춘계학술대회 : 일반포스터 ; 소아에서 발생한 골격외 연골종 2예

오지은,전혜주,김소영,최유원,최혜영,명기범 대한피부과학회 2006 초록집 Vol.44 No.10

Autophagy as an Innate Immune Modulator

오지은,이흥규 대한면역학회 2013 Immune Network Vol.13 No.1

Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which in turn modulate innate immune responses. More specifically, autophagy acts as a direct effector for protection against pathogens, as well as a modulator of pathogen recognition and downstream signaling in innate immune responses. In addition, autophagy controls autoimmunity and inflammatory disorders by negative regulation of immune signaling. In this review, we focus on recent advances in the role of autophagy in innate immune systems.

IPA 분석을 통한 영·유아 식생활 교육 효과 평가

오지은,강남이,윤혜려,김주현 동아시아식생활학회 2018 동아시아식생활학회 학술발표대회논문집 Vol.2018 No.6

청소년의 신체적 특성, 신체활동과 정신건강문제와의 관계에서 주관적체형인식의 매개효과: 성별 간 다집단 분석

오지은 사단법인 인문사회과학기술융합학회 2018 예술인문사회융합멀티미디어논문지 Vol.8 No.1

The purpose of this study is to identify the structural relations among age, BMI, physical activity, subjective body perception, and a mental health problem in adolescents, and to examine whether subjective body perception would mediate the relation among physical characteristics, physical activity and mental health problem. This study was conducted using the data from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V). The subjects of this study were 606 male and female adolescents aged 12-18. The collected data were analyzed by the SPSS 18.0 and Amos 20.0 programs to verify the descriptive statistic, t-test, structural equation modeling(SEM). The results were as follows. First, subjective body perception significant effects on the mental health problem in adolescents. And subjective body perception partially mediate the relation among physical characteristics, physical activity and mental health problem. Furthermore there was differences of this results between male and female adolescents. the subjective body perception did not have and effect on the mental health in male adolescents. However the subjective body perception have a significant effect on the mental health in female adolescents. 이 연구는 청소년들의 정신건강문제에 영향을 미칠 것으로 예견되는 연령, 체질량지수, 신체활동, 주관적 체형인식 간의 구조적인 관계를 알아보고, 주관적 체형인식이 청소년의 연령, 체질량지수, 신체활동과 정신건강문제와의 관계에서 매개효과를 나타내는지를 살펴보고자 하였다. 또한 이러한 결과가 성별에 따른 차이가 있는지를 검증하고자 하였다. 이를 위하여 국민건강영양조사 제5기 3차년도 자료를 이용하였다. 만 12세 이상 18세 이하 남, 녀 청소년 중 결측값이 있는 데이터를 제외한 606명을 분석하였다. 분석은 SPSS 18.0과 AMOS 20.0 프로그램을 이용하여 기술통계, t-검증, 구조모형 분석을 하였다. 그 결과, 주관적 체형인식은 청소년의 정신건강에 영향을 미치는 의미 있는 요인으로, 자신을 더욱 비만하게 여기는 주관적 체형인식이 증가할수록 정신건강문제가 증가하였다. 또한 주관적 체형인식은 연령과 체질량 지수와 정신건강문제를 부분 매개하는 효과를 나타내었다. 그리고 이러한 결과는 성별에 따른 차이가 나타나서 남자 청소년에게 주관적 체형인식은 정신건강문제로 이어지지 않지만, 여자 청소년에게 있어 주관적 체형인식은 정신건강문제를 증가시키는 요인으로 나타났다.

