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      • KCI등재후보

        사상채질 분류를 위한 안면부내 특징 요소 추출

        배나영,안택원,조동욱,이화섭,Bae, Na-Yeong,An, Taek-Won,Jo, Dong-Uk,Lee, Hwa-Seop 사상체질의학회 2005 사상체질의학회지 Vol.17 No.2

        1. Objectives The purpose of this study is to objectify the diagnosis of Sasang Constitution. Using the methods of this study, it will improve to classificate Sasang Constitution. 2. Methods 1) Automatic feature extraction of human frontal faces for Sasang Constitution classification. 2) Color feature extraction of human frontal faces (1)Erosion filtering (skin-white, the other-black) (2) Median median 3. Results and Conclusions Observing a person's shape has been the major method for Sasang Constitution classification, which usually has been dependent upon doctor's intuition as of these days. We are developing an automatic system which provides objective basic data for Sasang Constitution classification. For this, in this paper, firstly, the signal processing techniques are applied to automatic feature extraction of human frontal faces for Sasang Constitution classification. The experiment is conducted to verify the effectiveness of the proposed system.

      • KCI등재

        석면 오염 토양의 위해성평가 방법 연구

        배나영,정명채,차종문 한국자원공학회 2016 한국자원공학회지 Vol.53 No.1

        Asbestos is a set of six naturally occurring silicate minerals exploited commercially for their desirable physical properties. Asbestos can cause or contribute to an increased incidence of asbestosis, lung cancer and mesothelioma. The purpose of this study is to evaluate the asbestos exposure in soil using Modified Asbestos-Related Risk (MARR) and Excess Life Cancer Risk (ELCR). From the result of risk assessment based on MARR and ELCR in the soils contaminated with tremolite, MARR had 1.74 times higher than ELCR. On the other hand, concerning asbestos risk, the results from the risk assessment in the soils contaminated with chrysotile showed that ELCR had 25 times higher than MARR result. Therefore it would be more reasonable to undertake the risk assessment of asbestos according to the type of asbestos. 석면은 석면상(asbestiform)으로 산출되는 규산염 광물이다. 풍화작용에 의해 비산된 석면 입자들이논과 밭 등을 오염시키게 되면서 석면 흡입에 대한 석면성 질병에 대한 위해성 문제가 대두되고 있다. 본 연구에서는 석면 오염 토양에서의 석면 비산성 실험을 수행하고 ELCR (Excess Life Cancer Risk)와 MARR (Modified Asbestos-Related Risk)를 이용하여 백석면 오염 토양과 투각섬석 오염 토양에서의 위해성 평가를 각각 수행하였다. 그 결과 투각섬석으로 오염된 토양에서의 위해성 평가 비교 결과 MARR의 결과가 ELCR보다 약 1.7배 크게나왔고, 사문석으로 오염된 토양에서 MARR의 결과가 ELCR에 비해 작은 위해도(4%)를 가진 것으로 나타났다. 그러므로 투각섬석으로 오염된 토양과 백석면으로 오염된 토양에서의 위해성 평가는 구분하여 진행되는 것이더 합리적일 것으로 판단된다.

      • KCI등재

        사상체질병증 임상진료지침: 예방 및 위험인자

        배나영,이의주,Bae, Na-Young,Lee, Eui-Ju 사상체질의학회 2015 사상체질의학회지 Vol.27 No.1

        Objectives This research was proposed to present Clinical Practice Guideline (CPG) for Prevention of Sasangin disease pattern of Sasang Constitutional Medicine (SCM) and diseases closely related with Sasang constitution. Each CPG was developed by the national-wide experts committee consisting of SCM professors. Methods At first, we searched the literatures related to SCM such as "Dongeuisusebowon", Textbook of SCM and Clinical Guidebook of SCM. Also we searched the articles related to the studies about risk factors for Sasangin disease pattern of both at home and abroad. Finally, we selected leading risk factors of Sasangin disease pattern and developed CPG for prevention of Sasangin disease pattern of SCM. And then, we searched the literatures related SCM such as "Dongeuisusebowon" and the articles on the correlation between disease and Sasang constitution using case-control studies, observational studies or cross sectional studies of both at home and abroad. Next, we selected diseases closely related with Sasang constitution on the basis of articles including prevalence rate and odds ratio between disease and Sasang constitution and finally developed CPG for these diseases. Results and Conclusions We categorized risk factors of Sasang disease pattern into 2 types: non-modifiable and potentially modifiable. 3 items (age, sex and genetic factors) were classified as non-modifiable risk factors of Sasang disease pattern. 6 items (original symptom, stress, diet and nutrition, physical activity, alcohol and drug misuse) were classified as less well-documented or potentially modifiable risk factors of Sasangin disease pattern. We found out Sasang constitution is more likely to develop some diseases. It was proven that Sasang constitution increase the risk of hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. And there is high probability of Sasang constitution being potential risk factor for obesity, hyperlipidemia, allergy and cancer. Also, we found out Taeeumin is independent risk factor for hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. Therefore we recommend that Taeeumin need to prevent these disease by regular checkups and aggressive management.

