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      • KCI등재

        보행 시 노인의 상체 움직임에 대한 3차원적 분석

        김희수,윤희중,류지선,김태삼 한국운동역학회 2004 한국운동역학회지 Vol.14 No.3

        H. S. KIM, H. J. YOON, J. S. RYU, T. S. KIM. The Three Dimensional Analysis of the Upper Body's Segments of the Elderly during Walking. Korean Journal of Sport Biomechanics, Vol. 14, No. 3, pp. 1-15, 2004. The purpose of this study was to investigate the kinematic variables of the upper part of the body for 8 elderly men during walking. For this study, kinematic data were collected using a six-camera (240Hz) Qualisys ProReflex system. The room coordinate system was right-handed and fixed in space, with righted orthogonal segment coordinate systems defined for the head, trunk, and pelvis. Based on a rigid body model, reflective marker triads were attached on the 3 segments. Three-dimensional Cartesian coordinates for each marker were determined at the time of recording using a nonlinear transformation(NLT) technique with ProReflex software (Qualisys, Inc.). Coordinate data were low-pass filtered using a fourth-order Butterworth with cutoff frequency of 6Hz. Three-dimensional angles of the head, trunk, and pelvis segment were determined using a Cardan method. On the basis of each segment angle, angle-angle plot used to estimated the movement coordinations between segments. The conclusions were as follows; (1) During the support phase of walking, the elderly people generally kept their head the flexional and abductional posture. Particularly, the elderly displayed little internal/external rotation. (2) The elderly people showed extensional and external rotation postures in the trunk movement. Particularly, It showed the change from adduction into abduction at the heel contact event of the stance phase. (3) The elderly people showed almost same pelvis movement from the flexion into extension, from the abduction into adduction, and from internal rotation into external rotation at the mid stance and toe off of the stance phase.

      • SSCISCIESCOPUS

        Associations of serotonergic genes with poststroke emotional incontinence

        Kim, Jae‐,Min,Stewart, Robert,Kang, Hee,Ju,Bae, Kyung‐,Yeol,Kim, Sung‐,Wan,Shin, Il‐,Seon,Kim, Joon‐,Tae,Park, Man‐,Seok,Cho, Ki‐,Hyun,Yoon, Jin‐ John Wiley Sons, Ltd 2012 INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY Vol.27 No.8

        <P><B>Objectives</B></P><P>Poststroke emotional incontinence (PSEI) has been associated with serotonergic dysfunction. Polymorphisms of serotonin transporter (5‐HTT) and serotonin 2a receptor (5‐HTR2a) genes may regulate serotonergic signaling at brain synapses, and this study was to investigate associations with PSEI in an East Asian population.</P><P><B>Methods</B></P><P>In 276 stroke cases, PSEI was diagnosed by Kim's criteria. Covariates included age, gender, education, history of depression or stroke, current depression, and stroke severity and location. Genotypes were ascertained for 5‐HTT gene‐linked promoter region (5‐HTTLPR), serotonin transporter intron 2 variable number tandem repeat, 5‐HTR2a 1438A/G, and 5‐HTR2a 102 T/C. Associations with PSEI were estimated by using logistic regression models, and gene–gene interactions were investigated by using the generalized multifactor dimensionality reduction method.</P><P><B>Results</B></P><P>PSEI was present in 37 (13.4%) patients. The 5‐HTT gene‐linked promoter region <I>s</I>/<I>s</I> genotype was independently associated with PSEI. No associations with STin2 VNTR and 5‐HTR2a genes were found, and no significant gene–gene interactions were identified.</P><P><B>Conclusions</B></P><P>Stroke patients with 5‐HTTLPR <I>s</I> allele had higher susceptibility to PSEI, which underlines the potential role of serotonergic pathways in its etiology. Copyright © 2011 John Wiley & Sons, Ltd.</P>

