말티즈견에서 발생한 승모판폐쇄부전 1례

전소분,박혜연,김선아,정금선,이영원,박성준,김덕환,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A 10 years old, intact male, Maltese dog with clinical signs of labored respiration, exercise intolerance and increasing of coughing was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Physical examination revealed tachycardia, panting and mild cyanosis. This case was diagnosed as mitral valve insufficiency by clinical signs, ascultation, blood chemistry, radiography and electrocardiography. This dog was treated with ACE inhibitor (enalapril), diuretics (furosemide) and bronchodilator (aminophylline) for 14 days. After treatment, clnical signs were disappeared and also this dog was needed to be continuous monitoring and sodium restricted diet.

미혼 남녀의 개인적, 관계적, 상황적 변인이 데이팅 폭력에 미치는 영향

손혜진,전귀연 대한가정학회 2003 Family and Environment Research Vol.41 No.2

The purpose of this study is to investigate how much individual. relational, and contextual variables have an effect on the dating violence of premarital males and females. Researched are 369 male and female residents over 19 years have experienced dating or were involved in any dating relationships in Daegu. The instruments of measurement are CTSⅡ scale and scales of relation to individual, relational, and contextual variables. The data are analysed through factor analysis, Cronbach'sα, frequency, percentile, and stepwise regression analysis. The major findings of this study are as follows: First, individual variables that affect doing and victimization of dating violence are one's permission degree of dating violence, and psychologica abuses experienced during childhood from one's mother. Second, relational variables that affect doing and victimization of dating violence are control toward one's partner, communlcation, conflict, commitment, intimacy, satisfaction of dating relationship, and feeling of inferiority toward one's partner. Third, contextual variables that affect doing and victimization of dating violence are familial relationships,friend relationships, and financial stresses.

여대생의 생활습관 및 스트레스가 변비에 미치는 영향

문지희,전혜연,강나영,김희정,배나영,양아롬,왕세미,하주영,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

The purpose of this research is to analyze relationships among the habitual life, stress, and constipation and to help prevent and improve the constipation among women's university students. This is a descriptive interrelated research that has targeted women's university students. The data had been collected for 10 days, from December 22, 2003 to December 31, 2003. The survey was carried out to the 295 women's university students that had been randomly selected by visiting four-year-course colleges and universities in Seoul. The survey consists of 78 questions: five questions on the general trait, 11 questions on the habitual life, 51 questions on the stress, and 11 questions on the constipation. There are seven questions on the dietary life, four questions on exercising, and Shin Jung Ran's survey(2003) and Lee Ji Jung's survey(2001) was used as a reference. Yoon Ho Yul's five grade stress barometer(1996) was also used to measure the amount of stress. The collected data was analyzed by a real number, percentage, the arithmetical mean, the standard deviation, t-test, x²test using SPSS 10.00 for Windows Program. Results are as follow 1. Four to six cups of daily water intake was the highest by 50.0%. Students not have breakfast(55.7%) mostly because they did not have enough time(62.6%). Dinner was the most overeated meal by 72.3% and the most preferred food was meat by 42.0%. In the questions related to exercising, more than half of the students answered that they hardly do not exercise(58%), work out for less than 30minutes(67.3%), and exercised lightly(75.3%). 2. Students were suffering from stresses due to the personal relations(51.36±14.0426), scholastic achievement and personal direction(24.93±8.3037), financial conditions and family matters(20.28±8.1718) and social circumstances(2.7262). 3. In the defection part, the student's reply that they have more than five times of bowel movement on a weekly basis(48.3%), and that it takes three to five minutes to defecate(41.3%) were the highest. More than half of the students answered that their one time excrement quantity was between 30 grams to 60 grams(72.3%) and that it was normal(68.7%). In a question asking how it feels after the defecation(students were allowed to choose more than one answer), relieved and refreshed was the highest by 66.6%, an uncomfortable followed by 42.8%. 4.4% of the students answered that they suffer from strong abdominal pain during the defecation. The rest of the students answered that they do not have stomachache or that it was normal. The students were classified into the constipation group of 103 people(34.9%) and the normal group of 192 people(65.1%) under the devised definition of this research. 4. Students that live in dormitories and do their own cooking were more likely to have constipation than those that live in private residence or in a lodgins. 5. The research showed that there is a mutual relation between water in a day intake and the constipation. It means that the lesser water students drink, the more they suffer from the constipation. The number of times a student had a meal everyday and the constipation was interrelated. If a student had lesser or irregular meals in a day, they had more constipation. Preferred food and constipation was also interrelated. Students that preferred vegetable, fruit, and dairy products were more likely to belong in a normal/general group. 6. By dividing the stress factors into the lower categories, we were able to see that the total stress(t-2.063, p-0.040), personal relations(t-2.316, p-0.021), scholastic achievements and personal directions(t-20127, p-0.034) had mutual relation with the constipation. The constipation group(120.27±30.2708) was suffering from stronger level of stress than the normal group(112.97±28.1466). Through this study, we were able to verify that the few general traits, habitual life, and stress of the women's university students have mutual relations with the constipation.

