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      • 사용자 인식 스마트 홈 미러

        최건영,고성화,김종옥,박은서,김완규,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

        The Internet of Things, the core of the Fourth Industrial Revolution, is growing by incorporating various technologies into various fields. Among them, smart home systems that apply IoT technology to home environments are being actively studied. The home hub market, a means of communication for smart homes, is also developing at the same time. As the home hub market develops, security threats are also increasing accordingly. In this paper, 'Smart Home Mirror' is implemented by combining mirror and IoT technologies so that users can use them to communicate with smart home applications and other devices. To meet security issues, users in it are recognized by using face recognition technology and AES between all data communications in it is applied. The proposed device’s usefulness is approved by implementing it in smart home environments.

      • 뇌하수체 종양 제거술 시행 후 뒤늦게 발생한 횡문근 융해증과 동반된 중추성 열

        장제혁,최규남,김일환,노은지,김윤정,유충헌,고정해,박봉수,김태균,권민정,이순희,박정현 인제대학교 2008 仁濟醫學 Vol.29 No.-

        Body temperature is controlled by thermoregulatory center of the hypothalamus. We report a case of 24 years old man with central fever. He was subjected to a partial excision of pituitary tumor compressing optic chiasm four years ago. He has received hormonal therapy for panhypothyroidism after removal of pituitary tumor. And He received gamma knife operation for partially contrast-enhancing masses in suprasellar and both hypothalamic areas that is probably postoperatively remnant or recurrent tumor of pituitary adenoma. One year after gamma knife operation, he presented with a febrile syndrome of unknown origin including rhabdomyolysis. All usual investigations proved negative. We diagnosed him as central fever with rhabdomyolysis. He received medical ICU care with cooling bed, ice pack. And his symptom improved. Postoperative hyperthermia may result following resection of the pituitary tumor. When central fever is suspected taking note of past history, a quick recognition of course of fever can help reduce the using of unnecessary antibiotics and hospital stay.

      • KCI등재

        편측성 완전 구순구개열 환자의 포괄적 치료

        이정근,황병남,최은주,김용빈 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.4

        Cleft lip and palate is one of the congenital anomalies which need comprehensive and multidisciplinary treatment plan because 1) oral cavity is an important organ with masticatory function as a start of digestive tract, 2) anatomic symmetry and balance is esthetically important in midfacial area, and 3) it is also important to prevent psycho-social problems by adequate restoration of normal facial appearance. There are many different protocols in the treatment of cleft lip and palate, but our department has adopted and modified the Z□rich protocol, as published in the Journal of Korean Cleft Lip and Palate Association in 1998. The first challenge is feeding. Type of feeding aid ranges from simple obturators to active orthopedic appliances. In our department we use passive-type plate made up of soft and hard acrylic resin which permits normal maxillary growth. We use Millard's method to restore normal appearance and function of unilateral complete cleft lip. In consideration of both maxillary growth and phonetic problems, we first close soft palate at 18 months of age and delay the hard palate palatoplasty until 4 to 5 years of age. When soft palate is closed, posterior third of the hard palate is intentionally not denuded to allow normal maxillary growth. In hard palate palatoplasty the mucoperiosteum of affected site is not mobilized to permit residual growth of the maxilla. We have treated a patient with unilateral complete cleft lip and palate by Ajou protocol, which is a kind of modified Z□rich protocol. It is as follows: Infantile orthopedics with passive-type plate such as Hotz plate, cheiloplasty with Millard's rotation-advancement flap, and two stage palatoplasty. It is followed by orthodontic treatment and secondary osteoplasty to augment cleft alveolus, orthognathic surgery, and finally rehabilitation with conventional prosthodontic treatment or implant installation. The result was good up to now, but we are later to investigate the final result with longitudinal follow-up study according to master plan by Ajou protocol.