      • KCI등재

        두경부 마사지가 중환자실 환자의 수면과 불안에 미치는 효과

        김미용,전선영,송윤희,최은진,김재희,김미성,주명순,김남선 병원간호사회 2006 임상간호연구 Vol.11 No.2

        Purpose: This study was to apply head and neck massage to patients in intensive care unit and to inventigate the effect of that massage on sleep and state anxiety. Method: The subjects in this study were 27 patients who were admitted in medical intensive care unit. The study was performed from June thru September of 2005 on the One-group pretest-posttest design and the sleep, state anxiety of the subjects were measured before and after head and neck massage. For data analysis, paired t-test and Pearson correlation coefficient were utilized. Result: The first hypothesis that the subjects might have a better sleep after being exposed to head and neck massage was accepted. The second hypothesis that the subjects might feel less state anxiety afrer being exposed to head and neck massage was accepted. The third hypothesis that the sleep of the ICU patients maight be correlated to their anxiety was accepted, as there appeared correlation between their sleep and anxiety. Conclusion: Head and neck massage is identified as one of independent nursing interwentions to improve the sleep of ICU patients and ease their anxiety, and it is necessary to apply it to clinical practices.

      • S-542 Indomethacin aggravates the renal injury by inhibition of adenosine-medited renal protection in AKI

        ( Hyejung Kim ),( Sun-hee Kim ),( Mi Seon Kang ),( Park Seok Ju ),( Min Sung An ),( Ki Beom Bae ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

        Background: Ischemia-reperfusion injury (IRI) is a leading cause of acute kidney injury with high morbidity and mortality due to limited therapy. AKI emerges in various clinical settings and is complex with outcome linking oxidative stress, inflammation, and cell death. Therefore protection of AKI is still an unsolved problem. Indomethacin is generally known that it inhibits the production of prostaglandins through the inhibition both cyclooxygenase (COX) 1 and 2. Prostaglandins have a wide variety of effect such as regulation of vasodilation, inflammation, regeneration, pain, fever. Therefore effect of indomethacin in AKI is different according to injury model. We investigated whether indomethacin which inhibits the production of prostaglandins aggravate the renal injury in AKI mouse model. Methods: Male C57/BL6 mice (8-10 weeks old, weight 20~25 g) were used. Acute kidney injury is induced by bilateral kidneys pedicle clamping which were subjected to 20 min or 30 min at both kidneys. Mice were treated with indomethacin at before and after injury. Blood and kidney samples were collected at 24 hr after IRI. The expression level of creatinine, N-gal & Kim-1 were detected in serum. And the expression level of PGE2, cAMP and adenosine were detected in kidney. Kidney Injury score were measured by HE staining and TUNEL. Results: In bilateral AKI model, Serum NGAL level and creatinine level were significantly highest in indomethacin treated group compared to non-treated group (NGAL, p<0.05; creatinine, p<0.01). Indomethacin treated group showed significantly more necrosis and apoptosis compared to non-treated group. Furthermore, Indomethacine inhibited the production of prostaglandins, cAMP and adenosine. Conclusions: Indomethacin inhibits adenosine-mediated renal protection by inhibition of prostaglandin production in AKI. Therefore Indomethacin worsened renal injury by inhibition of prostaglandin production in AKI. * This research was supported by a grant of the Korea Health Technology R&D Project through the KHIDI, funded by the Ministry of Health & Welfare, Republic of Korea (grant number :H15C2212)

      • KCI등재
      • KCI등재

        북미지역주민(北美地域住民)의 사상체질(四象體質) 분포(分布)에 관(關)한 연구(硏究)

        Koh, Byung-hee,Kim, Seon-ho,Park, Byung-gwan,Lavelle, Jonathan D,Tecun, Marianne,Anthony Jr., Ross,Hobbs, Ron,Zolli, Frank,Chin, Kyung-hee 사상체질의학회 1999 사상체질의학회지 Vol.11 No.2

