활동적 비디오 게임을 활용한 신체활동이 고지방식이 후 혈관기능에 미치는 영향

윤은선,박수현,이용희,안의수,제세영 한국운동생리학회(구 한국운동과학회) 2013 운동과학 Vol.22 No.1

본 연구의 목적은 고지방 식이 섭취 후 활동적 비디오 게임을 이용한 신체활동이 혈관기능에 미치는 영향에 대해 알아보는 데 있다. 피험자는 정상체중의 건강한 성인 16명(남자 9명, 여자 7명, 나이 24±4세, 체질량지수 22.4±2.1 ㎏/㎡)을 대상으로 하였으며 모든 피험자가 신체활동 처치와 통제 처치에 모두 참여하는 cross-over design으로 설계하였다. 고지방식이는 총 1,257 kcal의 햄버거를 섭취하였다. 신체활동은 고지방 식이 섭취 후 30분에 50분간 활동적 비디오 게임(50분)을 실시하였다. 종속변인으로 혈중지질(총 콜레스테롤, 중성지방, 저밀도 지단백 콜레스테롤, 고밀도 지단백 콜레스테롤), 혈압, 혈관기능(상완동맥 혈류 의존성 혈관 이완능, 경동맥-대퇴동맥 맥파전파속도)을 측정하였으며, 측정시기는 고지방 식이 전, 고지방 식이 후 3시간, 고지방 식이 후 5시간으로 하였다. 연구 결과, 일시적 고지방식이는 활동적 비디오 게임 처치와 통제처치 모두 혈중 중성지방 농도를 유의하게 증가시켰으나(시기 효과, p=0.001) 두 처치 간 유의한 차이는 없었다. 혈관내피세포 기능은 고지방 식이 후 3시간에 통제처치에서는 감소된 반면(사전:9.32±2.86 %, 식후 3시간:8.13±3.56 %), 활동적 비디오 게임 처치에서는 혈관내피세포 기능이 개선되는 경향을 보였으나 통계적으로 유의한 차이는 나타나지 않았다(사전:8.74±3.13 %, 식후 3시간:9.21±3.40 %). 경동맥-대퇴동맥 맥파전파속도는 고지방 식이 후 변화를 보이지 않았으며 처치 간 차이 또한 나타나지 않았다. 본 연구의 결과를 종합해 보면, 고지방 식이 후 활동적 비디오 게임의 실시는 혈중 중성지방 증가를 유의하게 감소시키지 못하였으며, 고지방식이로 인한 혈관내피세포 기능 및 동맥경직도 변화를 개선시키지 못하였다. 따라서 건강한 성인에게 활동적 비디오 게임은 고지방 식이에 따른 혈관 기능 변화에 있어 운동의 보호적 효과를 얻기에 운동강도 및 운동량이 부족한 것으로 사료된다. A high fat meal transiently decreases vascular function, while acute aerobic exercise improves vascular function. Active video games are now highly popular and play a role in promoting physical activity. Although studies suggest that acute aerobic exercise attenuates high fat meal induced vascular dysfunction, but it is not clear whether an active video game could attenuate vascular dysfunction after a high fat meal. We tested the hypothesis that an active video game would partial l y prevent the unfavorable effect of vascular function by high fat meal in young adults. Using a randomized cross over design, sixteen healthy young subjects (male 9, female 7;age 24±4 yrs, BMI 22.4±2.1 ㎏/㎡) were assigned to both an active video game(AVG:50 minutes) and a seated rest(CON) after a high fat meal. Lipid profiles, blood pressure, and vascular function measured at baseline, 3 and 5 hours after a high fat meal. Vascular function was measured by endothelial function(brachial artery flow mediated dilation;FMD) and arterial stiffness(carotid-femoral pulse wave velocity;C-F PWV). Blood triglyceride levels were significantly increased in two treatment conditions after a high fat meal and did not significantly different between two groups(AVG:74.06±43.36, 160.63±106.20, 126.81±91.41 mg/dl;CON:70.06±38.67, 168.38±85.89, 128.75±87.26 mg/dl, p=0.878). FMD was decreased in the CON (9.32±2.86 to 8.13±3.56 %), but increased in the AVG (8.74±3.13 % to 9.21±3.40 %) at 3 hr after a high fat meal. However, there was no significantly different between two groups (p=0.189). C-F PWV was similarly decreased in two treatment conditions after a high fat meal and did not significantly different between two groups (AVG:6.39±1.12, 6.08±0.94, 6.38±1.07 m/s;CON:6.34±0.85, 6.19±0.89, 6.28±1.01 m/s, p=0.483). These findings show that a high fat meal caused a temporary decrease in endothelial function, but these decreases were not significantly attenuated in the group with active video game compare to the group with seated rest. Therefore, active video game may not have a cardioprotective effect in young healthy adults exposed to acute high fat meal.

