치근단 미완성 치아의 자가치아이식

정지숙,박호원,이주현,서현우 大韓小兒齒科學會 2012 大韓小兒齒科學會誌 Vol.39 No.1

자가치아이식이란 자신의 치아를 구강 내의 한 위치에서 다른 발치와나 외과적으로 형성된 치조와로 이동시키는 술식이다. 통상적으로 이 술식은 상실되거나 보존하기 힘든 제1대구치를 다른 치아로 대체하거나, 매복된 견치를 악궁의 정상 위치로 이동시키거나, 전치부와 같이 심미적으로 중요한 부위의 상실된 치아를 소구치로 대체하는 경우에 많이 사용된다. 자가치아이식을 성공적으로 수행하기 위해서는 세심한 수술 기법과 더불어 적절한 증례 선택이 중요한데, 이식할 치아는 치근 발육이 1/2~3/4 정도 이루어진 미성숙 치아가 유리하고 근단공이 넓을수록 치수 재혈관화의 가능성도 높아져 이후의 근관 치료의 필요성도 줄일 수 있다. 본 증례들은 소아에서 치근단 미완성 치아의 자가치아이식을 통해 임상적, 방사선학적으로 양호한 치유 결과를 얻었고, 별도의 근관 치료 없이 양호한 치수 치유 결과를 보였기에 보고하는 바이다. Autogenous tooth transplantation can be defined as the surgical movement of a tooth from one position in the mouth to another in the same individual. The most common reasons for tooth transplantation include replacement of a missing first molar, transplantation of impacted canines to their normal positions in the arch, and transplantation of premolars in areas of missing teeth, especially in the anterior area of the mouth. The key to successful tooth transplantation is proper selection of graft with adequate root development as well as the design of surgical operation. Root development stage with half to three-quarter-developed roots increase the success rate of autotransplantation. We report the cases of successful autotransplantation which resulted in ideal healing of periodontal ligament, gingiva and alveolar bone. All transplanted teeth presented immature root formation at the moment of the procedure. After surgical procedure, we can observe good healing pattern without endodontic problem.

습식크리닝에 의한 지류문화재의 물성변화

천주현,장은지 국립중앙박물관 2005 박물관보존과학 Vol.6 No.-

지류문화재의 보존처리과정에서 실시되는 습식크리닝의 영향을 알아보기 위해 습식크리닝 전과 후의 물성변화를 관찰하였다. 조사방법으로 고지와 현대지 7종을 각각 습식크리닝 전과 후의 구조적, 광학적, 강도적 성질의 변화를 측정하였다. 그 결과 습식크리닝은 지류문화재의 물성변화를 일으키고 특히 안료, 먹, 염료 등의 구성성분을 약화시킬 수 있음을 확인할 수 있었다. To understand the influence of wet cleaning performed in the course of preserving paper items, the change of matter properties by before and after wet cleaning was observed. Specifically, structural and optical qualities and strength were measured. The result showed that wet cleaning caused a substance change in the paper items and particularly weakened the structure material of pigments, Chinese ink, dyes, etc.

프롤린 함량 증가 및 내건성 강화 관련 새로운 RING-Type E3 유비퀴틴 리가아제 애기장대 atrzf1 돌연변이체의 생리적 기능 연구

주현우,민지희,정문수,김철수 전남대학교 농업과학기술연구소 2021 농업생명과학연구동향 Vol.59 No.-

The covalent attachment of ubiquitin to proteins plays a fundamental role in the regulation of cellular function through biological events involving abiotic of biotic stress responses, immune responses, and apoptosis, Here, we characterize the biological function of the Arabidopsis thaliana RING Zinc Finger 1 (AtRZF1) in dehydration response. AtRZF1 was significantly reduced by drought stress. The atrzf1 mutant was less sensitive to osmotic stress than the wild-type during early seedling development, wheareas transgenic pants overexpressing AtRZF1 were hypersensitive, indicating that AtRZF1 megatively regulates drought-mediated control of early seedling developmeng. Moreover, the ectopic expression of the AtRZF1 gene was very significantly influential in drought sensitiv parameters including proline content, water loss, membrance ion leakage and the expression of dehy-dration stress-relat genes. ARZF1 is a functional E3 ubiquitin ligase, and its conserved C3H2C3-type RING domain is likely important for the biological function of AtRZF1 in drought response. Together, these results suggest that the E3 ligase AtRZF1 is an important regulator of water deficit stress during early seedling development.

