화상 환자에서 파상풍 예방치료에 대한 조사

탁석현,유기철,이삼우,강민수,오승헌,안무업,안희철,조준휘,박우정 대한화상학회 2003 대한화상학회지 Vol.6 No.2

間歇的 運動에 의한 脫水 및 水分攝取의 生理的 效果

朴哲浩,朴吉俊,李相于,金永明,朴贊熙,玄松子,呂南會,朴相甲,金榮俊 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

This study aims at revealing the physiological responses of dehydration (DH) and rehydration (RH) in intermittent exercises at the work intensity of 70% HR max. First, with general student public, three times of exercise (each for 20 minutes) at the given work intensity were taken, with a break for 25 minutes respectively. Their heart rate, rectal temperature and plasma electrolyte concentration both DH and RH were measured. Second, in two groups of athletes and non-athletes, 9 rounds of exercise (for 100 minutes) and 8 breaks (for 60 minutes) were taken, with RH forced 10 times to compensate for the subjects' water loss. Their change in sweat loss and plasma electrolyte concentration as well as the IVDP(Intensive Voluntary dehydration Phenomenon) were experimented. The summary of this research follows. 1) Mean heart rate and rectal temperature in intermittent exercises were higher at DH than at RH, growing up at the increasing level of DH. 2) RH saw no change in the plasma concentration of Na+, K+ and Cl-, while DH observed a significant increase. 3) HCO₃made a significant decrease at DH before growing up. 4) Mg++ had no change, while Ca++ increased significantly at RH and DH. 5) Lactate showed an increase with significance at RH and DH, especially greater at DH. 6) Osmotic pressure increased meaningfully at DH. 7) Anion gap increased significantly at DH and RH. 8) On the other hand, when the forced RH was held, the group of athletes had greater sweat loss per body surface area than that of non-athletes. 9) The athletes' plasma concentration of Na+ and Cl- revealed a clear decrease. 10) There was seen no significant change in the plasma concentration of K+, Mg++ and Ca++ in both groups. 11) The IVDP occurred at the RH of 2.3ℓfor athletes and more than 2.5ℓfor no-athletes.

단무지 공장에서 발생한 질식 사고의 원인과 방사선학적 소견: 중례보고 및 가스분석 결과

박충기,김만구,김흥철,안범규,박만수,황우철,최철순,강익원 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

목 적:단무지 공장에서 질식사고를 일으켰던 가스의 종류를 알아내고, 이러한 가스중독의 방서선학적 소견을 소개하기 위하여 본 연구를 하였다. 대상 및 방법:단무지 공장에서 발생한 질식 사고자 3예중 생존자 1예를 대상으로 단순흥부X-선검사와 CT 소견을 분석하였으며, 가스의 종류를 알아내기 위하여 단무지를 유리병에 넣어 발생된 가스를 가스크로마토그래픽을 이용하여 분석하였다. 결 과:단무지 공장에서 발생한 질식사고자중 생존한 1명의 방사선학적 검사에서 신속히 호전되는 폐경결(consolidation)을 볼 수 있었으며 이는 폐부종의 소견임을 알 수 있었다. 협기성 상태에서 단무지를 담은 유리병의 상층부 가스를 실험 분석한 결과 이산화탄소, 에칠알코올이 다량으로 검출되었으나 독성가스는 주로 황화수소이였다. 결 론:단무지 공장의 질식 사고자에서 폐방사선학적 소견은 폐경결을 보이는 폐부증으로서 이는 실험을 통해 단무지에서 발생되는 유독가스인 황화수소 때문임을 입증하였다. Purpose: To identify the main toxic gas released from salted radish in rice bran(Dan-M-Ji) and to introduce the radiological findings of the patient who was exposed to the gas. Materials and Methods: Chest radiographs and CT scans of one survivor among three men who were exposed to the gas from Dan-Mu-Ji were reviewed. Gas obtained from the closed bottle containing Dan-Mu-Ji was analized by using the gas chromatography. Results: The radiographlc examinations of the survivor were suggestive of pulmonary edema with it's rapidly improving consolidations in both lung. The headapace gas within the bottle containing Dan-Mu-Ji was mainly composed with carbon dioxide, ethyl alcohol and hydrogen sulfide, of which hydrogen sulfide was considered the main toxic gas released. Conclusion: Under the anaerobic condition, Dan-Mu-Ji released toxic hydrogen sulfide. Inhalation of hydrogen sulfide might produce non-cardiogenic pulmonary edema.

하악과두 골절 치료에 있어 보존적 치료와 외과적 치료의 비교

박인순,이철우,여환호,이효빈,김영균,변웅래 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

The authors investigated the 17 patients with the condylar fractures of the mandible who were admitted in Dept. of Oral and Maxillofacial Surgery, Chosun University, Dental hospital from 1990 to 1993 and could be taken follow-up above 6 months. Helkimo's clinical dysfunction index and mandibular mobility index were applied to the evaluation of the patients and the obtained results were as follows. 1. Mean maximal mouth opening was 38.4mm in the conservative group, 41.3mm in the surgical group and that showed no statistically significant difference.(P>0.05) 2. Clinical dysfunction index was higher in the surgical group than in the conservative group but .that showed no statistically difference.(P>0.05) 3. The extent of maximal mouth opening was increased gradually throughout the follow-up period. 4. Both groups didn't show severe clinically dysfunction.

