유리단 국소의치 장착 후 M.K.G.에 의한 하악운동 형태 및 속도의 변화

최현미,조주온,이상돈,송광엽,박찬운 全北大學校 齒醫學硏究所 1992 전북치대논문집 Vol.10 No.1

The purpose of this study is to evaluate the effects of distal extension partial denture on the mandibular movement patterns and velocity. The subjects are 10 patients who have unilateral or bilateral distal extension edentulous area in maxillary and/or mandibular arches. Their mandibular movement patterns and velocity had been measured by Mandibular Kinesiograph(M.K.G.-K6 diagnostic system, Myo-tronics Inc. Seattle. WA. U.S.A.) once just before the treatment and 8 times every week since the dentures were placed. The data have been analyzed statistically by means of ANOVA and Tukey test. The results have been obtained as follows : 1. The placement of the dentures has reduced the amount of vertical and antero-posterior displacement in the habitual mandibular movement significantly(p<0.01). 2. The maximum opening and closing velocity and the mean opening and closing velocity showed no significant change with the placement of the partial dentures(p>0.01). 3. The velocity trace of maximum opening-closing movement has been more regularized and well-coordinated, and the number of clicks decreased continuously after placement of the dentures and showed stable patterns since the 5th week(p<0.01). 4. The left deviation has been decreased significantly after the placement of the dentures and showed no significant change since the 4th week. The right deviation has also been reduced, but there was shown no difference after the 1st week(p<0.01). 5. The crossover pattern has been most frequently observed in the frontal plane and the sagittal plane. It has not been changed with the denture placement and stabilized uniformly.

포트폴리오에 나타난 자기반성의미 : 전문대학 유아교육실습생의 경험을 중심으로

최일선,조운주 이화여자대학교 교육과학연구소 2007 교육과학연구 Vol.38 No.2

The purpose of this study was to understand the meaning of self-reflection ina student teacher portfolio. For this purpose, the researchers performed theorientation about a student teacher portfolio to student teachers before studentteaching. And the student teachers made a student teacher portfolio during thefour weeks of student teaching. After student teaching, the researchersconducted self-evaluation and peer-evaluation questionnaire survey, and groupinterview of student teachers. The results of this study were as follows: first, student teachers hadopportunities to confirm their philosophy and knowledge level, and tried toconnect those with teaching practice in the process of making a student teacherportfolio. Second, student teachers experienced not only repeated reflection butalso shared reflection with peers through the student teacher portfolio. Third, thestudent teachers were convinced that a student teacher portfolio was theresources for future plans and recharging themselves. 본 연구의 목적은 유아교육실습생 포트폴리오에 나타난 자기반성의 의미를 이해하는 것이다. 이를 위해, 본 연구는 교육실습생들에게 교육실습 전에 포트폴리오 제작에 대한 사전교육을 실시하고, 교육실습기간 동안 포트폴리오를 제작하도록 하였다. 그리고 교육실습 후에는 자기 평가 및 동료 평가 질문지와 집단면담을 시행하는 순서로 이루어졌다. 본 연구의 결과는 다음과 같다. 첫째, 교육실습생들은 포트폴리오를 구성하는 과정에서 철학과 지식을 확인하는 기회를 가지며, 이를 교수 실제와 연계하려는 노력을 하였다. 둘째, 교육실습생포트폴리오는 교육실습생들로 하여금 반성을 반복적으로 하게 할 뿐 아니라 반성을 공유하는 기회를 제공하였다. 셋째, 교육실습생들은 포트폴리오를 미래 설계와 재충전의 자원으로 인식하였다.

