방광 크롬친화세포종과 동반된 배뇨후 벼락두통

하윤석,강성진,허소영,이지현,김민정,김종국,김광수 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

Thunderclap headache is a hyperacute, severe headache that is so named because the pain strikes suddenly and severely, and is sometimes a sign of a medical emergency. We report a case of pheochromocytoma in the urinary bladder in a 48-year-old woman who presented with recurrent thunderclap headache after voiding and exercise. So we think thunderclap headache during or immediately after micturition may be an important diagnostic clue of bladder pheochromocytoma.

Clopidogrel에 의해 발생된 전신 염증 반응 증후군 1례

김민환,김종훈,박경일,박혜연,황철웅,김의석,도준형,남궁준,이성윤,이원로 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a 61 year old male patient who developed a systemic inflammatory response syndrome consisting of high fever, rash, chills, impaired liver function, and mild leukopenia after receiving clopidogrel after coronary angiography and stent implantation. The reaction resolved promptly after withdrawal of the drug, thus making the diagnosis of a clopidogrel induced reaction highly probable.

화학양론 조성 Mullite 의 합성과 그 소결특성

안석헌,정윤중,염희남,이종민 明知大學校 産業技術硏究所 1991 産業技術硏究所論文集 Vol.10 No.-

Stoichiometric mullite powder was prepared with Al(OH)₃, which was synthesized from Al₂(SO₄)₃·18H₂O and SiO₂, which was hydrolysised from TEOS(Al₂O₃:SiO₂=3 : 2 mole%), the sintered body of only mullite and the Y₂O₃ added mullite body were prepared and it's properties were detected. The results are follows. Crystalized mullite begins to founded from 1200 calaination and Well-Crystalzed mullite forms from the calcination temperature, 1300℃ . Crystal grains of mullite is accicular, and its relative density and bending strength of mullite ceramics which is sintered at 1650℃ are 92% and 180Mpa, respectively. As Y₂O₃ addtion the bending strength can be increased to 220MPa, because Y₂O₃ distribute and fill the vacancies of accicular mullite grain boundaries.

우울증 환자에 대한 Amineptine Hydrochloride의 임상 효과

강민희,신석철,왕성근,신윤오 최신의학사 1990 最新醫學 Vol.33 No.7

근관 전색재의 방사선 불투과성에 관한 비교연구

김태민,김서경,황인남,황윤찬,강병철,윤숙자,이재서,오원만 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.1

