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VP-16으로 성공적으로 치료된 위 Kaposi 육종 1예
양웅석,송근암,조몽,이재승,송철수,김형욱,김영민,이수봉,김태오,이성훈 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4
The skin is an uncommon site of distant metastasis from any internal malignancy, and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% in patients with all systemic malignancies. Furthermore, cutaneous metastasis from adenocarcinoma of the stomach has been found to be extremely rare. A 35-year-old female patient was admitted due to multiple cutaneous nodules in her chest, abdomen, and back. A gastroendoscopic examination and biopsy was made according to the results of skin pathologic findings. Stomach and skin biopsy results revealed a signet ring cell type of adenocarcinoma. A case of gastric adenocarcinoma in which metastatic skin nodules appeared as the first sign of disease, is here in reported with a review of related literature.
( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.
Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예
백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2
Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy
도트 패턴 데이터베이스를 이용한 모델 기반 칼라 영상 중간조 처리 방법
이채수,박양우,장주석 경운대학교 산업기술연구소 1999 産業技術硏究論文誌 Vol.2 No.1
Model-based color image halftoning method using dot-pattern databases is proposed for low-resolution color image halftoning. The proposed algorithm has benefits of simple processing, less computational time of the ordered dither and benefits of aperiodic, uncorrelated structure without low-frequency graininess of the blue noise masking. The dot-pattern is defined as a part divided from a dot-profile, which is the binary pattern resulting from the halftoning of a constant gray level. In halftoning procedure, in order to improve the visual quality of the color halftoning, contrast sensitivity function (CSF) of human visual system is used. Using this CSF, the visual difference between original image and halftoned image can be computed as numerical value. Therefore, optimal dot-pattern can be selected from the database.
병기 2기와 3기 직장암 환자에서 수술 후 항암화학요법과 동시방사선화학요법
이호섭,김양수 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4
Background : Postoperative adjuvant therapy has been required in patients with operable rectal cancer because of risk of recurrence after surgery. Adjuvant therapies are known to chemotherapy (CTx), radiotherapy, and concurrent chemoradiotherapy (CCRT). Purpose of our study to compare the suvival rate, recurrence rate and toxicities between postoperative adjuvant CTx and CCRT in patients with rectal cancer after surgical treatment. Materials and Methods : This study involved 45 patients (CCRT; 15, median age; 58 years, range; 39-73) and CTx; 30, median age; 55 years, range; 36-67) with rectal cancer of stage II and III between April 2002 and May 2008. Treatment included six cycles of chemotherapy at 4-week intervals with fluorouracil 425mg/m2 and leucovorin 20mg/m2 administering continuous infusion for 24 hours during 5 days in CCRT group. Radiotherapy started on day 1 of the third chemotherapy cycle in CCRT. In CTx group, treatment included the same cycles of chemoterapy, and drug doses as in CCRT group. Results : Disease free survival (DFS) and Overall survival (OS) for 3 years were 68.4% and 70.8% in CCRT group and 82.5% and 80.5% in CTx group, respectively (DFS; P-value 0.997, OS; P-value 0.880). Recurrence rate including local recurrence and distant metastasis were 26.7% in CCRT group and 23.3% in CTx group (p-value 0.806). Local recurrence rates were 0% in CCRT group and 16.7% in CTx group (p-value 0.094). We investigated hematologic and non-hematologic toxicites. The incidence of radiation related proctitis was 26.7% in CCRT group and 0% in CTx group. But other toxicities were not significantly different between CCRT group and CTx group. Conclusion : DFS and OS were not different between CCRT group and CTx group in patients with rectal cancer of stage II and III. But local recurrence rate was lower in CCRT group than in CTx group. Toxicities were not differrent between CCRT group and CTx group, except the higher frequency of radiation related proctitis in CCRT group.
양완석,이수훈 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.1
This paper is on a new cutting force model which includes the force caused by unbalance. The cutting forces under the different additional masses are measured with the spindle speed changed. The model is justified through correlation between simulation and experimental result.
跆拳道 앞차기時 스탠스 差異에 따른 全身反應時間에 關한 硏究
李秀川,梁昌秀 慶北大學校 師範大學 體育學硏究會 1986 體育學會誌 Vol.14 No.-
The purpose of the study was to investigate changes of whole body reaction time in accordance with 3 different stances. The subjects were 3 male national caliber Tae Kwan Do players. The 3 different stances were 1 standard stance (natural stride of each subject), 2 comparable stance (natural stride of each subject-1/2 foot length, natural stride of each subject+1/2 foot length). The reselts were summarized as follow; 1. In case of subject A, the whole body reaction time were 0.223sec in standard stance, 0.325 sec in -1/2 foot length stance, and 0.364 sec in+1/2 foot length stance. But these were no significant differences except between standard stance and +1/2 foot length stance (p<0.5). 2. In case of subject B, the whole body reaction time were 0.446 sec in standard stance, 0.447 sec in +1/2 foot length stance, 0.473 sec in -1/2 foot length stance. There were not significant differences among the stances. 3. In case of subject C, the whole body reaction time were 0.374 sec in +1/2 foot length stance, 0.399 sec in standard stance, 0.405 sec in 1/2 foot length stance. But there were no significant differences among the stances. 4. In case of total stances, the whole body reaction time were 0.357 sec in standard stance, 0.395 sec in +1/2 foot length stance, 0.401 sec in -1/2 foot length stance. But there were no significant differences among the stances.
이영목,어수택,김양기 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Sweet's syndrome is a neutrophilic dermatosis that has various clinical characteristics and is often associated with inflammatory, malignant or autoimmune diseases, so the viral or bacterial antigens and tumor antigens are suspected to play a role in the pathogenesis of Sweet's syndrome. We describe here a Korean male who had Sweet's syndrome accompanied by anaphylaxis.