한우, 칡소 및 제주 흑우 Calpain-Calpastatin 유전자 다양성

이승환,김승창,조수현,최봉환,Aditi Sharma,임다정,당창권,장선식,김재환,고문석,양보석,강희설 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

The aim of study was to investigate genetic diversity for the calpain/calpastatin gene in three Hanwoo breeds [(Brown (n=62), Brindle (n=81) and Jeju Black (n=30)]. Random samples from three breeds of Hanwoo were selected and genotyped for the 7 SNPs of calpain/calpastatin using TaqMan method. Allele frequencies were investigated for CAPN1/CAST gene. Allele frequency of CAST2 SNP was 0.75, 0.59 and 0.22 for Brown, Brindle and Jeju black, respectively. The CAST3 revealed allele frequency of 0.59 and 0.57 in Brown and Jeju Black, while it showed very low allele frequency (0.07) in Brindle. In particular, favorable allele (G allele) for the CAPN1-2 SNP which was shown a strong association with tenderness in Taurine and Indicine cattle revealed 16% and 17% higher allele frequency in Brown Hanwoo (0.82) comparing Brindle (0.66) and Jeju Black Hanwoo (0.65). AMOVA demonstrated that among population variance occupied only 10% of total variance and among individual variance was 0%, while within individual variance was 90% of total variance. This result showed that population effect contributed very small portion of genetic to these three Hanwoo breeds, while within individual variance contributed large portion of genetic diversity within these Hanwoo breeds. In conclusion, three Hanwoo breeds (Brown, Brindle and Jeju black) showed a genetically homogeneous based on the 7 SNPs of CAPN1/CAST gene and it came from same ancestor to form modern Hanwoo breed.

수도권 지역의 의료기기 관련 업체의 실태 조사 연구

양태홍,이우철,김정래,박승환 서울보건대학 1997 서울보건대학 부설 병원경영연구소 논문집 Vol.3 No.1

Recently, the domestic business of medical equipment have many difficult things in the development and sale of new product. To overcome them, it is needed to solidify the co-work system of industry-education marriage. This paper is undertakened to serve an aid in the field of medical equipment. The analysis of data is attempted through the survey by questionaires, and an object of study is the medical business corporation at Seoul area. As a result to review the data it was identifided that this study is able to be applied to the basis material to reconstruct a right role and phase to medical business Also, it`s expected that we're able to use its results as the educational materials to bring up the more qualified students fit to the industrial need.

경도관 동맥색전술을 이용한 비정상 자궁출혈의 치료

양승부,최교창,이상진,정영진,임한혁,한효상,황인철,조환성 순천향의학연구소 2005 Journal of Soonchunhyang Medical Science Vol.11 No.1

Objective : Our purpose of this study is to evaluate the effectiveness of the transcatheter arterial embolization for the management of abnormal uterine bleeding. Materials and Methods : 14 patients with massive or recurrent uterine bleeding underwent percutaneous transcatheter arterial embolization between February 2003 and September 2004. We reviewed 14 cases of uterine artery or internal iliac artery embolization using gelfoam or PVA particles. Results : Good management of uterine bleeding was achieved in 13 of 14(93%) cases. The cause of abnormal uterine bleeding was myoma(5 case), post D & E bleeding(3), acquired vascular malformation(3), pseudoaneurysm(1), adenomyosis(1), and endometrial hyperplasia(1). Conclusion : Transcatheter artery embolization is an effective and life-saving procedure in massive or recurrent uterine bleeding. Early diagnosis and prompt transcatheter arterial embolization is a useful mangement of uterine bleeding.

노인 외상 환자의 중증도 분류 시 Triage-revised Trauma Score의 의의

양영모,하영록,정성필,김승환,유인술 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Backgrouds: The mortality of geriatric trauma patients is higher than that of other age groups. However, little research has been done the methods or criteria of triage for geriatric trauma patients. This study evaluated a clinical significance of the triage-revised trauma score(t-RTS) for triage of geriatric trauma patients. Methods: We retrospectively analyzed clinical data on 528 trauma patients over 65 years of age who were treated from Jan 1999 to Dec 2000. The t-RTS was calculated utilizing the RR(respiratory rate), SBP(systolic BP), and GCS scores and the ISS was abstracted from the final diagnosis. The obtained t-RTS and ISS were evaluated using the measures of sensitivity, specificity, accuracy, and AUC curve. Results: The overall mortality rate was 9%, and there was no significant differences between the survival group and the mortality group according to age and sex. The mean scores of SBP, RR and GCS of the survival group were significantly higher than those of mortality group(p=0.001). The mean of t-RTS and RTS of the survival group were also significantly higher(p=0.001), but the ISS was significantly higher in the mortality group(p=0.001). The t-RTS, RTS, and ISS showed good prediction rates on the ROC curve(p=0.001), and the AUC value was higher in the ISS than in the t-RTS and the RTS. The sensitivity and the accuracy were high in the t-RTS and the RTS, and the specificity was high in the ISS. The t-RTS is less than 10 for a survival probability of 50% or less Conclusions: Implementation of the t-RTS in the triage of geriatric trauma patients in the field and in emergency room would be very useful. The probability of death in geriatric trauma patients is high when the t-RTS is less than 10.