This study was performed to assess the radiopacity of a variety of root canal sealers according to the Specification concerning root canal sealers. Ten materials including Tubli-Seal™, Kerr Pulp Canal Sealer™, AH 26^(R), AH plus^(R), AH plus jet™, Ad seal™, Sealapex™, NOGENOU™, ZOB seal™, Epiphany™, and dentin were evaluated in this study. In the first part. densitometric reading of an each step of aluminum step wedge on occlusal film was performed at different voltage and exposure time. In the second part, ten specimens were radiographed simultaneously with an aluminum step wedges on the occlusal films under decided condition. The mean radiographic density values of the materials were transformed into radiopacity expressed equivalent thickness of aluminum (mm Al). The following results were obtained 1 Among the various conditions, the appropriate voltage and exposure time that meet the requirement density was 60 kVp at 0.2 s 2 All of the materials had greater radiopacity than 3 mm Al requirement of ANSI/ADA specification No. 57 (2000) and ISO No. 6876 (2001) standards. 3 The radiopacity of materials increased as thickness of materials increased. 4 The mm Al value of each specimen at 1mm in thickness has a significant difference in the statistics. It suggests that root canal sealers have a sufficient radiopacity that meet the requirement. 다양한 근관전색제는 방사선 사진상 주위 해부학적 구조와 구별될 만한 방사선 불투과성을 나타내야 한다 따라서 이런 물질들이 근관에 충전될 때의 방사선 불투과성 정도를 평가해야 할 필요성이 대두되고 있다. 본 실험에서는 다양한 근관전색제들의 방사선 불투과성을 평가하고자, 방사선 노출조건에 따른 aluminium step wedge에 대한 광학 밀도를 알아보고, 그 중 적절한 노출조건을 선택하여 수종의 근관 전색재의 방사선 불투과성 정도를 알루미늄 두께로 환산하여 비교해 보고자 한다. 방사선 불투과성의 기준을 위해 11개의 step으로 구성된 aluminum step wedge을 사용하여, 60kVP, 70kVp관전압 상태에서 각각 0.2, 0.3, 0.4초 그리고 0.2, 0.3, 0.33초의 꼭 노출시간으로 교합필름상에서 방사선 촬영후 적절한 노출 조건을 구하였다. 직경 5mm 각각의 두께 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 mm인 10종 (Tubli-Seal™, Kerr pulp Canal Sealer™, AH26^(R), AHplus^(R), AH plus jet starter kit™, Ad seal™, Sealapex™, Nogenol root canal sealer™, ZOB seal™, Epiphany™)의 근관전색재 시편을 각 재료와 두께당 10개씩 제작한 후, 동일한 두께의 상아질 시편, aluminum step wedge와 함께 정해진 노출시간에 따라 방사선 촬영을 하였다. 모든 필름은 자동현상기로 현상하였다. 시편의 방사선 흑화도를 densitometer로 5회 반복 측정 후, 평균값을 구하여 알루미눔 두께로 환산하였다.얻어진 정보를 분석하여 다음의 결과를 얻었다. 1 관전압 60 kVp에서 노출시간 0.2, 0.3, 0.4초, 70 kVp에서 0.2, 0.3, 0.33초로 변화를 주어 방사선 촬영을 하였을 때 흑화도가 ISO No. 6876 규격에 가장 적합한 것은 60 kVP, 0.2초 일 경우였다. 2 측정된 근관 전색제의 방사선 불투과성은 2.29 mm Al (N0GEN0L)로부터 13.69 mm Al (AH Plus jet)까지 다양하게 나타났으나, 모두 ANSI/ADA specification (2000) 또는 ISO No. 6876 (2001) 규격이 제시한 최소한 3mm Al 이상의 방사선 불투과성을 지녀야 한다는 기준에 적합하였다. 3 재료의 두께가 증가할수록 방사선 불투과성은 증가하지만, 정비례하지는 않았다. 4 각 실험재료의 1 mm 두께의 시편에 대한 mm Al값들은 통계적으로 유의한 차이가 있었다. 이상의 결과는 본 실험에 사용된 수종의 근관 전색재는 모든 규격에 적합한 방사선 불투과성을 가지고 있음을 시사한다.

기질성 정신장애환자에서 불안과 우울

신석철,왕성근,강민희,신윤오 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

Atuhors applied the self-rating anxiety scale(SAS) and the self-rating depression scale(SDS) devised by Zung to 95 psychiatric outpatients with organic mental disorder in order to investigate about anxiety and depression manifest in organic mental disorder and tried factor ananlysis using both test scores. 1. In SAS, 4 factors were extracted as paresthesia & facial flushing, fear & dizziness, palpitation & urinary frequency, and nervousness & fatigability. 2. In SDS, 4 factors were extracted as depressed affect & suicidal rumination, dissatisfaction & indecisiveness, fatigability & sleep distrubance, and emptiness & hopelessness.

Microfluidic generation of Prussian blue-laden magnetic micro-adsorbents for cesium removal

Kang, Sung-Min,Rethinasabapathy, Muruganantham,Hwang, Seung Kuy,Lee, Go-Woon,Jang, Sung-Chan,Kwak, Cheol Hwan,Choe, Sang-Rak,Huh, Yun Suk Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.341 No.-

