急性特發性心囊炎의 1例

金星潤,孫宜錫,李禎均,許鳳烈,咸駿洙,金鮮宙 대한의학협회 1977 대한의학협회지 Vol.20 No.9

正常및 異常分娩中 母體와 臍帶血漿의 β-endorphin 및 ACTH値의 變動에 關한 硏究

鄭求烈,李揆玩,李珉載,洪性鳳 고려대학교 의과대학 1987 고려대 의대 잡지 Vol.24 No.1

β-endorphin and adrenocorticotrophic hormone (ACTH) are derived from the same precursor protein and they have been implicated as the modulators of pain during the labor process. To investigate their possible role during labor this study was undertaken to determine the levels of β-endorphin and ACTH during labor and delivery in healthy term pregnant women and their neonates after delivery. β-endorphin and ACTH were measured by radioimmunoassay in 22 spontaneous labors, 14 elective cesarean sections and 7 emergency cesarean sections during early and late labor, and after delivery. The results obtained are as follows: 1. In cases of spontaneous vaginal delivery and emergency cesarean section, maternal plasma β-endorphin and ACTH levels were significantly increased during late labor and remained and continuously elevated during the first postpartum hour. 2. In cases of elective cesarean sections, maternal mean plasma levels of β-endorphin and ACTH were significantly lower than levels in spontaneous vaginal deliveries and emergency cesarean sections. 3. There was a significant correlation between meternal plasma β-endorphin and ACTH levels during labor. 4. Umbilical arterial β-endorphin levels in newborn infants after spontaneous vaginal delivery and emergency cesarean section were significantly higher than levels in infants born by elective cesarean section, but only spontaneous vaginal deliveries showed higher umbilical arterial ACTH levels in newborn infants than infants born by elective cesarean section. 5. There was no relationship between meternal and umbilical cord plasma β-endorphin and ACTH. There was not significant correlation between umblical cord plasma β-endorphin and ACTH levels, and fetal weight and placental weight. 6. There was no correlation betwen umbilical arterial pH and Apgar score by mode of delivery, but statistical significance was found to exist in the umbilical arterial pH of emergency cesarean sections and elective cesarean sections. Present studies suggest that β-endorphin and ACTH are significantly increased during late labor due to stress and pain, and hypoxia may be important physiologic stiumuli controlling the release of β-endorphin and ACTH in the human fetus.

대기압 플라즈마에 의한 냉간압연 스테인리스 Micro-Cleaning판재의 에 관한 연구

오상훈,이성기,윤재홍,조동율,박봉규,이성규 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

Atmospheric Plasma Cleaning (APC) was studied for the residual rolling oil contaminants on the surface of cold rolled Stainless Steel after optimizing APC conditions. Electrodes were placed at a distance of 10mm, with an RF power of 220W, and line velocity of 0.5m/min. The residue left by APC was 0.78mg/m², which was less than that of the approximate 1mg/m² by other classical cleaning methods. Especially, APC combined with pre-cleaning by 550℃Nitrogen gas gave a residue of only 0.01mg/m². Cleaning effect are also improved when oxygen gas is added to the atmospheric plasma. It was confirmed by the investigation of the official Korea Chemical Analysis Center that the APC-hot nitrogen method is superior to other methods. The residual contaminants for different methods were as follow : the classical method : about 1mg/m², APC : 0.78mg/m², and APC-hot nitrogen : 0.10mg/m².

