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      • 신암조직의 H-ras p^(21)발현에 관한 면역조직 화학적 관찰

        박용욱,허창원,유재형 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.2

        To observe the expression of the human H-ras p^21 in tumor cells with different histologic features of renal cancer, immunohistochemical studies were carried out by using avidin biotin complex immunoperoxdiase method in formalin fixed tissue sections from 29 cases of primary tumor mass and 1 case of metastatic tumor. The studies consisted of 21 cases of renal cell carcinoma, 7 cases of transitional cell carcinoma, 1 case of squamous cell carcinoma, and 1 case of metastatic choriocarcinoma. The results were as fellows: 1. Expression of H-ras p^21 was consistently increased in the granular cell type as compared with clear type of cell carcinoma. The individual tumor cells showed rather positive reation in the apical surface than of cytoplasm. 2. The non-neoplastic renal tubule was uniformly H-ras p^21 weakly positive focally, but the apical cell surface was nonreactive. 3. In renal cell carcinoma, there was no apparent correlation of H-ras p^21 expression with the size of tumor and clinical staging. 4. Expression of H-ras p^21 was consistently increased in the grade II papillary tumor as compared with grade III invasive tumor of transitional cell carcinoma, and the stronger positive reaction was observed in the superficial portion than the basal portion of tumor papillae. 5. Expression of H-ras p^21 was observed in squamous cell carcinoma of renal pelvis and metastatic choriocarcinoma.

      • KCI등재
      • KCI등재

        가골 신연술을 이용한 단중족증의 치료

        박용욱,유정한,박홍준,조양범,유선오,김완홍,Park, Yong-Wook,Yoo, Jung-Han,Park, Hong-Jun,Cho, Yang-Bum,Yu, Sun-O,Kim, Wan-Hong 대한족부족관절학회 2002 대한족부족관절학회지 Vol.6 No.1

        Purpose: To evaluate the effectiveness of callotasis using the external fixator for the treatment of brachymetatarsia. Materials and Methods: Eleven patients(15 cases) who underwent callotasis were available. Follow-up averaged 23 months(15-38 months). Both the patients' postoperative satisfaction and the postoperative radiographic results were retrospectively evaluated. Results: The duration from applying the external fixator to remove averaged 15 weeks (8-21 weeks). We did osteotomy again in two cases because of early consolidation at the osteotomy site during distraction period. All cases were evaluated mild claw toe deformity and motional pain in metatarsophalangeal joint, but all patients satisfied the postoperative results except one complained motional pain and stiffness in metatarsophalangeal joint. The metatarsal shortening averaged 13mm(9-18mm) before operation. The amount of distraction for shortened metatarsals averaged 15mm(5-22mm). We found the 6 cases of narrowing of the metatarsophalangeal joint, 2 cases of subluxation of the metatarsophalangeal joint. Conclusion: We think that callotasis with external fixator is good operative method for the brachymetatarsia.

      • KCI등재

        신연 관절 성형술을 이용한 족근 관절 골관절염의 치료증

        박용욱,김도영,이상수,임창균,박현철,Park, Yong-Wook,Kim, Do-Young,Lee, Sang-Soo,Lim, Chang-Kyun,Park, Hyun-Chul 대한족부족관절학회 2002 대한족부족관절학회지 Vol.6 No.2

        Purpose: To evaluate the effectiveness of distraction arthroplasty as treatment for moderate or severe ankle osteoarthritis Materials and Methods: Thirteen patients who underwent distraction arthroplasty using the Ilizarov external fixator were available. We removed osteophytes around the ankle before applying the external fixator. We encourage the patients to do active range of motion exercise and to walk with cruch. Follow-up averaged 15 months (range, 10-31 months). Both the patients' postoperative satisfaction and the radiographic joint space were retrospectively evaluated. Results: The duration from applying the external fixator to remove was 12 weeks. Breakage of the wire applied to the forefoot occurred in 2 cases. All patients satisfied with the postoperative clinical results. The ankle joint space averaged $1.6{\pm}0.2mm$ in pre-operative, $4.2{\pm}0.9mm$ in post-Ilizarov external fixator's removal, and $2.3{\pm}0.3mm$ in last follow-up ankle lateral view. Conclusion: We think that distraction arthroplasty with external fixator is useful operative method for the moderate or severe ankle osteoarthritis.

