다발성 외상환자에서 필수적 단순 방사선검사의 의의

임경수,황성오,임종천,이부수,이강현,이진웅 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

In the guidelines of Advanced Trauma Life Support(ATLS), essential plane roentgenograms (chest AP vIew, cervical spine lateral view and pelvis AP view) are recommanded when primary survey and resuscitation phase are finished in care of multiple injured patients. A prospective study was carried on 376 multiple trauma patients who admitted to Wonju Christian Hospital from July, 1995 to October. We analyzed clinical significance of essential X-ray in multiple trauma patients, and classified the patients by their status of mentality. The one is alert group when their Glasgow Coma Scale(GCS) is over 13 point, the other is disoriented mentality group when their GCS are below 12 point. The alert group was redivided by presence of clnical symptoms and/or signs, and clinical significances of essential X-ray were analyzed. Among the 376 patients, 330 patients are alert group that their GCS score is over 13 point and 46 patients are disoriented group who's GCS were below 12 point. The detection rate of abnormality in essential X-ray is higher in disoriented group than alert group(cervical-spine lateral view : 13.5% vs 3.0% cheat AP view : 0.4%, pelvis AP view : 0%). This study suggests that their are no needs of taking essential X-ray in patients who is alert in mental state and have no clinical symptoms and/or signs.

알루미늄 튜브 하이드로포밍에서의 예비 굽힘 공정의 효과에 관한 연구

임희택,박경창,김형종,김헌영 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.B

Recently social demands of fuel economy and environmental regulations require the development of lightweight components and new manufacturing technologies. The aluminum tube hydroforming is a manufacturing process which can provide lightweight components as automotive parts. In this paper, the hydroformability of aluminium tube in different condition of bending process is presented. An investigation has been conducted on how to control the deformed shape and its effect on thinning distribution after hydroforming by using finite element simulation. Finite element simulation of tube hydroforming for automotive trailing arm is carried out to explore the effect of 2-dimensional and 3-dimensional bending.

액체크로마토그래피/질량분석법을 이용한 랫트 혈장내의 Surfactin C의 정량법에 관한 연구

임종환,김명석,이동연,이상훈,백경진,김태원,정두순,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Surfactin isolated from Bacillus subtilis has a strong surface tension-lowering activity, together with antiviral, antitumor, fibrinolytic and hypocholesterolemic activities. LC/MS is a simple, rapid and effective technique for the determination of surfactin C in rat serum. The separation of surfactin was achieved on reverse phase column. The mobile phase consisted of 0.1% trifluoracetic acid in water (A) and acetonitrile (B). As a result of analysis of blank rat serum samples, matrix interference was not shown. The values of precision and accuracy were satisfied w the guideline. A newly developed LC/MS method for the determination of surfactin C was successfully applied in its pharmacokinetic analysis.

Pyriminobac-methyl과 azimsulfuron 합제의 신규제형인 분산형 정제에 대한 독성 평가

백경진,이동연,이상훈,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Dispersible tablets disintegrate either to form a stabilized suspension rapidly in water, or to disperse instantaneously in the rice field without the aid of water. In this study, the newly formulated dispersible tablet form of herbicidal combination, pyriminobac-methyl and azimsulfuron, was evaluated the safety for human and animals in the toxicological viewpoints. The LD_(50) value of dispersible tablet form for pyriminobac-methyl and azimsulfuron was above 2,500 mg/kg for the oral route and above 2,000 mg/kg for the dermal route. It is considered to have low acute oral and dermal toxicity based on the findings of the present studies. In addition, the combination of pyriminobac-methyl and azimsulfuron showed mild skin irritant under the conditions of this study and conjunctival redness and slight opacity on cornea appeared from 1 hour after application.

RAW264.7 세포에서 interferon-r 및 LPS에 의해 유도되는 NO생성에 미치는 TALT-35의 영향

박종일,박경석,김종석,박지훈,윤은진,송경섭,서강식,김훈,윤완희,박승길,임규,황병두 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

TALP-35 purified from human term placenta is known to increase microtubule polymerization and stabilize the polymerized microtubule. To examine the effect of TALP-35 on immune system this study was performed. MTT assay was performed to investigate the effect of TALP-35 on the proliferation of RAW264.7 cells. TALP-35 dose dependently suppress the proliferation of RAW264.7 cells at high concentration (above 1 μM) in unstimulated cells, in case of 10 μM TALP-35 treated cells the suppression was 25% but in stimulated cells it was only 15%. Cosedimentation assay was carried out to investigate whether TALP-35 can bind to tubulin of RAW264.7, monocyte/macrophage lineage of mouse, and polymerize it. TALP-35 polymerize the tubulin of RAW264.7 cells and sedimented in dose-dependent manner. To investigate the effect of TALP-35 on the expression of iNOS protein western blotting was performed. The expression level of iNOS was decreased dose dependently in high concentration of TALP-35 treatment. To examine the activity of iNOS, secreted NO was determined by method based on Griess reaction. Interferon-γ and LPS-stimulated production of NO from RAW264.7 cells was decreased dose dependently above 0.1 μM concentration of TALP-35 and 50% is decreased at 10μM of it. This study shows TALP-35 can control cytokine induced-iNOS expression therefore it might control inflammatory diseases.

GIS를 이용한 산사태분석에 관한 연구

申桂種,林敬洙 충주대 산업과학기술연구소 2001 産業科學論文集 Vol.9 No.-

Every year, landslides hazard of all countries in the world are appeared to given the human race and economic damage. In this study, analyzed landslide hazard risk using GIS is divided by two factors of geo-environmental & natural. GIS analysis about estimate landslides hazard area applied vary effective.

