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김병조,Qasim,Syed R,Verma,Rameshwar D 한국화학공학회 1971 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.9 No.3
The use of microstrainers in the water and wastewater engineering field is expected to increase in the future. Currently employed design methods for microstrainers are based on Boucher's straining law which assumes a constant rate of flow. The assumption of a constant pressure head is more appropriate than that of a constant flow rate. Governing equations describing the hydraulics of filtration through microstrainers based on these two assumptions are analyzed and compared.
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Coacervation-상분리법으로 만든 Ethyl Cellulose 마이크로캅셀의 Glibenclamide 방출특성 및 수용성 첨가제의 영향
김병조,장정수,이문주,김상헌,최영욱 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-
Glibenclamide (GBC) is a well-known antidiabetic agent, which stimulates the secretion of endogenous insulin by pancreatic βcells. However, administration of GBC at a high dose can occasionally induced the fatal hypoglycemia, especially in the patients with impaired liver function. Therefore, in order to develop an oral sustained-release preparation which reduces the side effect, microcapsulation of GBC has been carried out in this experiment. Microcapsules of GBC were prepared by coacervation-phase separation method with ethylcellulose as a wall-forming material in cyclohexane, using polyisobutylene as a coacervation-inducing agent. Different amounts of hydrophilic additives. L-arginine(ARG) and polyethylene glycol 4000 (PEG), were added to the microcapsule wall, in order to alter the porosity of the wall and hence to enhance the release of the core material. The microcapsules prepared were examined for physical properties by scanning electron microscopy (SEM) and particle size analysis. The release of the poorly water-soluble GBC was found to be very slow from the microcapsules and strongly dependent on the core to wall ratio of the microcapsules, but it was accelerated considerably with increasing amount of PEG or ARG. In general, on the basis of dissolution kinetics, GBC releases from microcapsules were followed apparent first-order kinetics, while the dissolution data of GBC powder conformed to Hixon-Crowell's cube root law. Therefore, in conclusion, it might be possible to design the sustained-release formulation by the combination of both GBC powder and microcapsules of different core wall ratio with or without hydrophilic additives.
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Wearable device를 이용한 선원의 수면 시간과 효율성에 관한 기초연구
김병조,이정훈,이수경,권해연 한국항해항만학회 2018 한국항해항만학회 학술대회논문집 Vol.2018 No.추계
선원은 충분한 수면으로 신체적 정신적 피로를 완전히 회복하지 못한 수면부족 상태에서 재승선하여 장기간 항해와 흔들리는 선박 위에서 반복적인 작업 활동을 수행하므로 누적 피로도와 스트레스가 증가하는 악순환을 초래하며 이로 인한 해양 인적사고가 발생할 수있다. 따라서 사람의 주관적인 판단에 의한 자기평가방법으로 기입하는 설문지 분석이 아닌 선박에 승선하는 동안에 Wearable device를 착용한 상태에서 과학적이고 객관적인 선원의 수면 시간과 효율성을 분석하였다.
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자율신경 기능평가를 통해 측정한 선원의 누적피로도 및 스트레스와 조사연구 사이의 관련성
김병조,권해연,이수경,채병근,이정훈,권영태,박용선 대한통합의학회 2018 대한통합의학회지 Vol.6 No.4
Purpose : The purpose of this study has been performed to find the relationship between seafarers' cumulative fatigue and stress measured by evaluating autonomic nervous functions and the results of surveys conducted using questionnaires. Methods : The subjects were seafarers working on various ships (home trade ships) of South Korea, who were healthy adults without any diseases, as confirmed through preliminary surveys were recruited through simple random sampling. A device that measures autonomic nervous functions by analyzing heart rate variability(Omnifit Mind care, Korea), which is also used often in clinical diagnoses and studies at universities, university hospitals, and general hospitals was used to measure the seafarers' cumulative fatigue and stress. Pearson's correlation analyses were also conducted to test the relationship between cumulative fatigue and stress measured by evaluating autonomic nervous functions and the results of surveys conducted with questionnaires. Result : There was no correlation between mean cumulative fatigue measured for each ship type and seafarers position through autonomic nervous functions evaluation and fatigue severity scale(FSS). There also was no correlation between the mean levels of stress measured for each ship type and seafarers position through autonomic nervous functions evaluation and survey scores of Korean occupational stress scale(KOSS). Conclusion : Therefore, in order to prevent man-made accidents in the sea among seafarers working with irregular port entry/departure schedules and under environments involving continued vibration, noises, and shaking, it is necessary to analyzed cumulative fatigue and stress scientifically and objectively, such as through autonomic nervous functions evaluation rather than through surveys.
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김병조,김성환,박용원,이기재 인제대학교 1993 仁濟醫學 Vol.14 No.4
저자들은 뇌혈관조영술로 확진된 Moyamoya병 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Moyamoya disease is a chronic, progressive vascular disorder, characterized by stenosis or occlusion of the supraclinoid portion of the internal carotid artery with extension Into the proximal portion of the anterior and middle cerebral arteries. There is an associated finding of collateral vascular networks(Moyamoya vessels, that is "something hazy, like a puff of smoke" appearance) in the region of the basal ganglia. We experienced a case of Moyamoya disease in a 11 year old girl who had frequent episodic transient weakness of the left lower extremity and headache, which was confirmed by four vessel angiogram.
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