      • 간세포암환자에서 간동맥 화학 색전술 후 발생한 리피오돌에 의한 폐렴 1예

        김소이,김유리,허현미,배서은,이명원,최윤정,김고흔,김태헌,유 권,문일환 이화여자대학교 의과대학 2009 EMJ (Ewha medical journal) Vol.32 No.2

        Hepatocellular carcinoma(HCC)is one of common causes of cancer-related death in Korea where the majority of HCC patients were Hepaitc B virus(HBV)carriers and have cirrhosis. Transarterial chemoembolization(TACE)is commonly applied to the treatment of multinodular HCC in Korea and careful selection of candidate is important for the risk of various side effects. Besides common side effects as fever, nausea, abdominal pain and elevation of liver enzyme, TACE may predispose to hepatic failure, ischemic cholecystitis, pulmonary embolism, cerebral embolism and pneumonitis. In previous studies, some cases of pulmonary and cerebral embolism cases were reported but lipiodol pneumonitis after TACE was rarely reported. A 65-year-old woman with a multinodular HCC associated with HBV infection, was treated with TACE. Seven days after the procedure, nonspecific respiratory symptoms such as dyspnea and dry cough developed. Chest X-ray and chest computed tomography showed diffuse ground glass opacities in whole lung fields, suggestive of lipiodol pneumonitis. After several days of supportive care with steroid administration, radiologic abnormalities and subjective symptoms were much improved, considered that the disease was compatible with lipiodol pneumonitis.

      • KCI등재
      • KCI등재

        Crosstalk Signaling between IFN-γ and TGF-β in Microglia Restores the Defective β-amyloid Clearance Pathway in Aging Mice with Alzheimer’s Disease

        Go-Eun Choi 대한의생명과학회 2018 Biomedical Science Letters Vol.24 No.4

        Microglia are emerging as critical regulators of innate immune responses in AD and other neurodegenerative disorders, highlighting the importance of understanding their molecular and cellular mechanisms. We attempted to determine the role of crosstalk signaling between IFN-γ and TGF-β in Aβ clearance by microglia cells. We used in vitro and in vivo mouse models that recapitulated acute and chronic aspects of microglial responses to Aβ peptides. We showed that crosstalk signaling between TGF-β and Smad2 was an important mediator of neuro-inflammation. These findings suggest that microglial TGF-β activity enhances the pathological progression to AD. As TGF-β displays broad regulatory effects on beneficial microglial functions, the activation of inflammatory crosstalk signaling between TGF-β and Smad2 may be a promising strategy to restore microglial functions, halt the progression of Aβ-driven pathology, and prevent AD development.

      • SCIESCOPUSKCI등재

        Neuroprotective Effects of a Butanol Fraction of Rosa hybrida Petals in a Middle Cerebral Artery Occlusion Model

        ( Go Eun Yang ),( Dong Sun Park ),( Sun Hee Lee ),( Dae Kwon Bae ),( Yun Hui Yang ),( Jang Been Kyung ),( Da Jeong Kim ),( Ehn Kyoung Choi ),( Jin Tae Hong ),( Heon Sang Jeong ),( Hee Jung Kim ),( Su 한국응용약물학회 2013 Biomolecules & Therapeutics(구 응용약물학회지) Vol.21 No.6

        The neuroprotective effects of a butanol fraction of white rose petal extract (WRPE-BF) were investigated in a middle cerebral artery occlusion (MCAO) model. Seven week-old male rats were orally administered WRPE-BF for 2 weeks and subjected to MCAO for 2 h, followed by reperfusion. Twenty-four h later, MCAO-induced behavioral dysfunctions were markedly improved in a dose-dependent manner by pretreatment with WRPE-BF. Moreover, higher dose of WRPE-BF not only decreased infarction area but also effectively reduced astrogliosis. The expression of inducible nitric oxide synthase, cyclooxygenase-2, and glial fi brillary acidic protein in MCAO model were markedly inhibited by WRPE-BF treatment. Notably, WRPE-BF decreased nitric oxide and malondialdehyde levels in the striatum and subventricular zone of stroke-challenged brains. These data suggested that WRPE-BF may exert its neuroprotective effects via anti-oxidative and anti-infl ammatory activities against ischemia-reperfusion brain injury and could be a good candidate as a therapeutic target for ischemic stroke.

