응급실에 내원한 환자에서 어지럼증의 원인과 임상양상의 분석

문원식,정경운,위준선,문정미,전병조,김용권,소정일,류진호,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: Recently, The number of patients who have been complaining of the vertigo or dizziness has been increasing due to rapid growth of elderly population and senile disease. The differentiation of dizzy patients is not familiar to most emergency physicians. This study was designed to differentiate true vertigo and to investigate the clinical difference among central vertigo, peripheral vertigo, and other causes of dizziness. Methods: The authors analyzed the cases of 237 dizzy patients who visited the emergency department of Chonnam University Hospital during the recent 2 years. For the base of dizziness, associated past illnesses, severity, nystagmus type, and the causes of central and peripheral vertigo. Results: Female patients were 142(59.9%) and male patients were 95(40.1%). The most common age group was the 6th decade. The origin of dizziness was classified as peripheral cause(25.3%), central cause(32.9%), and others(41.8%). As to nature of the dizziness, the rotatory sense was dominant in peripheral vertigo and the floating sense and blurred vision in central vertigo. Peripheral vertigo was triggered by position change of head and body, and central vertigo by the eye movement. Audiograms I showed that most patients with central vertigo had normal hearing, but 46.7% of thoswith peripheral vertigo had an abnormal hearing disturbance. Nystagmus was more prevalent in peripheral vertigo Conclusion: History taking and physical examination played an important role in the diagnosis of dizzy patients. An important part of the diagnosis of a dizzy patient could be to evaluate the peripheral origin, the central origin and others causes. Because central vertigo may be associated with a significant neurological pathology, spectral radiological studies, including MRI and CT, are mandatory to rule out a devastating brain lesion.

중학교 8학년 과학 「지구의 역사와 지각변동」 단원에서 정보통신기술(ICT) 활용 수업의 효과

정진우,문병찬,정재구,이미영 한국과학교육학회 2004 한국과학교육학회지 Vol.24 No.6

이 연구는 중학교 8학년 과학 '지구의 역사와 지각 변동' 단원에서 ICT 활용 수업 과정안을 개발ㆍ적용하여 ICT 활용 수업이 학생의 과학 탐구 능력과 과학에 관련된 정의적 특성에 미치는 효과를 알아보는 데 그 목적이 있다. 이 연구를 위해 충청남도에 소재한 D중학교 2학년 2개 학급을 선정하고 교수-학습 방법을 달리하여 약 6주간 수업하였다. 1개 학급은 실험집단으로 ICT수업 과정 안을 개발하여 ICT를 활용한 수업을 실시하였으며, 1개 학급은 통제집단으로 교과서 위주의 전통적 방법으로 수업 하였다. 학습을 하기 1주일 전에 두 집단을 대상으로 과학 탐구 능력과 과학에 관련된 정의적 특성에 대한 사전 검사를 실시하였으며, 수업이 끝난 뒤에 사후 검사를 실시하였다. 그 결과, ICT를 활용한 실험집단과 전통적 학습을 실시한 통제집단의 과학 탐구 능력 검사에서는 실험 집단에서 유의미한 차이가 나타났다. 또한, 과학에 관련된 정의적 특성에 대한 검사에서 실험집단에서 통계적으로 유의미한 차이가 나타나지는 않았지만, 3개의 과학에 관련된 특성 범위 중에서 흥미 범위에서는 통계적으로 유의미한 차이가 나타났다. 이는 ICT 활용 수업이 학생들의 과학에 관련된 정의적 특성에도 긍정적인 효과가 있음을 시사하는 것이다. The effects of learning using Information Communication Technology(ICT) on the students' scientific inquiry ability and science-related affective characteristics were analyzed in Earth History and Crust Movement units of science textbook for eighth graders. For this study, two classes of middle school second students in Chung-nam were selected and taught for six week under different teaching methods. One class is the test class taught with ICT applied teaching materials and the other class is the control class instructed by a conventional method. One week before the experiment, both classes were given tests on scientific inquiry ability and science-related affective characteristics, and they were tested again after the experiment. The results of scientific inquiry test showed statistically meaningful differences in the experimental class and the control class. The experimental class showed statistically meaningful difference in scientific inquiry test. Science-related affective characteristics test showed no statistically meaningful difference in the experimental class. Among three scientific science-related affective characteristics, especially the one fields of interests showed statistically meaningful differences which suggest that learning using ICT has a positive effect on the expanding of students' science-related affective characteristics.