휘발성유기화합물(VOCs)의 변이원성 검정

박종천,이용탁,송현철,이우범 國立麗水大學校 環境問題硏究所 2004 環境硏究論文集 Vol.6 No.-

The mutagenicity of six kinds of VOCs(benzene, m.p-xylene, chloroform, toluene, methylethylketone, 1,2-dichloroethane) detected in high concentration and frequency in Kwangyang Bay was investigated. VOCs are water-insoluble and volatile. Therefore, when they are tested by the classical Ames test in the assay of mutagenicity, there may be experimental errors. To overcome this limitation, modified Ames test was used to assay mutagenicity of VOCs. By this modified Ames test, we could obtain much more satisfactory results. Even at extremely low concentration(0.0001㎍/㎖). bezene, m,p-xylene, and methylethylketone showed a weak mutagenicity. When S-9 mixture is added in the assay system, all tested VOCs except methylethylketone showed mutagenicity. When Salmonclla typhimurium TA 98 and Salmonella typhimurium TA 100 are exposed to VOCs of high concentration(100㎍/㎖). the number of colony decreased irrespective of the S-9 mixture treatment. It seem to be that the decrement results from the toxic effect of high concentration of VOCs.

당뇨병성 다발성 신경병증에 대한 Thioctic acid의 유효성 및 안정성에 관한 연구

박철영,김영설,오승준,우정택,김성운,양인명,김진우,최영길 대한당뇨병학회 2001 임상당뇨병 Vol.2 No.1

연구배경: 당뇨병성 신경병증은 당뇨병 환자에서 흔히 나타나는 합병증으로서 임상 증상은 가볍거나 없을 수도 있지만 많은 경우에 통증, 작열감, 이감각증이나 무감각증 등의 증상을 동반하지만, 이에 대한 명확한 기전이나 뚜렷한 치료방법이 없었다. 최근에 신경세포내 산화성 스트레스의 증가로 신경세포의 손상이 발생된다는 기전이 주목을 받으면서, 당뇨병성 신경병증 환자에게 항산화제인 thiotic acid를 사용하여 좋은 효과를 관찰한 논문들이 발표되었다. 이에 저자들은 한국의 당뇨병성 다발성 신경병증 환자에서 thiotic acid를 경구 투여 후에 신경병증에 의한 효과 및 안정성을 평가하였다. 방법: 모든 대상 환자에게 Thioctic acid 600㎎ 을 1일 1회 아침 식전 30분에 8주간 투여하여 당뇨병성 다발성 신경병증에 대한 TSS의 개선여부에 대한 임상적 유효성 및 이상반응, 내약성, 실험실적 지표의 변화를 통한 안정성을 관찰하였다. 결과: 치료시작 전에 관찰한 환자가 호소하는 증상은 통증이 가장 많았으며 무감각, 작열감, 이상감각 순의 빈도를 보였다. 통증, 작열감, 이감각증, 무감각증의 평균 TSS는 1차 방문시 5.8± 1.8, 2차방문시는 4.4±1.7, 3차 방문시는 3.1±1.1로 사용기판에 따라 통계학적으로 유의한 증상의 호전이 있었다. 또한 TSS의 개선 뿐만 아니라 통증, 작열감, 이감각증 및 무감각증 각각의 증상도 치료전과 치료 4주 후 및 치료 8주 후를 비교했을 때 통계학적으로 유의한 증상의 호전이 있었다. TSS가 1차 방문 시와 비교했을 때 3차 방문시에 30% 이상 개선되었을 때(1차 방문시에 TSS 4인 환자는 2점 이상 개선되었을때) 임상적으로 의미가 있는 반응으로 간주하고 계산한 반응률은 71.3%였다. 결론: 당뇨병성 다발성 신경병중 환자에 대해 항 산화제인 thioctic acid 600㎎ 경구 투여요법은 당뇨병성 신경병증의 증상완화에 유용하며, 안전한 것으로 사료된다. Background: The study was peformed to evaluate the efficacy and safety of oral treatment with the antioxidant α-lipoic acid (Thioctcid??) in diabetic patients with peripheral polyneuropathy. Methods: Thioctacid?? 600㎎ was orally administered once a day for 8 weeks in 61 diabetic patients with peripheral polyneuropathy. Neuropathic symptom(pain, burning, paresthesia, and numbness) were scored before, and of 4 and 8 weeks after treatment. In addition, neuropathy by the physician and patients at the end of treatment. The primary endpoint was the response role after 8 weeks treatment, defined as an improvement in the total symptom score of at least more than 30%. Results: Efficacy was evaluated among forty-four patients who had completely the study according to the protocol and safety was evaluated among all of 61 patients who had taken the study medication. The response rate after 8 weeks was 77.3%. The total symptom score was significantly decreased of 4-week, and further decreased of 8-week. All the individual scores for neuropathic symptom were also significantly reduced of 4-week and further decreased at 8-week. Conclusion: These finding indicate that oral treatment with thioctacid?? at a dose of 600㎎/day for 8 weeks will improve peripheral polyneuropathy in diabetic patients, without causing any serious adverse events.

