경춘선 숲길 이용 만족도에 영향을 미치는 요인 분석 연구 - 공원의 안전성, 접근성, 쾌적성 중심으로 -

박세연(Park, Se-Yeon),황성은(Hwang, Sung Eun),최병윤(Choi, Byeong-Yun),강부성(Kang, Boo-Seong) 대한건축학회 2023 대한건축학회 학술발표대회 논문집 Vol.43 No.2

The purpose of this study was to analyze the factors affecting satisfaction of the park by selecting Gyeongchun Line Forest Park as the target site to relieve the inconvenience of people using a park. As the number of park users increased after COVID-19, complaints about using the park also increased. Through the survery the factors affecting satisfaction were identified by dividing them into categories of saftey, accessibility, and comfort and do an on-site investigation. In order to increase the safisfaction of the park, lighting and visual connection were important in terms of saftey, accessibility and guidance width and movement speed were importatnt in comfort.

도시근린공원 방범설계 (CPTED)의 효과성 검증

홍소연(Hong, So Yeon),권순호(Kwon, Soom Ho),박세희(Park, Se Hee),김은기(Kim, Eun Kee) 한국공안행정학회 2020 한국공안행정학회보 Vol.29 No.1

이 연구는 도시근린공원에서의 범죄예방환경설계 효과성 검증을 목적으로 실시되었다. 연구목적 달성을 위해 선행연구에서 활용된 범죄예방환경설계 평가항목을 활용하여 대상 공원 두 곳의 범죄예방환경설계 수준을 객관적으로 평가하였고, 설계 수준이 우수한 공원과 낮은 공원 방문객들을 대상으로 각각 범죄피해두려움을 측정하였다. 분석결과 설계 수준이 우수한 공원보다 설계 수준이 낮은 공원에서 방문객들의 범죄피해두려움이 더 높게 나타남을 확인 할 수 있었으며, 두 공원에서 느끼는 범죄피해두려움의 평균차이는 통계적으로 유의한 차이로 확인되었다. 따라서 도시근린공원에서의 범죄예방환경설계는 이용객들의 범죄피해 두려움을 낮추는 효과가 있다고 할 수 있다. 그러나 이 연구는 범죄피해두려움에 영향을 미치는 다른 요인들을 통제하지 못하였다는 점, 조사대상 공원의 범죄예방환경설계 수준에 대한 평가의 정교성이 다소 낮다는 점 등의 한계가 존재한다. 그럼에도 불구하고 ‘CPTED 인식’과 범죄피해두려움의 관계를 주로 검토하여 효과성을 검증하고자 한 기존 선행연구와는 달리 객관적 평가척도를 활용하여 설계수준 차이에 따른 범죄피해 두려움의 차이를 검증함으로써 CPTED의 효과성을 검증하였다는 점에서 의의가 있는 연구라 하겠다. This study was conducted to verify the effectiveness of crime prevention environment design in urban neighborhood parks. To achieve the objectives of the research, the crime prevention environmental design evaluation items used in the previous studies were objectively evaluated, and the crime prevention environment design levels of two target parks were objectively evaluated. Fear of crime was measured. As a result, visitors were found to have higher fears of crime victimization in parks with lower design level than those with better design level, and the average difference between crime fears felt between two parks was statistically significant. Therefore, the design of crime prevention environment in urban neighborhood parks can be said to reduce the fear of crime victims. However, this study has limitations such as the lack of control of other factors affecting the fear of crime, and the low level of elaboration of the assessment of crime prevention environment design of the park under investigation. Nevertheless, unlike previous studies that mainly examined the relationship between CPTED awareness and fear of crime, CPTED by verifying the difference of crime damage fear according to the design level by using objective evaluation scale. It is a meaningful study in that it verified the effectiveness of.

