Calcium Carbonate와 fibrin adhesive의 병용이 성견 2급 치근분지부 치주조직 재생에 미치는 영향

서은표,정현주,김영준 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

The purpose of this study was to evaluate the effect of combined use of fibrin tissue adhesive and porous resorbable calcium carbonate on the periodontal regeneration of the class Ⅱ furcation defects in dogs. Class Ⅱ furcation defect was surgically created on the second, third, and fourth premolars bilaterally in the mandibles of six mongrel dogs. The experimental sites were divided into four groups according to the treatment modalities: Control-surgical debridement only; GroupⅠ-calcium carbonate grafting; Group Ⅱ-application of fibrin adhesive only; Group Ⅲ-application of fibrin adhesive after calcium carbonate grafting. The animals were sacrificed at 2, 4, and 12 weeks after periodontal surgery and the decalcified specimens were prepared for histologic and histometric examination. The results are as follows : Clinically, there were no inflammatory response in all groups after 2, 4, and 12 weeks. In the Control group, junctional epithelium migrated apically to the reference notch. In Group Ⅰ, graft materials exfoliated from the defect throughout the experimental periods and new bone was seen in the notch area at 4 and 12 weeks' specimens. At 2 weeks, fibrin adhesive was indistinguishable in Group Ⅱ. In Group Ⅲ, the graft material was maintained in the defect throughout the experimental periods and the amount of periodontal tissue regeneration was greater than other groups. These results suggest that the use of fibrin tissue adhesive in conjunction with porous resorbable calcium carbonate would improve the stability of graft material and inhibit the epithelial downgrowth and contribute to periodontal regeneration.

교잡종 찰옥수수에 대한 연구 III : Ⅲ. 국내 옥수수 유전자원 수집종에 대한 주요 특성 분포

서정은,주현민,최윤표,홍범용,조양희,주정일,지희정,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

2006년 국내 각 지역으로부터 수집된 재래종옥수수 유전자원을 관행방법에 의해 파종하고 주요특성별로 분포도를 살펴본 결과는 다음과 같다. 1. 수집된 유전자원에 대한 발아율은 대부분 80∼100%이상의 분포를 보였으나, 일부 수집계통에는 30% 미만의 극히 저조한 발아율을 보였다. 2. 수집자원에 대한 초기생육을 살펴보면 극히 생육이 저조한 것이 40% 정도를 보였고, 극히 우수한 자원은 3%미만으로 나타났다. 3. 간장은 대부분이 150∼199cm범위에 55%가 분포하고 있었으나, l00cm이하가 5%, 250cm이상이 8%로 나타나 수집종간에 큰 차이를 보였다. 4. 주당 분얼수는 1개 미만이 40%의 분포를 보였으나, 일부 수집종에서 2 내지 3개의 분얼수를 보이는 계통이 확인되었다. 5. 개화소요일수는 61∼64일의 범위에서 40%, 57∼60일의 범위에서 30%의 분포를 보였으며, 특히 일부 수집종의 경우 55일 이하의 극조생종도 10% 정도의 분포를 보였다. 6. 이삭길이는 대부분 11∼15cm범위에 60%가 포함되어 있으나, 일부계통에서 5cm미만이 2%, 16∼20cm의 이삭길이도 10%가 분포하였다. Germination ratio on the 300 collected genetic resources showed 80 to 100 percentage, but those of some accessions were very low as below 30 percentage. Early growth phase of most of these lines were very poor while some collected lines were very vigor. Range of stem height showed from 150 to 199cm, but that of some accessions showed below 100cm as five percentage and some of them was over 250cm as eight percentage. Number of tillers per plant appeared less one but some collected lines have two to three tillers per plant. In days to tasseling, some accessions showed more four per plant. Ear length of these accession showed above 60 percentage as 11 to 15cm, while that of some collected lines showed over 10 percentage as 16 to 20cm.

한국형 우울장애 약물치료 알고리듬 2006 (Ⅰ)

서정석,민경준,김원,석정호,박원명,송해철,이상열,전덕인,전현태,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

Objectives : Since the publication of Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management for depressive disorder. We revised KMAP-MD to Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. This paper is one of the following 4 papers consisting of Korean pharmacological algorithm for depressive disorder. Methods : The questionnaire consisted of 4 parts ; initial treatment of 1) non-psychotic depressive disorder, 2) psychotic depressive disorder, 3) treatment strategy for clinical subtypes and drug choice considering adverse effects, and 4) treatment for depressive disorder in women. It was composed of 22 questions, and each question had 54 sub-items. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. We classified the expert opinion to 3 categories (the first-line, the second-line, or the third-line). Results : For non-psychotic major depression, regardless ofthe severity of an episode, the antidepressant (AD) monotherapy was the optimal first-line treatment. SSRI, venlafaxine, and mirtazapine were the 1st-line AD. In case of a partial or no response to initial strategy, adding another AD was recommended. For psychotic major depression, combination of an AD and an atypical antipsychotic (AAP) was the treatment of choice. Among AAPs, quetiapine, rispendone, olanzapine were preferred. For non-responder to initial strategy, the next step was adding or changing AD before changing AAP. For women with premenstrual dysphoric syndrome or postpartum depression without psychotic features, AD monotherapty was a preferred strategy while for psychotic postpartum depression, combination of AD and AAP was recommended. Experts recommended various ADs according to adverse effect. Conclusion : These results suggest that the medication strategies for depressive disorder are rapidly changing and reflect the recent studies and clinical experiences.

