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      • 혈전성 혈소판감소성 자반증으로 발현된 전신홍반루푸스 1예

        오명근,유미라,변유미,윤찬영,권세훈,박치영,김상현 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

        Thrombotic thrombocytopenic purpura (TTP) is a life-threatening syndrome characterized by the classic pentad of clinical features that includes microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Early diagnosis and utilization of plasmapheresis can improve the survival rates of patients with TTP. TTP rarely may be seen in association with autoimmune disease such as systemic lupus erythematous (SLE). We report here a 42-year-old female who was presented with severe digital gangrenes, microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal dysfunction. Her condition responded to combined therapy with high dose steroid, immunosuppressants, and plasmapheresis therapy.

      • 선천안진의 수술적 치료

        오세오,최미영 충북대학교 의과대학 충북대학교 의학연구소 1996 忠北醫大學術誌 Vol.6 No.2

        선천안진 환자에서 수술적 치료의 목적은 일반적으로 안진에 의해 속발하는 머리회전을 교정하기 위함이다. 수술에 의한 안진 정도의 감소와 이에 따른 시력 개선에 관하여는 보고된 바있으나 아직 확실하게 밝혀지지 않았다. 저자들은 안면회전들 동반한 선천안진 환자에서 수술적 교정을 통하여 정상적인 머리위치와 의미있는 시력개선의 효과를 얻을 수 있었던 3예를 경험하였기에 문헌고찰과 함께 보고하는 바이다 Surgical treatment of congenital nystagmus may be aimed to eliminate a compensatory head posture and/or to improve binocular visual acuity by decreasing nystagmus amplitude. We performed augmented Kestenbaum procedure to eliminate a abnormal head turn and four recti muscles recession to decrease nystagmus amplitude in three cases. After the surgical intervention, head turn was disappeared and visual acuity was improved.

      • KCI등재

        과학사적 진화개념 발달 단계에 기초한 초등학생들의 진화 개념 분석

        이미숙,오세평,이길재 한국초등과학교육학회 2005 초등과학교육 Vol.24 No.2

        Students' alternative concepts of evolution are similar to misconcepts and disputes which scientists had in science history. The aims of this study are to analyze the elementary children's concept in evolution based on science history. Lee (2004)'s two tests were applied to 6th grade to investigate the children's evolution concepts and genetic concepts related to the historical development of the evolution concepts. The test results were analyzed in accordance with 4 stages of science history based on Lee (2004)'s method. These stages are divided to stage 1 (Before Lamarck), stage 2 (Lamarck), stage 3 (Darwin), stage 4 (After Darwin). The major results are as follows. Most of elementary school children are fixed to the stage 2. They usually do not show the consistency of evolution concepts in the three dimensional aspects such as mechanism, time, and subjects. Many children do not have concrete meaning of gene, inheritance, sexual reproduction, mutation and could not connect these concetps and process of evolution. Also, they believe the inheritance of acquired traits and spontaneous generation. Therefore it is confirmed that they still have similar misconcepts and disputes which scientists had in transition time between stage 2 and 3 and most of children already have strong Lamarckian thought acquired from daily life experience before learning about natural selection and evolution.

      • 해리수직편위의 치료

        최미영,오세오 충북대학교 의과대학 충북대학교 의학연구소 1997 忠北醫大學術誌 Vol.7 No.1

        해리수직편위에서 수술적 치료의 목적은 상방편위된 눈에 의한 미용상의 문제를 해결하기 위함이다. 여러 가지 수술 방법이 보고된 바 있으나, 수술에 의한 합병증이 동반되고 있다. 이에 저자들은 해리수직편위 환자에서 양안성, 편위정도, 그리고 주시형태에 따라서 가림치료 및 수술적 치료를 시행하였다. 가림치료를 통하여 미용문제를 개선할 수 있었으며, 수술적 치료에 있어서 최소한의 상직근 후전술을 통하여 상방편위를 교정할 수 있었기에 문헌고찰과 함께 보고하는 바이다. The cosmetic importance of surgical management of manifest dissociated vertical divergence has been agreed upon, but a number of different operative approaches have been cited in the literature. However these procedures have had significant problems. Therefore we undertook occlusion treatment or superior rectus muscle recession according to bilaterality, amount of deviation, and fixation preferene. A good result in cosmetic problem is achieved when unilateral dissociated vertical divergence and bilateral disease with dominant fixation. Superior rectus musc1e recession of 4-7mm was the satisfactory successful treatment.

