SD Rats를 이용 1-hexene의 흡입독성 연구

김현영,임철홍,정용현,이권섭,이성배,이준연,한정희,전윤석,이용묵 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

The purpose of this study was to investigate the acute (4 hours) and repeated-dose (6 hours a day, 5 days a week, 4 weeks) toxic effects of I -hexene on Sprague- Dawley (SD) rats which were treated by inhalation. The results were as follows; I. The median lethal concentration (LC_(50)) was estimated 52,694 ppm (confidence limit 95%; 49,494~55,447 ppm) in acute inhalation. Abnormal clinical signs related to the l-Hexene were not observed with the acute inhalation dose. Gross findings of necropsy revealed on evidence of specific toxicity related to the 1-hexene, II. By repeated inhalation exposure the body weight of male were more or less reduced by the dose of 2,500 ppm and 5,000 ppm compared with control group. However there were no significant variation hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-hexene were not shown. In conclusion when we exposed I-hexene to SD rats for 4 weeks, 5 days per week, 6 hours per day, the Lowest observed effect level (LOEL) was over 2,500 ppm and Non observed effect level (NOEL) was below 500 ppm.

무도 전공 학과별 취업인식 조사 : 용인대학교 무도대학 소속 학과를 중심으로

이병익,강성철,김도준,박준석,김주연 용인대학교 2011 용인대학교 논문집 Vol.29 No.-

The aim of this survey is employment perception of martial arts major students in yongin university. The university education has various objects, one of the most important purpose is opportunities for employment. As time have changed, martial arts major students pointed out that their needs for employment. If universities accept their needs, it can be raise competitiveness of martial arts major departments in the academic world. This research is released its earnings report, the data will have significant meanings for the martial arts major departments sector grappling with traditional understanding. Therefore a realistic employment measure is urgently needed for martial arts major students, because it will need to be tailored to fit into the realities and by the limitations of martial arts major's departments curriculum. The research found the martial arts major students's cognitions on employment planning of individualized department education, employment education management of martial arts major departments and martial arts education system from university to society through questionnaires. From this point of view, this research was based on students who belonging to the college of martial arts(judo, taekwondo, combative martial arts, oriental martial arts, security service) in yongin university.

만정 뇌경막하혈종에서 술전 CT음영 및 천두폐쇄배액술후 배액량과 재발과의 상관관계에 대한 연구

임동준,박윤관,정용구,김봉룡,정흥섭,이기찬,이훈갑,서중근 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.10

척수원추내에 발생하여 외장성 성장을 보인 낭종성 기형종 -증 례 보 고-

임동준,박윤관,김애리,정흥섭,이기찬,이훈갑,서중근 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.10

연하장애를 보이는 뇌졸중환자에서 경관 유동식 종류에 따른 혈액학적 지표 변화 연구

오준호,신성헌,이윤정,강윤주,김용균 관동대학교 의과학연구소 2006 關東醫大學術誌 Vol.10 No.1

상악 유전치부의 치간공간과 인접면 우식에 관한 조사연구

김진영,이광희,라지영,안소연,정승열,임경욱,반재혁 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

본 연구는 상악 유전치부의 치간공간과 인접면 우식의 상관관계를 평가해보고자 하였다. 익산에 거주하는 만3-7세의 어린이 555명을 대상으로 하였으며 탐침이 통과하는지 여부로 치간공간이 있음과 없음으로 분류하였고 와동이 형성되었거나 법랑질 표면이 연화되었을 경우 인접면 우식이 존재하는 것으로 판단하였다. 연구 결과 다음과 같은 결론을 얻었다. 1. 상악 유전치부의 치간공간은 영장류 공간이 77.4%, 발육공간이 유측절치와 유중절치 사이에서 54.4%, 양유중절치 사이에서 39.0%로 나타났다. 2. 인접면 우식발생율은 우측유견치가 6.3%, 우측유측절치가 14.7%, 우측유중절치가 33.5%, 좌측유중절치가 33.7%, 좌측유측절치가 16.0%, 좌측유견치가 4.7%로 나타났다. 3. 치간공간의 수가 많을수록 상악 유전치의 우식발생율은 낮아졌으나 그 상관관계(r=0.024)는 미약하였다. 4. 상악 유전치부에 공간이 존재하지 않을 경우 존재할 때 보다 평균 우식발생율이 높았으며, 치간공간이 전혀 존재하지 않는 경우 한 곳이라도 치간공간이 존재하는 경우보다 평균 우식발생율이 2배 이상 높은 것으로 나타났다. The purpose of this study was to assess the relationship between interdental spaces and proximal caries in maxillary anterior primary teeth. 555 children aged 3-7 inhabit in Iksan were divided into two groups, depending on the presence of interdental space which was detected by a dental explorer. They were determined to have proximal caries if cavity was formed or the enamel surface was softened. The results were as follows : 1. Regarding interdental spaces, 77.4% had primate spaces; 54.4% had developmental spaces between central and lateral incisor, and 39.0% between central incisors. 2. Interproximal caries incidences in right primary canine, lateral incisor, and central incisor were 6.3%, 14.7%, and 33.5%, respectively. Also interproximal caries incidences in left primary central incisor, lateral incisor, and canine were 33.7%, 16.0%, and 4.7%, respectively. 3. Children with more interdental spaces had less caries incidence, but the relationship was weak(r=-0.024). 4. The mean caries incidence was higher in absence of interdental space of maxillary primary incisors than in presence of space. The mean caries incidence with no interdental space was twice as high as that with presence of interdental space.