<P><B>Abstract</B></P> <P>Here, we designed and synthesized a recoverable multifunctional adsorbent using a microfluidic reaction system and evaluated the removal performance of the smart adsorbent toward radioactive cesium as a model sample. Prussian blue-laden magnetic micro-adsorbents (PB-MNPs-MAs) with uniform morphology and monodispersity were generated via two-step sequential procedures using a glass capillary microfluidic system, followed by chemical co-precipitation with a high production rate. The cesium removal efficacy of the PB-MNPs-MAs was analyzed based on Langmuir and Freundlich isotherms by controlling adsorption parameters such as adsorbent size, initial cesium concentration, and contact time. The adsorption isotherm of the PB-MNPs-MAs was better fitted to the Langmuir model with a maximum cesium adsorption capacity of 58.73 mg g<SUP>−1</SUP>, which was 40% higher than that of macro-adsorbents in a dynamic magnetic field. This result can be attributed to their large specific area, which increased the kinetic rate of cesium adsorption and achieved saturation within 20 min. Additionally, the PB-MNPs-MAs were recovered from wastewater within 5 s under a static magnetic field, indicating their great potential for magnetic actuation. We believe that our PB-MNPs-MAs can encapsulate nano-functional adsorbents and prevent actuation, making them promising for environmental remediation and especially for removal of radionuclides.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PB-MNPs-MAs were generated in microfluidic device using chemical co-precipitation. </LI> <LI> The prepared PB-MNPs-MAs are monodispersed with uniform morphology. </LI> <LI> PB-MNPs-MAs exhibited high Cs adsorption capacity (58.73 mg g<SUP>−1</SUP>). </LI> <LI> 100% recovery of PB-MNPs-MAs is possible under static magnetic field after Cs adsorption. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

흰쥐에서 Cumambrin A의 대동맥 이완작용

홍용근,양민석,박윤배 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

We previously reported that the exogenous administration of cumambrin A, a sesquiterpene lactone from the dried flowers of Chrysanthemum boreale Makino has a pharmacological effect on normalization of blood pressure in the spontaneously hypertensive rats (SHR). In the present study, we further investigated the effect of cumambrin A on the relaxation of phenylephrine-induced precontracted rat aortic artery rings. The potency of cumambrin A was then compared to verapamil, a well known Ca^(2+)-channel blocker. The results demonstrate that the isolated rat aortic arteries are relaxed to basal tension at a concentration of 5X10^(-5)M cumambrin A treatment. The results also show that the phenylephrine-induced contraction is inhibited by a pretreatment of cumambrin A. Co-treatment of cumambrin A and verapamil showed a strong synergetic effect on the relaxation of rat aortic artery rings. Thus, these data demonstrate that cumambrin A is a potent relaxant of rat aortic smooth muscle and suggest that cumambrin A modulates intracellular or extracellular Ca^(2+) mobilization.

정신분열증에서 신경증적 증상의 임상적 의의에 관한 연구

박병관,신석철,강민희,신윤오 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

To investigate the clinical significance of the neurotic symptoms in schizophrenia, the author applied PSE(Present State Examination) on Screening Schedule to 153 schizophrenic patients who were fit for the aim of this study. The patients were divided into two groups to grasp the phenomenological characteristics as the group with neurotic symptoms (100 cases) and the group without neurotic symptoms(53 cases). Among 91 items except neurotic symptoms in PSE, 14 items were selected as significant under X²-test, and tried factor analysis with 14 items using SPSS/PC+. The results of this study were summarized as follows. 1. In the group with neurotic symptoms, 4 factors were extracted as slowness of speech and behavior and blunted affect factor, inappropriate answer and affect factor, delusion factor, and restricted and poverty of speech factor. In the group without neurotic symptoms, 5 factors were extracted as slowness speech and behavior and incoherence factor, inappropriate and poverty speech and self-neglect factor, delusion factor, inappropriate affect factor, and loss of affect factor. In the group of total patients, 4 factor were extracted as restricted and slowness of speech and behavior and blunted affect factor, delusion factor, inappropriate and poverty of speech and inappropriate affect factor, and incoherence factor. 2. In the group with neurotic symptoms, slowness of speech and behavior, inappropriate answer, blunted and inappropriate affect were the major symptoms and inappropriate answer and affect, delusion, restricted and poverty of speech were the minor symptoms. Among these symptoms, slowness restriction, poverty of speech and behavior, inappropriate answer and characteristic blunted affect were characterized by negative symptoms(i.e. defect state) which were frequent in chronic schizophrenia. 3. In the group without neurotic symptoms, slowness of speech and behavior, incoherence, and self-neglect were the major symptoms and inappropriate and poverty of speech, delusion, inappropriate and loss of affect were the minor symptoms. Among these symptoms, slowness and inappropriateness of speech and behavior, and characteristic incoherence and self-neglect were characterized by positive symptoms which were interpreted as less distorted reality than the group with neurotic symptoms in the process of schzophrenia. 4. In the group of total patients, restricted and slowness of speech and behavior, blunted affect and delusion were the major symptoms and inappropriateness, poverty and incoherence of speech, and inappropriate affect were the minor symptoms, which were composed of the major and the minor symptoms of the group with neurotic symptoms and without neurotic symptoms. These symptoms can be seen frequently in the diagnostic criterias and clinical practice and thought to be the result of the major symptoms common in schizophrenia regardless of he presence of neurotic symptoms.

