with the body bent to produce decisive support on the hands seemed to result in increased rotation speed in handspring, bigger pressure on feet, and good speed in handspring salto forward stretched.
한국인에서의 CYP2C19 돌연변이 유전자형의 다형성에 관한 연구
채석,채상우,양동규,김형기,권준택,염윤기 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2
The S-mephenytoin 4'-hydroxylase (CYP2C19) metabolizes a number of clinically used drugs and shows a marked interethnic difference in the incidence of the poor metabolizer (PM). Recent studies have found a third (CYP2C19*4) and forth (CYP2C19*5) mutations in Caucasians. In the present study, we genotyped 536 healthy unrelated Koreans for functionally defective alleles, CYP2C19*2, CYP2C19*3, CYP2C19*4, and CYP2C19*5. Detection of the normal (CYP2C19*1) and defective alleles was performed by polymerase chain reaction/restriction enzyme analysis. The genomic DNA was isolated from peripheral blood. The allelic frequencies of the wild-type (CYP2C19*1) and CYP2C19*2 were 72.6% and 27.4%, and the wild-type (CYP2C19*1) and CYP2C19*3 were 85.1% and 14.9%, respectively. For each CYP2C19*2 and CYP2C19*3 the observed number of three genotypes were similar to those calculated in accordance with the Hardy-Weinberg equation. The frequencies of homozygotes for CYP2C19*2, CYP2C19*3 and compound heterozygotes were 9.7%, 2.8% and 4.2%, respectively. The mutants of CYP2C19 were identified in 36 subjects (16.7%). The mutated CYP2C19*4 and CYP2C19*5 alleles were not detected in this study. These results suggest that frequency of mutants of CYP2C19 in Koreans resembled the Orientals rather than Caucasians, and we founded the racial variability of the frequencies of the CYP2C19*4 and CYP2C19*5 alleles in the Orientals.
핸드스프링 무릎굽혀 앞공중돌기동작과 몸펴 앞공중돌기동작의 운동학적 비교분석
권오석,윤양진 부산대학교 사범대학 2002 교사교육연구 Vol.41 No.-
In this study, 4 gymnasts who were students of B University at that time were taken and their performance of handspring salto forward tucked and handspring salto forward stretched at through 3 dimensional movement analysis to tell the duration for each phase of the movement, the movement of the articulation of the body, the tract of moving center of the body, and its kinematic element. It is all to provide basic data for efficient training of gymnasts and the findings are as follows: 1. The time duration for phase 1 and 2 differed each other and faster landing on hands in forward handspring salto forward stretched than in forward salto with the body bent helped the straight-line movement change to circular movement giving the handspring a big circular movement, and forward jumping on feet with rapid upright of the upper body maximized the circular radius on the axis of the jaw, contributing to rapid backward circular movement of the lower part of the body. 2. In the observation of the position of the body center, the sway of the body center and the power dispersion was smaller in general in forward salto with the body stretched than in forward salto with the body bent. And in its forward and backward position, it showed lower position in handspring phase of 1 and 2, but higher in the salto of phase 3, 4 and all these contributed to bigger and more stable circular motion. 3. Articulation angle of the body in each phase of handspring forward salto with the body bent and in forward salto with the body stretched appeared to be different through 5 phases. It had more centripetal force in forward salto with the Elbows, shoulders, hips, knees having more curve. In forward salto with the body stretched, centrifugal force appeared to be strong with the elbows, shoulders, hips, knees all being extended. To summarize, Handspring forward salto with the body bent seems to have curved articulation and be slow, while in forward salto with the body stretched, its circular movement appeared be faster with speedy landing on hands, extended knees angle for good jump, and with accelerated hips articulation. Handspring forward salto with the body stretched appeared to enhance its technical performance with far-reaching circular motion. Therefore, forward salto with the body stretched is considered to produce more gracious and dynamic motion than forward salto with the body bent does.