지중내 공동 탐지를 위한 비파괴 검사 기법에 대한 실험적 연구

유정동(Jund Dong?Yoo),양학모(Hak Mo?Yang),장기창(Ki Chang?Jang),강승민(Seung Min?Kang),조소현(So Hyun?Cho),김현기(Hyun-Ki?Kim),Seung Soo?Kim,Da Bin?Jin 대한토목학회 2018 대한토목학회 학술대회 Vol.2018 No.10

임상증례중심 성인 전문적 심장구조술 교육과정에 대한 고찰

유은영,박승현,박규남,최세민,김세경 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: To describe the first experience of case-based advanced cardiac life support(ACLS) course in Korea. Methods: We have given case-based ACLS course to 13 nurses(6 emergency nurses, 4 coronary care unit nurses, 3 professors) and 17 physicians(4 emergency physicians, 12 emergency residents, 1 intern). We performed the case-based ACLS course according to 1992 American Heart Association guidelines and recommendations for advanced cardiac life support by american ACLS instructors(1 pulmonologist, 4 critical care nurses). We performed final theoretical written test and 2 times written survey (immediate and 100th day after the course) about the course. Results: On final written test, all practitioners answered at least 70% of the questions correctly. There was no significant difference between nurses and physicians(86.2±3.6 of physicians and 82.5±6.8 of nurses, p=0.06). 90% of participants considered that case-based advanced cardiac life support was acceptable. 100th day after the course, 93% of participants answered that ACLS course have been helpful on his/her job and also want retraining of ACLS course. 70% of participants considered that ideal ACLS training committee in Korea is the Korean Society of Emergency Medicine. Conclusion: Case-based ACLS course is a useful educational method for physicians and nurses in Korea. In the future, we should organize Korean resuscitation committee and then make guidelines for ACLS, and then continuously educate physicians and nurses.

청각장애학생과 일반학생의 심폐기능 비교 연구

유승희,최현희 경희대학교 체육과학연구소 1997 體育學論文集 Vol.25 No.-

The purpose of this, study was to investigate and compare pulmonary ventilation, cardiorespiratory fuction of deaf person and normal person. For this purpose, 26 subjects(13 deaf person, 13 normal person) were selected. The results were as followings. 1.Pulmonary ventilation 1)The slow vitae capacity showed great significant difference(p<.05) and the predominant order of the mean value of slow vital capacity was deaf person(4.13±0.70 l). normal person(4.71 ±0.38 l). 2)The forced vital capacity showed great significant difference(p<.001) and the predominant order of the mean value of forced vital capacity was deaf person(3.84±0.67 l), normal person(4.54±0.47 1). 3)The forced expiratory volume in 1 second showed great significant difference(P<.001) and the predominant order of the mean value of forced expiratory volume in 1 second was deaf person(3.56±0.34 l). normal person(4.10±0.41 l). 4)The forced expiratory flow 200-1200ml showed great significant difference(P<.001) and the predominant order of the mean value of forced expiratory flow 200-1200ml was deaf person(7.35 ± 1.321), normal person(9.20± 1.25 l). 5)The maximal voluntary ventilation showed great significant difference(p<.05) and talc predominant order of the mean value of maximal voluntary ventilation was deaf person(119.85 ±24.98 l), normal person(152.43 ±30.39 l). 6)The precent forced expiratory volume in 1 second, forced expiratory flow 25-75%. peak expiratory flow, slow vital capacity showed no significance. 2.Cardiorespiratory function 1)The ventilation in time of maximum exercise showed great significant difference(P<.05) and the predominant order of the mean value of the ventilation in time of maximum exercise was the deaf person(103.88±18.45 l/min), normal person(122.51 ±20.18 l/min). 2)The heart rate in time of maximum exercise showed significant difference(P<.05) and the predominant order of the mean value of the heart rate in time of maximum exercise was deaf person(198.38±5.47beats/min), normal person(203.42±6.66beats/min). 3)The ventilation in time of rest, heart rate in time of maximum exercise, oxygen pulse in tilde of maximum exercise and rest, oxygen consumption in time of maximum exercise and rest, carbon dioxide production in title of maximum exercise and rest, oxygen consumption per kg body weight in time of maximum exercise and rest, tidal volume in time of maximum exercise and rest, respiratory rate in time of maximum exercise and rest. showed no significance.