      • KCI등재

        족관절 골관절염에서 히알루론산 관절 내 주사

        박용욱,Park, Yong-Wook 대한족부족관절학회 2011 대한족부족관절학회지 Vol.15 No.3

        Treatment of osteoarthritis of the ankle joint is similar to that of any other large joint and includes conservative and surgical treatments. Surgical option in severe osteoarthritis is joint fusion or joint replacement, whereas conservative treatment is limited and includes mainly ankle supports, physical therapy, and oral medication. Hyaluronic acid was discovered in 1934 and now has been widely used in the knee and shoulder joints. We reviewed the articles about an intra-articular hyaluronic acid injection in the treatment of osteoarthritis of the ankle joint.

      • KCI등재

        동통을 동반한 주상골 부골에 대한 단순 골 절제술과 골 절제 및 후 경골 건 전진술간의 방사선학적 결과 비교

        박용욱,유정한,박홍준,조양범,유선오,이호진,Park, Yong-Wook,Yoo, Jung-Han,Park, Hong-Jun,Cho, Yang-Bum,Yu, Sun-O,Lee, Ho-Jin 대한족부족관절학회 2002 대한족부족관절학회지 Vol.6 No.1

        Purpose: To analyze the radiographic results between the simple bone excision and simple bone excision and posterior tibial tendon advancement for prehallux. Materials and Methods: Thirty-four patients who underwent operative treatment for prehallux between 1995 and 2000 were reviewed. Twenty-six patients who underwent simple bone excision and posterior tibial tendon advancement and eight patients who underwent simple bone excision were available for follow-up. Follow-up averaged 44 months(15-59 months). We evaluated and compared the cuboidal height and the talo-1st metatarsal angle in the preoperative and postoperative radiography. Results: The average span of disappearing pain is 3.7 months(2-7 months) after the operation. Mean cuboidal height and talo-1st metatarsal angle were increased $6.7{\pm}1.8mm$, $5.0{\pm}2.1^{\circ}$ before to $7.8{\pm}0.2mm$, $5.6{\pm}0.7^{\circ}$ after simple bone excision and posterior tibial tendon advancement. Mean cuboidal height and talo-1st metatarsal angle were increased $6.6{\pm}0.7mm$, $4.6{\pm}1.1^{\circ}$ before to $7.7{\pm}0.9mm$, $5.1{\pm}0.4^{\circ}$ after simple bone excision and posterior tibial tendon advancement. One case of extra-osseous migration of the Mitek anchor inserted into navicula was seen during the follow-up period. Conclusion: This study shows that the remarkable differences between the two procedures are not found. So, simple bone excision without advancement of posterior tibial tendon for prehallux can generate relatively good results.

      • SCOPUSKCI등재

        ZnO 압전 박막을 이용한 고주파 SAW 필터 연구

        박용욱,신현용 한국세라믹학회 2003 한국세라믹학회지 Vol.40 No.6

        RF 마그네트론 스퍼터링법을 이용하여 유리기판위에 인가전력 100 W, 1.33Pa, Ar/O2=50 : 50, 20$0^{\circ}C$ 그리고 타겟과 기판사이의 거리 4 cm의 조건으로 ZnO 압전 박막을 성장시켰다. 증착된 박막의 결정성, 표면형상, 화학적 결합비와 전기적 특성을 XRD, SEM, AFM, RBS와 electrometer를 이용하여 측정 분석하였다 제조된 박막은 우수한 c축 우선 배향성을 보였고 또한 화학 양론적인 결합비를 나타내었다. 전극 구조가 single 및 double IDT를 갖는 ZnO/1DT/glass SAW 필터를 제작하여 특성을 분석한 결과, 전파속도는 각각 2,589 m/sec, 2,533 m/sec이었고, 삽입손실은 -11 dB과 -21 dB 값을 나타내어 박막형 SAW 필터로 응용이 기대된다. ZnO thin films on glass substrate were deposited by RF magnetron reactive sputtering at 100 W, 1.33 Pa, Ar/O2=50 : 50, 200$^{\circ}C$, and a target/substrate distance of 4 cm. Crystallinities, surface morphologies, chemical compositions, and electrical properties of the films were investigated by XRD, SEM, AFM, RBS, and electrometer. All films showed a strong preferred c-axis orientation and the chemical stoichiometry. The propagation velocity of ZnO/IDT/glass of single electrode and double electrode types SAW filter was about 2,589 m/sec, 2,533 m/sec and insertion loss was a minimum value of about -11 dB and -21 dB, respectively.

