Prevalence of Women with Dense Breasts in Korea: Results from a Nationwide Cross-sectional Study

조혜미,이은혜,고경란,강봉주,차주희,이안,정혜경,전재관 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4

Purpose Women with dense breast are known to be at high risk for breast cancer, but their prevalence and number of Korean women are unknown. The current study was to investigate the distribution of mammographic breast density by age of women undergoing screening mammography, and to estimate the prevalence of Korean women with dense breasts, quantitatively. Materials and Methods For obtaining a nationwide representative sample, 6,481 mammograms were collected from 86 screening units participated in the National Cancer Screening Program for breast cancer. Based on the American College of Radiology Breast Imaging Reporting and Data System classification, breast density was evaluated by six breast radiologists, qualitatively. We applied these breast density distributions to age-specific counts of the Korean women population derived to mid-year 2017 to estimate the number of Korean women with dense breasts. Results Overall, 54.4% (95% confidence interval [CI], 52.9% to 55.8%) of women 40 to 69 years of age had heterogeneously or extremely dense breasts, and this proportion was inversely associated with age. Based on the age distribution of Korean women, we estimated that 6,083,000 women (95% CI, 5,919,600 to 6,245,600) age 40-69 years in Korean have dense breasts. Women aged 40-49 years (n=3,450,000) accounted for 56.7% of this group. Conclusion More than half of Korean women aged 40 and over have dense breasts. To prevent breast cancer effectively and efficiently, it is necessary to develop a new personalized prevention strategy considering her status of breast density.

Fabrication of Graphene-Quantum Dot hybrid films for photodetectors

조혜미,양승보,김대우,윤상천,정희태 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.1

일부 공단지역 주민의 혈 중 납 농도에 관한 연구

조혜미,조태진,양원호,이종화,손부순,Jou, Hye-Mee,Cho, Tae-Jin,Yang, Won-Ho,Lee, Jong-Wha,Son, Bu-Soon 한국환경보건학회 2009 한국환경보건학회지 Vol.35 No.2

This study analyzed the concentration of the lead in blood (n=774) from May, 2007 to Oct 2007. The subject was residents in G, Y, H industrial area, Jeollanam-do, in which exposure to the lead is expected due to the adjacency of the industrial complex. As to the lead concentration in the blood of the residents in the whole exposed region and the comparing region, $2.81{\mu}g/dl$ in the exposed region group, and $2.86{\mu}g/dl$ in the comparing region group Respectively, which indicates that the concentration of the comparing group was higher than that of the exposed group. The geometric mean concentration of lead in blood was $3.26{\mu}g/dl$ as to men, and $2.46{\mu}g/dl$ as to women, which indicates that the concentration of men is higher than that of women (p<0.01). The lead concentration for each age group increased in proportion to age except those under 10 for some substances (p<0.01). As to geometric mean concentration in blood according to the smoking history of the subject, the concentration of the smoking group and the non-smoking group was $3.57{\mu}g/dl$ and $2.66{\mu}g/dl$ respectively, which indicates the former is higher than the latter (p<0.01). To clarify the factors affecting the heavy metal concentration in blood among the subjects, the multiple regression analysis was conducted. As a result, it turned out that as to lead content in blood, gender, age, smoking all affect the lead concentration of the subjects ($R^2$=23.3%).

소자강기탕을 투여한 천식환자의 치험 1례

조혜미,길봉훈,이은창,윤혜수,김동원,한다영,정다해,이정은,Jo, Hye-mi,Kil, Bong-hun,Lee, Eun-chang,Youn, Hye-soo,Kim, Dong-won,Han, Da-young,Jung, Da-hae,Lee, Jung-eun 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5

Objectives: This study aimed to describe the effects of traditional Korean medical treatment on a patient with asthma. Methods: The patient (female, 88) was treated with herbal medicine (Sojaganggi-tang), acupuncture, and moxibustion. The effects of these treatments were evaluated using the Modified Borg Scale (MBS) and Quality of Life Questionnaire for Adult Korean Asthmatics (QLQAKA). Results: Following treatment, the MBS score decreased from 7 to 4, and the QLQAKA score increased from 45 to 57. Conclusion: The results suggest that traditional Korean medicine can effectively treat patients with asthma.

X-선 형광분석법을 이용한 Biphasic calcium phosphate의 Ca/P 정량 분석법 연구

조혜미,양범진,이병현,Aditya Sharma,Mayora Varshney,원성옥 한국분석과학회 2016 학술대회논문집 Vol.2016 No.11

급성 요추 압박골절 후 발생한 폐렴과 동반된 연하곤란 및 식욕부진에 대한 치험 1례

조혜미,이은창,윤혜수,박충현,한다영,정다해,이정은 대한한방내과학회 2022 大韓韓方內科學會誌 Vol.43 No.2

Objective: The aim of this study is to describe the effects of traditional Korean medicine on a patient with dysphagia and anorexia following an acute lumbar compression fracture. Methods: The patient was treated with acupuncture and herbal medicine (Bojungikgi-tang and Insamyangyoung-tang), and the effects of the treatment were evaluated by monitoring oral feeding and using the Modified Barium Swallow (MBS) test. Results: After treatment, the amount of oral feeding more than doubled and the MBS was also improved. Conclusion: The results suggest that traditional Korean medicine may be effective for treating dysphagia and anorexia after an acute lumbar compression fracture.