      • Models of solar and lunar motions in the Chinese <i>Chongxiu-Daming</i> calendar

        Choi, Go-Eun,Lee, Ki-Won,Mihn, Byeong-Hee Elsevier 2018 ADVANCES IN SPACE RESEARCH Vol.62 No.11

        <P><B>Abstract</B></P> <P>The <I>Chongxiu-Damingli</I> (Revised Great Enlightenment Calendar) of the Jin dynasty (A.D. 1115–1234) was developed in 1171 and used until 1280 in China. It had also been used since the reign of King Sejong (A.D. 1418–1450) in Korea to supplement calculations of the eclipse times. In this study, we investigate solar and lunar motions in this calendar. Referring to the <I>Garyeong</I> (Example Supplement for the Calculations of Solar and Lunar Eclipses Occurred in 1447) preserved in Korea, we first investigate sunrise and sunset times by the <I>Chongxiu-Damingli</I> to estimate the observation sites of these times. We then analyze the calculation methods of solar and lunar motions and of the maximum eclipse time using the calendar. We find that a cubic equation was utilized to calculate sunrise and sunset times. Compared with the results of modern calculations, we also find that the sunrise and sunset times are more suitable at Kaifeng (capital of the Northern Song dynasty) than Beijing (capital of the Jin dynasty). This finding confirms the record of the <I>Jinshi</I> (History of the Jin Dynasty) that the <I>Chongxiu-Damingli</I> was made based on the calendar of the Northern Song dynasty. Regarding solar and lunar motions, we find that the mean absolute difference values between the <I>Chongxiu-Damingli</I> and modern calculations are ∼0.005 and ∼0.145 degrees, respectively. Lastly, we find that the difference in the time of maximum solar eclipse that occurred on 1447 September 10 in Seoul (capital of the Joseon dynasty) is approximately 1 min between the calendar and modern calculation. We believe that this study will contribute to understanding the <I>Chongxiu-Damingli</I> and comparing the accuracy with other Chinese calendars such as the <I>Shoushili</I>.</P>

      • KCI등재

        Screening of anti-nosemosis active compounds based on the structure-activity correlation

        Go Eun Byeol,Kim Ju-Gyeong,박희근,Kang Eun-Jin,Kim Hye-Kyung,Choi Yong Soo,Moon Jae-Hak 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

        Nosema ceranae infection in Apis mellifera acts as a virulent pathogenic factor of honeybee colony collapse. Fumagillin is the only effective antimicrobial agent currently used against the microsporidial parasite N. ceranae. However, the toxicity of fumagillin is a concern. Therefore, in the present study, the screening of potent alter natives for fumagillin was performed for a total of 21 compounds, including 15 phenolics and 6 monoterpenes, based on their structure–activity correlation. The anti-nosemosis activity of each compound was determined by the relative inhibition level against the expression of the N. ceranae virulence factor encoding the polar tube protein 3 (ptp3) mRNA of the ptp3 gene. Each compound was preliminarily evaluated at 100 and 200 µM treatment concentrations. Then, the activity of 12 compounds showing activity at 200 µM was additionally determined at 40 µM, a concentration generally used in apiaries. At this concentration, gallol (benzene-1,2,3-triol) and 3-pentylcatechol (PC) showed higher activities than fumagillin, and 4-pentylgallol (PG) exhibited activity at a similar level to fumagillin. All three compounds selected in this study were low-molecular-weight phenolics. Among them, PC and PG, chemically synthesized compounds, commonly possess a hydrocarbon side chain of the pentyl group (-C 5 H 11 ) in catechol and gallol, respectively. That is, the three treatment com pounds were selected as potential beneficial alternatives for fumagillin and were markedly different from fumagillin in terms of their chemical structure. These results may trigger further extensive research on the biological mechanism for the prevention of nosemosis.

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