UV/H2O2 광산화공정을 적용한 원전 발생 방사성 폐액내 세제 처리

박은정,이지훈,박세문 대구대학교 환경기술연구소 2004 미래환경기술 Vol.1 No.1

원전 발생 방사성 폐액 내 세제를 제거하기 위한 전처리 공정으로 UV 광산화 공정을 활용하기 위하여 공정의 효율 및 적용 가능성에 대한 기초 실험을 수행하였다. 최적 처리조건을 도출하고자, 방사성 폐액의 평균 세제 함유량 (TOC 50∼100ppm)을 기준으로 모의폐액을 제조하여 과산화수소 주입량에 따른 세제 제거율, pH 변화에 따른 세제 제거율, 공기 공급량에 따른 세제 제거율을 도출하였다. 실험결과로서 과산화수소 주입량은 1000ppm, pH는 9.5일 때 최적 분해율을 보였고 공기 공급량의 영향은 받지 않는 것으로 밝혀졌다. 광분해 특성 규명을 위한 회분식 광분해 실험 결과, 광분해 반응 차수는 2차 반응임을 알 수 있었다. To apply the UV-photo oxidation process for the removal of detergent contained in the radwaste generated from the NPP, the effectiveness and feasibility were studied through the fundamental experiments. The simulants with TOC 50∼100ppm made of detergent were used for the lab-test. The optimum detergent removal rates due to the hydrogen peroxide volume, pH and air injection volume were investigated. The detergent removal rate was optimum at 1000ppm of hydrogen peroxide volume and at pH 9.5, while the air injection volume was not that much effective. The experimental result showed that the photo-oxidation degradation under the batch mode was of the second reaction.

정신분열병과 Neuregulin 1 유전자의 연합연구

박동연,이유상,조은영,조승희,장용이,전현옥,장수연,윤세창,김종원,홍경수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The authors recently found a suggestive evidence of linkage of chromosome 8p21-12 to schizophrenia in Korean multiplex families. Neuregutin 1 (NRGI) was identified in this locus as a positional and functional candidate gene for Schizo-phrenia, through several independent studies with European and Chinese populations. The purpose of this study is to determine whether NRGl is associated with schizophrenia in Korean population. Methods : Three SNPs (SNP8NRG221533, SNP8NRG241930, SNP8NRG243177) and two microsatellites markers (478B14-848,420M9-1395) located at the 5' end of NRGI were genotyped for 242 unrelated schizophrenia patients and the same num-ber of normal controls. Genetic association was tested by χ²-test (df=1). Not only for the whole patients group but also for asubgroup of patients with auditory hallucination. This subtype showed stronger linkage with chromosome 8p12 in the prior study of the authors with multiplex families. Results : G allele of SNP8NRG241930 was significantly in excess in the subgroup of patients with auditory hallucination compared to the control group (p=0.03, 0R=1.76). We also found that 3 SNPs haplotype TTC (p=0.04, 0R=0.58) and five markers haplotype TTC53 (p=0.01,0R=0.49) were associated with schziophrenia with a protective effect. Three SNPs haplotype CGT which is a part of the at-risk haplotype of the Icelandic schizophrenia families was found in excess in the patients group but no significant association was observed. Conclusion : NRGI might either play a mle in the predisposition to schizophrenia or be in linkage disequilibrium with a causal locus of this illness.