한국형 우울장애 약물치료 알고리듬 (Ⅳ) : 우울장애의 아형 및 부작용에 따른 항우울제의 선택과 여성우울장애에서의 치료전략

전현태,이상열,김원,민경준,박원명,서정석,석정호,송해철,전덕인,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : In 2002, the Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) was published, but there has been a need for a guideline about detailed issues of depressive disorder. We revised KMAP-MDD andreestablished Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. Methods : A questionnaire had been developed by the executive committee for KMAP-DD. The review committee consisted of 101 experienced psychiatrists. From the total of 22 questions in the questionnaire, 7 questions were evaluated for these subjects . We classified the expert opinions to 3 categories according to its confidence interval; first, second and third line. Results : SSRI and venlafaxine were the first line antidepressants (AD) for atypical and melancholic depression. For dysthymic disorder and minor depressive disorder, SSRI was recommended as the first line medications. Only AD medications was a preferred initial strategy for treating premenstrual dysphoric disorder, mild to moderate and severe non-psychotic postpartum depression. In severe psychotic postpartum depression, combination therapy of AD and atypical antipsychotics was the treatment of choice. SSRI was preferred when considering sedation, anticholinergic and cardiovascular adverse effects. Also, experts recommended mirtazapine against gastrointestinal adverse effects and bupropion in avoiding sexual dysfunction. Conclusion : These results suggest that clinicians have to consider both clinical situations and drug adverse effects in the choice of antidepressant medications.

한국형 우울장애 약물치료 알고리듬 2006 (Ⅲ) : 정신병적 양상을 동반한 주요우울삽화

김원,박원명,서정석,민경준,석정호,전덕인,전현태,이상열,송해철,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : Since the publication of Korean Medication Algorithm Project for Major DepressiveDisorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management of depressive disorder. We revised KMAP-MD 2002 and developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) 2006. Methods : We developed a questionniare for surveying the opinion of experts on pharmacotherapy of depressive disorder. The questionnaire consisted of 4 parts ; 1) treatment of non-psychotic depressive disorder, 2) treatment of psychotic de-pressive disorder, 3) treatment according to clinical subtypes and drugs choice considering adverse effects, and 4) treatment of depressive disorder in women. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. It is composed of 22 questions, and each question includes 54 sub-items. We classified the expert opinionto 3 categories (the first-line, the second-line, or the third-line) by χ²-test. Results : For depressive disorder with psychotic features, most reviewers prefer the combination of antidepressant and atypical antipsychotics. Electroconvulsive therapy and the combination of antidepressant and typical antipsychotics were the second-line treatment. Among antidepressants, venlafaxine was the most preferred, and SSRI and mirtazapine followed. Among atypical antipsychotics, quetiapine, risperidone and olanzapine were the most preferred, in this order. In patients who have no response to the first-line treatment, many reviewers recommended switching to another antidepressant or adding another atypical antipsychotics Conclusion : For severe depressive disorder with psychotic features, the combination of antidepressant and atypical antipsy-chotics was preferred for the first-line treatment. These results suggest that the medication strategies of depressive disorder are rapidly changing and reflects the recent studies and clinical experiences.

Spin-Peierls 전이를 하는 CuGeO₃계의 이온 치환 효과

이영배,채광표,권우현,백서욱,이성호 건국대학교 자연과학연구소 1998 建國自然科學硏究誌 Vol.9 No.1

Spin-Peierls 전이를 하는 CuGeO₃계에 원소를 치환했을 때의 자기적 및 결정학적 특성을 비교 검토하고, 직접 Cu₁-xGe₁-xFe₂O₃(x=0.05, 0.1) 시료를 제조하여 SQUID, Mssbauer 분광기, X-선 회절 방법으로 연구하였다. 이 시료의 결정구조는 orthorhombic 이고 격자 상수는 x= 0.05 때 a = 4.795Å, b=8.472Å, c=2.904Å 이고 x=0.1때는 a=4.784Å, b=8.472Å, c=2.904Å였다. 상온에서 Mssbauer 스펙트럼은 Fe³+ 이온의 사면체 자리에 의한 이중선과 팔면체 자리에 의한 Zeeman 선으로 중첩되어 나타났고 자기감수율의 극대점과 Mssbauer 변수의 불연속으로부터 본 시료의 spin-Peierls 전이 온도는 13K 임을 알아냈다. The magnetic and crystallograpic properties of the substituted spin-Peierls transition CuGeO₃ system have been reviewed, and we synthesized the Cu₁-xGe₁-xFe₂xO₃ (x=0.05 and x=0.1) system and studied by superconducting quantum interference device, Mossbauer spectrometer and x-ray diffractometer. The crystal structure is orthorhombic and the lattice constants are decreased as increasing iron contents. That is, in Cu₁-xGe₁-xFe₂xO₃ system a=4.795Å, b=8.472Å and c=2.932Å for x=0.05, and a=4.784Å, b=8.472Å and c=2.904Å for x=0.1 respectively. The Mossbauer spectra are superposition of the doublet due to the Fe³+ ions at tetrahedral sites and the sextet due to the Fe³+ ions at octahedral sites at room temperature. From the cusp of the magnetic susceptibility and the discontinuity of Mossbauer parameters we found the spin-Peierls transition temperature of our samples is 13K.

