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      • 소규모사업장 보건관리기술지원사업 지원여부에 따른 사업장내 의사소통 비교

        정최경희,박혜숙,김정연,이경용,현성민,오지영,김수근,김현주,하은희 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

        목적: 소규모사업장 보건관리기술지원사업 지원여부에 따라 사업장내 위험의사소통채널이 마련되었는지와 이 채널이 기능을 하는지, 그리고 의사소통채널마련과 사업장내 위험의사소통 활성화의 기본적이고 중요한 배경이 되는 사업주의 산업보건에 대한 관심이 차이가 있는지에 대해 살펴보고자 하였다. 방법: 서울, 안산, 대전, 광주, 포항 지역에서 보건관리기술지원사업을 받은 사업장과 받지 않은 사업장을 대상으로 비례층화무작위표본추출법을 사용하여 추출한 후 1991년 12월 6일부터 10일간 우편설문조사를 실시하였다. 설문대상은 각 사업장의 남녀 각 1명, 보건업무담당자, 사업주였으며, 설문내용은 사업장 및 응답자의 일반적 특성 및 사업장내 위험의사소통이었다. 설문에 응답이 온 463개 사업장의 자료를 자료처리하여 총 228개 사업장(단해년도지원 사업장 189개, 연속2년지원 사업장 13개, 비지원사업장 26개)을 대상으로 분석하였다. 결과: 사업장내 의사소통에 대한 단변량분석에서는 보건업무 담당자의 선정여부만이 통계적으로 유의한 차이가 있었다. 소규모사업장 보건관리기술지원사업을 지원받지 않은 사업장과 지원받은 사업장의 사업장내 위험의사소통을 비교하기 위한 로지스틱회귀분석 결과, 모든 항목에서 통계적으로는 유의한 차이를 보여주지 않았다. 그러나 사업주의 관심(OR ; 1.63, 95% CI ; 0.38~7.01)과 보건업무담당자의 선정(OR ; 3.67, 95% CI ; 1.00~13.44) 및 결정권한(OR ; 1.48, 95% CI ; 0.25~8.91), 사업주의 산업보건문제 소통(OR ; 3.07, 95% CI ; 0.81~11.71), 보건업무담당자의 정보요청경험(OR; 4.48, 95% CI ; 0.97~20.57)에서는 지원받지 않은 사업장에 비해 지원받은 사업장에서 교차비가 증가하는 양상을 보여주었다. 반면 노동자의 산업보건문제 소통가능성여부는 오히려 교차비가 0.53(95% CI ; 0.11~2.44)로 감소하는 경향을 보여주었다. 결론: 소규모사업장 보건관리기술지원사업을 의사소통의 측면에서 평가해보면, 사업주나 보건업무담당자에게는 다소 효과가 있었지만 노동자가 지속적으로 참여할 수 있도록 의사소통문화를 바꾸어내는 데에는 한계가 있었다. 개선을 위해서는 노동자 중심의 접근 프로그램의 개발 및 시행이 시급하다 할 수 있다. Objectives :This study was to evaluate the effectiveness of the government-funded subsidized occupational health program for small-scale enterprises(GSOHP_SSE) by occupational health com-munication in workplace. Methods : We sampled the 1,835 enterprises of study by proportional stratified random sampling among industries of supported and not supported by GSOHP_SSE in Seoul, Ansan, Daejeon, Kwang-joo and Pohang. Information on the general characteristics of enterprises and respondants and occupational health communication in the workplace was collected on self-reported questionnaires by post-survey between December 6 and 15 in 2001. We received answers from 463 enterprises and analyzed 228 enterprises through data-cleaning by logistic regression to evaluate effectiveness of GSOHP-SSE about occupational health communication in the workplace. Results : By multiple logistic regression analysis, GSOHP_SSE turned out not to be statistically significant factor in all dependent variables about occupational health communication in the work-place. The concern of owner(odds ratio (below OR) ; 1.63, 95% confidence interval(below 95% CI) ; 0.38-7.01), formation(OR ; 3.67, 95% CI ; 1.00-13.44) and empowerment(OR ; 1.48, 95% CI ; 0.25-8.91) of health manager, request about occupational health problem of health manager(OR ;4.48, 95% CI ; 0.97-20.57) and occupational health communication of owner (OR ; 3.07, 95% CI ; 0.81-11.71) had the trend increasing OR in the industries supported GS-OHP_SSE relative to the industries not supported. But in recognition of possibility on occupational health communication of laborers, OR of GSOHP_SSE was decreased in 0.53(95% CI ; 0.11-2.44). Conclusions: This study found that the GSOHP_SSE was some effective to the side of employer and health manager, but had a limitation about change of communication culture useful to the laborers. We suggested the laborer-centered health training programs or the empowerment-based health training programs for effective occupational health management in the workplace.

      • Mono-, Di-fluoro 5, 10, 15, 20-tetraphenylporphyrin Iron(Ⅲ)의 분광학적 연구

        이인숙,신지영,김소영,김경아,김혜균 서울여자대학교 자연과학연구소 1997 자연과학연구논문집 Vol.8 No.-

        Resonance Raman(RR) spectra of 5,10, 15, 20-tetraphenylporphyriniron(III) difluoride, [Fe(TPP)F_2], which was formed by the reaction between Fe(TPP)Cl and tetrabutylammonium fluoride(TBAF 3H_2O) in various non-aqueous solvents, were obtained with the 441.6nm(He-Cd laser) excitation. [Fe(TPP)F_2] is six-coordinate iron porphyrin with two polar Fe-F bonds. The porphyrin skeletal modes can be correlated with previously recorded mode of Ni(TPP) and [FeTPP]_2O. And these assignments were confirmed by observed wavenumber shifts due to ??Fe/^54Fe and TPP/TOO-d_8/TPP-N_15 isotopic substitutions. Difluoroiron complex is an iron(III) high-spin complex with the oxidation sensitive band at 1347cm^-1 for v_4 and core size/spin state sensitive band at 1541cm^-1 for v_2.

