KAERI 부지 주변의 환경선량 측정을 위한 온라인 감마선량 감시시스템

이정호,박두원,이원윤,이현덕,최용호,김삼랑,홍광희,이창우 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.2

환경감마선량 변동을 감시하기 위해 한국원자력연구소 부지 주변에 온라인 감마선량 감시망을 구성하였다. 모니터링 포스트에 설치된 전리함 검출기에 의해 측정된 자료는 무선전송방식으로 중앙통제소에 전송되어 실시간으로 감시된다. 무선전송 방식은 자료의 전송, 처리 및 자자에 신뢰도가 높고 경제적이었다. 감시시스템은 급격한 선량증가시 조기경보체제와 연결할 수 있게 하였다. On-line gamma monitoring system around KSERI-site was set up to monitor the radiation fluctuations in environment. Data on gamma exposure rates measured by the ionication chamber in the monitoring posts are transmitted to a computer of central control station with radio telemetry transmission and reliable on handing and storing of data. This monitroing system can triger an early warning system in the event of abnormal radiation levels.

백혈병 세포중 대한(±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

Using the colorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT)assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine (VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin (Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (±)-ar-turmerone and the extracts of the crude drugs {Lithospermum erythrorhizon(LE) and Scutellaria baicalensis (SB)} on the above mentioned anticancer drugs against HL-60 and KG-1 cells among 8 anticancer drugs, VCR, VBL, ADR, and CPDD inhibited the growth of both cell lines by more than 50%, while VP-16, ara-C, Bleo, and CYC were less effective. (±)-ar-Turmerone had significant inhibitory effects against both cell lines, showing the ID_(50) values of 11.730 μg/ml and 0.292 μg/ml for HL-60 and KG-1 cells, respectively. But the extracts of LE and SB roots showed no significant cytotoxic effects. According to ID_(50) values, the cytotoxicities of VCR, VBL and ADR against HL-60 were enhanced two, eight and three times by mixing (±)-ar-turmerone, five, seven and three times by adding the extract of LE root, and twenty, six and three times by mixing the extract of SB root, respectively. The cytotoxicities of the above mentioned drugs against KG-1 cell were enhanced two, seven and three times by mixing (±)-ar-turmerone, two, three and three times by combining wilth the extract of LB root, and two, five and two times by adding the extract of SB root, respectively. The cytotoxicity-potentiating effects of (±)-ar-turmerone and the extracts of LE and SB roots against HL-60 cell were greater than KG-1 cell.

언어적 창의력 프로그램 개발 연구

이삼형,유영희,권순각 국어교육학회 2004 國語敎育學硏究 Vol.19 No.-

국어과 창의력은 언어적 창의력으로 구체화될 수 있으며, 언어적 창의력은 표현과 이해의 과정 전반에 걸쳐 두루 나타나고 있음을 알 수 있다. 언어적 창의력을 기르기 위해서는 일반적인(범교과적인) 창의적 프로그램에서 채택하고 있는 단순한 창의력 기법의 연습보다는 구체적인 과제를 해결해 나가는 실제적인 언어 활동을 통해서 하는 것이 바람직하다. 실제의 언어 활동에서 발현되는 창의력은 이해와 표현 모두 발상-구조화-언어화의 단계를 거쳐 결과가 나타난다. 창의력 프로그램은 발상, 구조화, 언어화, 메타화 등의 단계로 구성된다. 발상 단계에서는 느끼기와 깨닫기, 구조화 단계에서는 구체화하기, 관계짓기, 뒤집어보기, 미루어두기, 언어화 단계에서는 경험화하기, 감각화하기, 의미화하기, 개별화하기의 활동을 통해서, 메타화 단계에서는 선택하기, 배열하기, 평가하기 등의 활동을 통해서 학생들의 창의적인 능력을 신장시킬 수 있다. 본 연구의 활용 방안은 다음과 같다. 첫째, 언어적 창의력이 표현과 이해의 언어 활동과 별개로 존재하는 것이 아니므로 교과서의 학습 활동을 구체화하여 국어과 수업에서 창의적인 활동이 활발하게 이루어질 수 있도록 한다. 둘째, 발상 단계, 구조화 단계, 언어화 단계, 메타적 단계 등 각 단계에 적합한 활동들을 실제 수업에 활용할 수 있도록 구체화하고 나아가 학교장 재량활동 시간에 활용할 수 있도록 한다. The creativity which is essential ability in our own day is embodied by verbal creativity in Korean language education. The verbal creativity is realized in the all process of comprehension and expression. In this view it is more effective to develope verbal creativity through practical verbal activity than training creative technique. The creativity in the process of both comprehension and expression is similar. The creativity in the process of comprehension has to be embodied in text, it in the process of expression is based on new understanding about object. So that, the process of verbal creativity consists of the stage of idea that is starting point of new understanding, the stage of construction that organizes the new idea, the stage of language that embodies text. The program of verbal creativity consists of the stage of idea, construction. language and meta-cognition.