국산 EXTENSOMETER의 개발에 관한 기초 연구

유현승,김갑용,김두만 한국 항공대학교 항공산업기술연구소 1999 航空宇宙産業技術硏究所 硏究誌 Vol.9 No.-

본 연구는 구조물의 측정에 이용되는 Extensometer를 국산화하는 것을 목적으로하였다. 외국의 시방서를 참고로 스트레인게이지를 이용하여 시제품을 제작하였다. 수감체는 알루미늄 합금을 사용하여 최대용량을 4 Kgf로 하였다. 시제품을 제작하고 정적인 Calibration 을 한 후 성능 평가를 하였다. 성능 평가는 알루미늄 시편에 시제품을 고정시키고 MTS로 반복하중을 가하는 방법으로 하였다. 시제품의 성능은 단일축 게이지보다 4배의 출력을 보였다. 또 최대하중의 5%의 하중을 8시간(약10000회)동안 반복적으로 가하였다. 이때 실험전과 실험후의 출력이 일정한 값을 보였다. 앞으로 실제 구조물을 측정할 수 있는 용량의 Extensometer를 제작하기 위하여 Extensometer의 재료와 열처리 기술에 대한 연구가 필요하겠다. 또 실제구조물을 측정하고 그 실용성을 평가해 보겠다. In this paper, the technique to make our own's extensometer is studied. The extensometer is to measure a structure. The prototype is manufactured by using a strain-gauge with the help of a foreign manual. The capacity of sensing part in aluminum alloy is 4 Kgf. The prototype is estimated after static calibration is done. The MTS is used to estimate the protype. The ability of a prototype is 4 times than it of an uniaxial strain-gauge. The 5 percent of maximum force is loaded repeatedly for 8 hours. The result shows that experiment is equal to theory. Later, the material of an extensometer and the technique of heat treatment must be studied to measure a real structure.

엘리트 알파인 스키 선수와 대학서클 알파인 선수의 등속성 근력 발현 특성에 대한 비교 연구

유승희,안정현,최현희 경희대학교 체육과학연구소 2001 體育學論文集 Vol.29 No.-

The purpose of this study was to compare isokinetic muscle strength between elite players and college players on alpine skiing and to offer foundamental information on characteristics of thigh muscle strength for elite players and effective training method for college club players The subjects of this study were 10 national ski players and 10 college club players. Also, the experimental instruments used were Martin's anthropometer(PKS-100, Japan), weight meter(TBF-202, Japan), and isokinetic equipment(CYBEX NORM, USA). To analyze the data, the statistical method used in this study were mean, standard deviation, and t-test using SPSS for Windows(Version 10.0.7). Based on aforementioned research method, the results of this study are as follows. 1. In peak torque, elite group was higher than college club group. Especially, right extension(p〈.05) and right flexion(p〈.01) were significant high in 240˚/sec. 2. In peak torque % of body weight, elite group was significant high on riggtㆍleft extension and flexion in 60˚/sec & 240˚/sec. 3. In angle of peak torque, elite group was higher than college club group. Especially, left extension(p〈.01) was significant high in 60˚/sec. 4. In average power, elite group was higher than college club group. Especially, right extension(p〈.05) and right flexion(p〈.01) were significant high in 240˚/sec. 5. In total work, elite group was significant high on rightㆍleft extension and flexion. However, on the muscle endurance ratio, there was no significant difference. 6. In peak torque for flexion/extension, there was no significant difference between elite group and college club group.