출아효모에서 TAR 클론닝법을 이용한 고등동물의 게놈으로부터 특정 염색체 부위의 분리

박정은,윤영호,이윤주,김광섭,윤세련,안태진,임선희,선우양일 동아대학교 기초과학연구소 2003 基礎科學硏究論文集 Vol.20 No.1

복잡한 게놈 분석에 용이하도록 효모의 인공 염색체(YAC) 클론닝 시스템은 발달되어왔다. YAC은 박테리아의 인공 염색체(BAC)보다 더 큰 단편을 클론닝할 수 있고, 또한 클론된 단편을 쉽게 변형시킬 수 있다. 형질전환과 연계된 재조합법(Transformation-Associated Recombination; TAR)은 게놈 라이브러리를 만들지 않고 직접 게놈 DNA로부터 분리하고자 하는 유전자나 특정 염색체 부분을 클론닝 할 수 있는 방법이다. 이 방법은 spheroplast transformation을 수행하는 동안, 목적으로 하는 유전자의 5' 그리고 3' 염기 배열(hooks)을 지닌 TAR 벡터와 게놈 DNA 사이에서 일어나는 상동성 재조합에 의해 이루어진다. 효모 내의 in vivo 재조합을 이용한 TAR 클론닝법은 복잡한 게놈으로부터 목적의 염색체 부분을 원형 YAC의 형태로서 선택적으로 분리할 수 있다. 그러므로 TAR 클론닝 법은 특정 염색체로부터 YACs을 만드는데 매우 유용하여, 전체 게놈으로부터 특이적 유전자나 유전자의 family를 분리하는데 효과적인 방법으로 사료된다. Yeast artificial chromosome (YAC) cloning systems have advanced the analysis of complex genomes considerably. They permit the cloning of larger fragments than do bacterial artificial chromosome systems, and the cloned material is more easily modified. Transformation-associated recombination (TAR) is a cloning technique that allows specific chromosomal regions or genes to be isolated directly from genomic DNA without prior construction of a genomic library. This technique involves homologous recombination during spheroplast transformation between genomic DNA and a TAR vector that has 5' and 3' gene targeting sequences (hooks). Using in vivo recombination in yeast, TAR cloning selectively isolates, as circular YACs, desired chromosome segments or entire genes from complex genomes. We propose that TAR cloning can provide an efficient means for generating YACs from specific chromosomes and that TAR cloning may be useful for isolating families of genes and specific genes from total genome DNA.

근관세정 방법에 따른 수산화칼슘 제재의 제거 효율 비교

은재승,박세희,조경모,김진우 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.6

The purposes of this study were to compare the efficacy of irrigation systems by removing a calcium hydroxide (Ca(OH)₂) paste from the apical third of the root canal and the effect of the patency file. Sixty single rooted human teeth were used in this study. The canals were instrumented by a crown-down manner with .04 taper ProFile to ISO #35. Ca(OH)₂ and distilled water were mixed and placed inside the root canals. The teeth were divided into 6 groups according to the root canal irrigation system and the use of patency file as follows: group 1 - conventional method: group 2 - EndoActivator : group 3 - EndoVac; group 4 - conventional method, patency: group 4 - EndoActivator, patency; group 6 - EndoVac, patency. All teeth were irrigated with sodium hypochlorite. After the root canal irrigation, the teeth were split in bucco-lingual aspect. Percentage of the root canal surface coverage with residual Ca(OH)₂ until 3 mm from working length was analyzed using Image Pro Plus ver. 4.0. Statistical analysis was performed using the One-way ANOVA, t-test and Scheffe's post-hoc test. Conventional groups had significantly more Ca(OH)₂ debris than EndoActivator, EndoVac groups. There was no significant difference between EndoActivator, and EndoVac groups. Groups with patency file showed more effective in removing Ca(OH)₂ paste than no patency groups. but. it was no significant difference. This study showed that EndoActivator and EndoVac systems were more effective in removing Ca(OH)₂ paste from the apical third of the root canal than conventional method. 이 실험의 목적은 근관 내에 충전된 수산화칼슘의 제거 시 치근단 1/3에서 기존의 근관세정법과 EndoActivator, EndoVac system의 세정 효율을 비교하고, 근관 세정 중 치근단공 개방 확인의 영향에 대해 평가하고자 함이다. 60개의 단근치를 사용하였고 ISO #35까지 근관성형 후 수산화칼슘을 충전하였다. 근관 세정법과 치근단공 개방 확인 유무에 따라 6개 실험군으로 나누어 세정하였다. 실험 치아를 양분하여 치근단 3 mm에서 근관 면적에 대한 잔존 수산화칼슘 면적의 백분율을 측정하였다. 실험결과 EndoActivator, EndoVac군이 기존의 근관 세정법 군에 비해 유의하게 높은 제거효율을 나타냈으며 (p<0.05), 치근단공 개방 확인 유무에 따른 유의한 차이는 나타나지 않았다. 이 실험 결과에 따르면 기존의 근관세정법으로 효과적인 세정이 불가능했던 근관의 치근단 1/3부위에서 EndoActivator, EndoVac system과 같은 근관 세정법이 효과적인 대안이 될 수 있다는 결론을 얻었다.

