포괄수가지불제도 적용에 따른 산부인과 진료수입의 변화

황태연,유병철,정귀언,정수진,김성준,배기택,손혜숙,이종태,전진호,엄상화 인제대학교 2001 仁濟醫學 Vol.22 No.1

Objectives: Under the fee-for-service system, Korean hospitals have been suffering from the worsening profitability caused by law medical care fees. To overcome the difficulties, they have maximized the quantity of medical services and made relatively large investment in developing new medical services using high-priced medical equipment, medicines and medical supplies which were not covered by medical insurance system rather than reduced running costs. Materials and Methods: This study was made to analyze and forecast the revenue change of the department of Obstetrics and gynecology of an university hospital in Seoul, expecting the implementation of DRG system in 2000. Results: The results were as follows : 1.During the first two days of hospitalization. 41% of total medical service fee was occurred, which was thought that most of the check-ups and operations were made during this period. After two days of hospitalization, the new occurrence of medical service fee tended to reduce. 2.Out of total medical service fee, 67% of admission fee was occurred after 5 days of hospitalization. This was because medical service fees in obstetrics and gynecology department occurred during the first 5 days of hospitalization. 3.Out of fees for operation, treatment, medical supplies and blood transfusion. 71% was occurred during the first two days. 4. In case of fees for examination, 50% was occurred during the first two days. 5.A total of 53% of fees for medication and injection was occurred during the first 5 days. Conclusions: By the implementation of the DRG system, the income is forecast to increase by 800 won to 310,000 won by the disease group of obstetrics and gynecology department. To increase hospital income with the implementation of DRG system, the results of this study suggest that examinations should be done at out-patient departments before the hospitalization of patient, the discharge of patient should be noticed in advance to reduce the period of hospitalization, and admission appointment system should be implemented for the immediate operation and delivery.

Growth Inhibition of Colon Cancer through Inactivation of STAT3 Pathway by IL-10 and IL-1ra Released from Murine Macrophage

Jin Tae Hong, Dohee Won1, Mi Hee Park, Sun Mi Kown, Miran Jo, Sang-Yoon Nam, Beom Jun Lee, Young Won Yun, Ki-Wan Oh, Sang Bae Han 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.4

The objective of this study was to determine the effect of macrophages on growth of human colon cancer cells. The results showed that co-culture of colon cancer cells with macrophages inhibited the growth of colon cancer cells (HCT116 and SW620) depending on the number of macrophages, RAW 264.7 cells, and activated THP-1 cells accompanied by down regulation of pSTAT3 in cancer cells. We also found that expression and release of cancer cell growth inhibitory cytokines, IL-1 receptor antagonist (IL-1ra) and IL-10, was increased in macrophages. Blocking of the STAT3 pathway with specific inhibitor and siRNA of STAT3 abolished the growth of colon cancer cells and expression of IL-1ra and IL-10. In addition, neutralization of IL-1ra and IL-10 with antibodies resulted in reversal of macrophage-induced inhibition of cancer cell growth. These data showed that IL-1ra and IL-10 released from macrophages inhibit growth of colon cancer cells through inhibition of the STAT3 pathway

동북아 피더네트워크의 Win-win전략에 관한 연구

장우준(Woo-jun jang),전찬용(Chan-Yong jeon),김태원(Tae-Won Kim),곽규석(Kyu-Seok Kwak),남기찬(Ki-Chan Nam) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.3 No.1

최근 중국은 양산항을 개장하여 선사 유치를 위한 다양한 혜택을 제공하고, 일본은 "수퍼중추항만 육성계획“을 세워 항만의 효율성을 바탕으로 비용을 낮추려는 노력을 하고 있다. 또한 선박의 대형화에 의한 중심항만(Hub Port) 위주의 기항과 북중국의 대량 물량 발생지역에 대한 직기항 경향으로 동북아 항만간의 경쟁이 더욱더 치열해 지고 있으며 동북아 역내 피더네트워크 강화의 필요성이 제기되고 있다. 따라서, 본 연구에서는 유럽 피더네트워크 전략 사례를 바탕으로 동북아 피더시장 현황을 파악하고 동북아 피더네트워크 구조를 분석함으로써 동북아 역내 항만 및 선사간의 과당경쟁을 지양하고 서로 Win-Win할 수 있는 터미널의 전략적 활용, 선사간 제휴 확대, 항만간 협력 강화를 위한 구체적인 전략을 제시하였다. Recently, China opened Yangshan port and provides a variety of benefits for shipping companies. Japan plans to reduce logistics costs and improve efficiency through the established "super major ports" project. According to the "hub and spokes" system, the number of direct calls toward North-Chinese ports are increasing. This changing environment has negative effects on the amount of transshipment cargos in Korean ports. In order to make a hub port of a domestic port, it is necessary to develop northeast Asian feeder networks. Therefore, this paper analyzes the structure of northeast Asian feeder networks through the case study of European feeder networks strategy. Finally, we suggests the plans to reinforce feeder networks, which are strategic terminal operation, strategic alliances between shipping companies and port co-operation, for win-win strategy in the competitive northeast Asian market.