Impact of Antiviral Therapy on Risk Prediction Models for Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B

( Hye Yeon Chon ),( Tae Seop Lim ),( Mi Young Jeon ),( Hye Won Lee ),( Beom Kyung Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang-hyub Han ),( Seung Up Kim ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Risk prediction models for hepatocellular carcinoma (HCC) development have been proposed. However, the influence of antiviral therapy (AVT) on these models in patients with chronic hepatitis B (CHB) is unknown. Methods: We investigated the dynamics of risk prediction models during AVT and the association between on-treatment values from these models and the risk of HCC development. Results: Between 2005 and 2017, 6,098 patients with CHB (1,758 non-cirrhotic, 4,340 cirrhotic) in whom AVT was initiated with entecavir (n=3,818) or tenofovir (n=2,280) were recruited. The mean age of the study population was 49.1 years and 61.4% (n=3,742) of the patients were male. The mean CU-HCC value was 12.7 at baseline in the entire study population; it was significantly lower (mean, 8.6) after 1-year of AVT (P< 0.001) and was maintained throughout 5-years of AVT (mean, 8.2-8.4; P >0.05). The proportion of high-risk patients (CU-HCC score ≥ 20) was 28.9% at baseline, which significantly decreased after 1-year of AVT (4.8%; P< 0.001) and was then maintained through 5-years of AVT (2.6-3.5%; P >0.05). The CU-HCC score after 1-year of AVT independently predicted the risk of HCC development (hazard ratio=1.037), together with age, male gender, liver cirrhosis, and platelet count (all P<0.05). Similar findings were obtained when the REACH-B criteria were used for non-cirrhotic patients. Conclusions: CU-HCC and REACH-B scores were significantly lower after 1-year of AVT and were maintained thereafter. CU-HCC and REACH-B scores after 1-year of AVT independently predicted the risk of HCC development in patients with CHB in whom AVT was initiated.

Cloning and Identification of Novel Maltose Generating α-amylase from Lactobacillus plantarum subsp. plantarum ST-III

Hye-Yeon Jeon,Hye-Won Lee,Hye-Jeong Choi,Jae-Hoon Shim 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Characterization of a Novel Maltose-Forming α-Amylase from <i>Lactobacillus plantarum</i> subsp. <i>plantarum</i> ST-III

Jeon, Hye-Yeon,Kim, Na-Ri,Lee, Hye-Won,Choi, Hye-Jeong,Choung, Woo-Jae,Koo, Ye-Seul,Ko, Dam-Seul,Shim, Jae-Hoon American Chemical Society 2016 Journal of agricultural and food chemistry Vol.64 No.11

<P>A novel maltose (G2)-forming alpha-amylase from Lactobacillus plantarum subsp. plantarum ST-III was expressed in Escherichia coli and characterized. Analysis of conserved amino acid sequence alignments showed that L. plantarum maltose producing alpha-amylase (LpMA) belongs to glycoside hydrolase family 13. The recombinant enzyme (LpMA) was a novel G2 producing alpha-amylase. The properties of.purified LpMA were investigated following enzyme purification. LpMA exhibited optimal activity at 30 degrees C and pH 3.0. It produced only G2 from the hydrolysis of various substrates, including maltotriose (G3), maltopentaose (GS), maltosyl beta-cyclodextrin (G2-beta-CD), amylose, amylopectin, and starch. However, LpMA was unable to hydrolyze cyclodextrins. Reaction pattern analysis using 4-nitrophenyl-alpha-D-maltopentaoside (pNPGS) demonstrated that LpMA hydrolyzed pNPGS from the nonreducing end, indicating that LpMA is an exotype alpha-amylase. Kinetic analysis revealed that LpMA had the highest catalytic efficiency (k(cat)/K-m ratio) toward G2-beta-CD. Compared with beta-amylase, a well-known G2-producing enzyme, LpMA produced G2 more efficiently from liquefied corn starch due to its ability to hydrolyze G3.</P>

Can common carotid artery ultrasonography help in screening high-risk pregnant women?