TV 요리프로그램 진행자의 전문성 여부에 따른 구성내용의 질에 대한 시청자의 평가

김운주,최은희,김기현,김정숙,송현숙,정은옥 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.1

The purpose of this study was to develop the instrument to assess the TV cooking program contents and to indentify the difference of cooking program contents according to professionalism of MC. The evaluation sheet was composed of 5 sectors(sanitary practices, cooking process, information & proceeding, table setting & tasting, applicability) with all 32 questions, 5-Likert scale was used. College students majoring in food & nutrition were very interested in cooking program and 72.4% of respondents knew the cable TV Food channel. The major source of cooking information was TV(51.5%). The comparison of four TV cooking programs with professional MC(2 program) and amateur MC(2 program) was performed. Except applicability sector, the mean evaluation scores of professional cooking program were higher than amateur cooking program. In the amateur MC program, 'hand washing', 'use of hair restraints', 'separate use of cutting board', 'dish towel cleanliness', 'separation of service table', 'taking a chair in tasting', 'use of individual dish' items rated low rating score(<2.00) so more control was needed. The findings of this research suggest that cooking professional should be participate in developing TV cooking program as MC or staff.

충북지역 주부의 식품 위생 지식 및 행동 평가

김운주,최은희 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.5 No.-

The purpose of this study was to evaluate food safety knowledge and behaviors of housewives in Chungbuk province areas; and examine relationships between knowledge and behaviors. Results of this study showed respondents reported a satisfactory level of food safety knowledge(correct rate 78.5%). Respondents were most knowledgeable about 'food production & holding(80.5%)' and least konwledgeable about 'food poisoning(75.4%)'. The performance of food safety behaviors were not satisfactory(3.3). There were areas for improvement on 'I use different chopsticks to eating food, instead of using the cooking chopsticks'. 'I sanitize the cutting board daily.' 'I wash my hands with soap after cracking eggs.' 'I don't use hands to tasting sample foods'. 'I use different knives for meats and vegetables', 'I use different cutting boards by food'. 'I don't issue frozen item before cooking', 'I don't refreeze thawed food'. The Pearson correlations were calcuated between food safety knowledge and behaviors. A weak statisticallysignificant relationship was found between the two variables(r=0.285, p<0.01). The major source of food safety information was TV·radio (50.4%). Respondents' perception rate of HACCP symbol was 22.0%.

대학급식의 미생물적 품질보증을 위한 HACCP의 적용 : 참치샐러드 Tuna Salad

김운주,최은희,최현미,배주희,채현숙 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.1

The purpose of this study was to evaluate the microbiological quality, and to assure the safety of the food production process in the university foodservice facilities in accordance with the Hazard Analysis Critical Control Point(HACCP) concepts. The kitchen layout and time-temperature relationship, miciobiological quality(total plate count, coliform) were assessed to identify the critical point during each of the production phases. The results were as follows: 1) The kitchen layout had to be improved because contamination area was not separated from non-contamination area, and work table was in contact with washing sink. 2) Some employee did not follow personal hygiene standards(hand washing), and did not wear proper working uniforms(hair restraints). 3) The production time of tuna salad was 120 min, and environment temperature was 20.1~26.0℃. Improper receiving temperature, inproper holding practices(without cover at room temperature) were observed. 4) In the purchasing phase of the raw materials, the microbiological quality of green pepper was not at acceptable level based on the TPC(2.3×10^6CFU/g)and coliform(>14,000 MPN/g). During washing phase TPC was decreased about 3 log cycle. After cutting and holding phase the level of TPC and coliform were increased rapidly. At serving phase the microbiological quality of tuna salad were not at acceptable level(TPC 3.3×10^6 CFU/g, coliform 11,000 MPN/g) according to the standard set(TPC <10^5 CFU/g, coliform <100 MPN/g) by Sorberg et al. 5) For tuna salad, critical control points were purchasing and receiving of fresh vegetables, washing, cutting, holding, mixing and serving phase.