임상증례중심 성인 전문적 심장구조술 교육과정에 대한 고찰

유은영,박승현,박규남,최세민,김세경 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: To describe the first experience of case-based advanced cardiac life support(ACLS) course in Korea. Methods: We have given case-based ACLS course to 13 nurses(6 emergency nurses, 4 coronary care unit nurses, 3 professors) and 17 physicians(4 emergency physicians, 12 emergency residents, 1 intern). We performed the case-based ACLS course according to 1992 American Heart Association guidelines and recommendations for advanced cardiac life support by american ACLS instructors(1 pulmonologist, 4 critical care nurses). We performed final theoretical written test and 2 times written survey (immediate and 100th day after the course) about the course. Results: On final written test, all practitioners answered at least 70% of the questions correctly. There was no significant difference between nurses and physicians(86.2±3.6 of physicians and 82.5±6.8 of nurses, p=0.06). 90% of participants considered that case-based advanced cardiac life support was acceptable. 100th day after the course, 93% of participants answered that ACLS course have been helpful on his/her job and also want retraining of ACLS course. 70% of participants considered that ideal ACLS training committee in Korea is the Korean Society of Emergency Medicine. Conclusion: Case-based ACLS course is a useful educational method for physicians and nurses in Korea. In the future, we should organize Korean resuscitation committee and then make guidelines for ACLS, and then continuously educate physicians and nurses.

鋼 熔着金屬의 熱變形脆化에 關한 硏究

鄭世喜,金台永,林載奎,鄭熙敦,朴昌彦 全北大學校 1984 論文集 Vol.26 No.-

The susceptibility of weld metal(AWS, F76-EH14) on hot straining embrittlement has been examined. The sharp notch was machined on the weld metal of 1st bead and on coarse-grained HAZ transformed by next pass. After machining the notch, these specimens were bended at 250℃ to receive the hot straining embrittlement and they were done COD fracture toughness test by the three point bending, and then the change of plastic zone at notch tip was evaluated by microhardness test. The obtained results are summarized as follows. 1. Fracture toughness of weld metal was greater than that of base metal. 2. Fracture toughness of the coarse-grained HAZ was similar to that of weld metal. 3. Hardness of weld metal reheated by next pass was lower than that of weld metal owing to the effect of heat treatment. 4. Plastic deformation of the coarse-grained HAZ was less than that of weld metal.

치매방지 작업기구 사용이 항산화효소 활성에 미치는 영향

조경혜,박정은,윤지윤,문세보,박효영,정인옥,이정원 서울여자대학교 자연과학연구소 2001 자연과학연구논문집 Vol.13 No.-

We developed an occupational therapy tool to maintain and improve the cognitive function for the elderly who have senile dementia. 86 elderly people took a mininal mental state examination (MMSE) for the therapy to perform the occupational therapy, and divided into three groups based on avarage ages and MMSE values. The occupational therapy was treated three times per week for 10 weeks. The results showed that there were significant differences in the performing scores before and after the treatment ; the scores for the occupational therapy were increased significantly (p<0.001) and the performing time was shortened from 6-week throughout 10-week regimen. This study was to examine the effect on the activity of antioxidant enzymes by occupational therapy. The activities of antioxidant enzymes such as catalase, Glutathion-6-phosphate dehydrogenase (G6PDH), and superoxide dismutase (SOD) were increased to the normal standard by the occupational therapy for the elderly having dementia. The recovery of activities of antioxidant enzymes was obvious in severe demented elderly compared to those in normal or mild demented elderly. These results suggest that the occupational therapy had an beneficial effect on the protection against the oxidative stress especially for severe demented elderly, and the occupational tool need to be modified so as to improve the protection against the oxidative stress for normal and/or mild demented elderly.

아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.