( Moon Hye Yeon ),( Park Hyeon Ji ),( Jeon Hye Jin ),( Kwan Heup Song ),( Ho Yeon Kim ),( Geum Joon Cho ),( Ki Hoon Ahn ),( Soon Cheol Hong ),( Min Jeong Oh ),( Hai Joong Kim ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-

Objective: Pregnancy at advanced maternal age has become more common in Korea. There are many studies between pregnancy induced complication such as pre-eclampsia, gestational diabetes mellitus (GDM) and advanced maternal age. Therefore, screening for high-risk pregnant women with pregnancy induced complications is important. Carotid intima-media thickness (CIMT) and peak systolic velocity (PSV) are well known indicators of atherosclerosis and cardiovascular disease. CIMT and PSV are affected by endothelial dysfunction and inflammation. This is similar to the mechanism that causes placental dysplasia and vascular disorders, leading to pregnancy induced complication. In this study, CIMT and PSV were compared between high-risk pregnant women and normal pregnant women. Methods: This study had been performed at Korea University Ansan Hospital between March 2019 and August 2022. All enrolled women measured CITM, PSV, and end-diastolic velocity by ultrasonography between 20 and 24 weeks of gestation. In addition, perinatal complications, clinical characteristics, delivery method, gestation age, birth weight of the fetus, neonatal intensive care unit administration, and Apgar score were compared among these pregnant women. Results: Maternal common carotid artery (CCA) IMT and PSV did not show a significant correlation with overt diabetes mellitus (DM) and GDM. However, pregnant women with pregnancy induced hypertensive disorder (PIH) showed decreased the PSV of CCA that compared to normal pregnant women. (p=value 0.043) In addition, CCA IMT showed a positive correlation with gestational age and birth weight. (p-value 0.02, 0.028 / r-value 0.277, 0.2262) Conclusion: In pregnant women with PIH, the PSV of CCA was decreased compared to normal pregnant women. This may help screening pregnant women who had high risk for PIH in the second trimester of pregnancy.

불안 장애, 우울 장애 및 정신증 환자군의 지적 기능 비교

전혜연(Hye-Yeon Jeon),박은희(Eun-Hee Park),전덕인(Duk-In Jon) 대한스트레스학회 2010 스트레스硏究 Vol.18 No.4

본 연구는 불안 장애 환자, 우울 장애 환자와 정신증 환자군의 지적 기능의 특성을 K-WAIS를 중심으로 살펴보았다. 불안 장애 47명, 우울 장애 56명과 정신증 62명을 대상으로 K-WAIS의 결과를 연령과 교육년수를 통제하고 MANCOVA를 실행하였다. 그 결과, 불안 장애 환자군이 우울 장애 환자군과 정신증 환자 장애군에 비하여 숫자 외우기 소검사에서 유의미하게 높은 점수를 받았다. 불안 장애 환자군과 우울 장애 환자군에 비하여 정신증 환자군이 산수 소검사, 동작성 지능과 주의지속능력 요인에서 유의미하게 낮은 수행을 보였다. 또한 정신증 환자군은 이해문제, 차례 맞추기, 모양 맞추기, 바꿔쓰기 소검사와 언어성 지능, 전체 지능, 지각적 조직화 요인에서도 불안 장애 환자군에 비하여 유의미한 수준으로 저조한 수행을 보이고 있었다. 세 집단의 지적 기능에서 유의한 차이를 보인 본 연구의 결과는 각 장애의 일상생활 기능의 손상 정도를 예측할 수 있게 해주는 중요한 정보가 될 수 있을 것으로 생각된다. This study was investigated about the characteristics of intellectual functions among patients with anxiety, depressive and psychotic disorder on the Korean-Wechsler Adult Intelligence Scale (K-WAIS). The participants were 47 patients with anxiety disorder, 56 patients with depressive disorder, and 62 patients with psychotic disorder. The data were statistically analyzed using multivariate analysis of covariance (MANCOVA) controlling for age and educational level. It was found that the anxiety disorder group acquired significantly higher scores in digit span subtest than the depressive disorder and psychotic disorder groups. The psychotic disorder group acquired significantly lower scores in arithmetic subtest, performance IQ, Freedom from Distractibility factor than the anxiety and depressive disorder groups. Moreover, the psychotic disorder group scored significantly lower in several subtests (comprehension, picture arrangement, object assembly, and digit symbol), verbal and full scale IQ, and perceptual organization factor than the anxiety disorder group. The result suggests that the three clinical groups are differential differences in terms of intellectual abilities. It implicates the probability that it would reflect the differences of functional level in everyday life in each group. (Korean J Str Res 2010;18:353∼362)