통합 통신망 관리 시스템 구축 방안 연구

이종근,임미경,이광휘,김한경,김태수 國立 昌原大學校 精報通信硏究所 1998 精報通信論文集 Vol.2 No.-

This paper presents a system for internetworking between different network management protocols. The internetworking system between SNMP(Simple Network Management Protocol) and CMIP(Common Management Information Protocol) has been designed. SNMP has been used as a standard protocol in Internet while CMIP has been selected as management protocol in OSI network. This approach is different from previous researches which convert protocols between management protocols. We have newly defined manage objects structure. Thus, even if a new management protocol would be introduce in addition, the new gateway system needs not be designed. We can achieve it through minimum modification in the interface of the managed objects. So, we can support managed objects defined previously using MOVI(Manage Object View Interface) concept presented in our previous research. Through this research, we have some additional benefits: it is able to internetwork between more complicated network management protocols, to increase usefulness of SNMP and CMIP, also it will use in internetworking between new network management protocols.

스키손상에 대한 임상적 고찰

김현,임종천,임경수,황성오 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

We evaluated 1,743 patients with ski injuries who visited to the emergency room located in the Young Pyung Ski Resorts from Nov. 25, 1995 to Mar. 31, 1996. Among the patients, 971 patients were male and 772 were female. In age distribution, young patients from 21 to 30 years old were most common. 44.8% of ski injured patients were admitted on weekend, and 73.2% were on sun-shiny day. The most common injury mechanism was slip-down(65.5%). Among the many prevention methods of skin injury such as physical preparation prior to the skiing season, safe equipment, correcting skiing technique, consideration for other slope users and adaptation to the snow condition, etc., this survey revealed that the avoidance of a cold start is important. Simple injuries such as abrasion, contusion and simple laceration were most common as 66.0%, followed by ligament injuries(19.5%). There were 4 serious injured patients(ISS 16) who were injured by colliding with either moving subject or obstaticles along the ski slopes. Among 4 patients, 1 patients was severe head injury and died, 1 patient was spinal injury and pneumothorax, and 2 patients were hemoperitoneum. Severe injured patients are all beginning skiers and they were injured at a slope for beginning skiers. Certainly, the result of this study would indicate that skier`s experience such as total number of days skied and self-assessed ability, correlated with the risk of injury. Emergency post should be locate at the slope for beginning skiers and/or intermediate skiers, and the medical equipments for emergency care of shock, head injury, spinal injury and chest injury must be equipped at post.

석유화학공장 근로자에서 발생한 재생불량성 빈혈 1례

박영만,임영,강성규,김지홍,이종욱,최용휴,김경아 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

Aplastic anemia is characterized by pancytopenia with hypocellular bone marrow. Fifty percent of the cases are idiopathic and the rest are caused by various agents including drugs, chemicals, radiation and viruses. It is difficult to link specific etiologic agents, especially chemicals to the development of aplastic anemia because multiple or unknown exposures may be involved in. Benzene, a common industrial chemical and a component of gasoline, may lead progressively to pancytopenia, aplastic anemia and leukemia when exposed. A petrochemical worker with aplastic anemia was referred to our hospital to evaluate a relationship between the job history and the disease. He worked in the petrochemical plant for 21 years and was exposed to low-level benzene. There was not anyother etiologic agent except benzene and this is the case report of aplastic anemia which possibly due to benzene exposure.

원주지역에서 발생한 비외상성 심정지의 일주변화

박금수,김영식,이진응,임종천,이강현,임경수,황성오,최경훈 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

To estimate the quality of the emergency medical services system of Wonju City, we studied the diurnal variations of 179 non-traumatic cardiac arrest victims who received cardiopulmonary reuscitation at the emergency center of Wonju Christian Hospital. Diurnal variations of non-traumatic cardiac arrest patients were as follows ; The occurence of cardiac arrest at day-time was higher than night-time; 18 cases (11%) from midnight to AM 4, 25 cases (14%) from AM 4 to AM 8, 42 cases (24%) from AM 8 to AM 12, 46 cases (25%) from AM 12 to PM 4, 35 cases (19%) from PM 4 to PM 8, 13 cases (7%) from PM 8 to midnight. Witness cardiac arrest was increased more during the day than night ; 40% from midnight to AM 4, 48% from AM 4 to AM 8, 57% from AM 8 to AM 12.52% from AM 12 to PM 4, 60% from PM 4 to PM 8, 38% from PM 8 to midnight. The transportation time at night-time cardiac arrest was more longer than day-time cardiac arrest ; 30±12mins from midnight to AM 4, 26±9mins from AM 4 to AM 8, 27±12mins AM 8 to Am 12, 25±11mins from AM 12 to PM 4, 25±9mins from PM 4 to PM 8, 35±15mins from PM 8 to midnight. The rate of restoration of spontaneous circulation(ROSC) in day-time cardiac arrest was higher than the night-time cardiac arrest ; 30% from midnight to AM 4, 36% from AM 4 to AM 8, 32% AM 8 to AM 12, 44% from AM 12 to PM 4, 41% from PM 4 to PM 8, 15% from PM 8 to midnight. The survival rate of cardiac arrest has been correlated with collapse time, early bystander CPR, early advanced care. To improve outcome for prehospital cardiac arrest, we concluded that early bystander CPR, and early advanced life support should be performed at the scene and during the transportation especially at night.