      • KCI등재

        종골 골절후 발생한 족부 구획 증후군의 치료

        박용욱,정영기,유정한,전득수,황필성,Park, Yong-Wook,Chung, Yung-Khee,Yoo, Jung-Han,Jun, Deuk-Soo,Whang, Pil-Sung 대한족부족관절학회 1999 대한족부족관절학회지 Vol.3 No.1

        Eleven patients with calcaneal fracture had 2 acute compartment syndrome of the feet and 9 late complication of the compartment syndrome of the feet. An interstitial pressure of more than 30 mmHg in either the central or interosseous compartment was considered pathologic and was treated by fasciotomy performed medially. Rigid claw toe deformity was treated by excision of the head and neck of the proximal phalanx, dorsal capsular release of the metatarsophalangeal joint, and lengthening of the extensor tendon. Patients were evaluated at a mean of 35 months(range, 21 - 44 months) after operation, and the examination was directed specifically toward symptoms and signs of myoneural ischemia, and walking pain. At follow -up, 2 patients with acute compartment syndrome of the foot had no evidence of myoneural ischemla, 9 patients with claw toe deformity had no pain with walking. Based on our clinical observations, we concluded that compartment syndrome of the foot may occur after the calcaneal fracture and fasciotomy is effective treatment for the prevention of the long term sequelae of this debilitating condition.

      • KCI등재

        통증을 동반한 소아 유연성 편평 족의 수술적 치료

        박용욱,윤태경,정운섭,Park, Yong-Wook,Yoon, Tae-Kyung,Jeong, Un-Seob 대한족부족관절학회 2003 대한족부족관절학회지 Vol.7 No.1

        Purpose: The purpose of this study was to evaluate the result of open wedge osteotomy at the anterior calcaneus with iliac bone graft (Evans procedure) for symptomatic flexible flatfeet in children. Materials and Methods: A retrospective study was conducted between October 1995 and September 2002. Six cases in 3 patients who had symptomatic flexible flatfeet was included. Follow-up averaged 39.5 months. We evaluated the patients' satisfaction by Mann and Reynolds scorring and compared the radiographic results between preoperative and final radiography. Results: The satisfaction outcomes at the last follow-up were excellent in five and good in one. The mean lateral talo-first metatarsal angle was improved from $-20^{\circ}$ to $-3^{\circ}$. The mean calcaneal inclination angle was improved from $8.5^{\circ}$ to $20.8^{\circ}$. The talo-navicular coverage angle was improved from $47.5^{\circ}$ to $7.5^{\circ}$. In one case, we found the subluxation of calcaneocuboidal jont in postoperative radiography. Conclusion: Open wedge osteotomy at the anterior calcaneus for symptomatic flexible flatfeet in children was considered as one of the effective treatment methods.

      • KCI등재

        족근 골 결합의 수술적 치료

        박용욱,윤태경,정운섭,Park, Yong-Wook,Yoon, Tae-Kyung,Jeong, Un-Seob 대한족부족관절학회 2003 대한족부족관절학회지 Vol.7 No.1

        Purpose: The purpose of this study was to evaluate the results of surgical treatments for tarsal coalitions. Materials and Methods: A retrospective study was conducted between October 1995 and September 2002. Four cases of talocalcaneal coalitions and two cases of calcaneonavicular coalitions were included. We did bone excision for three cases of talocalcaneal coalitions and two cases of calcaneonavicular coalitions. In one case of talocalcaneal coalition, we did subtalar fusion. Follow-up averaged 43 months. We evaluated both the patients' satisfaction rates by Mann and Reynolds scorring and compared the radiographic results between preoperative and final radiography. Results: The satisfaction outcomes at the last follow-up were two excellent and two good in talocalcaneal coalitions and all excellent in calcaneonavicular coalitions. Two cases of talocalcaneal coalition who did excision of coalition complained mild pain in hindfoot, however, symptoms improved than preoperation. In calcaneonavicular coalition, pain is subsided at mean post-operative 13 weeks. During follow-up period, there were no radiographic changes and recurrence in all cases. Conclusion: In small cases, we think the cause of subsidence of symptoms maybe reconstruction of normal joint motion after excision of tarsal coalition. But, we try to warn the patients with talocalcaneal coalition that the symptom may not be completely subsided after the excision of coalitions.

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