Polystyrene 중공 미세구에 대한 연구

윤은선,김민경,박용성,우제완,황영애 한국공업화학회 2001 한국공업화학회 연구논문 초록집 Vol.2001 No.1

N/A

한국 성인의 사회 심리적 스트레스와 운동 미참여의 관련성 : 한국인 유전체 역학 조사사업 자료를 기반으로

윤은선,박수현,박세정 한국운동생리학회 2019 운동과학 Vol.28 No.4

PURPOSE: Psychological factors have been identified as an important factor underlying physical activity behavior in adults. However, the extent to which these psychological factors impact physical activity behavior remains poorly understood. The aim of the study was to examine the association between psychological stress and physical inactivity in subsets of data from the Korean Genome and Epidemiology Study (KoGES). METHODS: 69,219 participants (24,025 men) aged 40-69 were drawn from urban and rural community based cohort studies, which are subprojects of KoGES. We analyzed the association between psychological stress and physical inactivity using logistic regression. Cox’s proportional hazard regression analysis was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of exercise behavior changes according to psychological stress level changes. RESULTS: Compared to the healthy stress group, the likelihood of physical inactivity was increased in high-risk stress group (men OR=1.88, 95% CI 1.63-2.17, p<0.001, women OR=2.24 95% CI, 2.04-2.47, p<0.001). During the mean follow-up period of 4.6 years, compared to the sustained healthy stress, the group with increased stress level was at a higher risk of remaining physical inactive (men HR=2.16, 95% CI 1.24-3.69, p<0.001, women HR=1.54, 95% CI 1.12-4.06, p<0.001), and the risk becoming physical inactive (men HR=2.33, 95% CI 1.33-4.09, p=0.003, women HR=2.13, 95% CI 1.12-4.06, p=0.021). CONCLUSIONS: These results suggest that the psychological stress could be barrier of exercise participation. Management of psychological stress should be considered in the strategy for promoting exercise participation in the community.

젊은 성인에서 허혈성 전처치가 최대운동수행능력에 미치는 영향

윤은선,제세영 대한스포츠의학회 2018 대한스포츠의학회지 Vol.36 No.2

Purpose: Remote ischemic preconditioning (RIPC), induced by repeated bouts of ischemia followed by reperfusion of the arm or leg is a noninvasive strategy to protect a target organ against oxidative stress and injury caused by ischemia and reperfusion. Interestingly, recent evidence suggests that RIPC may also improve exercise performance by increasing maximal oxygen consumption, but such finding remain equivocal. As such, the purpose of the study was to examine the effect of RIPC on exercise performance in healthy individuals. Methods: In a randomized cross-over design, 17 healthy male participants (age, 23±3 years) were exposed to either a sham control (six cycles of 5 minutes bilateral thigh cuff occlusion at 20 mm Hg) or RIPC (six cycles of 5 minutes bilateral thigh cuff occlusion at 180 mm Hg) an hour before a maximal exercise test. We measured maximal oxygen consumption, power output, heat rate, blood pressure, and blood lactate as exercise performance parameters during a maximal exercise test performed on an upright bicycle. Results: Compared with the sham control, RIPC improved maximal oxygen consumption (7.4%, p=0.025) and maximal power output (11.5%, p=0.010), whereas other exercise performance parameters remained unchanged with RIPC (p>0.05). Conclusion: Taken together, the improvements in maximal oxygen consumption and maximal power output induced by RIPC may suggest that RIPC should be considered as a method for improving exercise performance.

동물원(動物園)의 야생동물(野生動物) 분변(糞便)에서 분리(分離)한 살모넬라균의 생물형(生物型), 혈청형(血淸型) 및 약제내성(藥劑耐性)

윤은선,박석기,오영희,김태종,Youn, En-sun,Park, Seog-gee,Oh, Young-hee,Kim, Tae-jong 대한수의학회 1994 大韓獸醫學會誌 Vol.34 No.2

Feces samples, obtained from zoo animals around Seoul, were examined for the isolation of Salmonella species, bioserotype and drug resistance for the prevention and treatment of salmonellosis, Salmonella spp were isolated 19(4.7%) from 408 samples of zoo animals. The subspecies in 19 Salmonella were all subspecies 1. The serological identification of Salmonella isolated were 31.6% in Sal typhimurium, 26.3% in Sal hadar, 21.1% in Sal muenchen, 15.8% in Sal enteritidis and 5.3% in Sal ayinde. The antibiotic resistance of Salmonella isolated were 13(68.4%) strains. The multiple resistant patterns of antibiotics in Salmonella were 2 drugs- and 3 drugs-resistance 30.8% respectively. The transferred rate of resistance to recipients(E coli ML 1410 $NA^r$) in Salmonella was 38.5%.