      • 청소년의 우울이 자살생각에 미치는 영향에서 종교적 신념과 개인통제력의 조절효과

        배나영 한국인간복지실천학회 2012 한국인간복지실천연구 Vol.8 No.-

        본 연구는 청소년의 우울이 자살생각에 미치는 영향에 대해서 살펴보고, 우울이 자살생각에 미치는 영향에서 종교적 신념과 개인통제력의 조절효과를 살펴보고자 하였다. 이를 위해서 서울시의 2개 구에 거주하는 청소년 총 409명을 대상으로 설문조사를 실시하였다. 수집된 자료는 SPSS 17.0 프로그램을 사용하여 연구문제를 검증하였다. 연구 결과는 첫째, 청소년의 우울이 자살생각에 영향을 미치는 요인으로 나타났다. 둘째, 청소년의 우울이 자살생각에 미치는 영향에서 종교적 신념이 조절효과가 있는 것으로 나타났다. 셋째, 청소년의 우울이 자살생각에 미치는 영향에서 개인통제력이 조절효과가 있는 것으로 나타났다. 즉, 청소년의 우울이 자살생각에 미치는 영향에서 종교적 신념과 개인통제력이 조절효과가 있는 것으로 나타났다. This study is to look into the influence of the depression of adolescent on the thought of suicide and to look into the adjusting effect of religious persuasion and personal control in the influence of depression on the thought of suicide. To do this, for the participants of total 409 persons of adolescents who reside in the 2 boroughs of Seoul, a survey was carried out. With the collected materials SPSS 17.0 program was used to verify the subject for inquiry. The research results were: First, the depression of adolescents appeared to be a primary cause which has influence on the thought of suicide. Second, in the influence of the depression of adolescents on the thought of suicide, religious persuasion appeared to have adjusting effect. Third, in the influence of the depression of adolescents on the thought of suicide personal control appeared to have adjusting effect. In other words, in the influence of the depression of adolescents on the thought of suicide, religious persuasion and personal control appeared to have adjusting effect.

      • KCI등재

        β-Amyloid로 유도된 신경독성에 대한 熱多寒少湯 加感方의 抗치매효과

        배나영,양현옥,안택원 사상체질의학회 2009 사상체질의학회지 Vol.21 No.3

        1. Objectives Yeolda-Hanso tang (YH) has long been used as traditional herbal formula in Korea as various diseases. Now we modified Yeolda-Hanso tang (YH) for neurodegenerative diseases treatment and named New-Yeolda-Hanso tang (NYH). We investigated neuroprotective effects of NYH on NGF-differentiated PC12 cells cytotoxicity induced by β-Amyloid peptide (Aβ25-35) and evaluated the ability of NYH to prevent and treat for neurodegenerative diseases via autophagy enhancement. 2. Methods and Results 1) Protective effect of NYH on PC12 cells cytotoxity induced by Aβ25-35. PC12 cells survival was measured by MTT and lactate dehydrogenase (LDH) assay. 20μΜ β-Amyloid peptide (Aβ25-35) induced cytotoxicity on NGF-differentiated PC12 cells. NYH attenuated the cytotoxic effects of Aβ25-35 in a dose-dependent manner. 2) Pharmacological induction of Autophagy by NYH in PC12 cells Autophagy induction and activation was measured by immunoblot assay. Marker of autophagy, LC3Ⅱ expression and the ratio of LC3-II/I was slightly increased in the protein treated with YH, and significantly augmented in the protein treated with NYH. NYH-induced increase of LC3-II protein level was inhibited by 3MA. 3) Induction of Autophagy by NYH on Aβ25-35-induced injury in PC12 cells In MTT assay, 100㎍/㎖ pre-treated NYH attenuated 20μΜ Aβ25-35-induced cytotoxicity in PC12 cells. Protection effect of NYH was blocked by autophagy inhibitor 3MA. In immunoblot assay, 1200㎍/㎖ pre-treated NYH activated autophagy in 20μΜ Aβ25-35-induced cytotoxicity in PC12 cells. The observed effect was partially blocked by 3MA. 3. Conclusions All the results indicated that NYH possesses neuroprotective potential partially mediated by autophagy enhancement and NYH may be considered to be a promising new herbal formula to prevent and treat for neurodegenerative diseases including Alzheimer's disease (AD).