2-Propanol-물 혼합용매에 대한 n-Alkylamine 염산염의 Partial Molal Volume에 관한 연구

윤상기,엄태섭,김봉규,박종열 東亞大學校 1977 東亞論叢 Vol.14 No.-

2-propanol-물 혼합용매계에 대한 n-alkylamine 염산염의 "겉보기몰랄부피" ø??를 부력법을 이용하여 30℃에서 측정하였다. Amine염 C??H??NH??Cl은 C??에서 C??에 이르는 저급 동족체를 시료로 하고 혼합용매 각 조성마다. 0.01M~0.2M 농도범위안의 용액에 대한 float의 무게를 소수점이하 5위까지 평량하였다. Limiting law equation에 의거 농도의 평방근 √vsø?? plot한 것을 C→0 즉 무한대의 묽은 쪽으로 extrapolation 함으로서 "분몰랄부피"V를 구하였다. 실험결과는 농도변화와 용매조성에 따른 ø?? 및 V의 변화, limiting slope S'와 ion의 charge effects 등에 대하여 논의하였다. 즉 √대 ø?? plot의 결과는 기울기가 크고 positive한 두 직선이 생기는데 이것이 √ 0.2부근에서 예리하게 교차되는 것이 관측 되었다. 또한 0.2m.f. 조성 때에 maximum의 S'와 minimum의 V?? 값이 나타나고 아울러 ion의 charge effect가 maximum임을 알았다. 실험결과는 또한 같은 시료를 methanol-물, ethanol-물 혼합계에 각각 적용한 결과와 비교하여 논의하였다. The apparent and partial moral volumes (ø?? and V??) of the lower homologous salts of n-alkylamine hydrochloride C??H??NH??Cl where C?? varies from C?? to C?? have been determined to the fifth decimal place at 30℃ by means of float method in 2-propanol-water mixtures, and the values of ø?? extrapolated to infinite dilution according to the limiting law equation give partial molar volumes. The experimental results are discussed in terms of the charge of ion and of the volume change in apparent molar volumes depend upon the increase of he concentration of the solutions and in partial molal volume according to the varing composition of mixed solvent. It has been observed that the plot of ø?? vs c?? showed sharp transition at approximately c?? 0.2 with anomalously positive and large slope, while the maximum charge effect related to the limiting slope S'?? causes minimum in V?? at 0.2 mole fraction of mixed solvent. It has been discussed and compared with respect to the results of the previous study as examined for the same sample species in methanol and ethnol-water mixtures respectively.

溫室保溫커튼의 材料特性에 따른 保溫效果分析

金榮福,金容換,李昇揆,金成泰,羅又禎,閔永鳳,朴重春,崔東烈 慶尙大學校 1991 論文集 Vol.30 No.2

The effects of the material properties of thermal curtains upon reduction of the greenhouse heat loss were studied. A theoretical analysis procedure with equations and computer programs was developed to estimate them by using energy balance principles. Curtain effectiveness for every three kinds pf value level of the material properties were studied and compared. The results of this study would be useful for the developent and management of greenhouse thermal curtains.

일부 생산직 근로자의 소음과 사회심리적 요인이 혈압에 미치는 영향

박종구,강명근,차봉석,고상열,장세진,고상백 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

This study was conducted to assess the effects of noise exposure and psychosocial factor on blood pressure in manufacturing workers. The study subjects are 414 workers(243 males, 171 females) employed at the noisy department. The mean age of low exposed group(<85dB) was 34.65±9.53 years, and that of high exposed group(≥85dB) was 36.37±11.15 years. The difference in mean age was not significant. The mean and distribution of working duration, smoking status, drinking status were not significantly different between two groups. The mean systolic blood pressure of the low exposed group was 120.01±12.06 mmHg, and that of high exposed group was 126.27±13.84mmHg. The mean diastolic blood pressure of the low exposed and the high exposed group were 77.18±10.83 mmHg, and 83.46±11.22mmHg respectively. These differences of blood pressure were statistically significant(p<0.05). The workers in noisy department have significantly less work environmental satisfaction, higher job demand, and higher social support. The mean values of psychosocial distress were higher in the workers of the noisy department, but the difference was not statistically significant. This study was to speculate whether the work environmental satisfaction and social support modify the association between the noise exposure level and the blood pressure. The result showed that work environmental satisfaction could not modify the association between the blood pressure and the noise exposure. Social support at work did not modify the association. Furthermore, we evaluated the high job strain from a combination of ratio of the high job strain group for hypertension in diastolic blood pressure were statistically significant, but not in systolic blood pressure. Hierarchical multiple regression analysis was used to determine whither the independent variables contributed to explaining the blood pressure. After controlling for possible confounders, we found that the noise exposure level was a correlated of the diastolic blood pressure. But no association between the noise exposure level and the systolic blood pressure. No significant result was found for psychosocial factor.

