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보문 : 항고혈압성 안지오텐신 전환효소 저해제를 생산하는 새로운 효모의 선별 및 저해물질 최적 생산조건
강민구 ( Min Gu Kang ),김하근 ( Ha Kun Kim ),이성훈 ( Sung Hun Yi ),임성일 ( Sung Il Lim ),이종수 ( Jong Soo Lee ) 한국균학회 2011 韓國菌學會誌 Vol.39 No.3
Forty eight strains of yeast were cultured in potato dextorse(PD) broth at 30˚C for 24 hr and centrifuged with 12,000 rpm for 20 min. After concentrated the cultures, antihypertensive angiotensin I-converting enzyme(ACE) inhibitory activities of its concentrates were investigated. Among them, the concentrates from Saccharomyces cerevisiae Y183-3 showed the highest ACE inhibitory activity of 71.8%. The ACE inhibitor from Saccharomyces cerevisiae Y183-3 was maximally produced when Saccharomyces cerevisiae Y183-3 cultured in PD broth at 30˚C for 36 hr.
Sol-Gel방법에 의해서 성장시킨PbTiO₃박막의 결정화와 물리적 성질
구영진,강민진,정원태,김태현,김상수 昌原大學校 基礎科學硏究所 2000 基礎科學硏究所論文集 Vol.12 No.-
Ferroelectric PbTiO3 thin films coated on SiO2/Si(100) and ITO glass substrates were prepared by sol-gel processing of metal alkoxide solutions and solvents. The use of sol-gel method for preparing various functional films makes it possible for the homogeneous distribution of elements at the molecular level, precise composition control, lower temperature synthesis, large surface coating and high optical quality. First of all, the XRD investigation shows that perovskite phase of polycrystalline PbTiO3 was formed by four times coating of the concentrated solution and by the heat treatment over 500, 600℃(O2 gas and air) and over 10, 20, 30 min. Surfaces of thin films were crack-free and uniform and the average grain size investigated by SEM was 0.25∼1.00 ㎛. Dielectric constant of PbTiO3/ITO glass thin film were 380 ∼ 5.25 in the region of 1 kHz∼ 10 MHz at room temperature(30℃), respectively. From the hysteresis loop of PbTiO3/ITO glass thin film, a remnant polarization of 0.382 μC/cm2 and a coercive filed of 23.85 kV/cm were obtained. At the frequency(5 kHz), C-V measurements of films in MFIS and MFM configurations showed well-behaved C-V characteristics and an injection type hysteresis. The capacitance of flat band(CFB) was 60 pF. The band gap energies of the thin films depend on the assumption of direct or indirect transition. Using one layer structure model, we calculated refractive index, extinction coefficient, absorption coefficient and band gap energy of thin film in the wavelength range of 300 to 800 nm. The band gap energy, refractive index and extinction coefficient at λ = 6325 Å of the PbTiO3 thin film were 3.7 eV, 1.96 and 0.1 respectively.
강민구,배지훈,박경용,김갑일 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-
In this paper, a biped robot is designed and implemented, and walking tests are performed using a fast walking model. In order to embody the human joint structure, designed biped robot has each two degree of freedom attached to the pelvic, knee, and ankle . Using two motors for each knee makes it possible to have the same walking as human walking and fast walking. Also in joint controller, PID control algorithm may causes variation to the robot, which make the system unstable. Therefore, a PD controller is used to limit the vibrations as much as possible allowing steady state error to a certain extent.
지구성 및 파워선수에서의 안정시 혈청효소 분석 : An object on cyclists and weight lifters 사이클 및 역도선수를 대상으로
강신일,김민구 公州大學校스포츠科學硏究所 1999 스포츠科學硏究所論文集 Vol.- No.13
This study was performed to evaluate the changes on serum enzymes in resting state by regular, prolonged aerobic and power exercise. Subjects were consisted of 21 male and 11 female cyclists and 16 male and 13 female weight lifters. They were highly traininged state. (1) Serum glucoses and triglycerides showed values within normal limits but the glucose levels of weight lifters were lower than cyclists. (2) Serum AST and ALT also showed within normal values and male athletes values were larger than female athletes but no statistical significance. (3) Total CPK levels showed apparent difference between two type of exercise, weight lifters had higher CPK levels than cyclists, especially male athletes had statistical significance. The isoenzyme CPK-MM also showed higher values and had statistical significance in male and female athletes. (4) Total LDH was higher in weight lifters than cyclists and isoenzyme LDH-4 and LDH-5 had significant difference. (※) From the results, we could be suggested serum total CPK and isoenzyme LDH-4, and LDH-5 showed changes of physical adaptation by prolonged power exercise in resting state and they would be used indicator of exercise ability.
