단일병원에서 관찰한 최근 10년간의 소아 우발사고에 관한 연구 : 이물흡인을 중심으로

김철민,송준영,김자형,김기수,홍수종 대한소아과학회 2002 小兒科 Vol.45 No.9

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

2,4,6-Trinitrobenzenesulfonic acid 반응에 의한 효소 활성도 측정

김수자,이승주 慶熙大學校 1983 論文集 Vol.12 No.-

A new simple assay method for the peptidyl-dipeptide hydrolase using 2, 4, 6-Trinitrobenzenesulfoic acid was developed and optimum conditions were determined. At the condition studied, this assay was found to be more sensitive than other spectrophotometric methods.

미국내 한국현대사 자료 연구 : 美 국립문서기록관리청 Record Group 263의 NIS, FBIS를 중심으로 On the NIS, FBIS at Record Group 263 in the National Archives

김수자 이화사학연구소 2003 梨花史學硏究 Vol.0 No.30

Record Group 263 are the report written by the CIA(Central Intelligence Agency) of USA. Those were reported by the USA with purposes of sustaining their strength in the world, so that those reports are excellent in the phase of data collection and analysis. The outstanding reports of RG 263 about Korea are the National Intelligence Survey(NIS), Office of Research Estimate(ORE) and succeeded by National Intelligence Estimate(NIE), and Foreign Broadcast Information Service(FBIS). Those reports are possessed in the National Archives Ⅱ of Maryland, USA. NIS were the worldwide survey and analysis report between 1950s and 1960s. Those information broadly covered on the polities, geography, industry, military, and social affairs. The main items woe similar to in every country, but topics were a little bit different by the national characteristics and events development method. The NIS were focused on the survey of Military Capability and it Natural Environment. The sample topic of the NIS were political system, health and sanitary, weather and climate change, communication systems, economics, armed farces, and military maps. ORE were reported 150 articles from 1946 to 1950 by CIA. Those papers are similar to NIE at basic system and contents of survey. However ORE report focused on the characteristics of estimation and has been classified f the Agency's historical review program of the CIA. FBIS had several types like daily reports, weekly reports and abstracts. Those contains broadcasting messages and summaries from communist country from 1941 to 1974, and basic type is the daily reports. The amounts of these reports are so huge that the size of FBIS stacks is 247㎥.

Glutamate-Glutamine 변환반응에서의 ATP 재생산계에 관한 연구

김수자,한지영 慶熙大學校 1993 論文集 Vol.22 No.-

The conversion of glutamate to glutamine by glutamine synthetase was studied using ATP regenerating system which is consisted of coupled pyruvate kinase-phosphoenolpyruvate system and immobilized ATP. Two new bioactive polymeric ATP analogs, poly-glycidylmethacrylate-ATP and copoly-glycidylacrylate-N-vinylpyrrolidone-ATO were synthesized and were found to be regenerated efficiently in glutamine synthetase-pyruvate kinase regenerating system. Optimum conditions for the Glu-Gln conversion using ATP regenerating system were established and extended applications of synthetic polymeric coenzyme derivatives in the continuous synthesis of useful substances in membrane bioreactor were suggested.

돼지 비장으로부터 Peptidylprolyl cis-trans Isomerase의 정제와 특성에 관한 연구

김영옥,김수자 慶熙大學校 1998 論文集 Vol.27 No.-

A peptidylprolyl cis-trans isomerase(PPIase) was isolated and purified from porcine spleen cytoplasm using two consecutive Sephadex G-75 gel filtration chromatography, CM-trisacryl M cation exchange chromatography and fast protein liquid chromatography(FPLC). Purified porcine spleen PPIase was electrophoretically homogeneous and the specific activity was 131 fold higher as compared to that of crude extract. The molecular weight of the enzyme determined by SDS-PAGE was ∼14,000 daltons. Upon isoelectrofocusing the enzyme showed the pI of 8.9. Porcine spleen PPIase was assayed with satisfaction by the PPIase-chymotrypsin coupled assay method. The enzyme actiyity was markedly inhibited by FK506 at nanomolar concentration but not by cyclosporin A indicating that the enzyme is a kind of FKBP type immunophilin rather than a cyclophilin. The first fifteen N-terminal amino acid residues of porcine spleen PPIase was found to be G, V, Q, V, E, T, I, S, P, G, D, G, R, T, F. There is complete homology between porcine spleen PPIase and FKBP-12 in their N-terminal amino acid sequences.