EFFECT OF EUGENOL AND CAPSAICIN ON THE VOLTAGE-DEPENDENT ION CHANNELS OF TRIGEMINAL AFFERENTS

김주연,박상진,최기운,최호영 대한치과보존학회 2000 Restorative Dentistry & Endodontics Vol.25 No.3

삼차신경절의 뉴런이 구강악안면영역에서의 촉각, 압각,온도각 및 통각 등 다양한 감각을 중추신경계로 전달하는 역할을 하는 것은 주지의 사실이다. 이러한 신경전달에 있어서 이온통로는 감각정보를 전달하는데 핵심적인 역할을 수행하며 특히 소디움 통로는 활동전위의 발생에 중요하다. 소디움 통로는 tetrodotoxin-sensitive(TTX-5) 및 tetrodotox-in-resistant(TTX-r) 통로로 나누어지는 데 이 중 TTX-r 통로에 발생되는 tetrodotoxin-resistant sodium cur-rent(TTX-r INa.)는 capsaicin에 민감한 일차구심신경세포에서 유해자극에 의해 통각신호를 발생시키고 전달하는데 중요하다. 또한 칼슘 통로는 시냅스 전토에 있어서 필수적인 역할을 수행하고 있다. 한편 치과영역에서 치수의 진정 목적으로 eugenol이 흔히 사용되고 있다. 그러나eugenol의 그 작용 기전에 대해서 현재까지 이온통로에 대한 상세한 결과가 없는 실정이며 최근의 보고에 의하면 eugenol이 capsaicin수용기를 통하여 감각신경에 대한 억제작용을 나타낸다고 한다. 따라서 본 실험은 eugenol과 capsaicin이 흰쥐의 삼차신경절의 TTX-r INa와 칼슘통로에 어떠한 영향을 미치는지를 알아보고 eugenol이 capsaicin 수용기를 통하여 작용하는지를 검증하고자 시행되었다 삼차신경절 뉴런은 100-150g의 흰쥐의 삼차신경절로부터 외과적으로 절제하여 통법의 화학적 및 기계적 처리를 통해 단일세포로 분리하였고 이를 Whole-cell patch clamp 방법을 이용하여 시행한 바 다음과 같은 결론을 얻었다. 1.1mM의 dugenol은 흰쥐 삼차신경절 뉴런의 TTX-r INa.와 HVA INa.를 억제하였다. 2.1㎛의 capsaicin은 흰쥐 삼차신경절 뉴런의 TTX-r INa 와 HVA INa 를 억제하였다 3.Capsazepine은 capsaicin의 HVA ICa 에 대한 억제작용을 차단하였다. 4.Capsazepine은 capsaicin의 HVA ICa .에 대한 억제작용을 차단하지 못하였다. 결론적 으로 eugenol과 capsaicin은 tetrodotoxin-resistant sodium current(TTX-r INa )와 high voltage-activated calcium current(HVA ICa )를 모두 억제하는 것으로 나타났으며 , 이러한 작용이 통각의 발생과 시냅스 전달과정을 차단하여 치수 진정 목적으로 많이 사용하는 eugenol의 작용기전으로 판단된다. 한편 capsaicin의 길항제인 capsazepine을 전처치하였을 때에도 eugenol의 HVA ICa 에 대한 억제효과는 변화가 없었다. 이와같은 결과로 보아 HVA ICa 에 관한한 eugenol은 capsaicin 수용기를 통하여 나타나지 않는 것으로 사료된다.

메치실린 내성 포도상구균에 대한 SK-302의 시험관내 및 생체내 효과

박윤선,김수기,신운섭,최선주,정종순,이종수 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

SK-302 is the active compound purified from culture filtrate of a streptomyces species (streptomyces sp. 302). The in vitro and in vivo antibacterial activities of SK-302 were evaluated against 6 clinically isolated MRSA strains and compared with the activities of vancomycin. SK-302 had node in virto antistaphylocoal activity stronger than that of vancomycin exhibiting MIC's, while vancomycin showed very weak 4 to 8fold lower than that of vancomycin. In SK-302 showed killing activity at the MIC, so SK-302 was superior to vancomycin. Furthermore, in acute systemic infections in mice, the ED_50s of SK-302 against infections by high-resistance MRSA were 30 to 40-feold less than that of vancomycin, therefore SK-302 showed potent in vive therapeutic efficacy against MRSA infection, These results suggest that SK-302 has excellent in virto in and in vivo activities against high-resistance MRSA.

