전염성 연속종의 한약 치료에 대한 임상 연구 동향- 2000년대 이후 발표된 임상 연구 논문을 중심으로 -

도태윤,박슬기,이선행,이진용 대한한방소아과학회 2019 대한한방소아과학회지 Vol.33 No.1

Objectives The purpose of this study is to investigate recent clinical studies on the effect of herbal medicine in molluscum contagiosum in China, and to seek better methods to treat and study for molluscum contagiosum in Korea. Methods We searched the clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) by key words ‘传染性软疣’, ‘治疗’, ‘中医治疗’, ‘中药’ from January 2001 to August 2018. We analyzed the literature in regards to the treatment methods and results. Results Among the 103 searched studies, 9 randomized controlled trials, 2 controlled clinical trials, and 16 case studies were selected and analyzed. In most of the studies, the effectiveness of herbal medicine on molluscum contagiosum was significantly high. The most commonly used herbs for oral administration were Isatidis Radix (板藍根), Coicis Semen (薏苡仁), Cyperi Rhizoma (香附子), Equiseti Herba (木賊), Poria (茯苓), Lithospermi Radix (紫草), Isatidis Folium (大靑葉) and Lonicerae Flos (金銀花). The most commonly used herbs for external applications were Isatidis Radix (板藍根), Lonicerae Flos (金銀花), Cyperi Rhizoma (香附子), Equiseti Herba (木賊), Dictamni Radicis Cortex (白鮮皮), Isatidis Folium (大靑葉) and Brucea javanica (鴉膽子). Conclusions Based on the results of the clinical studies from China, the use of Korean medicine for treatment of molluscum contagiosum has been shown to be effective in relieving symptoms. Based on the result of this study, it will be possible to widen the scope of Korean medicine on infectious disease, such as molluscum contagiosum. Additional clinical studies and experimental studies need to be performed to solidify these findings.

자폐 스펙트럼 장애의 한의학적 병인, 변증, 치법, 처방에 대한 문헌적 고찰 -중의학 논문을 중심으로-

도태윤,이선행,이진용,장규태,Doh, Tae Yun,Lee, Sun Haeng,Lee, Jin Yong,Chang, Gyu Tae 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.2

Objectives The purpose of this study is to provide evidence of pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder by reviewing journal articles published in China. Methods We searched literatures dated up to 8 January, 2018 in China National Knowledge Infrastructure (CNKI), and evaluated pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. Results Thirty four studies were selected for analysis. These studies included pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. The most common pattern differentiations were the pattern of kidney essence depletion, pattern of phlegm confounding the orifices of the heart, pattern of dual vacuity of the heart and spleen, pattern of effulgent heart-liver fire, pattern of liver failing to course freely. The most common treatment principles were supplementing the kidney, transquilizing, fortifying the spleen, transforming phlegm, opening the orifices, and calming the liver. The most commonly-used formulas were Yukmijihwangtang (六味地黃湯), Modified Ondamtang (加味溫膽湯), Guibitang (歸脾湯), Yangsimtang (養心湯), Jwaguihwan (左歸丸), Cheonmagudeungeum (天麻鉤藤飮), and Danchisoyosan (丹梔逍遙散). Conclusions This study shows the latest trend of pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. Further study is needed to solidify these findings.

CNKI 검색을 통한 중국에서의 성장통의 한의학적 치료에 대한 임상연구 동향

도태윤,박슬기,이선행,이진용 대한한방소아과학회 2019 대한한방소아과학회지 Vol.33 No.2

Objectives: The purpose of this study is to investigate clinical studies on the effectiveness of Traditional Chinese Medicine treatment on growing pains in China, and to seek better methods to treat and study for growing pains in South Korea. Methods: The clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) that were published up to January 2019 were reviewed. The key word used were ‘生长痛’, ‘发育期痛’, ‘治疗’, ‘中医治疗’, ‘中药’. Then, the literature were analyzed in regards to the treatment methods and results. Results: Among the 35 searched studies, 1 randomized controlled trials, 16 case series, and 3 case reports were selected and analyzed. In most of the studies, the effectiveness of Traditional Chinese Medicine treatment on growing pains was significantly positive. The most commonly used herbs for oral administration were Glycyrrhizae Radix et Rhizoma (甘草), Achyranthis Bidentatae Radix (牛膝), Paeoniae Radix Alba (白芍藥), Dioscoreae Rhizoma (山藥), Angelicae Gigantis Radix (當歸), Astragali Radix (黃芪), Atractylodis Rhizoma Alba (白朮), Poria Sclerotium (茯苓) Rehmanniae Radix Preparata (熟地黃), Lycopodii Herba (伸筋草). Other treatment methods such as, external application of herb medicine, massage, acupuncture were also used to treat growing pains. Conclusion: Based on the results of the clinical studies from China, the use of chinese medicine for treatment of growing pains has been shown to be effective. Additional clinical studies are needed to confirm these findings.