조갑진균증의 치료에서 터비나핀과 이트라코나졸의 이중맹검 비교연구 : 공동연구

김기홍,최종수,송준영,김상원,김수찬,안성구,성열오,서순봉 대한화학요법학회 1995 대한화학요법학회지 Vol.13 No.2

저자들은 새로 개발된 alyllamine계 항진균제인 터비나핀의 발톱의 조갑백서에서 치료 효과, 내약성 및 부작용 등을 평가하기 위해 triazole계의 이트라코나졸과 이중 맹검으로 비교 조사하였다. 치료방법은 터비나핀은 250㎎/days로 12주간, 이트라코나졸은 100㎎/day로 124주간 복용하고 양군 모두 치료 시작 후 36주까지 추적 관찰하였다. 조사방법은 조갑진균증 환자에 대해 치료에 대해 설명후 동의서를 받고 장기간 치료가 부적합한 경우를 제외한 149명(터비나핀군 74명, 이트라코나졸군 75명)이 치료를 받았으며 이중 25명이 탈락하고 13명이 부작용등으로 치료를 중지하여 111명(터비나핀군 51명, 이트라코나볼군 60명)이 치료를 완료하였다. 1. 임상적인 소견은 점진적으로 호전되었으며, 치료 시작후 36주에는 병변조갑의 감소 비율로 볼때 터비나핀군은 51명중 완전치료가 24(47.0%), 76%이상 호전이 18명(35.3%), 51%~75% 호전이 6명(11.8%), 26~50% 호전이 2명 (3.9%), 25% 이하의 호전을 보인 예는 1명(2.0%)였다. 이트라코나졸군은 60명중 완전치료가 27(45.0%), 76% 이상 호전이 14명(23.3%), 51%~75%호전이 9명(15.0%), 26~50% 호전이 2명(3.9%), 25% 이하의 호전을 보인 예는 1명(2.0%)였다. 이트라코나졸군은 60명중 완전치료가 27(45.0%), 76% 이상 호전이 14명(23.3%), 51%~75%호전이 9명(15.0%), 26~50% 호전이 7명 (11.7%), 25% 이하의 호전을 보인예는 3(5%)였다. 2. KOH도말 검사에서 음성 소견을 보인 비율은 터비나핀은 24주 후 50예(98.0%)였으며, 36주후에는 모두 음성을 나타내었고, 이트라코나졸은 치료 24주 후 51예(85.0%)였고, 36주후에는 59예(98.3%)에서 음성을 나타내었다. 진균배양 검사에서는 치료 12주 후에 터비나핀군은 51예중 44예에서 (86.3%), 이트라코나졸군은 60예중 52예에서 각각 음성이었으며(86.7%), 치료 36주 후에는 양군 모두에서 음성이었다. 3. 내약성은 양군 모두 시간이 지나면서 증가하였으며, 터비나핀은 moderate이상이 98~·00%였고, 이트라코나졸은 moderate이상이 96.7~100%였다. 4. 부작용은 위장관 증상이 가장 많았고 터비나핀은 23명, 이트라코나졸은 37명이었고, 2명, 3명에서 각각 일시적인 간효소치의 상승이 있었다. 이상의 결과로 보아 조갑진균증의 치료에 터비나핀 1일 250㎎씩 12주간의 경구투여는 치료율, 안정성 및 부작용에서, 추천할 만한 치료법이라 생각된다. In this randomized double-blind trial on multicenter study, the efficacy of the new antifungal agent, terbinafine(Lamlsil) was compared with the triazole antifungal agent, itraconazole, in the treatment of patients with onychomychosis. One hundred and forty nine patients(74 terbinafine, 75 itraconazole) with onychomlychosis were enrolled. Twenty five patients were lost to follow up and 13 reported adverse reaction with premature discontinuation of therapy. And 111 patients were eligible for follow-up until 36 weeks after starting the treatment. Fifty one patients received Lamisil(terbinafine) 250mg daily for twelve weeks (terbinafine group) and 50 received itraconazole 100mg daily for 24 weeks (itraconazole group). They were checked clinical symptoms(onycholysis, subungual hyperkeratosis, paronychyal inflammation, color change, brittleness, ridging, normal length of nails) and mycological improvement with KOH wet mount and culture during the study. Clinical improvements were slow but progressive. In terbinafine group of 5t patients, 24 patients(47.0%) were completely cleared and 18 patients(35.3%) were improved more than 76%, and 6 patients(11.8%) were improved in 53-75%. In itraconazole group of 60 patients, 27 patients(45.0% ) were completely cleared and 14 patients(23-3%) were improved more than 76%, and 9 patients(150%) were improved in 51-75% . In mycologic study, cure rate of the terbinafine group showed all negative at 36 week after the treatment while ittraconazole group showed all negative in culture but negative KOH in 98.3%. Adverse reactions and tolerability of both the drugs were good and net different significantly. All these findings suggest that the efficacy of Lamisil(terbinafine) 250mg daily for 12 weeks in the treatment of onychomycosis was similar to that of itraconazole 100mg daily for 24 weeks.