살포 방법에 의한 살균제 Dithianon의 감귤 잎 부착량 비교

전혜원(Hye-Won Jeon),홍수명(Su-Myeong Hong),현재욱(Jae-Wook Hyun),황록연(Rok-Yeon Hwang),권혜영(Hye-Young Kwon),김택겸(Taek-Kyum Kim),조남준(Nam-Jun Cho) 한국농약과학회 2016 농약과학회지 Vol.20 No.1

Quantitative Vertebral Bone Density Seen on Chest CT in Chronic Obstructive Pulmonary Disease Patients: Association with Mortality in the Korean Obstructive Lung Disease Cohort

Hwang Hye Jeon,이상민,Seo Joon Beom,Kim Ji-Eun,Choi Hye Young,Kim Namkug,Lee Jae Seung,Lee Sei Won,Oh Yeon-Mok 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.7

Objective: Patients with chronic obstructive pulmonary disease (COPD) are known to be at risk of osteoporosis. The purpose of this study was to evaluate the association between thoracic vertebral bone density measured on chest CT (DThorax) and clinical variables, including survival, in patients with COPD. Materials and Methods: A total of 322 patients with COPD were selected from the Korean Obstructive Lung Disease (KOLD) cohort. DThorax was measured by averaging the CT values of three consecutive vertebral bodies at the level of the left main coronary artery with a round region of interest as large as possible within the anterior column of each vertebral body using an in-house software. Associations between DThorax and clinical variables, including survival, pulmonary function test (PFT) results, and CT densitometry, were evaluated. Results: The median follow-up time was 7.3 years (range: 0.1–12.4 years). Fifty-six patients (17.4%) died. DThroax differed significantly between the different Global Initiative for Chronic Obstructive Lung Disease stages. DThroax correlated positively with body mass index (BMI), some PFT results, and the six-minute walk distance, and correlated negatively with the emphysema index (EI) (all p < 0.05). In the univariate Cox analysis, older age (hazard ratio [HR], 3.617; 95% confidence interval [CI], 2.119–6.173, p < 0.001), lower BMI (HR, 3.589; 95% CI, 2.122–6.071, p < 0.001), lower forced expiratory volume in one second (FEV1) (HR, 2.975; 95% CI, 1.682–5.262, p < 0.001), lower diffusing capacity of the lung for carbon monoxide corrected with hemoglobin (DLCO) (HR, 4.595; 95% CI, 2.665–7.924, p < 0.001), higher EI (HR, 3.722; 95% CI, 2.192–6.319, p < 0.001), presence of vertebral fractures (HR, 2.062; 95% CI, 1.154–3.683, p = 0.015), and lower DThorax (HR, 2.773; 95% CI, 1.620–4.746, p < 0.001) were significantly associated with all-cause mortality and lung-related mortality. In the multivariate Cox analysis, lower DThorax (HR, 1.957; 95% CI, 1.075–3.563, p = 0.028) along with older age, lower BMI, lower FEV1, and lower DLCO were independent predictors of all-cause mortality. Conclusion: The thoracic vertebral bone density measured on chest CT demonstrated significant associations with the patients’ mortality and clinical variables of disease severity in the COPD patients included in KOLD cohort.