CNKI검색을 통한 중국에서의 태아성장지연에 대한 한약 치료 임상연구 동향

도태윤(Tae-Yun Doh),이선행(Sun-HaengLee),이진용(Jin-YongLee) 대한모유수유한의학회 2018 대한모유수유한의학회지 Vol.4 No.1

Objectives:Thepurposeofthisstudyistoinvestigateclinicalstudiesontheeffectof herbalmedicineonferalgrowthrestrictioninChina,andtoseekbettermethodstotreat andstudyforfetalgrowthrestrictioninKorea. Methods:Wesearchedtheclinicalstudiesfrom theChinaAcademicJournal(CAJ)in ChinaNationalKnowledgeInfrastructure(CNKI)by key words‘宫内发育迟缓’,‘治疗’, ‘中医治疗’,‘中药’from January 1994toNovember2018.Weanalyzed theliteraturein regardstothetreatmentmethodsandresults. Results:Amongthe92searchedstudies,10randomizedcontrolledtrials,6controlled clinicaltrials,and7casestudieswereselectedandanalyzed.Inmostofthestudies,the effectivenessofherbalmedicineon molluscum contagiosum wassignificantly high.The mostcommonlyusedherbsfororaladministrationwereAstragaliRadix(黃芪),Angelicae GigantisRadix(當歸),AtractylodisRhizoma White(白朮),TaxilliRamulus(桑寄生), SalviaeMiltiorrhizaeRadix(丹蔘)andCnidiiRhizoma(川芎).Themostcommonlyused medicinesforinjectiontherapieswereSalviamiltiorrhizaeRadix(丹蔘)+Tetramethylpyrazine. Conclusions: Based on the resultsofthe clinicalstudiesfrom China,the use of Koreanmedicinefortreatmentoffetalgrowthrestrictionhasbeenshowntobeeffective. Additionalclinicalstudiesandexperimentalstudiesneedtobeperformedtosolidifythese findings.

신계허약아 진단을 위한 절단값 산정 연구-신장, 체중, 골연령을 기준으로

김태환,서혜선,도태윤,이선행,이진용 대한한방소아과학회 2023 대한한방소아과학회지 Vol.37 No.4

Objectives This study aimed to evaluate the correlation between pediatric weakness scale scores and growth indices. Furthermore, we intended to calculate the cut-off values for diagnosing Kidney Weak Children through growth indices. Methods A total of 193 patients, aged 6 - 12 years, underwent both the pediatric weakness scale and bone age assessment, and the correlations between the pediatric weakness scale and growth indices were analyzed. Moreover, the cut-off values for diagnosing Kidney Weak Children were calculated. Differences in bone age and predicted height between the normal group and Kidney Weak Children, classified according to the calculated cut-off values, were analyzed. Results The weakness of the Shin or kidney system was significantly correlated with the height percentile, weight percentile, differences in current height percentile and mid parental height percentile, differences in predicted height and mid parental height, and differences in bone age and chronological age. When the criteria for diagnosing Kidney Weak Children is set at “height percentile of ≤25% and weight percentile of ≤25%”, the sensitivity and specificity of the cut-off value were maximized. The cut-off values for weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years. Conclusions To diagnose Kidney Weak Children, the cut-off values of weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years.