중부산간마을 외부공간 구성의 특성에 관한 연구 : 충북 영동의 마을을 중심으로 Focused on the Mountain Villages in Young-Dong district, Ch'ung-buk

양승정,김용승,박용환 漢陽大學校 工學技術硏究所 2001 工學技術論文集 Vol.10 No.-

본 연구는 충청북도 영동군에 있는 두 산간마을을 중심으로 공간통사론의 '정량적인 해석을 통하여 공간 구성의 특성을 파악하였다. 취락구조 및 외부공간구성에서 나타난 특성을 살펴보면 다음과 같이 나타나는데, 두 산간마을의 내부도로는 큰길-어귀길-안길-샛길-골목길 등 위계적인(전통적인) 길의 체계를 유지하고 있는데, 마을에 대한 외부인의 방문시에는 안길 등 통합적인 공간에서 영향이 크게 나타나고 있으며, 공간이 깊어질수록 거주자에게 영향이 크게 나타난다. 가옥의 좌향은 일조보다는 길을 향하여 배치가 결정되어 있으며, 주거의 마당은 통로로서 길의 역할도 수행하고 있어 거주자들은 마을에 대한 공동체의식에 대해 개방되어있다. 또한 두 마을은 경사의 형태에 따라 인지도와 접근성에 대해 각각 다른 차이를 보인다. This study examines the Space Syntax theory of the spatial system of settlement in central mountain villages by means of analyzing the spatial organization and the structural characteristics of the two mountain villages in Young-Dong district, Ch'ung-buk province. The conclusions are as follow: The village's street has a grade of rank in the exterior spatial structure, and it is found out one of the most important feature that the unification of inside street with the function for checking outsiders. Also, it is found out important feature that the lay of house in arrangement has been fixed by the street rather than the sunshine, and since a housing yard has been performed the part of street as the path, the residents are open to the community consiousness for the village. Also a couple village is distinct between the recognizability and approachability according to the slanted shape.

국제 쌀 가격의 동태적 분석 : 중립종과 장립종을 중심으로

양승룡,조재환 韓國農業政策學會 1997 농업경영정책연구 Vol.24 No.2

언어행위의 형식적 특성을 밝히기 위한 기초연구

양병환,민형원,홍성기,정승아 漢陽大學校 精神健康硏究 1998 精神健康硏究 Vol.17 No.-

Glycation 유발물질의 반응성의 비교

양용,이용갑,오두환,신동범,엄성용 한국노화학회 1993 한국노화학회지 Vol.3 No.1

발치 직후 시행된 즉시 임플란트 식립술에 관한 임상적 평가

양은영,천상득,노재환,이승은,송재철,진병로 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.1

Background: Immediate implant placement has become an acceptable treatment for the edentulous area. The advantages of the immediate implant placement include considerable decrease in time from tooth extraction to placement of the finial prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plans. But the success is dependent on the quantity and quality of the extraction socket. The purpose of this study is to evaluate the success of the immediate implant placement. Materials and Methods: Twenty-one sites in 16 patients were selected for the evaluation of the immediate implant placement. All of the cases were followed using clinical and radiographic examinations. Criteria of success were the absence of peri-implant radiolucency, mobility, and persistent pain or sign of infection. Results: Of the 21 implants, 13 implants have been succeeded. Of the 13 implants, 10 implants were replaced for the periodontal disease and 3 implants were replaced for the trauma. Conclusion: The criteria of the success in immediate implant placement are as follows. 1) Implants placed into fresh extraction sockets have a high rate of survival. 2) Implant should be placed as close as possible to the alveolar crest. 3) Implant placed into available bone beyond the apex have a high success rate.

Benztropine Mesylate가 Haloperidol 타액농도에 미치는 영향에 대한 연구

이승탁,사승언,양병환 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.3

Nineteen patients with schizophrenia by the DSM-III-R were administrated with only haloperidol in the first period. And the second period began after extrapyramidal symptoms developed, in this period they were administrated with haloperidol and benztropine concomittantly. At the third period, after withdrawal of benztropine, they were administrated with only haloperidol. For the purpose of evaluating the effect of benztropine mesylate on the haloperidol saliva level, the authors measured the haloperidol saliva level, the reduced haloperidol saliva level and the ratio of the reduced haloperidol saliva level/the haloperidol saliva level at the seperated administration period. The results are as follows : 1) Though the haloperidol saliva level of the single administration period of haloperidol was higher than that of other two periods, there was no statistically significant change. 2) The reduced haloperidol saliva level had no statistically significant change among three periods. 3) The reduced haloperidol saliva level/the haloperidol saliva level ratio had no statistically signifiant change among three periods. The authors concluded that the benztropine mesylate had no significant effect on the haloperidol saliva level in this study.