        In spite of recent remarkable recent development in both western and oriental medical sciences, there is still only a shallow understanding of individual differences for various prognoses of incurable diseases and immunopathy diseases. Nevertheless, the care, cure and prevention methods of Sasang Constitutional Medicine are broadly used as an effective treatment of incurable diseases like immunopathy diseases and stress-related diseases and diseases due to aging. In this sense, the establishment of classification norms is urgent and essential for the worldwide application of Sasang Constitutional Medicine(SCM). This study began with the confirmation process of whether Sasang Constitutional types exist in Americans. To accomodate for cultural differences, the distinguishing tool was readjusted so that Sasang Constitutional Types in Americans could be determined. Hence, the selected tool is the new QSCCII+, which is a newly revised English version of the QSCCII. QSCCII was made and standardized by Dept. of SCM in Kyung Hee Medical Center and Dr. Kim7). The evaluation methods of the old version were improved in the new QSCCII+ through necessary statistical manipulation. The original QSCCII was officially authorized by the Korean Society of Sasang Constitutional Medicine as the only computerized version of Sasang diagnostics. This study is the first attempt to design a new diagnostic tool for the classification of Sasang Constitutional types in North Americans with the revision of QSCCII. The subjects of this study were selected from the cooperative people among the students and staffs of the University of Bridgeport and the patients who visited the Clinic in the Health Science Center. This study takes for about 1 year from 1998. 8 to 1999. 8 The conclusions of the study can be summarized as follows: 1. Sasang constitutional types also exist in Americans. It can also naturally be inferred that Sasang Constitutional types exist in all human beings, for there are many different human races in America. 2. There are more So-Yang In's than any other types in American white people. This result confirms the hypothesis that there also exist Sasang Constitutional types in westerners. 3. The result of repetitive tests suggests that the new QSCCII+ is an effective diagnostic tool for westerners when we consider the constant diagnostic results of the QSCCII+. 4. Sasang Constitutional types exit in the sample group regardless of racial difference. 