한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

Carotenoid 색소의 급이가 양식 농어의 영양성분에 미치는 영향

강동수 여수대학교 1998 論文集 Vol.12 No.2

To investigate the effects on body components of sea bass by the supplemented carotenoids, fish were fed the diet each containing β-carotene, lutein ester, astaxanthin, astaxanthin monoester and astaxanthin diester for 8 weeks. Amino acids, nucleotides and their related compounds and fatty acids in muscle were analyzed. The contents of total amino acid were higher in astaxanthin monoester group than in other groups. The contens of total free acid were higher in astaxanthin monoester group than in other groups. In astaxanthin monoester group, the contents of taurine, threonine, proline, alanine, leucine, lysine, histidine and arginine were markedly higher than that of other groups, while the content of glutamic acid was lower. IMPlevel in astaxanthin monoester group was higher than that of other groups by the greatly increased during feeding experimental diet. In astaxanthin monoester group, saturated fatty acids were decreased during feeding experimental diet, while polyunsaturated fatty acids were increased. In summary, the level of amino acids, nucleotides and their related compounds and polyunsaturated fatty acids were higher in astaxanthin monoester group than in other groups. This suggested that the deposition of carotenoid was affected on these body components.

중합효소연쇄반응(Polymerase Chain Reaction)을 이용한 Fusobacterium nucleatum 및 Fusobacterium necrophorum의 동정에 관한 연구

강창우,박동성,윤수한 大韓齒科保存學會 1999 Restorative Dentistry & Endodontics Vol.24 No.1

유자 과피를 이용한 oleoresin 제조 및 항산화 활성

강동수,배태진 麗水大學校 産業基術硏究所 1999 産業基術硏究所 論文集 Vol.8 No.-

As a way of mass process for citron peel, the extracting conditions of oleoresin concentrated the original flavor and taste, such as kind of solvents, particle sizes of a sample, sample to solvent ratios, extracting temperatures and times, were studied. Among eight solvents used for oleoresin extraction from citron peel, the optimal solvent was ethyl alcohol. The most appropriate particle size of citron peel powder, extracting temperature and mixing ratio of citron peel to ethyl alcohol were 20 mesh, 40℃ and 1 to 8 (w/v), respectively. The basis of yield in oleoresin extraction, optimum extracting time ws about 2 hours. The yield of oleoresin under the above-mentioned conditions was 28.7%. When the induced heating-oxidize with soy bean oil and sesame oil added 0.8% of oleoresin citron peel, induction-time extension effect appeared antioxidant activity that was applicable for 83.6~86.0% about effection of addition of 0.02% BHA.

Tetrachloro-o-cresol의 製法에 關하여

呂壽東,姜淙熙 慶北工業專文大學 1966 論文集 Vol.3 No.-

Aromatic halogen derivatives have been shown a great deal of interest by various investigators as intermediates for other compounds, as insectcides, fungicides and dyeing properties. We also supposed that the chlorodeivatives of o-cresol would exhibits properties of fungicides, insecticides and dyeing. We introduced chlorine into o-cresol in the presence of a carrier, I2, at the temperature of 60 to 140℃ for 144 hours and obtained 142g alkali-soluble Compound and other polymer soluble in benzene. 1. We supposed that alkali-soluble compound which is main product would be tetrachloro-o-cresol through quantitative analysis, molecular weight and other properties. 2. A by-droduct solube in benzene is supposed to be an addition and more complicated polymer formed by intermolecular condensation between-CH2CI and-OH. 3. In this reaction, although a compound of monochloro and dichloro-cresol can be formed normally and easily, tri and tetrachloro-cresol is slow in reacation because of steric hindrance.

