전주시 도시경관의 변화과정에 관한 연구

서주환,김홍균,승지현,김옥경,최선주,박선영 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

The object of this research is about how jeon-ju, which is one of the historical cities is changed according to the flow of generation. In this analysis, product and enemy factors will be studied. The inner and urban landscape of the generations of the 1860s, 1930s and modern times will be surveyed and compared in the context to grasp those factors. Analysis will be applied to this modern historical city by theorizing how these factors will effect future development. Today's modern landscape will be compared and analyzed based on the effects and abstractions of the recent landscape immediately preceeding current times. Modern conditions will again be placed in context, by suggesting future potential developments. In the result, first, considering present conditions of the landscape which set the stage for the Japanese invasion, an evaluation will be made on the best course of action for future development of street landscape. Second, the question of preserving the history and culture of this rich and ancient city through network of modern street landscape naturally will be posed. Finally, an analysis of the difference between the old and modern landscape will be evaluated, in preparation for suggestions of future development.

복합문화공간의 색채계획 : 수원시 영통구 상업지구를 중심으로

서주환,여화선,최선주,박선영,김옥경,승지현,김홍균 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

The recognition on leisure living which have been enjoyed by prestige level from popular persons is now widely spreaded in modern capitalism society and change of the leisure living influenced very much to the society and Industry. The 5 day work per week system expanded to the school and contemporary leisure living of the people is recognised as one culture with various contents. This change of leisure living made a recognition on the need for a space for leisure culture contents, which related to a creation of Complex-culture facility to contain various type of multiple leisure culture. The Complex-culture facility is mainly focused on the entertainment space with increased leisure living, which is consist of important element of the Complex-culture facility as performance space, exhibition, sports and shopping space to construct performance hall, theater, exhibition room, sports center, shopping mall, leisure space and plaza. This study, therefore, will Investigate on the function and value of color, and review on the cases of Complex-cultural facility and then choose a space of cultural element lack. It will recompose in Complex-cultural facility.

수목장(樹木葬)의 특성에 관한 고찰

서주환,최현상,정해천,승지현 경희대학교 디자인연구원 2005 예술· 디자인학연구 Vol.8 No.2

To secure a space for graveyard in a funeral has become one of the new issues in Korea. This caused the problems of graveyard shortage, destruction of national landscape, inroad of territory, and ecological environment. However, In eco-friendly method of funeral, the Woody Plant Funeral is a new form of Funeral to bury the ashes of the deceased under the wood so it participate with eternal life in wood and forest by provision of nature(wood and people return to nature to be born in nature). The purpose of this paper is to explain one of the counterplan which the Woody Plant Funeral solve graveyards problem.

갑상선 종양에서 thrombin receptor (PAR-1)의 발현 양상

박지영,목지오,김여주,박형규,김철희,변동원,서교일,유명희,조현득,오미혜,김상진 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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의정부시의 도시경관 기초자료 도출을 위한 주민의식 조사

서주환,최현상,승지현,박대우 경희대학교 디자인연구원 2004 예술· 디자인학연구 Vol.7 No.1

As various values become respected with changing paradigm. Our modern cities are characterized by indetermination ever. Change of life style make people concerned more about city environment. Our contemporary society has gradually respected and sportlighted the importance of human being as principal, and conventional awareness about urban environment has been changing owing to higher interest in 'a life quality in the city' than ever, We have beer preferred an urban environment planning to make city more sustainable and agreeable scape. But nowaday, resident's demands actively reflect on city planning them ever to make satisfaction in city life. This study aims to investigate positive landscape factors and create urban image-map in order to find out instinctive data use on urban environment planning. It can be introduce sustainable and agreeable city scape in Uijung-Bu.