초등학생에서 집단따돌림의 유병률과 이와 관련된 정신병리현상

김영신,고윤주,노주선,박민숙,손석한,서동향,김세주,최낙경,홍상의 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 학교폭력의 가장 흔한 형태인 집단따돌림은 피해아동 및 가해아동 모두에서 다양한 행동, 정서 및 사회적 문제와 연관되어 있는 것으로 알려져 있다. 본 연구에서는 지역사회내의 초등학교 고학년 학생들을 대상으로 집단따돌림의 유병률과 집단따돌림과 관련되어 아동에게 나타나는 정신병리 현상에 대하여 조사하고자 한다. 방 법 : 안양지역의 두 초등학교에서 무선으로 선출된 두 학급의 4, 5, 6학년 학생들이 본 연구의 연구대상이었다. 학생들은 한국형 또래지명설문지(K-PNI)를 완성하였고, 교사 및 부모는 ADHD Rating Scale(ARS)과 Conners 척도를 완성하였으며 부모들은 추가로 아동행동조사표를 완성하였다. 통계방법으로는 기술적 통계, 다중회귀분석 및 다중로지스틱 회귀분석을 사용하였다. 결 과 : 총 532명의 학생들이 본 연구에 참여하였다. 집단딸돌림의 피해자, 가해자 및 피해자 겸 가해자의 유병률은 각각 48%, 45%, 30%로 나타났다. 심한 집단따돌림의 유병률은 2.1∼4.1% 사이였다. 집단따돌림의 피해아동와 피해자 겸 가해아동들은 교사와 부모에 의해 부주의하고 수동적이며 사회적으로 미성숙하고 공격성이 있는 것으로 평가되었으며 학년이 올라 갈수록 피해자가 되는 경향이 적은 것으로 나타났다. 가해 아동은 행동문제와 관련되어 있었으며 남아에게 많은 것으로 나타났다. 결 론 : 집단따돌림은 한국 초등학교 고학년 학생들 사이에서 매우 흔하게 일어나는 현상으로 보인다. 집단따돌림의 경험을 한 아동은 그렇지 않은 아동에 비해 더 많은 정신병리 현상을 보였다. 이러한 정신병리와 집단따돌림과의 인과관계를 밝히기 위해서는 집단따돌림을 경험한 아동에 대한 추적 조사가 필요할 것이다. Objective : School bullying, the most prevalent type of school violence, is Know related to various behavioral, emotional and social problems both in victims and per The purpose of the present study is to investigate the prevalence of school bullying psychopathology in a community sample of elementary school students. Method : Fourth to 6^th graders of two randomly selected classes in two elementary Anyang City participated in a cross-sectional study. Study subjects completed Nominating Inventory(K-PNI). Parents completed Korean-Child Behavior Checklist(KADHD Rating Scale(ARS) and Conners Scales for parents, and teachers completed Conners Scales for teachers. Descriptive statistics, multiple linear and logistic regress performed. Results : A Total of 532 students participated in this study. Prevalence of victims, and victim-perpetrators were 48%, 45%, and 30% respectively. Extreme victims and of school bullying ranged from 2.1∼4.1%. Inattention-passivity in teachers' Conn social immaturity or aggression in K-CBCL were positively associated with victims perpetrators, and grade was negatively related to school bullying. Conduct problem in Scale for teachers and emotional instability in K-CBCL, and male gender were positively with perpetrators. Conclusion : School bullying is very common in Korean children of elementary Those who had experienced school bullying, either as victims or as perpetrators, cantly more psychopathology than their counterparts. To clarify a causal relationship psychopathology and school bullying, a longitudinal follow-up study is suggested.