석탄 가스화를 통한 전력 생산과 DME 병산 공정에 대한 기초 경제성 분석

유영돈 ( Young Don Yoo ),김수현 ( Su Hyun Kim ),조원준 ( Won Jun Cho ),모용기 ( Yong Gi Mo ),송용택 ( Tae Kyong Song ) 한국화학공학회 2014 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.52 No.6

The key for the commercial deployment of IGCC power plants or chemical (methanol, dimethyl ether, etc.) production plants based on coal gasification is their economic advantage over plants producing electricity or chemicals from crude oil or natural gas. The better economy of coal gasification based plants can be obtained by co-production of electricity and chemicals. In this study, we carried out the economic feasibility analysis on the process of co-producing electricity and DME (dimethyl ether) using coal gasification. The plant’s capacity was 250 MW electric and DME production of 300,000 ton per year. Assuming that the sales price of DME is 500,000 won/ton, the production cost of electricity is in the range of 33~58% of 150.69 won/kwh which is the average of SMP (system marginal price) in 2013, Korea. At present, the sales price of DME in China is approximately 900,000 won/ton. Therefore, there are more potential for lowering the price of co-produced electricity when comparing that from IGCC only. Since the co-production system can not only use the coal gasifier and the gas purification process as a common facility but also can control production rates of electricity and DME depending on the market demand, the production cost of electricity and DME can be significantly reduced compared to the process of producing electricity or DME separately.

인터벌웨이트 트레이닝과 써키트웨이트 트레이닝의 效果에 關한 比較硏究

전태원,주기찬,임완기 師範大學 體育硏究所 1989 서울大學校 體育硏究所論集 Vol.10 No.2

The aim of this study was to verify comparatively the difference of the effects between I.W.T. and C.W.T. to the improvement in multilateral physicalfitness. To accomplish this purpose, the subjects consisted of 13 students in girls' middle school and they were divided into two groups by the way of random sampling: I.W.T. 7, C.W.T.6. Through 10 weeks' training in each group, such findings were gained as follows. 1. The improvement of Strength, Muscular endurance, were appeared significantly in both two groups. 2. The improvement of Power was appeared significantly in I.W.T. group, but not in C.W.T. group. 3. The decrease of % Body fat and Heart rate (at rest, in the load of 300kpm, 450kpm, 600kpm, were appeared significantly in both two groups. 4. Though the differance of effect between I.W.T. and C.W.T. was not appeared significantly in being compared by t-score, but the effect of I.W.T. was appeared much more significantly than the C.W.T. in being compared by % rate.

MC²학습 시스템이 인지능력에 미치는 영향

전태원,정청희,이강헌 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

The purpose of this study was to investigate the effect of the MC² learning systems on cognitive ability. Twenty male university students were sellected as subjects and were randomly assigned to both a control (10) and an experimental group (10). Subjects were then pre-tested for simple, and choice reaction time, movement time, short-term memory, probeability and concentration. The practice were for 30 minutes each, 3 days a week for 4 weeks. The finding of this study were as the follows. ① MC² learning system did not increase simple & choice reaction time. ② MC² learning system partly improved of movement time. ③ MC² learning system partly increased short-term memory. ④ MC² learning system did not increased probeability. ⑤ MC² learning system increased the concentration ablility. These test were done with limited subjects over very short experimental period and only a few programs were selected from among the whole MC² learning system. Therefore, more research will be required in well controlled laboratory & field situations to determine the long term effect of MC² learning system.

