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      • KCI등재

        유자액을 이용한 소스의 이화학적 특성 및 저장성

        유경미,서우영,서한석,김완수,박재복,황인경 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.4

        The purposes of this study were to investigate the physicochemical characteristics and storage stabilities of various sauces with added Yuza(Citrus Junos). Yuza consisted of three parts: peeled (46.17%), fleshed (43.74%) and seeded (10.09%). Yuza juice revealed 11.33% extraction yield, pH 2.85, 4.18% total acidity, 11° Brix, 1.16% transmittance and 2.63° Brix/acid ratio. Five kinds of sauces with added Yuza juice were Yuza red pepper paste sauce, Yuza soybean sauce for meat, Shahu shabu Yuza sauce, Korean Yuza vegetable sauce and Japanese Yuza soybean sauce. These sauces showed slight changes in pH, total acidity, total bacterial counts and overall sensory characteristics during storage period (60 days). In conclusion, Yuza juice could be applied to various sauces, which remained usable for 60 days.

      • 최대근력부하와 폭발적 근력부하에 의한 신경-근피로와 그 회복과정 비교 분석

        유관호,이무연,이승훈,김민섭,육조영,임정일,임완기,김대경 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

        The result which was gained from this study is as follows. From the conclusion of this study it was confirmed that resistant motion at high level strength brings about rise in density of lactate in blood at the same time decline of muscular power and generates acute fatigue of nerve-muscle accompanied by decline in electrical activity of muscle. On the other hand explosive loading produced fatigue at body center and decline in nervine-muscular activity particularly for men, In case of women explosive load did not produce fatigue in the same level as men and they were also quicker in recovery after exercise. Based on 2 types of loading method used in this study there was clearly difference in the process of restoration from resistant motion. For greater decline in muscular power and electromyogram activity more longer period of recovery was require.

      • 관상동맥 질환자를 위한 cycle ergometer exercise와 treadmill exercise의 적정 운동강도

        유승희,장완성,박찬호,김승환,노호성 경희대학교 체육과학연구소 2000 體育學論文集 Vol.28 No.-

        The purpose of this study was to determine heart rate (HR), ratings of perceived exertion (RPE) and oxygen uptake (Vo2) at the anaerobic threshold (AT) in two different exercise modalities, cycle ergometer and treadmil exercise (running). Subjects were 13 women patients with coronary heart disease. All sub-maximal and maximal Vo2 values but Vo2 at the AT for women were significantly higher in treadmill exercise than cycle ergometer. Submaximal and maximal HR values were not significantly different between the two exercise modalities. However, mean RPE values at the AT were significantly higher in cycle ergometer than treadmill exercise. We suggest that appropriate HR values in exercise training should be the same in cycling and treadmill exercise. while RPE values should be 1 or 2 higher in cycling than running.

      • Characterization of a Constitutive β-Lactamase from a Pseudomonas aeruginosa

        유진홍,허동호,최정현,김양리,신원식,강문원 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.2

        Objective : We analyzed some physicochermical chracteristics of a constitutive β-lactamase from a clinical isolate of a Pseudomonas aeruginosa which resistant to various β-lactams except imipenem and susceptible to aminoglycosides the proportion of its contribution to such resistance profile. Method : 1. Antimicrobial susceptibility test was done by the broth dilution method. 2. In hibition profile was done using EDTA, HgCl₂ and p-chloromercuribenzoate (pCMB). We also measured 50% inhibitory concentration(IC??) using β-lactamase inhibitors, such as clavulanic acid, sulbactam. 3. Kinetics study for substrate profile was performed by spectrophotometric assay using crude extracts and various antimicrobial agents. Relative hydropysis rates were determined. 4. The isoelectric point(pI) was determined by isoelectric focusing. The molecular weight was estimated by SDS-polycrylamide gel electrophoresis. Results : 1. The strain was resistant to ceftriaxone, sulperazon, piperacillin, ceftazidime, and aztreonam, while it was susceptible to gontamicin, tobramycin, amikacin and imipenem. 2. The β-lactamase was not inhibited by EDTA, and pCMB, whereas it was inhibited by HgCI₂. The IC?? of clavulanic acid was over 100μM and that of sulbactam was 22μM. 3. The relative maximal hydrolysis rate was calculated by setting V_(max) for cephaloridine at 100. The enzyme hydrolyzed cephalosporins more rapidly than penicillins. 4. The pI was 9.3 by isoelectric focusing. The molecular weight was estimated to be 40kDa. Conclusion : According to its substrate profile, pI and molecular weight, the β-lactamase from a clinical isolate of P. aeruginosa was a cephalosporinase belonging to group 1 in the Bush-Jacoby-Medeiros classification scheme.