Empirical antibiotics for recurrent urinary tract infections in children

오지은,최현길,이지영 고신대학교(의대) 고신대학교 의과대학 학술지 2018 고신대학교 의과대학 학술지 Vol.33 No.2

Objectives: The purpose of this study was to compare antibiotic resistance patterns between first urinary tract infection (UTI) and recurrent UTI groups and to obtain information regarding empirical antibiotic selection for treating recurrent UTI. Methods: We retrospectively reviewed 148 children treated for UTIs from January 2009 to June 2016. The patients were divided into two groups: first UTI (N = 148) and recurrent UTI (17 patients and 20 episodes). Results: In both groups, Escherichia coli was the most frequent causative organism, accounting for 89.9% and 75.0% in the first and recurrent UTI groups, respectively. When E. coli or Klebsiella pneumoniae was the causative organism, extended-spectrum β-lactamase (ESBL)-producing organisms were more frequent in the recurrent UTI group (17.6%) than in the first UTI group (14.0%); however, this difference was not statistically significant (P = 0.684). Cefotaxime was the most frequently used first-line empirical antibiotic in both groups. In the first UTI and recurrent UTI groups, 7.4% and 15.0% of patients were treated with intravenous antibiotics as definitive therapy, respectively (P = 0.250). Fifteen out of 17 patients having a second UTI had different causative organisms or antibiotic susceptibility patterns compared to their previous episode. Conclusions: Escherichia coli was the most frequent causative organism in the recurrent UTI group. There were no differences in the proportion of ESBL-producing organisms between the first UTI and recurrent UTI groups. Therefore, when a UTI recurs in children, the antibiotics effective on the most common causative organism might be administered as empirical antibiotics.

다속성 효용이론을 적용한 운전자 특성별 경로 선택 연구

오지은,배상훈 한국ITS학회 2011 한국ITS학회논문지 Vol.10 No.3

산업의 다각화로 지역간은 물론이고 도시내 자동차 통행량이 증가하고 있다. 고령자 및 여성 운전자의 수도 해마다 증가하는 추세에 있다. 이에 본 연구의 목적은 다양한 운전자 계층을 대상으로 경로별 속성에 대한 선호도를 조사하여 운전자 계층별 특성이 반영된 경로를 제시하고자 한다. 운전자 계층은 크게 성별, 연령별, 운전경력별로 구분하고 이러한 운전자 특성에 맞게 도출된 경로를 최단경로와 비교하였다. 운전자 계층별 특성에 따른 경로별 선호도를 파악하기 위해 다속성 효용이론(MAUT)을 적용하였다. 차로수, 사고건수, 경사도 등 경로속성에 대한 가중치 도출 결과, 구간길이 0.282, 제한속도 0.237, 차로수 0.191, 경사도 0.162, 사고건수 0.129로써 경로 선택 시 구간길이를 가장 선호하는 것으로 파악되었다. 사례지역을 대상으로 운전자 특성에 맞는 최적경로 도출 결과 남성운전자는 여성운전자에 비해 전체 링크의 구간길이는 1.25km단축되고 차로수가 더 많은 신속한 경로를 선호하였다. 고령운전자는 일반운전자에 비해 사고건수가 적은 안전한 경로를 선호함을 알 수 있었다. 또한, 운전 경력 1년 미만의 운전자는 숙련된 운전자에 비해 차로수가 많고 사고가 많이 발생하지 않는 안전하고 편리한 경로를 선호 하였다. 따라서, 현재 최단경로에 국한되어 있는 네비게이션을 통한 경로정보제공에 있어 운전자 계층의 특성을 반영한 정보 제공 다양화의 필요성이 본 연구를 통해 입증되었다. Traffic volume increases due to diversification of industry. Also, Automobile ownerships also increase steadily. It is estimated that the registered number of vehicle is expected to be 20 milion in the year 2015. These trends may result in increasing the number of woman drivers and elderly drivers. Therefore, this study aims to identify routes that reflect characteristics of each driver's preferences. A survey was conducted on different routes attributes for variances drivers. Driver types were classified by gender, age, and driving career. Accordingly, a weight for road composition attribute such as number of lanes, number of accidents, slope was estimated by using Swing Weighting technique in Multi-Attribute Utility Theory. In addition, a case study was conducted and identified weights were applied to routes. In result, drivers commonly prefer short route when they considered their routes. Also, male drivers prefer speedy and shorter route than that of female drivers. Elderly drivers prefer safe routes that represent low accidents rate. Moreover driving career under a year drivers prefer safe and easy routes. Therefore, we may conclude that the necessity of diversified route information is essential in the future car navigation system.