5. The question items that were not often checked by Americans need to be modified into more understandable expressions. 6. The standardization of diagnosis for Americans should be established by use of the QSCCII+ 7. It can be guessed that there are many Tae-yang In's among the 71 persons who could not be clearly classified by the QSCCII+. Due to the scarcity of Tae-yang-In in general, it is important to improve upon the discernability of the QSCC II+. 8. The results of the Sasang Constitutional distribution in North Americans are as follows: The percentage of So-yang In distribution in the sample group is 36.25%(87persons), that of Tae-eum In is 13.75%(33persons), and that of So-eum In is 20.41%(49persons). 동(東) 서양의학(西洋醫學)이 여러 방면(方面)으로 눈부시게 발전(發展)해 왔음에도 불구(不拘)하고 동일질병(同一疾病)에 대한 약(藥) 효과(效果)의 개인별(個人別) 차이(差異)나 질병(疾病)에 대한 개인별(個人別) 감수성(感受性)의 차이(差異)에 따른 여러 가지 면역관계(免疫關係) 질환(疾患)의 다양성(多樣性)이나 난치병(難治病)의 다양(多樣)한 예후(豫後) 등(等)의 이유(理由)를 정확(正確)히 이해(理解)하지 못하고 따라서 적절(適切)한 대처(對處)를 하지 못하고 있는 것이 현실(現實)이다. 그런데 사상의학(四象醫學)의 네 체질(體質)에 따른 질병(疾病) 관리(管理), 치료(治療) 및 예방법(豫防法)은 현대(現代)의 난치병(難治病)이라고 할 수 있는 성인병(成人病), 면역계(免疫係) 질환(疾患), 스트레스성(性) 질환(疾患)의 관리(管理)에 효과적(效果的)으로 적용(適用)할 수 있으므로 현재(現在) 한방임상의학(韓方臨床醫學)에서 많이 응용(應用)되고 있다. 이러한 사상의학(四象醫學)을 세계(世界)에 폭넓게 적용하기 위해서는 국제적(國際的)으로 응용(應用)할 수 있는 체질진단(體質診斷)의 기준(基準)이 마련되어야 한다. 우선(于先) 본(本) 연구(硏究)는 외국인(外國人)에게도 과연(果然) 체질(體質)이 존재(存在)할까 하는 의문점(疑問点)을 해결(解決)하기 위(爲)하여 미국인(美國人)을 대상(對象)으로 체질(體質) 분류(分類)를 시도하여 체질(體質) 존재(存在) 여부(與否)를 확인(確認)하는 작업(作業)부터 시작(始作)하였다. 또 체질(體質)이 존재(存在)한다면 체질(體質) 진단(診斷) 도구(道具)로는 어떤 것이 좋을까를 알아보기 위(爲)한 연구(硏究)를 병행(竝行)하였다. 선택(選擇)된 체질(體質) 진단(診斷) 도구(道具)로는 경희대학교(慶熙大學校) 사상의학(四象醫學) 교실(敎室)에서 개발(開發)되어 학회(學會)에서 공인후(公認後) 임상(臨床)에서 널리 사용(使用)되는 체질(體質) 진단(診斷) 도구(道具)인 QSCCII를 바탕으로 이를 영문(英文)으로 번역(飜譯)하고 채점(採點) 방법(方法)을 보완(補完)하여 새롭게 제작(製作)된 new QSCCII + 사용(使用)하였다. 본(本) 연구(硏究)는 국내(國內)에서 표준화(標準化)되어 사용(使用)하고 있는 체질진단진단도구(體質診斷診斷道具)인 QSCCII를 보완하여 미국(美國)에서 응용(應用)할 수 있는 새로운 진단(診斷) 도구(道具)를 마련하고자 처음으로 시도(試圖)된 연구(硏究)이다. 조사(調査) 대상(對象)은 University of Bridgeport. Connecticut. U.S.A의 학생(學生), 교직원(敎職員)그리고 Health Science Center의 Clinic을 방문(訪問)한 사람중(中) 본(本) 조사(調査)에 협력(協力)한 사람이 주(主)로 그 대상(對象)이 되었으며 기타(其他) 주변(周邊)의 현지인(現地人)들이 대상(對象)이 되었다. 년(年) 조사대상인원(調査對象人員) 344명(名)이었고 전체(全體) 조사(調査) 대상(對象)에서 재검사(再檢査)를 할 수 있었던 인원(人員)은 240명(名)이었다. 연구기간(硏究期間)은 1998년(年) 9월(月)부터 1999년(年) 8월(月)까지 약(約) 1년(年) 여(餘)에 걸쳐 실시(實施)되었다. 이러한 연구결과(硏究結果)를 고찰(考察)해 볼 때 아래와 같은 결론(結論)을 얻었다. 1. 미국(美國) 사람에게도 사상체질(四象體質)은 존재(存在)한다. 추론(推論)컨데 미국(美國)에는 다양(多樣)한 인종(人種)이 섞여 살고 있으므로 외국인(外國人) 모두에게 역시(亦是) 체질(體質)이 존재(存在)한다고 볼 수 있다. 2. 미국인(美國人)에게 특(特)히 백인(白人)에게