어유와 pectin의 혈장 cholesterol 저하 효과에 관한 비교연구

박현서,이지숙 慶熙大學校 1997 論文集 Vol.26 No.-

The present study was designed to compare the mechanism of plasma cholesterol lowering effect of fish oil and pectin by measuring the levels of plasma lipids, hepatic cholesterol and HMG CoA reductase activity and fecal excretion of total bile acids and neutral sterol in rats. Male Sprague Dawley fats (7 weeks-old) were divided into three groups according to their fat sources, beef tallow(BT), corn oil(CO), and fish oil(FO) and then each group subdivided into three groups again depending on fiber(cellulose or pectin and fiber-free as control). Rats were fed the experimental diet containing dietary fat at 15%(w/w) and fiber at 6%(w/w) level for 20 weeks. Fish oil significantly reduced the levels of plasma total cholesterol, VLDL-Chol, LDL-Chol and HDL-Chol. Fish oil inhibited hepatic HMG CoA reductase activity compared to those of other dietary fat(p<0.05). Compared to cellulose, pectin significantly reduced the levels of plasma total cholesterol, VLDL-Chol and LDL-Chol but increased HDL -Chol level in all dietary fat groups. Pectin significantly increased the excretion of total neutral sterol in feces and lowered hepatic content of cholesterol. Pectin also significantly increased hepatic HMG CoA reductase activity. Overall, pectin could reduce plasma lipid level by interfering absorption of biliary cholesterol and bile acid, which resulting in the higher excretion of neutral sterol and bile acid in feces and increased hepatic cholesterol synthesis. However, fish oil reduced plasma lipid level by inhibiting HMG CoA reductase activity. Therfore, it is recommended to consume more fish and its product and vegetable source of dietary oil rich in ω-3 fatty acid and also more fruit and vegetable and grain product rich in fiber to reduce the risk factor against cardiovascular disease.

인공지반의 조경적 활용에 관한 국내 연구동향 : 옥상녹화를 중심으로

김동찬,서주환,김옥경,승지현,김홍균,최선주,박선영 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

This study aims at understanding the trend of researches carried out on the subject of rooftop afforestation. The issue of rooftop afforestation is receiving attention as one of the plans to secure green zones in urban area. While the actual execution of rooftop afforestation in Korea in only in the initial state, thus in not activated, studies on this subject have been actively carried out particularly in terms of the methods of rooftop afforestation. Recently, studies are being actively performed on the creation and effect of rooftop afforestation. However, these studies tend to focus on specific areas. This leads to the necessity to approach the issue of rooftop afforestation with a wider perspective. Therefore, in the study, the previous studies on rooftop afforestation carried out both in and outside the country are categorized as the study on the methods, effect and activation plans of rooftop afforestation, thus are examined to understand the recent trend in the study of rooftop afforestation. The results indicate that domestic studies. which was centered on the methods to promote rooftop afforestation. have been expanding into the study on the methods to establish eco-habit at on rooftop as well as on the environmental and economic effect rooftop afforestation.

방한 일본인 관광객의 패션상품 구매행동에 관한 연구

류덕환,조지현,서철현 啓明大學校 生活科學硏究所 2002 科學論集 Vol.- No.-

The purpose of this study was to investigate demographic profiles, purchase motivation, and purchase behavior of consumers of inbound tourists. More specially, the samples chosen for the study were Japanese inbound tourists from Dongdaemoon fashion market by means of questionnaire method. The reason why Japanese are the highest proportion in inbound tourists. Of 250 Japanese tourists who had buying experienced answered data, 210 data were usable. The results were as follows. The primary motivation of purchasing fashion goods was concerned with the price. They had chance to buy various items, especially they bought lots of T-shifts in the number of purchase items. In addition, Japanese tourists preferred more natural textiles. With regard to the important consideration when they purchase fashion goods, design, price size, usefulness, and color were more important. Most Japanese tourists were officers and students, and higher educated in demographic variables. Their age were in twenties, thirties, and women tourists were a little more than men.

항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

아시아 지역 폐렴 구균의 항균제 내성 현황 및 변화 양상 : Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study