간세포암종에 대한 간동맥 화학색전술 후 발생한 급성호흡곤란증후군

조윤원,이정미,최자윤,유동훈,차라리,오혜원,김홍준,민현주,김현진,정운태,이옥재,하창윤,이선영 이화여자대학교 의과학연구소 2013 EMJ (Ewha medical journal) Vol.36 No.1

Transcatheter arterial chemoembolization (TACE) has become an effective alternative treatment strategy for patients with inoperable hepatocellular carcinoma (HCC). Although TACE is relatively safe, acute respiratory distress syndrome associated with pulmonary lipiodol embolism is a rare and potentially fatal complication. We report a rare case of acute respiratory distress syndrome after TACE for inoperable HCC. A 75-year-old man, with huge HCC in right lobe, was treated by TACE for the first time. Seven hours after uneventful TACE procedure, he felt dyspneic and his oxygen saturation recorded by pulse oximetry (SpO2) fell to 80% despite of applying non-rebreathing mask. He underwent mechanical ventilation with a protective ventilatory strategy. We experienced a case of acute respiratory distress syndrome after TACE for HCC.

복귀돌연변이시험을 이용한 이온화에너지 처리 우유 및 아이스크림의 유전독성학적 평가

유지숙, 한선경, 신명수, 구본철, 최지현, 이주운, 조철훈, 함준상, 이완규 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.1

본문참고

Effect of Pitavastatin Compared with Atorvastatin andRosuvastatin on New-Onset Diabetes Mellitus in PatientsWith Acute Myocardial Infarction

Choi, Jah Yeon,Choi, Cheol Ung,Hwang, Soon-Young,Choi, Byoung Geol,Jang, Won Young,Kim, Do Young,Kim, Woohyeun,Park, Eun Jin,Lee, Sunki,Na, Jin Oh,Kim, Jin Won,Kim, Eung Ju,Rha, Seung-Woon,Park, Chang Elsevier 2018 The American Journal of Cardiology Vol.122 No.6

<P>Although statin use in patients with acute myocardial infarction (AMI) is mandatory, it has been suggested to be associated with new-onset diabetes mellitus (NODM). In real world practice, moderate-intensity statin therapy is more commonly used than high-intensity statin therapy. In this study, we investigated the impact of moderate-intensity pitavastatin (2 to 4 mg) compared with moderate-intensity atorvastatin (10 to 20 mg) and rosuvastatin (5 to 10 mg) on the development of NODM during a follow-up period of up to 3years. Between November 2011 and May 2015, 2001 patients with AMI who did not have diabetes mellitus were investigated. The cumulative incidence of NODM was evaluated in all groups. To adjust for potential confounders, multinomial propensity scores were used. Cox proportional hazard models were used to assess the hazard ratio of NODM in the atorvastatin and rosuvastatin groups compared with pitavastatin group. The cumulative incidence of NODM was significantly lower in pitavastatin group compared with the atorvastatin and rosuvastatin groups (3.0% vs 8.4% vs 10.4%, respectively; Log-rank p value = 0.001). After weighting the baseline characteristics of the 3 statin groups by multinomial propensity scores, atorvastatin (hazard ratio: 2.615, 95% confidence interval: 1.163 to 5.879) and rosuvastatin (hazard ratio: 3.906, 95% confidence interval: 1.756 to 8.688) were found to be associated with a higher incidence of NODM compared with pitavastatin therapy on multivariable analysis. Moderate-intensity pitavastatin therapy is associated with a lower incidence of NODM in patients with AMI andhas similar clinical outcomes to moderate-intensity atorvastatin and rosuvastatin therapy.</P>