      • 光陽地域 金屬鑛床에 대한 岩石學的 및 鑛物學的 硏究

        金熙南,柳官善 조선대학교 기초과학연구소 1986 自然科學硏究 Vol.9 No.1

        The studied area is lobated in the central part of Kwang-Yang, Chullanamdo, which is in the south west of the Gyeongsang basin, The geology consists of the Pre-Cambrian Jirisan gneiss complex as its country rock, covered with the Gyeongsang system sedimentary rock giving unconformity in the Cretaceous period, and is intruded by volcanic rocks and plutonic jgneous rocks. These deposits are fissure filling hydrothemal ore deposits which were formed through fissure with the strike N 20^˚~50^˚E and the dip 70^˚~85^˚SE in the Pre-Cambrian Jirisan gneiss complex. They consist of gold, silver, and quartz veins. Ore minerals are chalcopyrite, arsenopyrite, pyrrhotite, pyrite, galena, sphalerite, native gold, bornite, and covellite. The source rock of the ore minerals is granite porphyry, plutonic igneous rocks intruded in the late Cretaceous period. The method of study is as follows: 150 pure rock samples and 50 ore samples were picked up around the deposits and outcrops, and classified according to the distributed areas and their kinds. 80 thin sections out of 150 rock samples and 40 polished sections out of 50 ore samples were made and a modal analysis were made of them each. And 10 out of the thin sections were made chemical analysis. 5 out of the polished sections were made X-Ray diffraction analysis, which made a verification of what kind of ore minerals are contained in them. As a result of the modal analysis, the granite rocks ill the studied area are plotted by quartz monzodiorite, and have the similarity of the Bulgugsa granite rocks, and its gneiss is plotted by granodiorite and is similar to the Hongjesa granite gneiss. From the results to the Hongjesa granite gneiss but are poor in SiO_2 and rich in FeO, MgO and MnO, For this reason, it is thought that these rocks contain the minerals of the garnet group. These rocks belong to the alkali-calcic rock series in the alkali lime index composed by Peacock. By the I-S type classification by White, Chappell(1977) and Hine(1978) and by the A C F diagram and the normative’s Qu-Or-Ab triangular diagram, these rocks originated from sedimentary rocks. The Proportion of the alk:fm of the Niggli mean value is 19:46, and these rocks were possibly generated from before the Bulgugsa granite and Masan granite age. From the AMF diagram these rocks are coincident with the Gyeongsang basin trend in granite and similar to the Hyndmann trend in gneiss. In the AKF diagram and normative Or-Ab-An diagram, the rocks in the studied area are rich in albite, and compared with S.R. Nockold’s world rock mean value, they belong mostly to tonalite and diorite.

      • 제주도 한라산 1100 고지 대기 에어로졸의 조성 및 특성

        김원형,강창희,신찬성,고선영,홍민선 濟州大學校 基礎科學硏究所 2003 基礎科學硏究 Vol.16 No.1

        The atmospheric aerosols collected at the 1100 site located in Mt. Halla have been analyzed to investigate their compositions and chemical characteristics. The average concentrations of water-soluble cautions were in the order of NH_(4)^(+)>Ca^(2+)>Na^(+)>K^(+)>Mg^(2+) during the spring, showing high increase of Ca^(2+) concentration with the value of 0.60㎍/㎥, and NH_(4)^(+)>Na^(+)>K^(+)>Ca^(2+)>Mg^(2+) during the other seasons. The average concentrations of anions have shown in the order of SO_(4)^(2-)>NO_(3)^(-)>Cl^(-) for all seasons, and SO_(4)^(2-) and NO_(3)^(-) had higher concentrations in spring with the values of 4.84㎍/㎥ and 1.08㎍/㎥, respectively. From the analytical data of size-segregated particles by cascade impactor sampling, the components of NH_(4)^(+), SO_(4)^(2-), NO_(3)^(-) and K^(+) were distributed mainly in fine particles, but Ca^(2+), Na^(+), Mg^(2+) and Cl^(-) were included mostly in coarse particles. The correlation coefficients of nss-SO_(4)^(2-)/NH_(4)^(+), nss-SO_(4)^(2-)/K^(+) and NO_(3)/nss-Ca^(2+) showed quite high values with 0.871, 0.857 and 0.654, respectively. Based on the study of enrichment factors, it is considered that Na^(+), Mg^(2+), Cl^(-) and Ca^(2+) components were delivered from oceanic and soil sources, but SO_(4)^(2-), NO_(3)^(-) and NH_(4)^(+) might have other source origins. The factor analysis study showed the aerosol at the 1100 site was influenced mainly by anthropogenic factors, followed by oceanic and soil factors.

      • KCI등재

        유치열 아동의 교합양상및 측모에 관한 역학적 연구

        김선미,양규호,김선희 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.1

        The occlusal patterns and profiles of the primary dentition were studied by oral examination from 3 to 6 year-old children (100 boys, 100 girls) in Kwangju city. The results were as follows : 1. In sagittal primary second molar relationship, mesial step(48%) and flush terminal plane relationship (47.5%) were prevalent. 2. In profile view, straight profile (57%) was prevalent. 3. In comparison of relationship between primary second molar relationship and profile, Class 1 pattern-straight profile (31 boys, 32 girls) was prevalent.

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