음부를 포함한 다발성 다유방증의 치험례

이신규,김잉곤,최회윤,류재만,조삼현 대한성형외과학회 1992 Archives of Plastic Surgery Vol.19 No.3

Accessory breast tissue is developed from persistence of breast tissue along the milk line which first beomes apparent at the 6th week of embryo and usually atrophies except for the thoracic area until the 9th week. It is much more common than amastia and occurs in approximately from 2 to 6 percent of the population. But multiple polymastia involving labia major is quite rare. We experienced one case of multiple polymastia involving labia majora & both axilla and 6 cases of polymastia & polyhelia, so we are willing to report our cases with a review of literature.

백혈병 세포주에 대한(±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 충남대학교 약학대학 의약품개발연구소 1991 藥學論文集 Vol.7 No.-

Using the colorimetric [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] (MTT) assay, we evaluated the chemosensitivity of 8 anticancer drugs{vincristine(VCR), vinblastine(VBL), adriamycin(ADR), cisplatin(CPDD), etoposide(VP-16), cytosine arabinoside(ara-C), bleomycin(Bleo) and cyclophosphamide(CYC)} and the cytotoxicity-enhancing effects of (±)-ar-turmerone and the extracts of the crude drugs {Lithospermum erythrorhizon(LE) and Scutellaria baicalensis (SB)} on the above mentioned anticancer drugs against HL-60 and KG-1 cells among 8 anticancer drugs, VCR, VBL, ADR, and CPDD inhibited the growth of both cell lines by more than 50%, while VP-16, ara-C, Bleo, and CYC were less effective. (±)-ar-Turmerone had significant inhibitory effects against both cell lines, showing the ID_50 values of 11.730 ㎍/㎖ and 0.292 ㎍/㎖ for HL-60 and KG-1 cells. respectively. But the extracts of LE and SB roots showed no significant cytotoxic effects. According to ID_50 values, the cytotoxicities of VCR, VBL and ADR against HL-60 were enhanced two, eight and three times by mixing (±)-ar-turmerone, five, seven and three times by adding the extract of LE root, and twenty, six and three times by mixing the extract of SB root, respectively. The cytotoxicities of the above mentioned drugs against KG-1 cell were enhanced two, seven and three times by mixing (±)-ar-turmerone, two, three and three times by combining with the extract of LB root, and two, five and two times by adding the extract of SB root, respectively. The cytotoxicity-potentiating effects of (±)-ar-turmerone and the extracts of LE and SB roots againg HL-60 cell were greater than KG-1 cell.

Luis Barragan의 후기건축에 나타난 지역주의 표현경향에 관한 연구

이용재,이정훈,김희규,문영삼 순천향대학교 교수학습개발센터 2005 순천향 산업기술연구소논문집 Vol.11 No.1

The purpose of this study is to define the architectural expression of regionalism in the late period of Luis Barragan, the representative architect of Modernism in Mexico. The view point of architectural expression, the essential quality of regionalism be related to the sensitivity, passionate, and purity. We select the works of L. Barragan in the late period : Barragan House(Tacubaya, 1947), Chapel for the Capuchinas(Tlalpan, 1952) and Gilardi House(Tacubaya, 1976). The result of this study shows that the architectural expression of regionalism on the his works in the late period are the passionate sensitivity, regional commonness and human being experience in Mexico.

백혈병 세포주에 대한(±)-ar-Turmerone, 자근 및 황금추출물에 의한 항암제의 세포독성 증강효과

이윤영,유관희,김삼용,안병준 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1991 No.-

치수 치근단 병소의 전구 위험요인으로서의 제 2 형 당뇨의 역할에 관한 소고

김진희,배광식,서덕규,홍성태,이윤,홍삼표,금기연 大韓齒科保存學會 2009 Restorative Dentistry & Endodontics Vol.34 No.3