외상 후 뇌 지방색전증 1예

문정미,소정일,김용권,류진호,허탁,서정진,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Post-traumatic fat embolism was first reported by Zenker in 1862, Von Bergmann reported the first clinical diagnosis of the fat embolism syndrome in 1873. Fat embolism has been associated with traumatic or non-traumatic disorders. Fat embolization after long bone trauma is probably common as a subclinical event. The diagnosis of fat embolism syndrome is based on the patient's history, is supported by clinical signs of pulmonary, cerebral, and cutaneous dysfunction, and is confirmed by the demonstration of arterial hypoxemia in the abscence of other disorders. Two different mechanisms cause fat to embolize: direct entry of deposit fat into the blood stream and agglutination of endogenous or exogenous plasma fat. MRI can detect a cerebral fat embolism with a higher sensitivity than cerebral CT. We report a case of post-traumatic cerebral fat embolism without pulmonary involvement, and we present a review of the literature. A 16-year girl had a traffic accident and pelvic bone fracture. Forty eight hours later severe trauma become stuporous without a focal neurological deficit. The patient received supportive therapy, and her condition improved throughout her hospital course. She was discharged with good condition after a 30-day hospital stay.

뇌졸중후 우울증

문석우,서정석,남범우,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

In recent years, depression is most commonly reported psychiatric condition after stroke, poststroke depression(PSD) has attracted world-wide interest. This review focuses on the major research themes that have emerged. Pooled data from studies, have wide variation in results is due to different criteria for patient selection, different evaluation methods, diagnostic criteria and poststroke intervals, conducted throughout the world have found prevalence rates for from 18% to 65%. The diagnosis of PSD is most appropriately based on a structured mental state exam and DSM-N criteria for depression due to stroke with major depressive-like episode or depressive features. Rarely, poststroke patients may also develop bipolar mood disorder. The treatment of PSD, single antidepressant showing efficacy and electroconvulsive theraphy(ECT) and behavioral therapies have also effective. The progression of recovery following stroke can be altered by treating depression, which has been shown to improve recovery in activities of daily living(ADL) and cognitive impairment and to decreased mortality. The mechanisms underlying the association of stroke and mood disorder are important areas for future investigation.

배회성 거미(Pardosa astrigera) 주안과 부안의 미세구조적 분석

정문진,임도선,문명진 韓國電子顯微鏡學會 2000 Applied microscopy Vol.30 No.1

배회성거미안 별늑대거미의 4쌍의 단안은 앞이마 부분 1열에 전중안, 전측안, 2열에 후중안, 그리고 두흉부의 3열에는 후측안이 각각 1쌍씩 위치하고 있었다. 전중안의 망막을 구성하는 시세포는 두 개의 신경돌기를 가진 전형적인 이극성 신경세포였으며, 나머지 단안인 전측안, 후중안, 후측안은 단극성 신경세포임이 확인되었다. 후중안과 후측안의 감간은 시세포 원형질막의 일부가 미세융모로 변형된 감간체로 되어 었였으며, 망막을 구성하는 시세포들은 하나의 감간 주위에 규칙적으로 색소세포 돌기가 분포하고 있었으나, 전중안과 전측안의 망막내에는 불규칙적으로 시세포와 색소세포들이 분포 하고 있었다. 반사층은 시세포의 감간과 intermediate segment 사이에서 위치하는 불연속적인 구조이며, 주안인 전중안을 제외한 나머지 눈에서 관찰되었다. 전중안과 전측안이 그리고 후중안과 후측안의 크기가 각각 비슷하였으며, 단안을 구성하는 각 구성물의 크기는 각막이 4쌍의 눈에서 모두 비슷하였고, 렌즈, 세포체, 감간은 전중안과 전측안, 후중안과 후측안이 각각 비슷하였으며, 초자체는 후중안이 가장 크고 이어서, 후측안, 전중안, 전측안의 순으로 관찰되었다. The wandering spider, Pardosa astrigera, had four pairs of ocelli that arranged in three rows on the cephalothorax. Along the anterior margin lay a pair of small anterior median (AM) eye flanked on each side by anterior lateral (AL) eye. Two large posterior median (PM) eye was situated on the clypeus behind the anterior row and still more posteriorly was a pair of posterior lateral (PL) eye. The visual cell of retina consisted of cell body, rhabdome, and intermediate segment. Bipolar neuron was found in anterior median eye (principal eye) and unipolar neuron in others (secondary eye). Rhabdome showed that arranged in PMeye and PLeye. But rhabdomes of AMeye and ALeye were irregular in retina. Except AMeye incontinuous tapetum found in ALeye, PMeye, PLeye. Anterior median eye was similar to anterior lateral eye in length and posterior median eye similar to posterior lateral eye. Component size of eye were similar to 4 pairs eye in cornea. Size of lens, cell body, and rhabdome was similar not only anterior median eye and anterior lateral eye but also posterior median eye and posterior lateral eye. Vitreous body was large posterior median eye than others.