주요 우울증에서 종양괴사인자-베타 유전자의 다형성

전태연,배치운,김영호,장계호,이정태,박원명,김광수 대한신경정신의학회 2000 신경정신의학 Vol.39 No.6

연구목적 : 주요 우울증은 역학적 유전연구 등을 통하여 유전적 영향이 높은 것으로 알려져 있으며 최근에는 분자 유전학적 연구로 유전자 다형성과 질병의 연관성을 밝히는 것이 정신질환의 유전학적 연구에서 중요한 부분을 차지하고 있다. 이에 본 연구는 중추신경계와 면역계간의 상호작용에 관여하는 싸이토카인 중 TNF-β 유전자의 다형성을 분석하여 주요 우울증과의 유전학적 관련성을 알아보고자 하였다. 방 법 : DSM-IV에 의하여 주요 우울증으로 진단된95명을 환자군으로 선정하였고 가톨릭조혈모세포정보은행에서 보유하고 있는 정상 한국인 202명의 자료를 정상 대조군으로 사용하였다. 전혈에서 DNA를 추출하고 TNF-β 유전자 부위를 증폭한 후 제한효소 Nco Ⅰ으로 절단하여 555bp와 185bp의 절편을 갖는 TNFB*1과 Nco Ⅰ절단부가 없는 740bp의 절편 TNFB*2등 2가지 대립유전자의 제한효소절편길이 다형성을 조사하였다. 모든 자료의 분석은 x²검증을 이용하였다. 결 과 : 1) 주요 우울증과 정상 대조군 간에 TNFB유전자인 TNFB*1/1, TNFB*1/2 및 TNFB*2/2의 발현 빈도에는 유의한 차이가 없었다. 2) 두 군 간에 TNFB*1 과 TNFB*2 두 대립유전자의 빈도에는 유의한 차이가 없었다. 결 론 : 본 연구에서는 주요 울울증군과 정상 대조군 간에 TNFB*1과 TNFB*2의 두 대립유전자 발현 빈도에 유의한 차이를 발견하지 못하였다. 따라서 TNFB 유전자다형성과 주요 우울증과의 유전학적인 연관성이 없었다. 향후 연구에서는 다양한 임상변인을 포함하여 보다 통합적이고 체계적인 연구가 이루어져야 할 것으로 생각되었다. Objective : Major depressive disorder is known to have high genetic predisposition and the main focus of recent genetic studies in major depressive disorder has been concentrated on association studies between genetic polymorphism and disease, since molecular genetic methods have been developed. This study was designed to investigate the relationship between major depressive disorder and immunogenetic influences by analyzing polymorphism of TNFB gene, which is involved in interaction of immune system and CNS. Method : 95 persons who had been diagnosed of major depressive disorder were assigned as patient group and, 202 data obtained from Catholic hemopoietic stem cell bank, College of medicine, the Catholic University of Korea, were used as normal controls in this study. DNA was extracted from whole blood, thereafter amplified by polymerase chain reaction, and digested by Nco Ⅰ.After that procedure, we obtained and assessd restriction fragment length polymorphism of two alleles, TNFV*1 which has 555bp and 185bp fragments and carries the Nco Ⅰ restriction site, and TNFB*2 of 740 bp fragment lacks the Nco Ⅰ restriction site. All data were analyzed by x²test with two-tailed Fisher's exact test. Results : 1) The frequencies of TNFB*1/1, TNFB*1/2, and TNFB*2/2 were not statistically different between major depressive disorder patients and control group. 2) The frequencies of TNFB*2 and TNFB*1 were not statistically different between major depressive disorder patient group and normal control group. Conclusion : We did not verified the differences of frequency in TNFB*1/TNFB*2 gene between the major depressive disorder and normal controls, respectively. Consequently, there is no genetic relationship between major depressive disorder and gene polymorphism of TNFB. We do suggest that further systematic studies including various clinical variables should be conducted.

Tabu 탐색법을 이용한 PI 제어기 설계

원태현,황기현,문경준,이용길 동의공업대학 2000 論文集 Vol.26 No.1

We propose an adaptive Tabu search method changing neighbor solution's range to be searched each iteration according to an objective function and design a PI controller using the proposed Tabu search. We apply it to a time-delay system to evaluate the usefulness of the proposed method. overshoot, rising time, and settling time.