치수/치근단 질환에 이환된 영구치의 치수 조직 재생과 치근 형성

유연지,백승호,손호현 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.4

최근 치수 질환 또는 치근단 질환을 가진 미성숙 영구치에 대한 보존적 치료의 방법으로 여러가지 근관 내 소독 약제를 이용하에 증상 개선은 물론 치근의 성장 및 치수의 재생이 이루어진 증례들이 보고되고 있다. 그 기전에 대해서는 아직 명확하게 밝혀지지는 않았지만 여러가지 줄기 세포 또는 미분화 간엽 세포들이 관여하는 것으로 생각되며, 실제로 재생된 조직에서는 대부분백악질양또는골양물질의 침착이 관찰되고 있다. 이 새롭고보존적인 치료접근 방법은 다능성 줄기 세포와 다양한조직 공학 기술에 대한 연구와 더불어, 재생적 근관 치료에 더 밝은 비전을 제시하고 있다. Numerous cases about additional growth of roots or pulp tissue regeneration by using various intracanal medicaments in immature permanent teeth with periapical or pulpal disease have been reported. The underlying mechanism has not been clearly delineated. but it has been widely accepted that undifferentiated mesenchymal cells and stem cells are involved. Moreover, the growth and deposition of osteoid or cementoid tissues have been observed in regenerated pulp and roots. This new and non-invasive treatment has brightened the future of endodontics. and enlarged the vision of regenerative root canal treatment with multi-potent stem cells and various tissue engineering techniques.

Jahn의 Turnen이 現代 器械體操에 미친 影響

정삼현,배정하,서승유,김규환,이동갑,하정호 東亞大學校 附設 스포츠科學硏究所 1997 스포츠科學硏究論文集 Vol.15 No.-

Among the school gymnastics facilities, perhaps the most common ones are gymnastics apparatus. That's why a historic study in the event of havy gymnastics is required. The researchers here have examined the origin of gymnastics with apparatus centered on Jahn's "turen" exercise. The results are as follows : 1. Heavy gymnastics originally contained a lot of elements from field and track events. It had aims of obtaining natural physical movement and enhancing work efficiency. 2. An outdoor event turnen was banned and changed into an inddor event. The fact that apparatus gymnastics is nowadays held indoors reveals the decisive influnece of Jahn's turnen exercise. 3. Jahn's balance beam exercise was at first played for the purpose of blancing oneself and merely for fun. It has developed into the present from through wide distribution and elaboration. 4. Jahn first used the term of parallel bars and the present women's event of parallel bars resembles Jahn's. 5. Jahn's horizontal bars have also had a great effect on today's event of horizontal bars.

제2형 당뇨병 동물모델인 OLETF 쥐에서 장기간 라미프릴 투여가 내당능 및 췌도 베타세포에 미치는 효과

고승현,윤건호,김명미,안유배,송기호,유순집,손현식,차봉연,이광우,손호영,강성구 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.6