Fabrication of Graphene-Quantum dot photosensitive hybrid films

조혜미,양승보,김대우,정희태 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.2

Physical Exfoliation of Graphene Sheets by Nanoparticulate Polypyrrole for Capacitive Electrode Materials

조혜미,윤현석 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2

Nanoparticulate polypyrrole (NPPy) was successfully invited as a guest species into graphene layers using physical approach, which resulted in the formation of a unique three-dimensional hybrid nanoarchitecture. The electrochemical properties of graphene/NPPy hybrids were examined with considering the size and content of the NPPy as significant variables. The NPPy was intercalated into graphene layers to build 3D structures, which enhanced accessible surface area and allowed fast ion diffusion in/out of the structure. The packing density of the alternately stacked nanohybrid structures depended on the NPPy content, importantly which affected the volumetric capacitance. The nanohybrids exhibited excellent performance stability in charge/discharge cycling due to their structural synergistic effects. Finally, the all-solid state capacitor cell based on the nanohybrid electrodes exhibited excellent mechanical flexibility and high energy density.

통계적 3차 모멘트 기반의 목적함수를 이용한 NSRP 모형의 극치강우 재현능력 평가

조혜미,김용탁,유재웅,권현한 한국수자원학회 2022 한국수자원학회논문집 Vol.55 No.7

It is recommended to use long-term hydrometeorological data for more than the service life of the hydraulic structures and water resource planning. For the purpose of expanding rainfall data, stochastic simulation models, such as Modified Bartlett-Lewis Rectangular Pulse (BLRP) and Neyman-Scott Rectangular Pulse (NSRP) models, have been widely used. The optimal parameters of the model can be estimated by repeatedly comparing the statistical moments defined through a combination of parameters of the probability distribution in the optimization context. However, parameter estimation using relatively small observed rainfall statistics corresponds to an ill-posed problem, leading to an increase in uncertainty in the parameter estimation process. In addition, as shown in previous studies, extreme values are underestimated because objective functions are typically defined by the first and second statistical moments (i.e., mean and variance). In this regard, this study estimated the parameters of the NSRP model using the objective function with the third moment and compared it with the existing approach based on the first and second moments in terms of estimation of extreme rainfall. It was found that the first and second moments did not show a significant difference depending on whether or not the skewness was considered in the objective function. However, the proposed model showed significantly improved performance in terms of estimation of design rainfalls. 수공구조물 설계 및 수자원 계획에서는 목표연도 이상의 수문기상자료를 활용하는 것이 추천된다. 강우 자료의 확장을 위해 추계학적 강수 모의 모형을 활용하는데, Bartlett-Lewis Rectangular Pulse Modified Model (BLRPM)과 Neyman-Scott Rectangular Pulse Model(NSRPM)이 대표적이다. 이 모형들은 확률분포의 매개변수 조합을 통해 추정되는 통계적 모멘트와 관측값의 통계적 모멘트를 반복 비교하여 최적 매개변수를 추정한다. 그러나 상대적으로 적은 관측값을 이용하여 매개변수를 추정하는 것은 부적절하게 정의된 문제(ill-posed problem)에 해당하며, 최적화 과정에서 매개변수 추정이 어려울 뿐만 아니라, 매개변수의 변동성도 매우 크다. 또한, 일부 연구에서 드러나듯이, 모형 매개변수 추정과정에서 다양한 목적함수를 활용해도 2차 모멘트에 국한되어 있어, 극치 강수량 재현에는 한계가 있다. 따라서 본 연구는 3차 모멘트를 포함한 목적함수를 활용하여 NSRPM 매개변수를 추정하고, 기존 2차 모멘트를 이용한 매개변수 접근방법과 극치강수량 재현 측면에서 비교를 수행하였다. 그 결과, 목적함수의 왜곡도 포함 여부에 따라 1, 2차 모멘트는 큰 차이를 나타내지 않았지만, 극치강우 재현 측면에서는 왜곡도를 포함한 경우가 포함하지 않은 경우보다 개선된 결과를 나타냈다.

2009 및 2015 개정 교육과정의 고등학교 화학에 대한 비교 분석

조혜미,최기영,장낙한 공주대학교 과학교육연구소 2016 과학교육연구 Vol.46 No.1

This study was compared and analyzed for 2009 revision curriculum and 2015 revision curriculum with emphasis on chemistry subjects. The 2015 Revised Curriculum was a student-centered curriculum designed to develop fosters students' dreams and talent and balanced basic knowledge. It also tried to improve the problems of the 2009 revised curriculum. the education paradigm was defined as 'happiness education' which enjoys learning more than teaching. It was expand the 'Scientific research experiments' and improve the contents of 'goal' and 'teaching-learning method and evaluation', 'achievement standard' statements way. The 2015 revised curriculum reflects 'Scientific core competence' in a multifaceted way to cultivate core competencies needed for future society. In addition, the 2015 revision curriculum explains chemistry in an integrated way with other subjects, and emphasized various "Connectivity". It emphasized the appropriateness of learning contents. The 2015 revised curriculum aims to realize the appropriate level of learning difficulty and appropriate the amount of learning. by appropriately moving, transforming and deleting units and content elements and achievement standard.