폴리에스터 연속 중합 공정의 전산모사 연구

박융호,강우철 漢陽大學校 工學技術硏究所 1999 工學技術論文集 Vol.8 No.1

Process modeling, though a very useful tool in optimizing chemical processes, is not utilized very much in Korea due to lack of modeling techniques and application experiences. Modeling of the complicated processes haven't been attempted very much due to the difficulties in using the process simulator and the lack of actual experiences in optimization of large processes. In the case of continuous process of PET polymerization, the modeling of the entire process has never been reported due to secret of commercial processes. In this works, a model for PET process has been bullit with a commercial simulator(Aspen Plus) with a detailed consideration of undissolved TPA particles in esterification step and mass transfer of EG in polycondensation step. The model was used in investigating the effect of the changes in the operating conditions of the process on the properties of polymer product and in studying the interaction among the process equipments. And practical techniques for process modeling and optimization have been suggested through the example of PET process modeling.

측두하악관절 내장증에서의 관절원판의 형태 및 골 변화에 관한 연구

박철우,황의환,이상래 대한구강악안면방사선학회 2001 Imaging Science in Dentistry Vol.31 No.1

Purpose : To investigate bone and disc configuration on MR images in internal derangement related to age. Materials and methods : MR images of 150 TMJs in 107 patients were analyzed to determine the morphologic changes. Two groups were distinguished to be correlated with age. Group 1 consisted of TMJs that were diagnosed as having anterior disc displacement with reduction (ADDwR), and Group 2 consisted of TMJs that were diagnosed as having anterior disc displacement without reduction (ADDwoR). We assessed the configuration of the articular disc, degree of anterior disc displacement, and osseous changes of TMJs. Results : The third decade (83 of 150 joints) was most frequent in this study. In the ADDwR group biconcave discs was most frequent at all ages except fifth decade, but in the ADDwoR group deformed discs was most frequent at third and forth decades. In the ADDwR group slightly displaced discs was most frequent at all ages, but in the ADDwoR group severely displaced discs was most frequent at second decade, and the degree of disc displacement was increased with aging over 30 years of age. TM joints showed osseous changes in 17% of the ADDwR group, and in 30% of the ADDwoR group. MR findings of osseous changes of the TMJ were not found to be significantly correlated with age. Conclusion : The prevalence of deformation of disc, displacement of disc, and osseous changes of TMJ was higher in the ADDwoR group than in the ADDwR group. MR findings of disc configuration and degree of disc displacement were found to be correlated with age.(Korean J Oral Maxillofac Radiol 2001;31:9-16)

광파이버 변위센서 성능에 관한 연구

박찬규,신우철,홍준희,김기수 충남대학교 공업교육연구소 2003 論文集 Vol.26 No.1

The purpose of this paper is to develop an optical fiber displacement sensor. An optical fiber displacement sensor is based on simple principles. Electrical signal responds to the optical flux change due to the displacement change between a target and a sensor probe. In this paper, the performance of optical fiber displacement sensor has been investigated. Firstly, optical loss has been measured before and after polishing optical fiber endface. Secondly, allowance of optical fiber bending has been tested. Thirdly sensitivity and linear range of the sensor has been found out according to the shape of cross section of optical fiber.

승강대 운동이 비만고등학생의 혈청 지질 및 아포지단백 대사에 미치는 영향

박철호,고봉민,박은경,우상헌,안민호 동아대학교 스포츠과학연구소 2000 스포츠科學硏究論文集 Vol.18 No.-

The purpose of this study was to investigate the effect of 12 wks before and after step test of obsese student in D high school in Pusan city, exercise group(7) performed 12 wks step test and control group(7), before and after subjects performed the maximal exercise thest on treadmile's 12 wks step test. Through the comparision and analysis of change serum lipids and apolipoprotein metabolism, the results of this study were as follows. 1.In 12 wks before and after step test at the rest time, exercise group was found to have a increase In TC(12.7%), TG(9.76%), LDL-C(13.8%) and to have a significant increase in HDL-C(11.3%), FFA(96.8%). 2.At the rest, the control group was found to have a little increase in TG(9.2%) and HDL-C(6.7%), and to have a significant increase in TC(9.2%), LDL-C(8.9%) and FFA(7.5%). 3.In 12 wks before and after step test at the maximal exercise, the exercise group was found to have a significant increase in TC(5.6%), HDL-C(20.2%) and FFA(54.3). 4.At the maximal exercise, were found to have a significant increase in TC(9.7%) and LDL-C(9.9%) in the control group. 5.In 12 wks before and after step test at the maximal exercise, the exercise group was found to have a significant increase in Apo A-I(8.0%). 6.Statistically, At the maximal exercise, were found to have a significant increase in Apo B(7.8%).