      • KCI등재

        녹용대보탕(鹿茸大補湯)이 AAPH로 유발된 산화병태(酸化病態)모델 흰 쥐의 항산화(抗酸化) 작용(作用)에 미치는 영향

        배나영,안택원,Bae, Na-Young,Ahn, Taek-Won 사상체질의학회 2007 사상체질의학회지 Vol.19 No.2

        1. Objectives This study aimed to investigate the anti-oxidative effect of Nocyongdaebo-tang (NYD) decoction in oxidized rats induced by AAPH. 2. Methods AAPH (2.2-azobis-2 aminodinopropane-hydrochloride) was injected intraperitoneally to induce oxidization and NYD was orally administered to the rats. To observe the anti-oxidative effect of NYD, we performed blood chemistry analysis, histological analysis, and evaluated the levels of SOD, catalase, glutathione, NO and MDA in liver. 3. Results & Conclusions 1) Serum Albumin level was increased significantly in the NYD group as compared with the control group and the saline group. 2) Serum LDL-cholesterol level was reduced significantly in the NYD group as compared with the control group. 3) GPT level in liver was reduced significantly in the NYD group as compared with the control group. 4) SOD, catalase activity and glutathione levels were increased significantly in the NYD group as compared with the control group and the saline group. 5) The levels of NO and MDA were reduced significantly in the NYD group as compared with the control group. 6) The degenerative change of liver tissue of NYD group was decreased in comparison with the control group. In conclusion, NYD decoction is considered to have an anti-oxidative effect in rats.

      • KCI등재후보

        심혈관계 질환의 위험인자와 사상체질 사이의 연관성 및 활성산소가 이에 미치는 영향에 대한 임상적 연구

        한경수,배나영,이한얼,안택원,Han, Kyung-Su,Bae, Na-Young,Lee, Han-Eol,Ahn, Taek-Won 사상체질의학회 2007 사상체질의학회지 Vol.19 No.2

        1. Objectives The purpose of this study was to prove the correlation between risk factor of cardiovascular disease and Sasang Constitution and to investigate the effect of oxygen free radical on this correlation. 2. Methods We analyzed 129 patients who visited Cheonan oriental medical hospital from Apr 1, 2007 until May 31, 2007, for medical examination, which Includes Sasang Constitution examination, blood chemistry test and physical examination. And we classified their results into 4 groups based on with blood lipoprotein level and body mass index. 3. Results and Conclusions Mean of lipoprotein in blood was not significantly different among constitutions but with body mass index, was significantly higher in Taeumin than others. And count of dyslipoproteinemia was significantly higher in Taeumin group than soeumin. Therefore, according to our results, risk of cardiovascular disease was higher in Taeumin than other constitutions. Oxygen free radical did not have much effect on correlation between risk factor of cardiovascular disease and Sasang Constitution. However, there was some evidence in soeumin group, that oxygen free radical may have effect on origination of hyperlipidemia.

      • KCI등재

        조위승청탕(調胃升淸湯)으로 호전된 올리브교소뇌위축증 환자 1례

        이미숙,배나영,Lee, Mi-Suk,Bae, Na-Young 사상체질의학회 2013 사상체질의학회지 Vol.25 No.3

        Objectives The aim of this study was to examine significant improvement of dizziness, gait disturbance, insomnia and xerostomia after treatment with Jowisengcheong-tang in a Taeeumin patient with olivopontocerebellar atrophy (OPCA). Methods The patient's subjective and objective symptoms were observed daily throughout the hospitalization period using global assessment (G/A), and the Unified Multiple System Atrophy Rating Scale (UMSARS) was used to assess the overall function of patient. Results The symptoms of dizziness and xerostomia decreased from G/A 100 to G/A 10~30 for five days, and the UMSARS score decreased in Part I,II. Conclusions This case showed that Sasang constitutional medicine treatment can be effective treatment method for OPCA. We consider that consistent treatment can contribute to improve the patient's quality of life.

      • KCI등재

        수화기제탕(水火旣濟湯) 증류액이 노화 흰쥐의 비장세포 면역활성에 미치는 영향

        최재송,배나영,안택원,Choi, Jae-Song,Bae, Na-Young,Ahn, Teak-Won 사상체질의학회 2011 사상체질의학회지 Vol.23 No.3

        1. Objectives: The purpose of this study is to investigate the effect of Suhwagije-tang(SGT) distillate on the immune activity of spleen cells of aged SD rats. 2. Methods: We used 10, 50, 72 weeks old SD rats in this study. Spleen cells from SD rats were stimulated with ConA and treated with 1% Vitamin C(Vit.C) or Suhwagijetang distillate(SGT). After 24 hours, the concentrations of IL-2, IL-4, IL-10, IFN-${\gamma}$ in the cell culture supernatant were measured by ELISA. 3. Results and Conclusions 1) At all concentration of SGT distillate, survival rates of liver cells were higher than the control group. In addition, 50% SGT distillate group's cell survival rates were significantly higher than other groups. 2) In 10 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group, Vit.C group. In 52 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group. 3) In 10, 52 weeks SD rats(SGT group), the concentration of IL-4 significantly decreased in comparison with ConA group. 4) In 10 weeks SD rats(SGT group), the concentration of IL-10 significantly decreased in comparison with ConA group. And in 72 weeks SD rats(SGT group), the concentration of IL-10 significantly increased in comparison with Vit.C group. 5) In 52, 72 weeks SD rats(SGT group), the concentration of IFN-${\gamma}$ significantly decreased in comparison with 10 weeks SD rats(SGT group). These results suggest that Suhwagije-tang(SGT) distillate has the effect of increasing the immune activity of spleen cells of aged SD rats.

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