      • KCI등재후보

        혈액질환 환자에서 조혈모세포 이식과 화학요법 후의 침습성 진균감염의 분석

        유진홍,최정현,이동건,최수미,신완식,김춘추 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

        목적 : 조혈모세포 이식이나 화학요법을 받은 혈액질환 환자에서 침습성 진균감염의 양상을 분석하고 예후 인자를 정하기 위하여 이 연구를 실시하였다. 방법 : 2000년 3월부터 2001년 2월까지 가톨릭 조혈모세포이식센터에 입원한 318명의 환자들 중 진균 감염으로 의심되어 항진균제를 투여받은 122명의 환자를 대상으로 후향적 분석을 실시하였다. 결과 : 74명의 환자가 EORTC/MSG 기준에 의해 침습성 진균증으로 판정되었다. 이들 중 6명이 확진이었고, 46명이 추정, 22명이 가능 증례이었다. 가장 많이 침습된 장기는 하부 호흡기이었다(72/74). 사망률은 32.4%이었다. 단변량 분석으로 예후 인자를 도출한 결과 입원 기간, 진단까지 걸린 시일, 그리고 amphotericin B의 총 투여량이 유의한 인자로 나왔다. 그러나 다변량 분석을 시행한 결과 입원 기간만이 독립적으로 유의하게 영향을 미치는 예후 인자로 산출되었다. 결론 : 침습성 진균 감염은 현재도 조혈모세포 이식이나 화학요법 후의 중요한 합병증으로 작용하고 있음을 알 수 있었다. 진균 감염 합병증의 예후에 영향을 미치는 요소로 입원 기간이외에 진단의 신속성과 항진균제의 투여도 유의한지에 대해서는 후속 연구를 통해 재치 규명해야 할 것으로 생각된다. Background : Invasive fungal infections (IFI) are one type of representing total infections in compromised patients. To analyze the characteristics and to determine the prognostic factors of IFI in patients with hematologic diseases undergoing hematopoietic stem cell transplantation (HSCT) and/or chemotherapy. Methods : We retrospectively reviewed consecutive patients (n=122) who received antifungal treatment with the impression of fungal infection complicating post-HSCT or chemotherapy from March-2000 to February-2001. Results : Seventy-four out of 122 registered patients belonged to the IFI on the basis of EORTC/MSG criteria. Six patients were proven IFI, 46 were probable, and 22 were in the category of possible one. The most commonly involved organ was lower respiratory tract (72/74). The mortality was 32.4%. Univariate analysis revealed duration of hospitalization, days to diagnosis of IFI, and total amount of amphotericin B as significant prognostic factors. But multivariate analysis determined only duration of hospitalization from these variables as an independently influencing factor on the prognosis. Conclusion : Invasive fungal infection is still the major threatening complication of HSCT and chemotherapy. Further follow-up and extension of this study is necessary to elucidate more prognostic factors.

      • KCI등재

        강원도 인제군 원대리 자연습지의 식물상

        박완근,유석인,박광서 강원대학교 삼림과학연구소 2000 Journal of Forest Science Vol.16 No.-

        강원도 인제군 남면 원대리 자연습지를 대상으로 1999년 4월부터 동년 10월까지 관속식물상을 조사한 결과 71과 175속 228종 1아종 33변종 3품종, 총 265종류가 분포하는 것으로 나타났으며, 이 가운데 갈대, 달뿌리풀, 삿갓사초, 골풀, 구릿대, 버드나무 등의 수생 및 관속식물은 19과 24속 31종 5변종 1품종, 총 37종류가 분포하고 있었다. 본 조사지역내 식생의 특성을 파악하기 위해 식물사회학적조사를 실시한 결과 갈대군락, 갯버들-횐물봉선아군락, 조팝나무-사철쑥아군락으로 분류되었다. This study was to estabilish the composition and vegetation of vascular plants on natural mashes in Wondae-ri(710m; 37˚ 58' 30" N, 128˚ 12' 15" E). This work was conducted from April to October, 1999. Vascular plants were composed of 71 families, 175 genera, 228 species, 1 subspecies, 33 varieties and 3 formae, totaling 265 taxa. Among the investigated vascular plants, 19 families, 24 genera, 31 species, 5 varieties 1 formae, totaling 37 taxa(13.9%) were hydrophytes and hygrophytes. The forest vegetation was classified Into 1 community and 2 subcommunities ; A.Phragmites japonica community A-1.Salix gracilistyla-Impatiens noli-tangere subcommunity A-2.Spiraea prunifolia var. simpliciflora-Artemisia capillaries subcommunity Key words : natural mashes, hydrophytes and hygrophytes

      • Cimetidine製劑의 分析方法에 관한 考察

        李琬夏,柳柄泰,延海壽 成均館大學校 1980 論文集 Vol.28 No.-

        The results on the analysis of cimetidine tablets and injections by UV determination, colorimetric determination and HPLC determination are as follows; 1. Cimetidine tablet can be easily made by wet granulation method and diluents in core tablets and film coating tablet do not interfere with analysis. 2. Cimetidine injections are made by aseptic manipulation or autoclaving. When they are adjusted approximately to pH 6.0 because they are stable under the strong acidic condition, they have high stability without the performance of complicated aseptic manipulation 3. UV determination shows more stable absorption spectrum by the Me-OH than by the 0.01-HCL as a solvent. It can be considered as a desirable quantitative analysis for cimetidine material. 4. Colorimetric derermination shows much better results by the BCG dye than by BTB dye. BCG dye doesn't be affected by diluents in tablets and preservatives in injections. 5. HPLC determination using the μBondapak C_18 column can be used for the quantitative analysis of cimetidine preparations. It shows the peak of main component in 1 minute after injection of sample. Compared with other analytical methods, HPLC determination is recognized as a desirable analytical method because of its high representation and short time for measuring the content uniformity in cimetidine preparations.

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