송민정,송혁,이태강,기노갑,박현구,김선우 대한건축학회 2004 대한건축학회논문집 Vol.20 No.5
The "Sound Classification System on Floor Impact Sound Insulation Performance" is being studied in Korea. For that study, vocabularies appropriate for evaluation and reporting are needed. In this study, adequate words for evaluating floor impact sound have been extracted by reviewing the existing vocabularies and augmenting this with the results of a questionnaire prepared especially for apartment dwellers. As a result of this study, followings are suggested. 1) The heavy impact sound sources are more highly ranked than light impact ones. And the louder sound sources are the more accumulated points. 2) Highly ranked vocabularies are different for each source. 3) Floor impact sound evaluating words such as ‘Annoying’, ‘Disagreeable’, ‘Strident’, ‘Disturbed’, and ‘Dissonant’ are highly ranked. ‘Annoying’ is the word most accurately expressing the subjects' unpleasant feeling of domestic floor impact noise. 4)‘Unpleasant’, ‘Noisy’, ‘Irritating’, ‘Annoying’ are main unpleasant factors to floor impact sounds occurring in our domestic apartment houses.
도둑놈의 갈고리로부터 생산된 항비만성 Lipase 저해제와 시판 Lipase 저해제의 활성 비교
이종국 ․ 강민구 ․ 이종수 배재대학교 자연과학연구소 2011 自然科學論文集 Vol.22 No.1
Obesity is the cause of various diseases including high blood pressure, diabetes, hyperlipidemia, and cerebrovascular accidents. Therefore, development of new anti-obesity nutraceuticals or drugs is necessary. In previous paper, we selected Desmodium oxyphyllum as a potent lipase inhibitor-containing herb. In this study lipase inhibitory activity of Desmodium oxyphyllum and commercial lipase inhibitor were determined and compared. Lipase inhibitory activity of extract from Desmodium oxyphyllum showed 67.4%, whereas commercial lipase inhibitor showed more high 85.3% rater than that of Desmodium oxyphyllum.
Cao-MgO-SiO₂-P₂O -CaF₂계 생체활성 결정화 유리의 기계적 성질에 미치는 ZrO₂및 Al₂O₃의 분산 강화 효과
박찬운,강건구,원대희,이민호,배태성 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.2
Bioactive glass-ceramics can form tight chemical bonds with bone, however, their poor mechanical properties may limit their clinical applications. Alumina ceramics show good biocompatibility and high strength but can't form chemical bonds with bone. Hydroxyapatite ceramics and bioglass form chemical bonds with bone but their strength and fracture are relatively low. Glass ceramics containing apatite and wollastonite crystals can form tight chemical bonds with bone and show relatively high strength and fracture toughness. Bioactive glass-ceramics toughened by alumina and tetragonal zirconia polycrystals show relatively high mechanical strength. Both bioactive and high strength ceramics will be widely applicable to many clinical applications. In this study, bioactive glass-ceramics toughened by alumina and zirconia polycrystals were fabricated, and crystallization behavior, biaxial flexure strength, fracture toughness, and bioactivity were measured. The results obtained were summarized as follows; 1. The major crystaline phase in the matrix glass were observed to be apatite, wollastonite, and β-TCP. 2. Biaxial flexure strength and fracture toughness values were more improved by the dispersion toughening of alumina and zirconia, and the improvement of mechanical strength was more higher in the dispersion toughening of zirconia than that of alumina. 3. The bioactivity, which was evaluted from apatite formation in the simulated body fluid, was higher in the dispersion toughening of Zr-O₂than that of Al₂O₃.
소선섭,강민구,김영은,조미순 公州大學校 基礎科學硏究所 2003 自然科學硏究 Vol.10 No.-
본 논문은 Kazuo Ukaji와 Katsumi Tamaki의 논문 중 회전속도(回轉速度)와 표류각속도(漂流角速度)의 관계를 기초로 하였다. 그들에 따르면, 회전삼중수조 실험값이 수치모델값보다 열손실에 의해 약 10% 정도 작고, Ω(회전속도)값이 증가하면 ω(표류각속도)는 점차적으로 감소함을 알 수 있었다. 본 논문에서는 그것을 실험으로써 증명하고자 하였다. 온도차(∆T)를 일정하게 유지하고 회전속도를 증가시키면서 파를 관찰하였다. 그 결과, 회전속도(回轉速度)를 크게 할수록 파의 표류각속도는 점차 감소하는 경향을 나타냈다. 또 회전속도에 따른 표류각속도의 기울기는 온도차가 작은 경우에 기울기가 더 높게 나타났다. This essay was based on relation of the drift angular speed and angular velocity in the essay of Kazuo Ukaji and Katsumi Tamaki. According to them, because of heat loss, rotating fluid annulus experimental value is lower about 10 percent than numerical model value, we could know that ω is dwindling if Ω increases. In this essay, we observed to certify it as an experiment. We kept differences of temperature changelessly, and observed form of waves as increasing turning number of times. By the result, when we changed greatly volutions per minute, observed hat the drift angular speed of wave is dwindling. Also, by the result, we observed tilt of a drift angular speed by angular velocity, slant in case difference of temperature is low.