전류응력이 고탄소강의 미세조직에 미치는 영향

지주현,이태근 서울産業大學校 2005 논문집 Vol.54 No.1

잔류응력은 재료에 부하되는 응력 패턴에 따라 구조물에 상이한 영향을 미친다. 특히 쇼트피닝 처리는 압축잔류응력에 많은 영향을 받고 있다. 이러한 잔류응력을 정확히 모니터링 할 수 있다면 실기 부품의 안전성 유지와 보수기간 및 잔존수명 예측에 유용하게 사용할 수 있다. 본 논문은 쇼트피닝에 의한 잔류응력과 미세조직 변화를 실험적으로 관찰하였다. 쇼트피닝 투사속도가 증가함에 따라 변형층의 두께가 증가하였다. 경도 및 압축잔류응력은 표면에서 깊이 방향으로 증가하였고, 내부에 형성된 압축 잔류응력의 깊이와 유사하게 감소하였다. 투사속도가 증가함에 따라 압축 잔류응력과 을력분포는 증가하게 되고, 입자 크기는 미세화 하였고 침상의 Bainite 조직이 발달 함에 따라 경도값도 증가하였다. Residual stress gives different impact on the microstructures according to the stress pattern loaded to materials, and it is useful for the prediction of safety maintenance, maintenance period and residual life of parts for practical training. This paper studied the changes of the residual stress and microstructure of SK-5M high carbon steel by applying shot peening. As shot ball speed of shot peening increases, the thickness of deformation layer has increased. Hardness and compressive residual stress increased vertically from surface. As compressive residual stress and its distribution increased, grain size became refined and Bainite structure of bed increased hardness.

복귀돌연변이시험을 이용한 이온화에너지 처리 우유 및 아이스크림의 유전독성학적 평가

유지숙, 한선경, 신명수, 구본철, 최지현, 이주운, 조철훈, 함준상, 이완규 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.1

본문참고

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

나사형 임플란트 고정체의 길이, 직경, 플랫폼 형태에 따른 임플란트와 주위조직의 응력분포

강지은,정현주,양홍서 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.1

Seven finite element models were constructed in mandible having single screw-type implant fixture connected to the second premolar-shaped superstructure, in order to evaluate how the length, diameter and platform shape of a screw-type fixture influence the stress in the supporting tissue around fixtures. The superstructure were made using UCLA abutment, and connected to the fixture with abutment screw. Each finite element model was varied in terms of length, diameter, and platform shape of the fixture according to the commercial fixture(3i Implant Innovations Inc, Palm Beach Gardens, FL33410, USA) while the superstructure and the mandible with a single fixture placed in it shared no difference in terms of appearance. In each model, 250N of vertical load was placed on the central pit of an occlusal plane and 250N of oblique load placed on the buccal cusp. The stress distribution in the supporting tissue and the other components was analysed using 2-dimensional Finite element analysis and the maximum stress in each reference area was compared. 1. Under lateral loading, the stress was larger in the larger in the abutment/fixture interface, and in the crestal bone, compared to the stress pattern under vertical loading. 2. The amount of stress at the superstructure was similar regardless of the length, diameter and platform shape of a fixture. 3. Around the longer fixture, the stress was decreased at the bone crest and subjacent cancellous bone and increased in the cancellous bone area apical to the fixture. 4. Around the wider fixture, the stress was decreased at the abutment/fixture interface, and the bone crest and increased in the cancellous bone area apical to the fixture. 5. Around the fixture having wider platform, less stress was resulted at the abutnent/fixture interface and the upper part of the cortical bone, compared to the fixture having standard platform. In short, the stress distribution of the supporting tissue was affected by length, diameter, and platform shape of a fixture, and the fixture which was larger in diameter and length could reduce the stress in the supporting tissues at the bone-fixture interface and bone crest area.

