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구조적 불연속에 기인하는 원통구조물의 응력집중현상에 관한 유한요소법에 의한 연구
김두만,정세헌 한국산업안전학회 1988 한국안전학회지 Vol.3 No.2
The stress concentration phenomena due to the structural incontinuty are studied by finite element method. In this study, a circular cylinder is treated. Under the axial load, the membrance action is dominate and the 24 D.O.F. cylindrical membrane finite element is used. The assembly of this element can successfully represent the original structure geometrically. The internal displacement function is such organized that the inter element compatibility condition is fully satisfied. In this study, the stress concentration factors due to the presence of a hole on the cylinder wall are obtained, and the factors versus the location of the hole is computed and plotted. It is found that the hole effect on the stress concentration disappears beyond the neighboring region of the hole size from the edge of the hole. Those results are useful for practical design in determining the region where the re-inforcing is necessary.
김두만 대한의사협회 2017 대한의사협회지 Vol.60 No.12
Diabetes mellitus is characterized by hyperglycemia due to insulin deficiency and/or insulin resistance. Cardiovascular disease (CVD) is a major comorbidity of type 2 diabetes mellitus, and is the most common cause of death in people with diabetes mellitus. Several clinical trials have addressed the long-term effects of near-normoglycemia on CVD, but did not find evidence of an effect. However, some recent clinical trials of sodium glucose cotransporter 2 inhibitors (EMPA-REG [Empagliflozin Cardiovascular Outcomes and Mortality in Type 2 Diabetes Trial], CANVAS [Canagliflozin Cardiovascular Assessment Study]) or glucagon-like peptide-1 agonists (LEADER [Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation], SUSTAIN-6 [Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes]) showed very promising results regarding the prevention of CVD. In this review, I discuss some of these new antidiabetic agents and present clinical information regarding these drugs.
김두만 대한의사협회 2008 대한의사협회지 Vol.51 No.9
The incidence of type 2 diabetes mellitus is increasing rapidly worldwide, primarily because of increases in obesity and decreases in physical activity. Type 2 diabetes is one of the leading problems for the health-care system. In South Korea type 2 diabetes affects approximately 7~8% of adults. Some risk factors of type 2 diabetes mellitus such as overweight, nutritional imbalance, and a sedentary lifestyle are reversible. To prevent type 2 diabetes two approaches are usually adopted. One is population strategy that is aimed at preventing obesity, and the other is high-risk strategy to prevent and delay the development of type 2 diabetes in high risk groups. Prevention of type 2 diabetes is backed by many research evidences like Finnish Diabetes Prevention Study (Finnish DPS) and Diabetes Prevention Program (DPP) of USA. In this article I discuss the results of Finnish DPS and DPP, and to propose the prevention strategy in South Korea.