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김태철,이규승,오범룡,민진우 忠南大學校 環境問題硏究所 1998 環境硏究 Vol.16 No.-
The effect of non-point source pollution in rural area has much influence on the stream water quality. It is difficult to improve the stream water quality, because of complex pollutant loads technically and because of treatment-cost of the deteriorated water economically. The best way to reduce the non-point source pollution is to check the water quality in the inlet of irrigation channel and control the water quality in the outlet of drainage channel. Stream water quality in the rural area is closely related with the fertilizers, pesticides, and livestock wastewater. Basically the rate of treatment and retention time were estimated for BOD, COD, SS, NH₄-N, T-N, NO₃-N, T-P, PO₄-P using materials such as gravel, crushed stone, useless tire, geotextiles, and concrete block, respectively and also using the combined materials. The rate of treatment for BOD, COD, SS is high, but that for NH₄-N, T-N, NO₃-N, T-P, PO₄-P is low. Optimal retention time in the natural contact channel was 90 minutes.
토끼에서 근육주사시 입자 크기에 따른 amoxicillin의 비교 약물동태학
박승춘,윤효인,오태광,장범수,배순이,조준형,정상희,이내경,김민규 충남대학교 수의과대학 동물의과학연구소 1998 動物醫科學硏究誌 Vol.6 No.-
To investigate the pharmacokinetic difference between the two amoxicillin (AMX) particles in rabbits after intramuscular injection (i.m.), both of AMX-S (particle size: 10 ㎍) and AMX-L (particle size: 100 ㎍) were injected into New Zealand White rabbits (1.2±0.3 ㎏) at a dose rate of 10 ㎎/㎏ of body weight. In this study, serum AMX concentrations were detected by microbiological assay with E. coli BE 1186 which shows high antibiotic sensitivity. After i.m. administration, AMX-S and AMX-L were best fitted as 1-compartment model with the absorption and elimination phase. The biological half-life (T_1/2, _k10) of AMX-S is 4.06±1.09 h and that of AMX-L 4.76±0.69 h. The serum maximal concentration time (T_max) of AMX-S and AMX-L were 0.88±0.17 h and 0.77±0.11 h, respectively. Maximal AMX concentration (C_max) (AMX-S: 5.71±0.62 ㎍/㎖, AMX-L: 5.04±0.25 ㎍/㎖) in serum showed a significant difference (p<0.05). In terms of bioequivalance, however, there was no difference between the two AMX's after i.m. injection in the basis of C_max and AUC.
Development of the Korean Version of the Gastrointestinal Quality of Life Index Questionnaire
( In Jun Yang ),( Heung-kwon Oh ),( Jeehye Lee ),( Jung Wook Suh ),( Hong-min Ahn ),( Hyeonjeong Park ),( Hyun Hee Sim ),( Yong Beom Cho ),( In Kyu Lee ),( Seungbum Ryoo ),( Dong-won Lee ),( Duck-woo 한국정맥경장영양학회 2022 한국정맥경장영양학회지 Vol.14 No.1
Purpose: To establish a standardized quality of life measurement that allows global cross-study comparisons, we translated the Gastrointestinal Quality of Life Index (GIQLI) into Korean and linguistically validated the Korean version of the GIQLI (K-GIQLI) in patients who underwent colorectal surgery. Materials and Methods: A cross-cultural adaptation of the original GIQLI was created based on the established guidelines. Based on participation in a cognitive interview, 20 patients with colorectal cancer were enrolled in the study. To ensure that the Korean version of the questionnaire was understood as intended, the time needed to complete the questionnaire was measured, and three additional items related to comprehension were added. Results: From May to July 2021, two translators, whose native language was Korean translated the GIQLI items into Korean, and a native English editor who had no knowledge of the original questionnaire translated the items back into English. In the cognitive interview, the median age of the patients was 61.8 (range: 44~82) years, and the median time required to complete the questionnaire was 6.5 (range: 5~10) min. For the language and cultural adaptation process, the participants’ comprehension of the questionnaire was measured on a scale of 1~5, with a mean score of 4 (range: 3~4). Conclusion: The K-GIQLI was developed and did not exhibit a significant difference from the original English version in terms of social, linguistic, and cultural differences between the Western world and Republic of Korea.
만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정
오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3
Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.
Min, Beom Kyu,Kim, Gieun,Roh, Hwa Jung,Seo, Da Young,Kim, Jae Nyoung Elsevier 2018 Tetrahedron letters: the international organ for t Vol.59 No.17
<P><B>Abstract</B></P> <P>Various spirooxindoles bearing 2,3-(or 2,5-)dihydrothiophene-2-thione moiety have been synthesized via [3+2] annulation reaction of carbon disulfide and the nitrogen ylides derived from Morita-Baylis-Hillman carbonates of isatins. 2,3-Dihydro- and 2,5-dihydrothiophene-2-thione moieties were formed selectively depending on steric hindrance around the nitrogen ylides.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Synthesis of spirooxindoles bearing dihydrothiophene-2-thione. </LI> <LI> Control of regiochemistry by tertiary amine catalysts. </LI> <LI> Regioselective [3+2] annulation of <I>N</I>-ylides of MBH carbonates and carbon disulfide. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Effect of the volumetric dimensions of a complete arch on the accuracy of scanners
Kim, Min-Kyu,Son, KeunBaDa,Yu, Beom-Young,Lee, Kyu-Bok The Korean Academy of Prosthodonitics 2020 The Journal of Advanced Prosthodontics Vol.12 No.6
PURPOSE. The present study aimed to evaluate the accuracy of a desktop scanner and intraoral scanners based on the volumetric dimensions of a complete arch. MATERIALS AND METHODS. Seven reference models were fabricated based on the volumetric dimensions of complete arch (70%, 80%, 90%, 100%, 110%, 120%, and 130%). The reference models were digitized using an industrial scanner (Solutionix C500; MEDIT) for the fabrication of a computer-aided design (CAD) reference model (CRM). The reference models were digitized using three intraoral scanners (CS3600, Trios3, and i500) and one desktop scanner (E1) to fabricate a CAD test model (CTM). CRM and CTM were then superimposed using inspection software, and 3D analysis was conducted. For statistical analysis, one-way analysis of variance was used to verify the difference in accuracy based on the volumetric dimensions of the complete arch and the accuracy based on the scanners, and the differences among the groups were analyzed using the Tukey HSD test as a post-hoc test (α=.05). RESULTS. The three different scanners showed a significant difference in accuracy based on the volumetric dimensions of the complete arch (P<.05), but the desktop scanner did not show a significant difference in accuracy based on the volumetric dimensions of the complete arch (P=.808). CONCLUSION. The accuracy of the intraoral scanners was dependent on the volumetric dimensions of the complete arch, but the volumetric dimensions of the complete arch had no effect on the accuracy of the desktop scanner. Additionally, depending on the type of intraoral scanners, the accuracy differed according to the volumetric dimensions of the complete arch.