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분화갑상선암의 수술 후 국소재발 및 전이에 대한 FDG PET/CT와 초음파의 비교연구
김재환,이태현,김기환,박동희,최두환 대한영상의학회 2009 대한영상의학회지 Vol.61 No.5
Purpose: This study was designed to compare the accuracy of the use of PET/CT and ultrasonography (US) for the detection of recurrence or a metastasis after surgical treatment in patients with differentiated thyroid carcinoma. Materials and Methods: A total of 128 patients with differentiated thyroid carcinoma, who had previously undergone a neck operation, were evaluated with the use of PET/CT and US. The two studies were performed within three months of each other. The presence of a metastasis or recurrence was based on histological results. Statistical values for FDG PET/CT and US findings were calculated statistically. Results: Recurrence or a metastasis occurred in 40 of 128 patients. Thirty-one patients had lesions that were detected with the use of both PET/CT and US. Eight patients had lesions that were detected only with US. A lesion in one patient that had a high SUV on PET/CT was not detected by the use of US. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value for PET/CT were 80%, 82%, 82%, 68% and 90%, respectively. The corresponding values for US were 97%, 85%, 89%, 75% and 99%, respectively. The sensitivity and specificity for US were higher as compared to PET/CT, with no statistically significant difference. Conclusion: To detect recurrent or metastatic disease after surgical treatment in patients with differentiated thyroid carcinoma, US of the neck is a better screening modality as compared to the use of PET/CT. 목적: 분화갑상선암의 수술 후 재발 또는 전이의 평가에서 PET/CT와 초음파의 진단적 정확성을 비교하고자 한다. 대상과 방법: 분화갑상선암으로 진단을 받고 수술을 받은 후, 추적검사로 PET/CT와 초음파를 동시에 시행한 환자 128명에 대해 분석하였다. PET/CT와 초음파는 3개월 간격 내에 시행되었다. 미세침흡인검사나 수술을 시행하여 병리학적으로 전이 또는 재발을 확진하였다. 각 방법을 통계적으로 계산하고, 두 검사 방법의 진단적 정확도를 평가하였다. 결과: 128명의 환자 중 40명에서 수술 또는 미세침흡인검사를 통해 전이 또는 재발을 확진되었다. 31명의 환자에서 초음파와 PET/CT 모두에서 악성으로 판독되었다. PET/CT에서 FDG 흡수가 없거나 많지 않아 재발이 없는 것으로 판독된 8명의 환자는 초음파에서 악성 소견을 보였고, 병리학적으로 악성으로 확진되었다. 한 명의 재발 환자는 PET/CT에서 높은 표준화 섭취 계수로 재발 소견을 보였지만, 초음파에서 병변을 발견할 수 없었다. 초음파의 민감도, 특이도, 양성예측도, 음성예측도, 그리고 정확도는 97%, 85%, 75%, 99%, 그리고 89%였으며, PET/CT는 80%, 82%, 68%, 90%, 그리고 82%이었다. 전반적으로 초음파가 PET/CT에 비해 나은 결과를 보였으나, 통계적으로 유의한 차이는 보이지 않았다. 결론: 통계적으로 유의하지는 않으나, 목 초음파는 분화갑상선암의 수술 후 재발이나 전이를 발견하는데 더 유용한 검사법으로 생각된다.
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김재환,김상우,조원모,강희설,조영무,Kim, Jae-Hwan,Kim, Sang-Woo,Cho, Won-Mo,Kang, Hee-Seol,Cho, Young-Moo 한국축산환경학회 1996 축산시설환경학회지 Vol.2 No.2
The objective of this study was to estimate the investment limit in equipment capital by Capital Recovery Method. The data used was collected from 23 Hanwoo(Korean Native Cattle) farms in 1994. The necessary time for herd size expansion was average 5 years from opening(9.7 heads) to 50 heads, 4 years from 50 to 100heads, 3 years from 100 to 150 heads, and 2 years from 150 to 200 heads, respectively. It took 14 years from opening to 200 heads of herd size. The debts for fattening cattle farms were 15.2million won for the size of 50 heads, 37.1 million won for the size of 100 heads and 89.0 million won for the size 200 heads, respectively. Average rates of debt interest were 5.1 % 7.2 and 10.8, correspendingly. As the hear size increased, debt interest rates also increased due to government funds limit. The investment limits in equipment capital perfarm household were 77.7 million won for 50 heads, 135.1 for 100 heads, and 294.3 for 200 heads for 5,500 won per kg liveweight, 70.7 million won for 50 heads, 122.6 for 100 heads and 269.3 for 200 heads for 5,000 won per kg liveweight, 63.6 million won for 50 heads 110.0 for 100 heads and 244.2 for 200 heads for 4,500 won per kg liveweight.
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An orthodontic approach for Class III malocclusion in a pediatric cancer patient: A case report
김재환,지명관 조선대학교 치의학연구원 2019 口腔生物學硏究 Vol.43 No.1
Leukemia is a cancer that arises in the hematopoietic system, and the most common leukemia in children is the acute lymphoid leukemia (ALL). However, modern advances in therapeutic approaches have greatly increased the chances of survival. As the number of survivors of childhood cancer increases, more patients with cancer history seek orthodontic treatment. Certain dental conditions may require modifications to general orthodontic care in order to reduce or prevent adverse treatment outcomes in patients with histories of cancer, but orthodontic training courses do not often cover these specific aspects. The objective of this case report was to discuss the complications of chemotherapy related to dental development and document the outcomes of a first-phase orthodontic treatment of Class III malocclusion in a pediatric patient with a history of ALL.
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김재환,박노운,권영항,임종환,배장훈,엄기동 한국임상수의학회 2014 한국임상수의학회지 Vol.31 No.5
A 7-year-old, male Alaskan malamute was referred for a routine dental management. On the physicalexamination, the right hindlimb ataxia with a mild delay in proprioception was noted. On magnetic resonance images,an extradural ventral cystic structure compressing the spinal cord was found at the level between the first and secondlumbar vertebra. The cyst showed hypointense on a T1-weighted image with rim enhancement and hyperintense ona T2-weighted image. The cystic lesion was removed through right-side hemilaminectomy. In the histopathologicalexamination, evenly distributed fibroblasts and collagenous stroma with several cartilaginous materials were seen. Theneurological signs of the right hindlimb were successfully recovered within a week in follow-up neurologicalexamination and showed normal gait at 6 months after surgery.
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