진양호 수질의 영양상태 평가에 관한 연구

강민수,김성우,이동근 경상대학교 환경보전연구소 1999 環境保全硏究所報 Vol.7 No.-

The purpose of this study was to assess trophic state of Chinyang Lake using monthly water quility data in 1998, and to suggest adequate protection method of water supply source. The results of water quality variations and trophic states were evaluated as follows; 1. Algae had rapidly grown from June, and this resulted in the increase of pH, Chlorophyll-a and COD. 2. The annual average ratio of COD by algal biomass to total COD was estimated to be 12% and had the highest value of 31.6% in June. 3. The ration of T-N/T-P was 53.7, and phosphorus became the liming factor for the eutrophication. 4. When considering T-P and Chlorophyll-a concentration, Chinyang Lake seems to be eutrophic state. 5. From the evaluation by TSI & LTSI methods, Chinyang Lake could become rapidly into eutrophic state.

제주마의 체형에 관한 연구

강민수,정창조,강태숙,박희석,김동후,정재준 제주대학교 농과대학 제주도축산문제연구소 1986 畜産論叢 Vol.1 No.1

자폐아동에서 FMR-1 유전자에 대한 분자유전학적 연구

강경미,곽동일,이민수 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: 자폐장애가 유전성이 있다고 제시하는 많은 쌍생아 및 가족연구와 유전자 연구에도 불구하고 이 질환의 유전방식과 관련 유전자는 현재까지 알려져 있지 않고, 이 장애는 임상적으로 이질적 장애이며 유전방식과 관련 유전자는 현재까지 알려져 있지 않고, 이 장애는 임상적 이질적 장애이며 유전적으로도 다인자 질환일 가능성이 높은 것으로 생각된다. 본 연구에서는 자폐장애와 FMR-1 유전자간의 연관성을 조사하고자 자폐장애 아동 총 66명을 대상으로 분자유전학적 검사를 시행하였다. 방 법: 연구대상군은 DSM-Ⅳ 진단기준으로 자폐장애가 해당하고 K-CARS 점수가 30점 이상인 아동들을 대상으로 하였다. Genomic DNA를 전혈에서 추출한후, 탐침 Xho/PstⅠ과 두 개의 제한효소(EcoR Ⅰ, Eag Ⅰ)를 사용하여 썼던 블롯팅을 시행하였다. 결 과: 연구대상 총 66명중 1명의 남아가 메칠화된 모자이크의 양상을 보이었고, 3명의 남아와 2명의 여아는 불완전 변이 양상을 보이었으나 완전 변이의 양상은 없었다. 결 론: 본 연구에서는 FMR-1 유전자가 자폐장애의 유전적 요인과 관련이 있다는 이전의 보고를 뒷받침할만한 명백한 결과를 얻지 못하였다. Objectives: To elucidate an association of the fragile X syndrome with autism, Southern blot analysis was performed in 66 autistic children aged from 2 years to 11 years. Methods: Subjects were 66 autistic children with of autistic disorder diagnosed by DSM-Ⅳ criteria and Childhood Autism Rating Scale-Korean version. Genomic DNA was extracted from peripheral blood and DNA was used to detect a FMR(Fragile Mental Retardation)-1 gene. Xho/PstI probes and two restriction enzymes(EcoRI, EagI)were used for Southern blot analysis. Results: There were one boy with a methylated mosaic pattern and 3 boys and 2 girls with an unmethylated premutation band. But there was no full mutation pattern. Conclusion: Although the possibility of the relationship between autistic disorder and FMR-1 gene has been suggested, the results from this study do not provide any definite association of FMR-1 gene with autism in autistic children.

저선량방사선이 햄스터의 협낭 기저세포 분열지수에 미치는 영향에 관한 연구

강병철,유동수 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.2

The purpose of the study was to investigate the effects of the low level irradiation on the mitotic index of the basal cells in the buccal pouch of hamsters(golden hamster: APG strain). After colchicine was administrated to the hamsters through the intraperitoneal. the low level radiation(5460mR) was exposed on the buccal pouch of hamsters. The mitotic index of the basal cells was estimated 2 hours after irradiation. The results were as follows: 1. The mean mitotic index of the control group was 4.32. 2. The mean mitotic index of the irradiated group was 2.46. 3. T-test of data in the irradiated group showed significant difference from the mitotic index in the control group. These results suggested the lowered mitotic index of the irradiated group resulted from the low level irradiation.