천연 쪽 분말 염료의 성분과 염색특성에 관한 연구

오지은,안춘순 한국의류학회 2010 한국의류학회 학술대회논문집 Vol.2010 No.-

유아 일상스트레스 척도 개발 및 타당화

오지은,임여정,이순형 한국열린유아교육학회 2016 열린유아교육연구 Vol.21 No.1

The purpose of this study was to develop a daily stress for preschool children scale which was established and differentiated for clearer and easier conceptual understanding. The items of the questionnaire were suitably matched to each sub-factor and reflected the changes of the era. A total of 222 5-year-old of preschoolers were examined by the designed questionnaire for this study. A scale that consisted of 20 items and 6 factors was induced by exploratory factor analysis. The construct validity of this scale was verified by confirmatory factor analysis and Pearson correlation. The concurrent validity was confirmed by Pearson correlation analysis between daily stress scale for preschool children and CBS(Child Behavior Scale), as well. Furthermore, the reliability of this scale was verified by Cronbach's α analysis. In conclusion, it demonstrated the reliability and validity of the daily stress scale for preschool children developed in this study as useful tools. 이 연구의 목적은 개념적으로 보다 명확하고 이해하기 용이하도록 하위요인을 설정하고 각 하위요인에 적합하며, 시대의 변화가 반영된 문항으로 구성된 유아 일상스트레스 척도를 개발하기 위한 것이다. 또한 통계적으로도 그 타당성을 면밀히 검증하고자 하였다. 이를 위하여 유치원에 재원중인 만 5세 유아 222명을 대상으로 질문지를 이용한 조사를 실시하였다. 먼저, 문항분석과 탐색적 요인분석을 실시한 결과 6개의 요인, 20문항으로 구성된 유아 일상스트레스 척도가 도출되었다. 다음으로 확인적 요인분석과 상관분석을 통해 이 척도의 구조가 타당한 것으로 검증되었다. 그리고 유아행동척도와 상관관계를 분석한 결과 공인타당도가 확인되었다. 마지막으로 내적합치도와 신뢰도 계수를 산출한 결과 통계적으로 신뢰가능한 척도임이 판명되었다. 따라서 이 연구에서 개발한 척도는 유아의 일상스트레스를 측정하기에 적합한 도구임을 알 수 있다.

Compressed-sensing (CS)-based Micro-DTS Reconstruction for Applications of Fast, Low-dose X-ray Imaging

오지은,조효성,홍대기,이민기,박연옥,Uikyu Je,김효정,이선하,최성일,Yangseo Koo,조희문 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.7

In this paper, we introduce limited-angle tomography in which the object being imaged is rotated around the center of an inclined X-ray beam, the so-called <i>micro-DTS</i> (digital tomosynthesis), with a few-view image reconstruction based on the compressed-sensing (CS) theory for applications of fast, low-dose X-ray imaging. We implemented an effective CS-based reconstruction algorithm for micro-DTS and performed systematic simulation works. The assessment of the image characteristics was performed by using several figures of merit such as the root-mean-square error (RMSE), the contrast-to-noise ratio (CNR), and the universal image-quality index (UQI) to compare the reconstructed images to the simulated phantoms. According to our results, compared to the FBP-based method, the CS-based reconstruction method substantially enhanced image accuracy against image artifacts from few-view and limited-angle projections. In the simulation, 41 projections were used for the half-tomographic angles of 30˚, 45˚, and 60˚, giving UQI values of 0.92 ∼ 0.97, which seems promising for potential applications of fast, low-dose X-ray imaging.

인터넷 배너광고의 유형에 따른 광고 효과

오지은,김성희,이상빈 전북대학교 사회과학연구소 2003 지역과 세계 Vol.29 No.-

This study was to investigate the effect of internet banner types(texts, animations, sexy models) on indexes of advertising effects(attitude toward the advertisement( A_ad), brand attitude( A_b), purchase intention(PI)]. In this study, 180 subjects were conveniently sampled, and randomly assigned to one of 6 conditions in 3(ad types) × 2(products types) factorial design. The major findings of this study as follows. The results of A_ad on differences compared with the ad using texts and sexy models. And the ad for computers had statistically significant differences from ad for books. The results of A_b on ad types had significant main effects, but the results of A_b on products types and interaction effects had no significant differences. The ad using texts and animations had statistically significant differences from the ad using sexy models. The results of PI on ad types had significant main effects, but the results of PI on products types and interaction effects had no significant differences. The ad using texts and animations had statistically significant differences from the ad using sexy models. Finally, implications and limitations of this study were discussed.