      • 근관세척액의 세포독성 효과

        임미경,정희일,오세홍 원광대학교 생체재료·매식연구소 1995 원광생체재료·매식 Vol.4 No.1

        Balance between antibacterial effectiveness and biocompatibility is important property of root canal irrigation solutions. The aim of this study was to evaluate the cytotoxic effect of irrigation solutions on cultured L929 cells. Seven irrigation solutions and thier serial dilution solution were applied to L929 cells. Radiochromium release of damaged L929 cells after five-minute, thirty-minute and four-hours exposure to each irrigation solutions were monitored using gamma particle counter. L929 cells which were exposed to 1:1 and 1:10 diluted solutions of sodium hypochlorite and cresol for five and thirty minutes showed cytotoxic change. Povidone had cytotoxic effect on L929 cells after five minutes, thirty minutes and four hours. Normal saline, alcohol, Wydex and hydrogen peroxide showed weak cytotoxic effect on L929 cells.

      • KCI등재

        허혈성 장질환의 조기진단을 위한 혈청 락테이트(lactate)의 유용성

        이미진,오동렬,박규남,김세경,양진홍,박상현 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

        Background: Intestinal ischemia remains a devastating event despite improvements in clinical recognition and in diagnostic and therapeutic modalities. The ischemic bowel diseases encompass a wide clinical spectrum from mild, reversible disease to severe, irreversible injury. The clinical picture is characterized initially by poorly localized visceral pain. Thus, it is difficult to diagnose this ischemia at an early stage. This study investigated whether an increased serum lactate level is a recognized danger signal marker for intestinal ischemia in patients who present at the emergency department because of abdominal complaints. Methods: Patients who came to our emergency department with abdominal pain and the risk factors of intestinal ischemia between Apr. 1999 and Nov. 1999 were included in this study. The data analysis included age, sex, final diagnosis, pathogenesis of bowel ischemia, and serum lactate level. Results: The serum lactate level in the intestinal ischemia group was 28.54±22.51 mg/dl; in non-ischemia group, it was 15.49±22.52 mg/dl. This difference between the two groups was significant(p<0.05). An increased serum lactate level had a sensitivity of 88.2% and specificity of 59.2%, a positive likelihood ratio of 4.92, and a negative likelihood ratio of 0.47 as a marker of bowel ischemia. These results do not represent a very meaningful revision of bowel ischemlc provability, but may make a small contribution to management of the disease, depending upon their magnitude and the clinical context in which they are applied. Conclusion: In patients with abdominal complaints, an increased serum lactate level is usually a useful aid as a diagnostic marker of bowel ischemia.

      • 이미지 데이터베이스를 위한 정보 검색 시스템의 설계 및 구현

        김만순,오세봉,김미연,민은미,박미영,정문숙,문현수,김상욱 강원대학교 정보통신연구소 2002 정보통신논문지 Vol.6 No.-

        This paper presents design and implementation of an information retrieval system for a large volue of an image database. Our system supports three kinds of queries: attribute-based queries, keyword-based queries, and color-based queries. The attribute-based query is the most-typical query that finds target images based on their attribute values. The keyword-based query is to find target images by referring to their description information their attribute values. Finally, the color-based query is to search for target images by comparing the colors of a query image with those of images in the database. In this paper, we presents the system architecture and approaches adopted in our system for supporting the above three queries effectively and efficiently. We also discuss the user interface of our system that enables users to manipulate our system easily and conveniently.

      • KCI등재

        급성 신우신염 환자에서 혈액배양의 유용성

        박상현,이미진,오동렬,김세경 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

        Background: Routine cultures of blood in febrile patients being hospitalized with uncomplicated pyelonephritis are parts of accepted management and are advocated in several textbooks of medicine and in several review articles, For a better understanding of the importance of blood cultures for patients admitted with pyelonephritis, we did a retrospective chart review of patients admitted to a medical center over a 2-year period. Methods: To evaluate the usefulness of blood cultures in patients admitted with pyelonephritis, we conducted a retrospective chart review of patients who were admitted to hospital from 1998 through 1999 with a primary discharge diagnosis of uncomplicated pyelonephritis. Results: Among the 329 patients admitted, 177 patients were included in the study. Sixteen(9.0%) were men, and 161(91%) were women. The mean age was 52.24±18.08. The most common precipitating factor was diabetes mellitus (19.2%). Urinalysis results showed E.coli as the causative agent in 155 patients(87.6%). Positive blood culture results were be seen in 67 patients with a 37.9% sensitivity. The usefulness of blood cultures in acute pyelonephritis was statistically significant only in the case of fever(P=0.003). Conclusion: In the setting of uncomplicated pyelonephritis in the adults, if urine cultures can be obtained, blood cultures are not usually necessary. Settings where blood cultures might be appropriate include immunosuppressed patients, patients in whom the diagnosis is not clear, patients in whom bacteremic seeding of the kidney is suspected, and patients who have a prior history of urinary tract infection,

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