정숙인,김나영,손준성,기현균,고관수,서지연,장현하,김연숙,오원섭,백경란,이남용,송재훈,항생제 내성 감시를 위한 아시아 연합 (ANSORP) 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : 1980년대부터 페니실린을 비롯한 β-lactam 계열과 비 β-lactam 계열 항균제에 대한 폐렴구균의 항생제 내성이 급격하게 증가하여 국내 뿐 아니라 세계적인 문제로 대두되고 있다. ANSORP 에서는 아시아 지역에서 폐렴구균의 항균제 내성과 그 변화 추이, 내성의 기전 및 위험인자를 분석하고자 본 국제 공동 연구를 시행하였다. 재료 및 방법 : 1999년 11월부터 2001년 8월까지 아시아 지역 12개국의 14개 기관에서 폐렴구균 감염증 환자의 임상 검체로 분리된 침습성 폐렴구균을 대상으로 액체배지 미량희석법을 이용하여 16개 항생제의 MIC를 구하였다. 위험인자의 분석을 위하여 폐렴구균 감염증 환자를 대상으로 의무기록지를 조사하였다. Quellung 반응을 통해 혈청형을 결정하였다. 결과 : 총 685균주 중 52.4%가 페니실린에 대하여 비감수성(중등도 내성 22.9%, 내성 29.5%)을 보였고, 그 빈도는 베트남(92.1%), 스리랑카(85.7%), 홍콩(67.9%), 한국(64.5%)의 순이었다. Erythromycin에 대한 비감수성 비율은 베트남(92.1%), 대만(87.7%), 한국(80.6%), 홍콩(76.8%) 등에서 높게 나타났고, 베트남, 대만, 한국, 홍콩 등의 erythromycin의 MIC_(90)이 32㎍/mL를 넘는 고도내성을 보였다. 홍콩, 싱가포르, 대만, 인도에서는 fluoroquinolone에 대한 내성 균주가 출현하였다. 전체 균주 중 다제내성 균주의 비율은 47.7%였다. 혈청형은 19형과 23형이 가장 많았고, 그 외 6형, 14형 등이 있었다. 페니실린 비감수성 감염증의 위험인자로는 5세 미만(OR=1.7; 95%, CI, 1.2-2.4; P=0.002), 기관지폐질환(OR=2.0; 95%, CI, 1.3-3.1; P=0.003), 악성종양(OR=2.3; 95%, CI, 1.2-4.6; P=0.015), 스테로이드의 사용(OR=2.8; 95%, CI, 1.1-7.4; P=0.032)이 확인되었다. 결론 : 침습성 폐렴구균 균주를 대상으로 한 본 연구의 결과 아시아 국가들에서 페니실린, β-lactam 및 macrolide에 대한 폐렴구균의 내성률 및 내성 정도가 급증하고 있음을 확인하였다. Background : Emergence of pneumococcal resistance became a global issue since 1990s. According to the ANSORP studies with clinical isolates and carriage isolates between 1996 and 1999, some Asian countries showed alarmingly high prevalence of resistance to penicillin and other antimicrobial agents. To investigate the changing trends of pneumococcal resistance, ANSORP study group has performed a multinational surveillance study with invasive pneumococcal isolates from Asian countries. Methods : All isolates from various invasive pneumococcal diseases were prospectively collected from 14 centers in 12 countries between November 1999 to August 2001. Broth microdilution tests with 16 antimicrobial agents were performed according to the NCCLS procedures. Serotyping was performed by means of Quelling reaction with use of group-specific antisera. Results : A total of 685 isolates were collected. Overall, 52.4% of invasive isolates from Asian countries were not susceptible to penicillin (intermediate (1), 22.9%, Resistant (R), 29.5%). Vietnam showed the highest prevalence of penicillin non-susceptibility (1 20.6%, R 71.4%) followed by Sri Lanka (1 71.4%, R 14.3%), Hong Kong (1 24.1%, R 76%) and Korea (1 9.7%, R 54.8%). China (I 19.8%, R 23.4%) and Malaysia (1 9.1%, R 29.5%) also showed remarkable increase in penicillin resistance compared with previous ANSORP data, which were less than 10%. Vietnam (92.1%), Taiwan (87.7%), Korea (80.6%), and Hong Kong (76.8%) showed high prevalence of erythromycin resistance. MIG_(90)S for ciprofloxacin were 4 ㎍/mL (Hong Kong) and 2 ㎍/mL (11 Asian countries except Hong Kong), respectively. Conclusion : Compared with previous data from ANSORP studies, antimicrobial resistance among invasive pneumococcal isolates has markedly increased in Vietnam, Sri Lanka, Taiwan, China, and Malaysia. Continuous surveillance of pneumococcal resistance in Asia is strongly warranted.