모체 Thyroxine 투여가 태아알코올효과를 가진 흰쥐 대뇌겉질 및 해마에서 NPY함유 신경세포의 생후 발달에 미치는 영향

김복,박상기,박영란,김종중,문정석,김주수,문영민,현영식,천관영,정윤영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Background and Objectives: Maternal alcohol abuse is considered to be one of the most prominent cause of neurobiological malformations in the postnatal and adult life of the offspring. In this study, we investigated the effects of maternal alcohol drinking on the postnatal development of NPY-containing neuron, and, the influence of thyroxine treatment on the cerebral cortex and hippocampus of pups of alcohol abused mother. Materials and Method: Time-pregnant rats were divided into three groups. Alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day 6; control pair-fed group B was fed a liquid diet in dextrin replaced alcohol isocalorically: alcohol + T4 group C received 35 calories liquid alcohol diet and exogenous thyroxine subcutaneously. Results: Group C showed prominent NPY immunoreactivity in the cerebral cortex compared to group A and B at P7. In group C, NPY-containing neurons were widely distributed in the all layers of cerebral cortex after P14. Besides, numerical decrease of NPY-containing neuron as age increases was not found in group C. However, the decrease of NPY-containing neuron was clearly observed in group A compared to group C after P14. In hippocampus, group Band C were appeared similar patterns after P7. Additionally, in group C, NPY immunoreactivity was prominently appeared in CA2 and CA3 at P14 as compared to group B. Conclusions: The present results showed the increase of intensity and number of NPY-containing neurons in cerebral cortex and hippocampus of pups of exogenous T₄ supplemented alcohol-exposed dams as compared to control pair-fed and alcohol-exposed pups at P7. It presumably suggest that NPY-containing neurons might be regulated by the early postnatal growth stimulatory effect of the exogenously supplemented T₄. Therefore, the increase of NPY synthesis caused by maternal administration of exogenous thyroxine may ameliorate fetal alcohol effect, one of the ill effects as a result of the dysthyroid state following maternal alcohol abuse.

徘徊性거미(Pardosa astrigera L.Koch)의 視覺器 微細構造에 관한 硏究

文明珍,丁文鎭 단국대학교 1994 論文集 Vol.28 No.-

The Wolf spides, Padosa astrigera L.Koch, had four pairs of ocelli that arranged in three rows on the cephalothorax. Along the anterior margin lay a pair of small anterior median eye(AME) flanked on each side by anterior lateral eye(ALE). Two large posterior median eye(PME) was situated on the clypeus behind the anterior row and still more posteriorly was a pair of posterior lateral eye(PLE). The common structure of eyes consisted in cornea, lens, vitreous body, retina. Lens was composed of cuticular lamella and biconvex type. Vitreous body comprised simple columna cells. The visual cell of retina consisted of cell body, rhabdome, and intermediate segment. Bi-polar neuron (cell body was found at the level of the middle portion of visual cell) was found in anterior median eye and unipolar neuron(rhabdomere lay beneath the cell body) in others. Rhabdome showed that arranged in PME and PLE. But AME and ALE rhabdome were irregulary in retina. Except AME, incontinuous tapetum found in ALE, PME, PLE. Anterior median eye was similar to anterior lateral eye in length and posterior median eye similar to posterior lateral eye. COmponents size of composed eye was similar to 4 pairs eye in cornea. Size of lens, cell body, and rhabdome was similar not only anterior median eye and anterior lateral eye but also posterior median eye and posterior lateral eye. Vitreous body was large posterior median eye than others.

Cellulase 생산 야생효모의 선별 및 세포외 Cellulase 생산

문정수, 박경서, 김혜원, 김수진, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.33 No.1

비병원성 야생효모로부터 알칼리성 단백질분해효소 생산

문정수, 박경서, 공유리, 김수진, 이종수 배재대학교 자연과학연구소 2022 自然科學論文集 Vol.33 No.1

초음파 이송시스템의 진행파 제어에 관한 연구

정상화,신상문,김태호,서호진,박진완 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

Methods of major transport system used in many industry fields are conveyor belt, magnetic levitation system and indexing system. It is an indispensable device in many fields and especially it is very important in the factory automation. However, the conventional transport system can damage precision optical components by the contact force and destroy the inner structure of semiconductor by the magnetic field. The new transport system for transporting without damage is required and the ultrasonic wave transport system has been proposed to replace the conventional transport system. In this paper. the object transport system using the ultrasonic wave is developed. Traveling waves are generated through the use of the ultrasonic wave generator to two ends of the beam. The modelling equation on steady state response of ultrasonic vibration is expressed through normal mode expansion. Natural frequency of flexural beam is estimated. Transport direction of the object is analyzed according to phase difference and frequency. In addition, it is verified by experiment.