연구배경:최근 소개된 HOPE(Heart Outcomes Prevention Evaluation)study의 결과에 의하면, 심혈관질환이나 이에 대한 위험인자가 1가지 이상인 9,541명을 대상으로 안지오텐신 전환효소 억제제의 일종인 라미프릴을 투여하여 사망율과 뇌졸증, 심부전, 당뇨병 합병증이 개선되었을 뿐 아니라 다른 항고혈압제에 비해 새롭게 당뇨병으로 진단되는 환자가 줄었음을 보고한바 있다. 이에 저자들은 라미프릴(ramipril)을 제2형 당뇨병 동물모델에 장기간 투여함으로써 당뇨병을 예방하거나 고혈당 상태 또는 인슐린 감수성을 개선시킬수 있는지를 알아보고자 하였다. 방법:생후 24주된 체중 400∼450g의 OLETF와 LETO 쥐를 대상으로 6개월간 라미프릴 경구투여 하였고 혈압, 24시간 단백뇨 및 인슐린 내성검사를 시행하였다. 6개월 이후로는 8주간 투여군과 대조군의 체중을 비슷하게 맞추어 내당능 상태를 평가하였고 이후 다시 8주간 고농도 포도당을 투여하였다. 경구당부하검사를 시행한 후 희생시켜 조직표본을 만들어 guinea pig anti­human insulin 항체로 염색후 DAB로 발색하여 point count 법으로 베타세포를 정량하였고, 면역염색으로 췌도의 변화와 섬유화의 정도를 관찰하였다. 결과:라미프릴을 6개월간 투여하였을 때 OLETF 쥐에서 1)체중 증가가 적었으며 2)경구 당부하검사시 포도당하 면적은 의미있게 감소하였고 3)인슐린 내성검사상 Kitt가 증가되는 경향을 보였으며 4)수축기, 이완기 혈압과 24시간 단백뇨양이 의미있게 감소하였고 5)체중을 맞추면 내당능 상태가 비슷해졌다가 고농도 포도당 주입시 다시 포도당하 면적이 대조군에서 더 증가되었다. 라미프릴 투여군에서 췌도변형 및 파괴와 탈과립, 췌도내 섬유화가 감소하였다. 결론:본 실험에서는 인슐린 비의존성 당뇨병 동물 모델인 OLETF 쥐에서 당뇨병 발생 이전 단계부터 장기간 라미프릴을 투여할 경우 체중증가가 적었고, 투여군과 대조군의 체중을 맞추었을 때는 내당능상태의 차이가 없아가 고혈당 투여시 다시 투여군과 대조군에서 의미있는 차이를 보였다. 라미프릴 투여가 베타세포의 기능면에서 이로운 효과를 보일 것으로 생각되었다. 따라서 비만한 환자에서 안지오텐신 전환효소 억제제의 장기투여는 단백뇨 감소, 혈압강하 효과 이외에 체중증가의 억제 및 당뇨병 발생을 억제할 가능성을 시사한다. Background : In a Heart Outcomes Prevention Evaluation HOPE study, ramipril, a long-acting angiotensin-converting enzyme (ACE) inhibitor, significantly reduced the death rates the number of myocardial infarctions, strokes, heart failure as well as the risk of complications related to diabetes and of diabetes itself. However, it is known that ACE inhibitors improve glucose tolerance or insulin sensitivity or reduce the incidence of diabetes. Methods : 24 week-old OLETF (Otsuka Long Evans Tokushima Fatty) rats weighing 400 ~ 450 g were used in this study. 4 groups of rats were examined in parallel for 40 weeks. The OLETF rats were randomized for treatment with an aqueous solution of ramipril (5 mg/Kg) daily [OL (RMP), n=10)] and with saline [OL (CON), n=10)]. The LETO rats were also randomized in the same was as the OLETF rats (LT(RMP), n=10, LT (CON), n=10). The blood glucose level, body weight, systolic and diastolic blood pressure was assessed every month. At 3 and 6 months, the 24hrs urinary protein concentration was measured, and as insulin tolerance test and oral glucose tolerance test were conducted in all experimental groups. After 6 months, the body·weight was matched for 2 months in each corresponding group. Subsequently, a 15% sucrose loading was done for 2 months. After the glucose tolerance test, the pancreas was excised and immuno histochemical staining was conducted for insulin to quantify the beta cell mass by a point-counting method. In addition, the islet morphology was evaluated in the pancreas. Results : Ramipril treatment for a period of 6 months improved the 2hr blood glucose level, the area under the glucose curve in the oral glucose tolerance test, insulin sensitivity in addition to lowering significantly systolic and diastolic blood pressure and 24hrs urinary protein level significantly in OLETF rats. Of note, a lower weight gain was observed in both the ramipril-treated animals at 6 months. After weight matching, the AUC g and 2hr blood glucose level values were similar between the corresponding groups, but a 15% sucrose loading worsened the AUC g value. Histologically, the islets were less disorganized and the extent of fibrosis was lower in the ramipril-treated OLETF rats in the trichrome stain. Conclusion : Long-term treatment of ramipril, a long acting angiotensin-converting enzyme inhibitor may be useful for suppressing weight gain and proteinuria in addition to having a protective effect on the islet to harmful stimuli such as hyperglycemia (J Kor Diabetes Asso 25:469~482, 2001).

자동 경계 탐지(Automated Border Detection)심초음파도를 이용한 좌심방 면적 및 기능의 평가

김현주,주승재,임진형,정효균,이영수,유호대,차태준,이재우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

부착성 동물세포의 Scale-up을 위한 방법의 개발

김승모,송상호,최명락,유은정,임현수 여수대학교 1997 論文集 Vol.11 No.2

This study was a protocol of serial propagation for anchorage-dependent animal cell. Vero. by the optimization of trypsin and EDTA concentration in T-25 flask. Commen enzymetic treatment in PBS solution has been modified for a high degree of cell datachment from T-25 flask and for transfer of a maximum number of viable cells from one culture to the next during the scale up process. Culture of Vero cells were washed with Dulbecco's modified Eagle's medium(DMEM) and then exposed to DMEM containing trypsin(0.025%) and EDTA(0.16%). Up to 90% of cells detached from bottom of flask and the viability of cells was greater than 93%. The protocol using the developed method was successfully applied to the next 10 times scale up process. Consequently, the developed method changed multiple steps of processes to one step, so it promised th easy scale-up and low cost demand of animal cell culture.