유 ·청소년의 최대산소섭취량과 무산소성 역치 추정에 관한 연구

전태원,이병근,정동춘 師範大學 體育硏究所 1993 서울大學校 體育硏究所論集 Vol.14 No.2

This study have two different purpose; one is to compare the cardiorespiratory function of male and female four student groups: elementary-, middle-, high-, and college level, the other is to produce the prediction equations for evaluating the maximal oxygen uptake and AT of the same groups. The all subjects in this study were 157: elementary school, middle school, high school, and college, is 49, 41, 28, 39 respectively. 1. Maximal Oxygen Consumtion 1) Body size components The body weight, FFW, VO₂max of both sex showed very high positive correlation:0.88∼0.94. However, male subjects’ slope was 8∼15% higher than that of females. On the other hand, Both male and female subjects’body weight, FFW and VO₂max/㎏ showed very low negative correlation:-.05∼ -.14. 2) Breathing components At the VO₂level, ?? was significantly low in accordance with the school levels; V?? of college level was most low among the four school levels. Minute ventilation(??) between male and female was neally same at the beginning stage of exercise. When their VO₂ reached at 1.5ℓ/min point, however, there was significant difference between male and female subjects’ ??. Like minute ventilation, male subjects’breathing rate(BR) was significantly lowered in accordance with the rise in school levels(p<.01). Female subjects BR, however, did not show significant difference among the four school levels although it was fewly decreased by the rise in school levels. 3) Circulation components The heart rate at every sumaximal intensity was significantly different between male and female, and among four levels of school as well. In other words, male subjects’submaximal heart rate was higher than that of female subjects by the rise in school level. Maximal heart rate, however, did not show significant sifference at all cases. Subjects’O₂pulse, compared at the point of VO₂1.0ℓ/min, did not show any significant difference between male and female, and among four grades as well. When it compared at the range of VO₂1.5∼2.5ℓ/min, however, there were significant differences between male and female, and among four levels of school as well. 4) The respiratory exchange ratio components The respiratory exchange ratio(R) at every sumaximal intensity was not significantly different between male and female, and among four levels of school as well. The respiratory exchange ratio(R) was increased gradually in accordance with the exercise intensity. 2. Anaerobic threshold The difference of AT-VO₂between male and female was gradually grown large by the level-up of their school levels; elementary school students had lowest AT-VO₂among four levels of school. There was not significant difference in AT-VO₂/㎏among four levels of school although AT-VO₂/㎏ was also higher in male than female. Like AT-VO₂,the difference of AT-HR between male and female was rapidly grown large by the level-up of their school levels. 3. The prediction equations of VO₂max, AT-VO₂and AT-HR Both male and female subjects’R and coefficients of variation of the prediction equations on VO₂max was 0.92∼0.95 and 10.8∼12.5% respectively. Both male and female subjects’R and coefficients of variation of the prediction equations on VO₂/㎏ was 0.40∼0.50 and 11.3∼16.0% respectively. Both male and female subjects’R and coefficients of variation of the prediction equations on AT-VO₂was 0.74∼0.88 and 6.6∼11.7% respectively. Both male and female subjects’R and coefficients of variation of the prediction equations on AT-HR was 0.52∼0.58 and 4.9∼6.7% respectively. Four prediction equations for each sex presented as follows. _______________________________________________________________________ VO₂max M Y=0.589+0.064AGE +0.021WT+0.003HT+0.358BSA ml/min F Y=-1.879+0.024AGE+0.039WT+0.025HT-1.587BSA _______________________________________________________________________ VO₂max /kg M Y=39.4+1.29AGE-0.50WT+0.04HT+5.57BSA ml/㎏/min F Y=-21.1+0.396AGE+0.343WT+0.857HT-65.63BSA _______________________________________________________________________ AT-VO₂ M Y=1.462+0.021AGE+0.029WT-0.011HT+0.157BSA l/min F Y=-0.199+0.019AGE-0.004WT-0.010HT+2.063BSA ________________________________________________________________________ AT-HR M Y=300.6-1.76AGE+0.31WT-0.79HT+5.73BSA beats/min F Y=270.6-2.063AGE-3.005WT-1.859HT+255.1BSA ________________________________________________________________________

전방 천골 수막류 - 증 례 보 고 -

박준석,신원한,김범태,변박장,최순관 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.11