층상구조 산화물 Na_(x)Ni_(x/2)Ti_(1-x/2)O₂의 합성과 구조적 특성

신유주,곽지현 가톨릭대학교 자연과학연구소 1998 자연과학논문집 Vol.19 No.-

층상구조 산화물 Na_(x)Ni_(x/2)Ti_(l-x/2)0₂(0.60≤X≤1.0)이 고상합성법에 의해 Ar 분위기하에서 950℃-1100℃로 가열하여 합성되었다. 단일상 영역은 0.75≤x≤1.0에서 rhombohedral(O3), 0.60≤x≤0.75에서는 primitive hexagonal 상(P2)으로 결정되었고, x<0.60은 층상구조와 함께 pruderite 구조상이 공존하는 혼합상 영역이었다. 격자상수 a는 x가 감소함에 따라 단순감소 하였고 c는 반대로 증가하는 것이 관측되었는데 이는 Ni^(2+)와 Ti^(4+) 이온 반경의 차, (Ni/Ti)O₂ 층간의 정전기적 반발력, (Ni/Ti)O_(6) 정팔면체의 trigonal distortion 정도와 관련지어 논의되었다. O3에서 P2로의 구조전이 과정은 (Ni/Ti)-O와 Na-O간 경쟁적인 공유-이온 결합성의 변화에 기인하는 것으로 이해되었다. Na_(0.67)Ni_(0.33)Ti_(0.67)O₂의 경우 Rietvelt 분석법을 이용하여 그 결정구조를 결정하였다. Layer-type oxides Na_(x)Ni_(x/2)Ti_(l-x/2)0₂(0.60≤x≤1) have been prepared for the first time by solid-state reaction by heating the appropriate mixtures of starting materials at 950℃-1100℃ under Ar ambience. Two consecutive single phases were observed, rhombohedral(03) phase for 0.75≤x≤1.0 and hexagonal one(p2) for 0.60≤x<0.75, and a mixed-phase appeared including pruderite phase with x<0.60. Lattice parameter a decrease with x, while c increases as x diminishes. Such behaviors have been discussed on the basis of the difference of ionie radii between Ni^(2+) and Ti^(4+), the electrostatic repulsion of (Ni/Ti)0₂ slabs and the evolution of trigonal distortion of (Ni/Ti)0_(6) octahedra. Structural transition from 03 to P2 has been understood due to the competitive iono-covalency between (Ni/Ti)-0 and Na-0 bonds. As for Na_(0.67)Ni_(0.33)Ti_(0.67)O, the crystal structure has been determined by the Rietveld profile-analysis method.

맹출 지연 영구치의 자발적 맹출 유도 : 증례보고

권지훈,박호원,이주현,서현우 大韓小兒齒科學會 2007 大韓小兒齒科學會誌 Vol.34 No.4

Delayed tooth eruption is the most commonly encountered deviation from normal eruption time. Racial, ethnic, sexual, and individual factors can influence eruption and are usually considered in determining the standards of normal eruption. Delayed tooth eruption was affect to the dentition and facial growth, so that when it occurred careful evaluation should be performed to establish the cause and the treatment plan accordingly. Present 3 cases of delayed tooth eruption by periapical lesion. underdevelopment of incisior and compound odontoma were successfully treated. In these cases, we could observe spontaneous eruption of the delayed erupting tooth after removal of interrupting factor and space regaining with maintaining. 정상적인 맹출 시기는 종족,인종,성별과 개인적인 요소에 의해 결정되며,만약 정상적인 맹출 시기에서 두드러지게 벗어날 경우 맹출 지연이라고 한다. 영구치의 맹출 지연 원인은 다양하며,발생 시 치열 및 악궁에 부정적인 영향을 줄 수 있어 조기진단 및 치료가 중요하다. 본 증례들에서는 치아종 및 치아발육부전 그리고 낭종으로 인한 맹출지연을 보이는 각각의 환자에 대해 맹출 방해 인자의 제거와 맹출 공간의 형성 및 유지만으로 자발적 맹출을 이룰 수 있었기에 보고하는 바이다.

층상구조 산화물 Na_(x)Co_(x/2)Ti_(1-x/2)O₂(0.66≤x≤1)의 합성 및 결정화학 연구

신유주,곽지현 가톨릭대학교 자연과학연구소 1997 자연과학논문집 Vol.18 No.-

층상구조 산화물 Na_(x)Co_(x/2)Ti_(1-x/2)O₂(0.66≤x≤1)이 고상합성법에 의해 Ar 분위기, 950℃에서 합성되었다. 단일상 영역은 0.75≤x≤1에서 rhombohedral, x=0.66에서는 primitive hexagnonal 상으로 결정되었고, 0.66<x<0.75에서는 두 개의 상이 공존하는 상 경계가 존재하였다. 두 구조의 결정 화학적 논의가 조성과 연관되어 공유-이온 결합성을 중심으로 이루어졌다. 또한 온도에 따른 자화율 거동을 분석한 결과, 두 구조 내에서 Co^(2+) 이온은 high-spin(S=3/2; ⁴T) 상태임을 알 수 있었고, 자기적 상호 작용에 대해서도 논의되었다. Layer-type oxides Na_(x)Co_(x/2)Ti_(1-x/2)O₂(0.66≤x≤1) have been prepared for the first time by solid-state reaction by heating the appropriate mixtures of starting materials at 950℃ under Ar ambience. They exhibit two kinds of structure according to x, respectively rhombohedral one for 0.75≤x≤1, and primitive hexagonal for x=0.66. Discussion of crystal chemistry of both structure has been made mainly focused to the iono-covalency of Na-O, and correlated to the chemical composition. Magnetic susceptibility measurements confirmed the high-spin state(S=3/2; ⁴T) of Co^(2+) ions in both structures and their magnetic interactions has been also discussed.