      • Helicobacter pylori와 대장균의 Shuttle Vector 개발

        조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

        In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

      • SCIESCOPUSKCI등재

        Efficacy of DA-9701 (Motilitone) in Functional Dyspepsia Compared to Pantoprazole: A Multicenter, Randomized, Double-blind, Non-inferiority Study

        ( Hye-Kyung Jung ),( Kwang Jae Lee ),( Myung-Gyu Choi ),( Hyojin Park ),( Joon Seong Lee ),( Poong-Lyul Rhee ),( Nayoung Kim ),( Kyung Sik Park ),( Suck Chei Choi ),( Oh Young Lee ),( Kyu Chan Huh ),( 대한소화기기능성질환·운동학회 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.2

        Background/Aims The effect of proton pump inhibitors (PPI) in Asian functional dyspepsia (FD) patients has not been well established as in Western countries. DA-9701, a novel prokinetic agent, stimulates gastric emptying and modulates visceral hypersensitivity in vivo and in human studies. This study was conducted to compare the efficacy of DA-9701 with a conventional PPI in mono or combination therapy in patients with FD. Methods In this double-blind, randomized, non-inferiority trial, 389 patients diagnosed with FD using Rome III criteria were allocated among 3 groups: 30-mg DA-9701 t.i.d (means 3 times a day), 40-mg pantoprazole, and 30-mg DA-9701 t.i.d + 40-mg pantoprazole. The primary efficacy end-point was a global assessment of the patient binary response or response on a 5-Likert scale after 4 weeks. Results The global symptomatic improvement was 60.5% in the DA-9701 group, 65.6% in the pantoprazole group, and 63.5% in the DA- 9701 + pantoprazole group using a 5-Likert scale at week 4 with no significant difference among 3 groups (P = 0.685). Symptom improvement measured by binary outcome was significantly achieved in each of the 3 groups, but not different among groups. Patients in all treatment groups reported significant improvement in the response rate and symptoms according to FD subtypes and dyspepsia-related quality of life (P < 0.001), but there were no significant differences among the 3 groups. Conclusions DA-9701 improves global and individual symptoms and increases dyspepsia-specific quality of life in patients with FD. The efficacy of DA-9701 monotherapy is comparable with pantoprazole and there is no additive effect with combination of DA-9701 and pantoprazole in patients with FD. (J Neurogastroenterol Motil 2016;22:254-263)

      • KCI등재후보

        A New FA Interspecific Hybrid Lily, "Eunbi" with Unspotted Light Orange Petals

        Hye Kyung Rhee,Jin Hee Lim,Hae Ryong Cho,Young Jin Kim 한국육종학회 2006 한국육종학회지 Vol.38 No.3

        2002. A cross was made betwen Lilium formolongi “Raizan”, a trumpet shaped and white petaled lily variety, and Lilium Asiatichybrid “A95-14”, a red colored variety. The flower characteristics and performance of “Eunbi” were investigated from 2000 tounder

      • An Asiatic Hybrid Lily ‘Joara’ with Unspotted Orange Petals

        Hye Kyung Rhee(이혜경),Hae Ryong Cho(조해룡),Jin Hee Lim(임진희),Mi Seon Kim(김미선),Seong Yeol Choi(최성렬) 한국원예학회 2008 한국원예학회 학술발표요지 Vol.2008 No.12

        ‘조아라’는 원예연구소에서 2005년에 육성된 절화용 아시아틱 나리 품종이다. 1997년 진한오렌지색 아시아틱 나리 ‘브루넬로(Brunello)’품종과 오렌지색 아시아틱 나리 ‘파사데나(Pasadena)’ 품종을 교배하여 종자를 획득하였고, 종자들을 파종, 육묘하여 개화후 ‘A00-59’계통으로 선발하였다. 이 계통은 조직배양에 의한 대량증식, 순화 및 양구를 거쳐 2003년부터 2005년까지 ‘원교C1-75호’로 특성검정을 수행하였다. ‘조아라’ 품종의 개화기는 6월 중순이다. 꽃은 상향 개화형이고, 꽃잎에 반점이 없으며, 진한 오렌지색이다. 식물의 초장은 81㎝이고, 꽃의 크기는 19.5㎝이다. 꽃의 화피장은 11.2㎝, 주년 재배를 위해서는 -1.5℃에 구근을 동결 저장하여 정식 시기를 달리하여 활용할 수 있다. An Asiatic hybrid lily cultivar ‘Joara’ was released in 2005 at National Horticultural Research Institute, Rural Development Administration of Korea. The cross was made in 1997 between L. Asiatic ‘Brunello’, orange colored, and L. Asiatic ‘Pasadena’, orange colored. It was preliminarily selected as ‘A00-59’ in 2000. It’s multiplication and bulbing, and growth and flowering characteristic tests were conducted from 2001 to 2005. The new cultivar ‘Joara’ flowers in the middle of June and grows to 81.1 ㎝ in height. Flowers bloom upward-facing, unspotted orange red petals (RHS, N30B). Year-round flowering is possible by storage of the bulb under -1.5℃ conditions. For forcing culture, it is necessary to add calcium to the fertilizer or remove side scales to prevent leaf scorch. Botrytis disease control is needed in the wet season.

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