Diabetes Mellitus (DM) is a syndrome accompanied with the abnormal secretion or function of insulin, a hormone that plays a vital role in controlling the blood glucose level (BGL). Type 1 and 2 DM are most common form and the prevalence of the latter is recently increasing. The aim of this article was to assess whet her Type 2 DM could act as a predisposing risk factor on the pulpo-periapical pathogenesis. Previous literature on the pathologic changes of blood vessels in DM was thoroughly reviewed. Furthermore, a histopathologic analysis of artificially-induced periapical specimens obtained from Type 2 diabetic and DM-resistant rats was compared. Histopathologic results demonstrate that the size of periapical bone destruction was larger and the degree of pulpal inflammation was more severe in diabetic rats, indicating that Type 2 DM itself can be a predisposing risk factor that makes the host more susceptible to pulpal infection. The possible reasons may be that in diabetic state the lumen of pulpal blood vessels are thickened by atheromatous deposits, and microcirculation is hindered. The function of polymorphonuclear leukocyte is also impaired and the migration of immune cells is blocked. leading to increased chance of pulpal infection. Also, lack of collateral circulation of pulpal blood vessels makes the pulp more susceptible to infection. These decrease the regeneration capacity of pulpal cells or tissues, delaying the healing process. Therefore, when restorative treatment is needed in Type 2 DM patients, dentists should minimize irritation to the pulpal tissue under control of BGL. 당뇨(Diabetes Mellitus)란 혈당을 조절하는 인슐린의 분비나 기능에 장애를 야기하는 질환으로 인슐린 의존성 여부에 따라 제 1 형과 제 2 형으로 분류된다. 본 종설은 최근 증가 추세에 있는 제 2 형 당뇨가 치수 치근단 병소의 병인 과정에 전구 위험 요인으로 작용할 수 있는지를 평가 하고자 문헌고찰을 통해 당뇨의 병인 과정에서 특징적으로 나타나는 혈관 합병증에 관해 알아보고, 부가적으로 제 2 형 당뇨 쥐 모델에서 인위적인 치수감염 후 얻은 치근단 조직의 조직병리학적 분석을 시행하였다. 조직학적 관찰 결과 제 2 형 당뇨 쥐에서 대조군에 비해 치수 치근단 병소의 크기가 증가하였고, 치수 염증 반응도 심하게 나타난 것으로 보아 당뇨 자체가 숙주를 감염에 취약한 상태로 만드는 전구 위험요소로 작용하였음을 알 수 있었다. 이러한 이유로는 첫째, 당뇨 시 전반적으로 나타나는 혈관 내 죽상 침착(atheromatous deposits)에 의해 혈관 내벽의 두께가 두꺼워져 미세 순환의 장애는 물론 탐식 세포의 기능 저하, 면역 세포의 혈류 이동이 차단되어 치수 감염 시 쉽게 치근단 병소로 이환될 가능성이 높고, 둘째 치수 혈관에서 특징인 측부 순환(collateral circulation)의 부재에 따른 살균성 다형핵 백혈구의 활동 억제를 포함한 미세 혈관계의 취약성으로 인해 치수 조직의 재생능이 저하되어 추가적인 감염원의 공격에 대한 방어 및 치유 저하를 더욱 심화시키기 때문인 것으로 사료된다. 따라서 제 2 형 당뇨 환자의 수복치료 시 치과의사는 당뇨 조절 하에서 치수 조직의 자극을 최소화하기 위한 세심한 처치가 필요하다.

자동차용 배터리의 방전 특성 연구

서삼희,이학우,김준범 울산대학교 1999 공학연구논문집 Vol.30 No.2

본 연구에서는 자동차에 탑재되는 배터리와 전기를 소모하는 부속장비와의 관계를 고찰하기 위하여 시뮬레이션 소프트웨어에 채용할 특정 배터리에 대한 수식적 모델을 제시하고자 자동차 배터리의 방전 특성에 대한 실험을 수행하였다. 배터리의 service history (최근의 충.방전과 정지 시간)는 용량에 영향을 미치므로, 본 연구에서는 일정한 온도와 방전율로 제한된 조건인 한국산업표준규격에 따라 자동차용 배터리에 적용되는 중부하실험 및 경부하실험과 보유용량실험을 수행하였다. 배터리 방전시 전압의 변화를 시간과 cycle에 대한 다항식으로 변환하여 시뮬레이션 소프트웨어의 입력변수로 활용하였다. The experiments were conducted to get discharge behavior of an automotive battery. Capacity of battery is affected by the service history, and the life test should be conducted under specific condition of temperature and discharge rate. Life test of heavy load, light load, and reserve capacity were performed under the guidance of Korean industrial standard battery test. The voltage variation of the battery during life test was transformed to polynomial equation to be used as an input variable of simulation software.

일부 자동차 공장 근로자들의 職業的 特性과 社會 心理的 Stress의 相關性 硏究

김성삼,홍지우,한현정,최희석,권소희,정해경,김삼태,송용선,이기남 한국전통의학연구소 2004 한국전통의학지 Vol.14 No.1

〈Objective〉 This study were carried out to study to assess the relationship between job characteristics, general characteristics, health behaviors, and psychosocial distress and suggested the preventive oriental medicine approaches in occupational health area. 〈Methods〉 We measured job characteristics(job demand, job control, jop insecurity) by The Karasek's Job Content Questionnaire, health behaviors(smoking, drinking, exercise, coffee), general characteristics at work by a self-administered questionnaire. Psycho social distress was measured by PWI(Psychosocial Well-being Index), a 18-item self- administered instrument. 370 data for research were collected through the process of oriental health examination with questionnaire in workplace. Statistical analysis was done by t test, oneway ANOVA, and hierarchical multiple regression analysis with SPSSWIN (version 10.0) 〈Results〉 Among the 152 respondents, the prevalence of high job strain was 27%(41 persons). The Odds ratio of high job strain was 3.11(95 2.12~4.11), and those of passive group and active group were 2.01(95 0.83~2.76) and 1.80(95 0.83~2.76), respectively. Our results supported the association between psychosocial distress and job strain. 〈Conclusion〉 The odds ratio of high strain isolated group(high strain group+low social support) was 3.59(95 2.05 5.13), but the odds ratio of high strain collective group was 1.32(95 0.23 2.41). Social support at work was modifing factor of the association between psycho social distress and job strain. Therefore we reviewed the evidence that economic depression was associated with psycho social distress in this study, and that the strength of the social support was important in maintain health.