재래식 시장 지하 상인의 호흡기증상 및 폐기능 조사 연구

이승관,이창규,조경진,임현표,서장훈,최윤수 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

The prevalence of respiratory symptoms and pulmonary function were studied in a group of 55 whole-sale market merchants Working in underground. As a control group, 55 whitecollar workers was also included in this study. Following results were obtained. A higher complaint for respiratory symptoms(cough, sputum, chest tightness, shortness of breath) was found among merchants than control workers. The measurement value for FVC, FEV1.0, FEV 1.0% in the merchants were reveal to lower figure in comparison with control groups. The measurement Value for MVV, PEF in the merchants were lower than control groups, but was not significant statistically. The pattern of pulmonary ventilation disturbance in the whole-sale market merchant were the same as followings : restrictive disturbance(6 person), abstrictive disturbance(1 person), and combined disturbance(1 person).

Effect of nitric acid on wet etching behavior of Cu/Mo for TFT application

Seo, Bo-Hyun,Lee, Sang-Hyuk,Park, In-Sun,Seo, Jong Hyun,Choe, HeeHwan,Jeon, Jae-Hong,Hong, Mun-pyo Elsevier 2011 Current Applied Physics Vol.11 No.1

<P><B>Abstract</B></P><P>Recently, copper metallization has been widely developed in TFT-LCD industry, because of its lowest electrical resistivity compared to other metal candidates such as aluminum and molybdenum. In addition, the copper metallization becomes more significant issue in a high frequency driving TFT-LCD with large sized panel. Since the copper has a low adhesion force against the glass substrate, the copper is inevitably used with an aid of an adhesive metal layer such as Ti, Ta and Mo. When the dissimilar metals like the copper and molybdenum are exposed together in a wet etchant, a typical galvanic reaction occurs and this results in an undercutting of copper line or partial stains on the metal surface after drying. Especially, it is well-known that the suitable taper angle of Cu/Mo is difficult to obtain. Such failures often lead to a bad performance of thin film transistor and the display quality. Wet galvanic corrosion behavior of DC magnetron sputtered the double layers of Mo alloys and copper on the glass substrate has been examined. Compared with Cu/Mo–Ti system, the pure Mo/Cu system shows recessed galvanic corrosion behavior.</P>

A New Preparation Method of Pyridoxal Phosphate Enzyme Using Affinity column Chromatography

Hyun-Jung Cho(조현정),Kwang-Hwan Jhee(지광환),So-Hyun Yoon(윤소현),Kyo-Yeon Kim(김교연),Ji Hyun Seo(서지현),Il-Han Lee(이일한),Seung-Pyo Hong(홍승표),Moon-Hee Sung(성문희) 한국생물공학회 2004 한국생물공학회 학술대회 Vol.2004 No.10

Social Isolation, Loneliness and Their Relationships with Mental Health Status in South Korea

Myung Hyun Kim,Ji Hyun An,Hye Rin Lee,Seo Hyun Jeong,Soo Jin Hwang,Jin Pyo Hong 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.7

Objective This study aims to investigate the prevalence and psychological impact of social isolation and loneliness in South Korea. Loneliness and social isolation have been regarded as a risk to both physical and mental health. However, most studies have focused on the elderly; hence, there are limited studies on the characteristics of socially isolated or lonely people considering age. Methods A sample of 1,700 participants was selected from three major cities in South Korea. In-person interviews were conducted to evaluate loneliness, social isolation and mental health status. Results Among the participants, the prevalence of social isolation and loneliness was 17.8% and 4.1%, respectively. Males decreased the odds of loneliness (AOR 0.49, 95% CI=0.28-0.87), while increasing the odds of social isolation (AOR 1.44, 95% CI=1.12-1.86) after adjusting for age and sex. Greater depressive and social phobic symptoms were associated with increased odds of loneliness and social isolation. Conclusion Social isolation and loneliness are prevalent among Koreans and associated with depression, social phobic symptoms, and suicidality. This study provides a foundation for further research to investigate nationwide prevalence and a more in-depth analysis of loneliness and social isolation.