치근 피개를 위한 조직재생유도술식 : 문헌적 고찰

김성봉(Sung Bong Kim),조세열(Se Yul Cho),한경윤(Kyung Yoon Han) 조선대학교 구강생물학연구소 1999 Oral Biology Research (Oral Biol Res) Vol.23 No.1

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Hydrogen for the Future Green Energy

( Ha Suck Kim ),( Sung Yul Bong ),( Seung Hee Woo ) 경남대학교 신소재연구소 2012 신소재연구 Vol.24 No.-

Many agree that the future energy will be hydrogen after the recent energy crisis which brought us to reconsider seriously about possible alternatives after fossil fuel for mankind. There are abundant sources for hydrogen-water, and it burns to form water. However, in order for us to adopt the new energy system, many hurdles have to be overcome. They are how to produce hydrogen economically, ways to store and transport safely, and ways to generate electricity efficiently, to name a few. Electrochemical generation of hydrogen needs a high overvoltage, thus, it is a very expensive way at the moment. Also, storage and transport require many fundamental researches. Efficient use of hydrogen is fuel cell. Fuel cells have been received a considerable interest as power sources because they exhibit high energy efficiency and are environmentally friendly. Despite these advantages, fuel cells in general need to overcome economic barriers for wide applications. Main barriers are the cost of materials such as platinum used in catalysts and proton conducting polymer. Catalysts are the core material for fuel cell and many attempts have been made to find out the most active, efficient and durable formulae in the MEA preparation step.[1-2] In this respect, works performed in our group for fuel cell catalysts will be summarized, they are preparation of by galvanostatic pulse electrodeposition on Nafion-bonded carbon layer [3-5], and effect of carbon supports for catalysts. Improved catalytic performance by choosing appropriate flow channels in the support was also observed. Also in this presentation, energy statistics and efficient way of use energy, possible future energy scheme will be discussed. [1] Hubert A. Gasteiger, Shyam S. Kocha, Bhaskar Sompalli, Frederick T. Wagner, Applied atalysis B: Environmental56(2005)9-35. [2] Seunghee Woo, In Kim, Jae Kwang Lee, Sungyool Bong, Jaeyoung Lee, Hasuck Kim, Electrochim. Acta, 56(2011) 3036-3041. [3] Youngmi Ra, Jaeseung Lee, In Kim, Sungyool Bong, Hasuck Kim, J. Power Sources, 187, 363-370 (2009). [4] J. Lee, Kookil Han, Hasuck Kim, J.PowerSources, 163(2006)349-356. [5] Sungyool Bong, Yang-Rae Kim, Seunghee Woo, Sunghyun Uhm, Jaeyoung Lee and Hasuck Kim, Electrochem. Commun., 12, 129-131 (2010).

골수이식 후 apoptosis를 보이는 표피에 관한 연구

이상률,박봉수,배승환,진영준,윤식,유기수,임영진,유영현 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.4