다중 polymer 중공 미세구의 제조에 관한 연구

윤은선,유종춘,박용성,우제완,최성수,황영애 한국공업화학회 2001 한국공업화학회 연구논문 초록집 Vol.2001 No.-

Hydrocarbon polymer microballon은 연료 저장용기로써 실리카 중공 미세구에 비하여 몇 가지 장점을 가지고 있다. 즉, Polymer shell을 사용하였을 경우에는 보다 효율적으로 연료를 폭발시키고, 과열 발산을 줄일 수 있으며 상대적으로 X-ray를 잘 투과시키지만 속이 비어 있거나 다른 종류의 고분자 들에 의한 다중 고분자 층을 형성할 때에는 빛을 산란시켜는 현상을 보인다. 따라서 polymer shell 형태의 중공 미세구들에 대한 안료나 연료 저장 용기 등의 분야에서의 응용 연구가 활발히 진행 중에 있다. 본 연구에서는 polyvinylalcohol 수용액올 polystyrene 용액 속에 넣어 일차적으로 W₁/O emulsion을 만들고 이를 gelatin 수용액에 첨가한 W₁/O/W₂ emulsion 상에서 용매를 증발시키면 두개의 고분자 shell을 갖는 미세구를 제조할 수 있음을 확인하였다. 또한 고분자 중공 미세구의 크기는 W₁/O emulsion 생성시의 교반 속도에 영향을 가장 많이 받으며 교반 속도가 증가함에 따라 입자의 크기는 작아지는 경향을 보이며 입자의 생성에 필요한 시간은 감소함을 나타낸다. 하지만 W₁/O/W₂ emulsion 생성시의 교반 속도와 시간에는 거의 영향을 받지 않음을 확인하였다.

수입과일의 농약잔류 실태

윤은선,이명숙,정소영,김경식,채영주,박석기 한국농약과학회 2006 한국농약과학회 학술발표대회 논문집 Vol.- No.-

한국 성인에서 상대악력과 제2형 당뇨병 발생률과의 연관성: 한국인 유전체 역학 조사사업 자료를 기반으로

윤은선,박수현 한국운동생리학회 2020 운동과학 Vol.29 No.4

PURPOSE: We investigated whether relative handgrip strength (RHS) and change in handgrip strength predicted Type 2 DM incidence in middle-aged and older adults. METHODS: Total of 29,098 participants (8,609 men and 20,489 women) aged 40-69 who were free of diabetes at the baseline examination drawn from the Korean Genome and Epidemiology Study-Urban Health Examinees cohort (KoGES-HEXA), a large prospective population-based study. RHS was assessed with a dynamometer and divided by body mass index. Diabetes was defined as selfreported physician-diagnosed diabetes, use of anti-diabetic medications or measured fasting glucose ≥126 mg/dl, or glycated hemoglobin (HbA1C) ≥6.5%. Cox proportional hazard regression analysis was used to estimate the hazard ratio (HRs) and 95% confidence intervals (CIs) of Diabetes incidences according to baseline RHS levels and RHS changes. RESULTS: During a mean follow-up period of 4 years (49.8±13.3 month), 1,167 (4.0%) participants developed diabetes. Compared with the high RHS group, higher risk of diabetes incidence was observed in low RHS group (men HR=1.28, 95% CI 1.06-1.55, women HR=1.32, 95% CI 1.12-1.54) after adjusted for age, triglyceride, cigarette smoking, alcohol consumption, marriage, income, education hypertension, family history of diabetes, fasting glucose, regular exercise. In addition, compared with the sustained high RHS group, sustained low RHS group showed an increased risk of diabetes incidence (men HR=1.60, 95% CI 1.28-2.00, women HR=1.85, 95% CI 1.52-2.24) after adjustment. However, the risk was not statistically significant in increased RHS group (men HR=0.98, 95% CI 0.73-1.31, women HR=1.11, 95% CI 0.85-1.43). CONCLUSIONS: The present findings indicate that RHS is independently associated with the risk of incident diabetes in middle and older adults. RHS measurement may be useful to identify individuals at increased risk for diabetes incidence. Maintaining a high level of RHS is important strategies for diabetes prevention among adults.

제사부(第四部): 포스터발표(發表) 연제(演題) : 6. GC-FPD방법을 이용한 우유의 잔류유기인계농약 분석에 관한 연구

윤은선,황래홍,김현정,김연주,김동언,한인규,이병동 한국가축위생학회 2001 학술대회논문집 Vol.2001 No.-

여름철 안전운동 가이드

윤은선 한국스포츠정책과학원(구 한국스포츠개발원) 2020 스포츠과학 Vol.151 No.-