Actazolamide와 Fluphenazine의 뇌척수액 생성에 대한 효과

송준혁,박윤관,정흥섭,서중근,이훈갑,이기찬,주정화 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.10

The purpose of this study was to investigate the effect of acetazolamide and fluphenazine on the formation of CSF. Studies were performed in 12 cats those were divided into 2 groups ; A-F group included animals received initial acetazolamide infusion and additional infusion of fluphenazine to the initial infusion and the F-A group for vice versa. The rate of CSF formation was measured at 3㎝ above zero outflow pressure by force transducer which connected to personal computer. After obtaining steady value of CSF formation rate, the drugs were infused intravenously according to the protocol. Base line CSF formation rate, 18.87±6.52μl/min, is reduced to 6.67±2.45μl/min after acetazolamide infusion and further reduced to 3.48±4.06μl/min after additional fluphenaxine. In fluphenazine group, the base line CSF formation rate, 16.34±4.58μl/min is reduced to 9.63±4.58μl/min after initial infusion of fluphenazine and further to 6.45±3.64μl/min, after additional infusion of acetazolamide. Mean reduction of CSF formation after initial intravenous infusion of acetazolamide and fluphenazine were 59% and 37% respectively. Although statistically insignificant, the CSF formation reduction in A-F group revealed more even and profound value comparing with that of F-A group. These date suggest that in addition to the effect of acetazolamide to reduce the formation of CSF, some other mechanism may exist in CSF formation that major tranquilizer exert the effect on CSF formation.

Information Technology의 기존 관광산업에 대한 영향 및 향후 Trend에 대한 전망 : 사이버여행사 수익모델을 중심으로 Profit Model of Cyber Travel Agency

조현준,나윤중,임형순,엄서호 한국문화관광학회 2001 문화관광연구 Vol.3 No.1

IT has an influence on the travel agency as chance and threat. The purpose of this study is to find what profit model of cyber travel agency. Ernst&Young's five business profit models that are based on target audience and transaction focus is selected to evaluated existing model of cyber travel agency. Those are off-line facilitator, gateway, context provider, commerce destination, online exchange. The result of this study show that there is no specific profit model in domestic cyber and on-offline travel agencies. Just Portal cyber travel agencies abroad have a few profit model. They have online exchange model, which are various target audience and abound provide contents.

가치사슬 관점에서 본 모바일 서비스 활성화에 대한 탐색적 연구

강윤정,이원준,김태웅 한국정보사회진흥원 2006 정보화정책 Vol.13 No.3

모바일 산업은 급속하게 성장하였음에도 불구하고 아직까지 모바일 서비스에 대한 수익이 그 기대에 못 미치고 있다. 이에 본 연구는 모바일 산업의 활성화를 위한 방안을 모색하고자 모바일 시장 상황을 각 시장 참여자의 관점에 서 이해하고자 한다. 모바일 서비스에서 부가가치를 창출하는 시장 참여자를 단말기 제조자, 콘텐츠 제공자, 네트워크 운영자로 크게 분류하고, 모바일 산업의 정책을 관여하는 정부/연구기관을 시장참여자에 추가하였다. 기존 연구를 토대로 모바일 산업의 당면과제를 수용 촉진 요인, 장애요인, 단말기 교체 요인 그리고 선결해야 될 과제로 구분하여 산업 종사자들을 대상으로 서베이조사를 하였다. 연구 결과 가치사슬 말단에 위치하여 사용자와 직접대면하고 있는 단말기 제조자들은 사용자의 관점과 유사한 시각을 나타내었으며, 상위에 있는 콘텐츠 제공자는 단말기 교체 요인에 있어 다른 시각 차이를 보였다. 해결되어야 할 현안에 대해서는 시장참여자들이 공통적으로 인식하고 있었다. 각 현안을 각 시장참여자들의 역할에서 살펴봄으로써 이를 해결하기 위해서는 시장 참여자들의 협력적 해결방안을 모색할 수 있는 단초를 제공하고 있다는 데 의의가 있다.

Nimodipine이 뇌척수액생성에 미치는 효과에 관한 실험적 연구

송준혁,박윤관,정흥섭,서중근,이훈갑,이기찬,주정화 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.9

The author has performed an experimental study in order to investigate the effect of nimodipine on the production of CSF in 12 cats. The cats were divided into 2 groups, one for nimodipine intravenous infusion and the other for its vehicle infusion group. Using ventriculo-cisternal perfusion method nimodipine and its vehicle were examined for their effects on CSF formation rate respectively. Baseline CSF formation rate was 22.5±2.9㎕/min(S.E.) and it gradually reduced to 17.0±3.4㎕/min(S.E.) after final infusion of nimodipine at 60㎍/㎏/min. Vehicle infusion revealed no significant change in CSF formation rate. Although the nimodipine insuion revealed declining tendency in CSF formation rate along with increment on nimodipine concentration, it was not statistically different from that of vehicle infusion group. Systolic blood pressure was significantly reduced after nimodipine infusion(133±31.8mmHg at baseline, 93.9±19.1mmHg at the end of the experiment) on oneway ANOVA test and it was significantly different from that in vehicle infusion group(p=<0.01).