야제 (夜啼)의 한의학 치료에 대한 최신 중의학 임상 연구 동향 -2000년대 이후 발표된 임상 연구 논문을 중심으로-

김상민,이진용,이선행,도태윤,Kim, Sang Min,Lee, Jin Yong,Lee, Sun Haeng,Doh, Tae Yun 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.3

Objectives The purpose of this study is to analyze some of the TCM (traditional Chinese medicine) clinical research literatures about pediatric night crying in order to learn clinical application of Korean medicine treatment for pediatric night crying. Methods We searched clinical trial literatures about TCM treatment of pediatric night crying from the CNKI (China National Knowledge Infrastructure) (January 2000 to June 2018). We analyzed the literature in regards to the treatment methods and the results. Results Among the 459 searched studies, 13 randomized controlled trials and 41 case studies were selected and analyzed. In most of the studies, the effectiveness of TCM in treating patients was significantly high, so we confirmed the effectiveness of TCM on pediatric night crying. The most commonly used pattern differentiations (辨證) were Spirit damage due to fright and fear (驚恐傷神), Spleen deficiency and cold (脾虛寒) and Heart fire heat (心火熱). Methods of treatment include herbal medicines (internal medicine and external application), massage therapy (Tuina methods), acupuncture and other treatments (bloodletting). The most commonly used herb medicines were Cicadidae Periostracum (蟬?), Poria Cocos (茯?), Glycyrrhizae Radix (甘草), Uncariae Ramulus et Uncus (釣鉤藤), Junci Medulla (燈心草), Fossilia Ossis Mastodi (龍骨), Atractylodis Rhizoma Alba (白朮), Cinnabaris (朱砂), and Coptidis Rhizoma (黃連). The most commonly used massage methods were Clearing Liver Channel (淸肝經), Clearing Heart Channel (淸心經), Kneading $Xi{\check{a}}oti{\bar{a}}nx{\bar{i}}n$ (?小天心), Supplementing Spleen Channel (補脾經), Clearing $Ti{\bar{a}}nh{\acute{e}}shu{\check{i}}$ (淸天河水), and Rubbing Abdomen (摩腹). Conclusions Based on the results of clinical studies from China, the use of Korean medicine for the treatment of pediatric night crying has been shown to be effective in relieving symptoms. Based on the results of this study, it is possible to widen the scope of Korean medicine by additionally reviewing clinical and experimental studies on pediatric night crying.

소아 류마티스 관절염으로 인한 경피증에 대한 한방복합치료 증례보고 1례

박소현,이진용,이선행,도태윤 대한한방소아과학회 2019 대한한방소아과학회지 Vol.33 No.4

Objectives: This study is to report a case on a patient with Scleroderma Caused by Juvenile Rheumatoid Arthritis. This patient’s symptoms were improved by the Complex Korean Medicine Treatment. Methods: The patient was treated for 20 days with acupuncture, moxa treatment, physical therapy, herbal medicine (Ganghwalbinsosan, 羌活檳蘇散), and herbal dressing therapy(Dohongsamultang, 桃紅四物湯). Results: NRS and mRSS were used to assess patient’s symptoms daily morning and to observe the changes of symptoms. After 20 days of the treatments, the patient showed remarkable improvement of the main symptoms of pain, pruritus and scleroderma of left leg. Conclusions: This case study showed that symptoms in patient with Scleroderma Caused by Juvenile Rheumatoid Arthritis were significantly improved by the Korean medicine treatment, such as acupuncture, moxa treatment, herbal medicine, and herbal dressing therapy.

A comparison of the effects of dexamethasone-pharmacopuncture and dexamethasone-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

김재학,강도영,강민수,강보라,강은별,강진석,고예진,고휘형,곽재영,구현정,권서연,기유미,김가연,김경묵,김경훈,김규리,김동현,김민우,김민채,김성호,김세윤,김시라,김신형,김영준,김종현,김지수,남선우,도태윤,도하윤,문기역,민경록,박경근,박민영,박성민,박인우,박준규,박준한,박정건,박지은,박태기,배준형,변정욱,서세욱,서혜진,손강민,송창규,신혜진,신희연,문필동 셀메드 세포교정의약학회 2013 셀메드 (CellMed) Vol.3 No.3

Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between dexamethasone-pharmacopuncture (DP) and dexamethasone-oral administration (DO), the effect of DP was investigated in murine models. Anti-anaphylactic effects of dexamethasone treatments were investigated in compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and passive cutaneous anaphylaxis (PCA). DP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and PCA. The effects between DP and DO were on a similar level. These results indicate that DP can be used as an alternative method for DO in case of emergency.