성인에서 발병한 지역사회폐렴의 원인으로서 호흡기 바이러스의 역할

김지희,곽영호,나병국,이주연,신구철,정혜선,홍정연,오명돈,정희진,김민자,배현주,김양리,신완식,강재명,우준희,어수택,이환종 대한감염학회 2001 감염 Vol.33 No.1

Purposes : To investigate the viral etiology of community-acquired pneumonia in Korean adults, we have detected respiratory viruses (Respiatory syncytial virus, adenovirus, influenza virus and parainfluenza virus) in the way of prospective, multi-center study. Methods : From July 1997 to April 2000, nasal aspirates or sputum were obtained from adults patients with community pneumonia admitted to the participating hospitals and transferred immediately to the central laboratory at the Seoul National University Children's Hospital. The specimens were divided into three parts. One part was used for indirect immunofluorescent test for respiratory viruses, the other part for the culture of RSV and adenovirus in HEp-2 cell monolayer. The other part was used for the culture of influenza virus and parainfluenza virus in MDCK or LLC-MK2 cell monolayers. Results : Of 317 samples, 32 (10.1%) specimens were positive for viral agent by indirect IF staining or culture, including one dual-infected specimen (adenovirus and parainfluenza virus). Influenza virus was most commonly detected (16 specimens). Parainfluenza virus, adenovirus and RSV were detected in 10, 4 and 3 patients, respectively. All isolated influenza viruses were type A (H3N2 in 9 patients, HIN1 in 2 and unspecified in 5), and 8 out of 10 parainfluenza virus isolates were type 3. Conclusion : Similar to previous reports from other countries, a significant portion of community-acquired pneumonia in Korean adult is caused by respiratory viruses. (Korean J Infect Dis 33:8~14, 2001)

Glucocorticoid가 비장세포 임파구의 증식,Interleukin-2(IL-2) 생산 및 말초 혈액 임파구의 IL-2수용체 발현에 미치는 영향

김정목,조양자,이수영,박장환 漢陽大學校 環境科學硏究所 1992 環境科學論文集 Vol.13 No.-

Glucocorticoids are widely used as therapeutic agents in as variety of allergic and inflammatory diseases and in transplantation rejection. Although glucocorticoids are thought to influence on the immunologic reation, they are not fully known to influence on the immune cell function. In this report, we have studies effects of glucocorticoid. dexamethasone, on porliferation and production of interleukin-2(IL-2) in mouse splenic lymphocytes and on expression of IL-2 production, we isolated C57BL6 mice splenic cells and stimulated with Con-A(5㎍/ml). As the concentration of dexamethasone was increased, the proliferation and the IL-2 production of mouse splenic lymphocytes stimulated by Con-A (5㎍/ml) were decreased. And the expression of IL-2 receptors in human peripheral blood lymphocytes was also decreased in addition of dexamethasone. These findings suggest that proliferation, IL-2 production, and IL-2 receptor expression of immune cells are inhibited by glucocorticoid, dexamethasone.

개구부 보강철근의 배근방법이 고강도 철근콘크리트 깊은 보의 전단거동에 미치는 영향

김자영,김광두,양근혁,정헌수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The purpose of this experimental study is to understand the effect of configuration of web opening reinforcement on the shear behavior of reinforced high-strength concrete deep beams with rectangular opening. The configuration including the vertical, the horizontal and the diagonal web opening reinforcements are considered as main variable. The test specimens shaped over-all depth of h 60cm, width of b 16cm and length of L 240cm were made of 8 simply supported high-strength concrete deep beams and the size of the web opening is fixed by 0.5a×0.3h. The test results show that diagonal web opening reinforcement comparing both vertical and horizontal reinforcements is the most efficient in restricting the diagonal crack width development and enhancing the shear capacity.